دانلود مقالات ISI درباره App + ترجمه فارسی

Research ReportSomatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ42 oligomers via a metalloproteinase-dependent mechanism

Keywords: Aβ; amyloid protein; SSTR; somatostatin receptor subtype; APP; amyloid precursor protein; AD; Alzheimer's disease; Phosphoramidon; NNC 26-9100; Somatostatin receptor subtype-4; Amyloid-beta oligomer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Amyloid β precursor protein as a molecular target for amyloid β-induced neuronal degeneration in Alzheimer's disease

Keywords: APP; Alzheimer's disease; Aβ; Neuritic dystrophy; Synaptic degeneration; Dying-back degeneration;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Potential therapeutic applications of differentiated induced pluripotent stem cells (iPSCs) in the treatment of neurodegenerative diseases

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic Lateral Sclerosis; APP; amyloid precursor protein; BDNF; brain-derived neurotrophic factor; BM-MSCs; bone marrow-derived MSCs; DNA; deoxyribonucleic acid; EBs; embryoid bodies; ESC; embryonic st

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

Keywords: Aβ; amyloid peptide; AD; Alzheimer's disease; APP; β-amyloid precursor protein; COX-2; cyclooxygenase-2; EGCG; (−)-epigallocatechin-3-gallate; GAPDH; glyceraldehydes-3-phosphate dehydrogenase; ICAM-1; intercellular adhesion molecule-1; icv; intracereb

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Progress in microRNA delivery

Keywords: AMO; anti-miRNA oligonucleotides; APP; amyloid precursor protein; BBB; blood-brain barrier; bp; base pairs; CNS; central nervous system; CSC; cancer stem cell; DDAB; dimethyldioctadecylammonium bromide; DGCR8; DiGeorge syndrome critical region gene; DNA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Prevention of β-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events

Keywords: iPS cells; induced pluripotent stem cells; hiPS-C4; hiPS cell line UC C0406 iPS-C4; ES cells; embryonic stem cells; NPCs; neural progenitor cells; CCEs; cell cycle events; Aβ; β-amyloid; NFTs; neurofibrillary tangles; APP; amyloid precursor protein; AD;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy, polyphenols and healthy ageing

Keywords: AD; Alzheimer's disease; AMP; adenosine monophosphate; AMPK; adenosine monophosphate activated protein kinase; APP; amyloid beta precursor protein; Atg; autophagy (related gene); ATP; adenosine triphosphate; AV; autophagic vacuoles; Aβ; amyloid beta; Bcl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases

Keywords: LXR; Oxysterols; Dementia; Biomarker; Mass spectrometry; 24OHC; 24S-hydroxycholesterol; 27OHC; 27-hydroxycholesterol; Aβ; amyloid beta; ABC; ATP-binding cassette transporter; ACAT; acyl-Coa:cholesterol acyltransferase; AD; Alzheimer disease; Apoe; apolip

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Tau protein kinases: Involvement in Alzheimer's disease

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Arg; Abl-related gene; SFK; Src family kinase; Aβ; β-amyloid; BBB; blood brain barrier; LD50; lethal dose 50; c-Abl; c-Abelson; Cables; c-Abl-binding adaptator protein; CaMKII; Ca2+/calmodulin-dep

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2013 سفارش ترجمه

Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: A proteomics study

Keywords: AD; Alzheimer's disease; MCI; mild cognitive impairment; Aβ; amyloid β-peptide; FAD; familial Alzheimer's disease; NFT; intracellular neurofibrillary tangles; APP; amyloid precursor protein; PS-1; presenilin-1; PS-2; presenilin-2; AO; antisense oligonuc

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2013 سفارش ترجمه

Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons

Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; EGCG; (−)-epigallocatechin-3-gallate; BAG2; BCL2-associated athanogene 2; LAMP1; lysosomal-associated membrane protein 1; NFTs; neurofibillary tangles; BACE1; beta-site APP cleaving enzyme-1; APP; amyloid prec

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Chitosan oligosaccharides protect rat primary hippocampal neurons from oligomeric β-amyloid 1-42-induced neurotoxicity

Keywords: AD; Alzheimer's disease; Aβ; β-amyloid peptide; APP; amyloid precursor protein; SPs; senile plaques; NFTs; neurofibrillary tangles; ROS; reactive oxygen species; COSs; chitosan oligosaccharides; Aβ42; β-amyloid fragments 1-42; HFIP; 1,1,1,3,3,3-hexafl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Endovascular Treatment of Juxta-anastomotic Venous Stenoses of Forearm Radiocephalic Fistulas: Long-term Results and Prognostic Factors

Keywords: APP; assisted primary patency; AVF; arteriovenous fistula; FEI; frequency of endovascular intervention; JAS; juxta-anastomotic stenosis; PP; primary patency;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Development of an app for estimating leaf area index using a smartphone. Trueness and precision determination and comparison with other indirect methods

Keywords: Leaf area index; LAI-2000; AccuPAR; app; Smartphone; Accuracy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Abdominal Compartment Syndrome: A Decade of Progress

Keywords: ACS; abdominal compartment syndrome; APP; abdominal perfusion pressure; BMI; body mass index; IAH; intra-abdominal hypertension; IAP; intra-abdominal pressure; ICP; intracranial pressure; RVEDVI; right ventricular end diastolic volume index;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

A fast growing spectrum of biological functions of γ-secretase in development and disease

Keywords: γ-Secretase, regulated intramembrane proteolysis; Presenilin; APP; Notch; Alzheimer

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Nuclear α1-Antichymotrypsin Promotes Chromatin Condensation and Inhibits Proliferation of Human Hepatocellular Carcinoma Cells

