کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9225584 1201994 2005 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Keratinocyte-derived, CD80-mediated costimulation is associated with hapten-specific IgE production during contact hypersensitivity to TH1 haptens
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Keratinocyte-derived, CD80-mediated costimulation is associated with hapten-specific IgE production during contact hypersensitivity to TH1 haptens
چکیده انگلیسی
These data suggest that keratinocyte-derived costimulation mediated by B7-1 but not B7-2 results in the emergence of TH2-lymphocyte immune responses to TH1 haptens. Because human keratinocytes have been noted to express B7-1-like molecules in certain inflammatory skin diseases, this model may be important in understanding the pathophysiology of TH2-lymphocyte-mediated skin diseases such as atopic dermatitis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 115, Issue 2, February 2005, Pages 383-390
نویسندگان
, , , , , , , ,