Iontophoretic Transdermal Delivery of Sumatriptan: Effect of Current Density and Ionic Strength Fulltext Access 4 Pages 2005
A novel role for parkin in trauma-induced central nervous system secondary injury Fulltext Access 4 Pages 2005
Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: Potential advantages over antibodies expressed within the intracellular environment (Intrabody) Fulltext Access 4 Pages 2005
Transplanted human embryonic stem cells as biological 'catalysts' for tissue repair and regeneration Fulltext Access 4 Pages 2005
Do vasoactive neuropeptide autoimmune disorders explain pyridostigmine's association with Gulf War syndrome? Fulltext Access 4 Pages 2005
A chronic dysfunctional stress response can cause stroke by stimulating platelet activation, migraine, and hypertension Fulltext Access 4 Pages 2005
Possible involvement of brain-derived neurotrophic factor in the antinociceptive effect of antidepressants in neuropathic pain Fulltext Access 4 Pages 2005
The case for dietary calcium restriction in patients with atherosclerosis Fulltext Access 4 Pages 2005
Combining transfusion of stem/progenitor cells into the peripheral circulation with localized transplantation in situ at the site of tissue/organ damage: A possible strategy to optimize the efficacy of stem cell transplantation therapy Fulltext Access 4 Pages 2005
Bilinear model for the prediction of drug solubility in ethanol/water mixtures Fulltext Access 4 Pages 2005
Hypothesis: A motor neuron toxin produced by a clostridial species residing in gut causes ALS Fulltext Access 4 Pages 2005
Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents Fulltext Access 4 Pages 2005
Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains Fulltext Access 4 Pages 2005
Synthesis of substituted indole derivatives as a new class of antimalarial agents Fulltext Access 4 Pages 2005
Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists Fulltext Access 4 Pages 2005
Synthesis and characterization of the monomer ruthenium complex of hypocrellin B Fulltext Access 4 Pages 2005
Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics Fulltext Access 4 Pages 2005
The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: Antagonists versus agonists Fulltext Access 4 Pages 2005
Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs Fulltext Access 4 Pages 2005
Supportive neurodevelopmental evidence for ADHD as a developmental disorder Fulltext Access 4 Pages 2005
Synthesis and antibacterial activity of some 5-(4-biphenylyl)-7-aryl[3,4-d] [1,2,3]-benzothiadiazoles Fulltext Access 4 Pages 2005
Synthesis of 4-aryl-7,7-dimethyl-1,2,3,4,5,6,7,8-octahydroquinazoline-2-one/thione-5-one derivatives and evaluation as antibacterials Fulltext Access 4 Pages 2005
Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid Fulltext Access 4 Pages 2005
Antiproliferative activities of iron and platinum conjugates of salicylaldehyde semi-/thiosemicarbazones against C6 glioma cells Fulltext Access 4 Pages 2005
Synthesis, anti-HIV and antitubercular activities of lamivudine prodrugs Fulltext Access 4 Pages 2005
Synthesis and chemiluminescent high throughput screening for inhibition of acetylcholinesterase activity by imidazo[2,1-b]thiazole derivatives Fulltext Access 4 Pages 2005
Elimination of major side effects due to ROS of therapeuticals through biotransformation control of the 57 cytochromes P450 isoenzymes Fulltext Access 4 Pages 2005
Charming the mosquito: do malaria symptoms increase the attractiveness of the host for the vector? Fulltext Access 4 Pages 2005
Matrix metalloproteinases synthesized in autosomal dominant polycystic kidney disease play a role in development of a concurrent abdominal aortic aneurysm Fulltext Access 4 Pages 2005
Is the liver an important site for the development of immune tolerance to tumours? Fulltext Access 4 Pages 2005
The empirical relationship between longevity and physical stature may be obscured by unobserved genetic diversity in the optimal metabolic rate Fulltext Access 4 Pages 2005
High mitochondrial redox potential may promote induction and activation of UCP2 in hepatocytes during hepatothermic therapy Fulltext Access 4 Pages 2005
The influence of weather and environment on pulmonary embolism: pollutants and fossil fuels Fulltext Access 4 Pages 2005
Primary nocturnal enuresis: omega-3 fatty acids may be of therapeutic value Fulltext Access 4 Pages 2005
Significant reduction of the risk of venous thromboembolism in all long term immobile patients a few months after the onset of immobility Fulltext Access 4 Pages 2005
Reconstruction of the anterior cruciate ligament with a Patella-Tendon-Bone graft may lead to a permanent loss of bone mineral content due to decreased patellar tendon stiffness Fulltext Access 4 Pages 2005
Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients Fulltext Access 4 Pages 2005
Design, synthesis and structure-activity relationship of a series of fragment analogues of antistasin (ATS) and ghilantens (GLS) Fulltext Access 4 Pages 2005
