Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators Fulltext Access 29 Pages 2006
A Multiphase Microscopic Diffusion Model for Stratum Corneum permeability. I. Formulation, Solution, and Illustrative Results for Representative Compounds Fulltext Access 29 Pages 2006
Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists Fulltext Access 30 Pages 2006
Hydrogels in controlled release formulations: Network design and mathematical modeling Fulltext Access 30 Pages 2006
In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery Fulltext Access 31 Pages 2006
Conceptualizing and measuring pharmacist-patient communication: a review of published studies Fulltext Access 33 Pages 2006
Display technologies: Application for the discovery of drug and gene delivery agents Fulltext Access 33 Pages 2006
Recent advances in iron oxide nanocrystal technology for medical imaging Fulltext Access 34 Pages 2006
Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites Fulltext Access 40 Pages 2006
Oral treatment options for degenerative joint disease—presence and future Fulltext Access 44 Pages 2006
Mathematical modeling and simulation of drug release from microspheres: Implications to drug delivery systems Fulltext Access 52 Pages 2006
The influence of formulation variables on stability and microbicidal activity of monoglyceride monocaprin Fulltext Access 4 Pages 2005
Photoinduced antitumour effect of hypericin can be enhanced by fractionated dosing Fulltext Access 4 Pages 2005
Effect on prolactin secretion of Echinacea purpurea, Hypericum perforatum and Eleutherococcus senticosus Fulltext Access 4 Pages 2005
Structure-antimicrobial activity of some natural isocoumarins and their analogues Fulltext Access 4 Pages 2005
Effect of the aqueous extract of Hyptis pectinata on liver mitochondrial respiration Fulltext Access 4 Pages 2005
Screening for antiproliferative activity of six southern Brazilian species of Hypericum Fulltext Access 4 Pages 2005
1,3-dihydroxy-5-(tridec-4â²,7â²-dienyl)benzene: a new cytotoxic compound from Lithraea molleoides Fulltext Access 4 Pages 2005
Antimicrobial activity of isoprenoid-substituted xanthones from Cudrania cochinchinensis against vancomycin-resistant enterococci Fulltext Access 4 Pages 2005
Temporal variation of chemical composition and relaxant action of the essential oil of Ocimum gratissimum L. (Labiatae) on guinea-pig ileum Fulltext Access 4 Pages 2005
Design and optimization of ocular inserts for prolonged delivery of ciprofloxacin hydrochloride Fulltext Access 4 Pages 2005
Particle release and surface characteristics of polyvinylchloride perfusional containers after steam sterilization Fulltext Access 4 Pages 2005
Effect of physical properties of carrier particles on drug emission from a dry powder inhaler device Fulltext Access 4 Pages 2005
A comparison of high speed differential scanning calorimetry (Hyper-DSC) and modulated differential scanning calorimetry to detect the glass transition of polyvinylpyrrolidone: the effect of water content and detection sensitivity in powder mixtures (a mo Fulltext Access 4 Pages 2005
In situ forming lyotropic liquid crystalline systems containing metronidazole-benzoate Fulltext Access 4 Pages 2005
Transcription efficiency of tamoxifen citrate-loaded β-cyclodextrin nanoparticles Fulltext Access 4 Pages 2005
Synthesis and comparative skin permeability of atenolol and propranolol esters Fulltext Access 4 Pages 2005
Inclusion of methotrexate in alkyl-cyclodextrins: effects of host substitutents on the stability of complexes Fulltext Access 4 Pages 2005
Measurement of surface glass transition temperature of amorphous cefditoren pivoxil granules by inverse gas chromatography Fulltext Access 4 Pages 2005
The use of microviscometry to study polymer dissolution from solid dispersion drug delivery systems Fulltext Access 4 Pages 2005
Effect of Vitamin E TPGS on immune response to nasally delivered diphtheria toxoid loaded poly(caprolactone) microparticles Fulltext Access 4 Pages 2005
Stability of latanoprost in an ophthalmic lipid emulsion using polyvinyl alcohol Fulltext Access 4 Pages 2005
Correlation between the release characteristics of theophylline and the free volume of polyvinylpyrrolidone Fulltext Access 4 Pages 2005
Establishment of an in vitro model expressing the folate receptor for the investigation of targeted delivery systems Fulltext Access 4 Pages 2005
The birth of Research in Social & Administrative Pharmacy: a sincere welcome to subscribers, readers, and authors Fulltext Access 4 Pages 2005
