کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6069173 | 1587145 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibiotic Allergies in Children and Adults: From Clinical Symptoms to Skin Testing Diagnosis
ترجمه فارسی عنوان
آلرژی آنتی بیوتیک در کودکان و بزرگسالان: از علائم بالینی به تشخیص تست پوست
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کلمات کلیدی
DPTDrug provocation testsSJSAGEPCLVLTTBATβ-lactam - β-لاکتامAllergy - آلِرژیAmoxicillin - آموکسیسیلینAmpicillin - آمپی سیلینAntibiotics - آنتی بیوتیک هاClavulanic acid - اسید کلوولانیکAdults - بزرگسالانBenzylPenicillin - بنزیل پنی سیلینlymphocyte transformation test - تست تحول لنفوسیتHypersensitivity - حساسیت بیش از حدDrug - داروten - دهStevens-Johnson syndrome - سندرم استیونز-جانسونImmediate - فوریDRESS - لباسToxic epidermal necrolysis - نکرولیز اپیدرمال سمیAcute generalized exanthematous pustulosis - پاستولوز عجیب و غریب به طور کلی عمومیChildren - کودکان
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
Hypersensitivity reactions to β-lactam and non-β-lactam antibiotics are commonly reported. They can be classified as immediate or nonimmediate according to the time interval between the last drug administration and their onset. Immediate reactions occur within 1 hour after the last drug administration and are manifested clinically by urticaria and/or angioedema, rhinitis, bronchospasm, and anaphylactic shock; they may be mediated by specific IgE-antibodies. Nonimmediate reactions occur more than 1 hour after the last drug administration. The most common manifestations are maculopapular exanthems; specific T lymphocytes may be involved in this type of manifestation. The diagnostic evaluation of hypersensitivity reactions to antibiotics is usually complex. The patient's history is fundamental; the allergic examination is based mainly on in vivo tests selected on the basis of the clinical features and the type of reaction, immediate or nonimmediate. Immediate reactions can be assessed by immediate-reading skin tests and, in selected cases, drug provocation tests. Nonimmediate reactions can be assessed by delayed-reading skin tests, patch tests, and drug provocation tests. However, skin tests have been well validated mainly for β-lactams but less for other classes of antibiotics.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 2, Issue 1, JanuaryâFebruary 2014, Pages 3-12
Journal: The Journal of Allergy and Clinical Immunology: In Practice - Volume 2, Issue 1, JanuaryâFebruary 2014, Pages 3-12
نویسندگان
Antonino MD, Jean-Christoph MD,