Characterisation and biodistribution of two neutral 99mTc(CO)3 complexes with a tridentate ligand Fulltext Access 4 Pages 2005
Isolation, structure elucidation, preparation, and biological properties of neolambertellin Fulltext Access 4 Pages 2005
SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors Fulltext Access 4 Pages 2005
Camptothecin binds to a synthetic peptide identified by a T7 phage display screen Fulltext Access 4 Pages 2005
Synthesis of a biotinylated camptothecin derivative and determination of the binding sequence by T7 phage display technology Fulltext Access 4 Pages 2005
Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases Fulltext Access 4 Pages 2005
Investigation of factor Xa inhibitors containing non-amidine S1 elements Fulltext Access 4 Pages 2005
A fluorogenic and chromogenic probe that detects the esterase activity of trace copper(II) Fulltext Access 4 Pages 2005
Novel indole α-methylene-γ-lactones as potent inhibitors for AKT-mTOR signaling pathway kinases Fulltext Access 4 Pages 2005
Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors Fulltext Access 4 Pages 2005
5-Substituted 4-anilinoquinazolines as potent, selective and orally active inhibitors of erbB2 receptor tyrosine kinase Fulltext Access 4 Pages 2005
New fluorinated pyrrolidine and azetidine amides as dipeptidyl peptidase IV inhibitors Fulltext Access 4 Pages 2005
Potential antitumor agents: Flavones and their derivatives from Linaria reflexa Desf. Fulltext Access 4 Pages 2005
High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor Fulltext Access 4 Pages 2005
Benzyl ether structure–activity relationships in a series of ketopiperazine-based renin inhibitors Fulltext Access 4 Pages 2005
Synthesis of 4-(5-[18F]fluoromethyl-3-phenylisoxazol-4-yl)benzenesulfonamide, a new [18F]fluorinated analogue of valdecoxib, as a potential radiotracer for imaging cyclooxygenase-2 with positron emission tomography Fulltext Access 4 Pages 2005
Inhibition of Src kinase activity by 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-heteroaryl-thieno[3,2-b]pyridine-6-carbonitriles Fulltext Access 4 Pages 2005
Synthesis of linked berberine dimers and their remarkably enhanced DNA-binding affinities Fulltext Access 4 Pages 2005
Molecular design, chemical synthesis, and evaluation of cytosine–carbohydrate hybrids for selective recognition of a single guanine bulged duplex DNA Fulltext Access 4 Pages 2005
Synthesis and antibacterial activity of novel (un)substituted benzotriazolyl oxazolidinone derivatives Fulltext Access 4 Pages 2005
4-Substituted (benzo[b]thiophene-2-carbonyl)guanidines as novel Na+/H+ exchanger isoform-1 (NHE-1) inhibitors Fulltext Access 4 Pages 2005
Three-dimensional structure of Plasmodium falciparum Ca2+-ATPase(PfATP6) and docking of artemisinin derivatives to PfATP6 Fulltext Access 4 Pages 2005
New piperidinyl- and 1,2,3,6-tetrahydropyridinyl-pyrimidine derivatives as selective 5-HT1A receptor agonists with highly potent anti-ischemic effects Fulltext Access 4 Pages 2005
Structure-activity relationships of novel endomorphin-2 analogues with N-O turns induced by α-aminoxy acids Fulltext Access 4 Pages 2005
Non-hydroxamate 5-phenylpyrimidine-2,4,6-trione derivatives as selective inhibitors of tumor necrosis factor-α converting enzyme Fulltext Access 4 Pages 2005
Synthetic lanostane-type triterpenoids as inhibitors of DNA topoisomerase II Fulltext Access 4 Pages 2005
DNA binding specificity and cytotoxicity of novel antitumor agent Ge132 derivatives Fulltext Access 4 Pages 2005
Epibatidine analogues as selective ligands for the αxβ2-containing subtypes of nicotinic acetylcholine receptors Fulltext Access 4 Pages 2005
Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor Fulltext Access 4 Pages 2005
Adamantyl triazoles as selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 Fulltext Access 4 Pages 2005
Dipyridyl amines: Potent metabotropic glutamate subtype 5 receptor antagonists Fulltext Access 4 Pages 2005
A new synthesis of isoaurones: Cytotoxic activity of compounds related to the alleged structure of isoaurostatin Fulltext Access 4 Pages 2005
Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies Fulltext Access 4 Pages 2005
Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents Fulltext Access 4 Pages 2005
Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1β synthesis Fulltext Access 4 Pages 2005
A general method for the synthesis of aryl [11C]methylsulfones: Potential PET probes for imaging cyclooxygenase-2 expression Fulltext Access 4 Pages 2005
Reactions of α-hydroxyethyl radicals with flavonoids of various structures Fulltext Access 4 Pages 2005
Design and synthesis of a novel peptidomimetic inhibitor of HIV-1 Tat–TAR interactions: Squaryldiamide as a new potential bioisostere of unsubstituted guanidine Fulltext Access 4 Pages 2005
Synthesis and structure–activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7 Fulltext Access 4 Pages 2005
Structure–activity relationships of Erwinia carotovora quorum sensing signaling molecules Fulltext Access 4 Pages 2005