The interaction of direct-to-consumer prescription drug advertising and stakeholders in the medication use process Fulltext Access 4 Pages 2005
Animal models and their limitations: On the problem of high-to-low dose extrapolations following inhalation exposures Fulltext Access 4 Pages 2005
Aminoalkoxybenzyl pyrrolidines as novel human urotensin-II receptor antagonists Fulltext Access 4 Pages 2005
Synthesis and antibacterial activity of 5-methoxy- and 5-hydroxy-6-fluoro-1,8-naphthyridone-3-carboxylic acid derivatives Fulltext Access 4 Pages 2005
Redox-responsive and calcium-dependent switching of glycosyldisulfide interactions with Concanavalin A Fulltext Access 4 Pages 2005
Discovery and synthesis of a novel and selective drug-like P2X1 antagonist Fulltext Access 4 Pages 2005
Synthesis of (1,4)-naphthoquinono-[3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives as antifungal, antibacterial, and anticancer agents Fulltext Access 4 Pages 2005
Metabolism investigation leading to novel drug design: Orally active prostacyclin mimetics. Part 4 Fulltext Access 4 Pages 2005
Synthesis and biological evaluation of novel bisphosphonates with dual activities on bone in vitro Fulltext Access 4 Pages 2005
6-(2-Phenylethyl)nicotine: A novel nicotinic cholinergic receptor ligand Fulltext Access 4 Pages 2005
Synthesis and antitumor activity of the hexacyclic camptothecin derivatives Fulltext Access 4 Pages 2005
Chiral discrimination in binding of enantiomers of 2-(aminoalkoxy)-substituted 4-(2-thienyl)pyrimidines and 4,6-bis(2-thienyl)pyrimidines with duplex DNA Fulltext Access 4 Pages 2005
Action of a novel pyrrolo[1,2-c][1.3]benzodiazepine on the viability of Jurkat and neuronal/glial cells Fulltext Access 4 Pages 2005
Pharmacophore-based design, synthesis, biological evaluation, and 3D-QSAR studies of aryl-piperazines as α1-adrenoceptor antagonists Fulltext Access 4 Pages 2005
Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists Fulltext Access 4 Pages 2005
Water soluble prodrug of a COX-2 selective inhibitor suitable for intravenous administration in models of cerebral ischemia Fulltext Access 4 Pages 2005
A three-residue, continuous binding epitope peptidomimetic of ShK toxin as a Kv1.3 inhibitor Fulltext Access 4 Pages 2005
Investigation of human serum albumin (HSA) binding specificity of certain photosensitizers related to pyropheophorbide-a and bacteriopurpurinimide by circular dichroism spectroscopy and its correlation with in vivo photosensitizing efficacy Fulltext Access 4 Pages 2005
Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases Fulltext Access 4 Pages 2005
New series of potent δ-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif Fulltext Access 4 Pages 2005
Anti-malarial activity of Baylis–Hillman adducts from substituted 2-chloronicotinaldehydes Fulltext Access 4 Pages 2005
Conformationally restricted analogs of Combretastatin A-4 derived from SU5416 Fulltext Access 4 Pages 2005
Bilinear model for the prediction of drug solubility in ethanol/water mixtures Fulltext Access 4 Pages 2005
Iontophoretic Transdermal Delivery of Sumatriptan: Effect of Current Density and Ionic Strength Fulltext Access 4 Pages 2005
Efficient synthesis of C-terminal modified peptide ketones for chemical ligations Fulltext Access 4 Pages 2005
New heterocyclic analogues of 4-(2-chloro-5-methoxyanilino)quinazolines as potent and selective c-Src kinase inhibitors Fulltext Access 4 Pages 2005
A thiolate ligand on a cytochrome P-450 mimic permits the use of simple environmentally benign oxidants for biomimetic steroid hydroxylation in water Fulltext Access 4 Pages 2005
The inhibitory effect of glutathione on buccal enzymatic degradation of therapeutic peptides (leu-enkephalin, luteinizing hormone-releasing hormone and pituitary adenylate cyclase activating peptide) Fulltext Access 4 Pages 2005
Azinomycin inspired bisepoxides: influence of linker structure on in vitro cytotoxicity and DNA interstrand cross-linking Fulltext Access 4 Pages 2005
Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors Fulltext Access 4 Pages 2005
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13 Fulltext Access 4 Pages 2005
A micromethod for the stereochemical analysis of fatty acid desaturase-mediated sulfoxidation reactions Fulltext Access 4 Pages 2005
The evaluation of 2,8-disubstituted benzoxazinone derivatives as anti-inflammatory and anti-platelet aggregation agents Fulltext Access 4 Pages 2005
Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants Fulltext Access 4 Pages 2005
Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase Fulltext Access 4 Pages 2005