Keywords: Liver Cancer; Nuclear Factor; Mouse Model; DNA Binding; AAV; adeno-associated virus; α1-ACT; antichymotrypsin; APP; acute-phase protein; APR; acute-phase response; DOX; doxycycline; EGF; epidermal growth factor; HCC; hepatocellular carcinoma; MENT; myelo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

The leucine-rich repeats of LINGO-1 are not required for self-interaction or interaction with the amyloid precursor protein

Keywords: APP; amyloid precursor protein; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; IgI1; immunoglobulin domain; LINGO-1; leucine rich repeat and Ig domain containing Nogo receptor interacting protein-1; LRR; leucine rich repeat;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewThe role of Nogo-A in neuroregeneration: A review

Keywords: Nogo A; Nogo-66 receptor; Neuroregeneration; Spinal cord injury; Animal models; CNS; central nervous system; NgR; Nogo-66 receptor; GPI; glycosylphosphatidylinositol; MAG; myelin associate glycoprotein; AD; Alzheimer's disease; APP; amyloid precursor prot

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The γ-secretase inhibitor DAPT increases the levels of gangliosides at neuritic terminals of differentiating PC12 cells

Keywords: Aβ; amyloidβ-peptide; AD; Alzheimer disease; APP; β-amyloid precursor protein; ESI; electrospray ionization; GAβ; ganglioside-bound Aβ; LC; liquid chromatography; MRM; multiple reaction monitoring; MS; mass spectrometry; MS/MS; tandem mass spectromet

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Anesthesia Apps: Overview of Current Technology and Intelligent Search Techniques

Keywords: app; medical app; iPhone; smartphone; anesthesia app; Google; Android; Blackberry; Objective-c; programming; informatics; medical applications; medical computer applications; medical software; search for anesthesia apps; anesthesia calculator; anesthesia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Active Aβ vaccination fails to enhance amyloid clearance in a mouse model of Alzheimer's disease with Aβ42-driven pathology

Keywords: AD; Alzheimer's disease; Aβ; amyloid beta-peptide; CNS; central nervous system; APP; amyloid precursor protein; CFA; complete Freund's adjuvant; FAD; familial Alzheimer's disease; HLA; human leukocyte antigen; IFA; incomplete Freund's adjuvant; PS1; pres

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

MicroRNAs in Alzheimer's disease

Keywords: Alzheimer's disease; MicroRNA; Non-coding RNA; APP; BACE1; Tau;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research reportMicroRNA-195 downregulates Alzheimer's disease amyloid-β production by targeting BACE1

Keywords: AD; Alzheimer's disease; Aβ; amyloid-beta; NFTs; neurofibrillary tangles; APP; amyloid precursor protein; sAPPβ; the secreted beta-form of APP; Aβ; amyloid-beta; BACE1; beta-site APP cleaving enzyme 1; 3′-UTR; 3′-untranslated region; sAPPβ; the se

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Biophysical studies with AICD-47 reveal unique binding behavior characteristic of an unfolded domain

Keywords: APP; amyloid precursor's protein; AICD; APP-intracellular C-terminal domain; AD; Alzheimer's disease; SH2; Src homology 2; PTR and pY; phosphorylated tyrosine; IUD; intrinsically unstructured domain; Grb2; growth factor receptor binding protein 2, TFE

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer's Disease patients

Keywords: AD; Alzheimer's Disease; APOE; apolipoprotein E; APP; amyloid precursor protein; bp; base pair; CDR; clinical dementia rating; CT; cycle threshold; df; degrees of freedom; DSM-IV; IV Diagnostic and Statistical Manual of Mental Disorders; F; female; GLM;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Cognitive phenotyping of amyloid precursor protein transgenic J20 mice

Keywords: Alzheimer's disease; Transgenic mouse model; J20; APP; Learning and memory

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

M1 muscarinic acetylcholine receptor interacts with BACE1 and regulates its proteosomal degradation

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; APP; β-amyloid precursor protein; BACE1; β-site APP cleaving protein 1; HEK-APPSwe; HEK cells stably expressing human APP Swedish mutations; M1 mAChR; M1 muscarinic acetylcholine receptor; mAChRs; muscarinic ace

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

NMDA receptor/amyloid precursor protein interactions: A comparison between wild-type and amyloid precursor protein mutations associated with familial Alzheimer's disease

Keywords: Aβ; amyloid-β peptides; apoEr2; apolipoprotein E receptor 2; APP; amyloid precursor protein; ELISA; enzyme linked immunoadsorbent assay; NMDA; N-methyl-d-aspartate; NR1; NR2A, etc.NMDA receptor NR1 subunit, NR2A subunit, etc.; PBS; phosphate buffered; P

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment

Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid β-peptide; TM; transmembrane; JM; juxtamembrane; APPjmtm; APP686-726 fragment; DPC; dodecylphosphocholine; NOE; nuclear overhauser effect; NOESY; NOE spectroscopy; HSQC; heteronucl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury

Keywords: TBI; traumatic brain injury; TAI; traumatic axonal injury; rcTBI; repetitive closed-skull TBI; APP; amyloid precursor protein; DTI; diffusion tensor imaging; RA; relative anisotropy; RD; radial diffusivity; AD; axial diffusivity; MD; mean diffusivity; Dif

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort

Keywords: Alzheimer's disease; Mutations; Serbia; Presenilins; APP;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Actions of the Kunitz-type serine protease inhibitor Amblyomin-X on VEGF-A-induced angiogenesis

Keywords: Amblyomma cajennense; Chorioallantoic membrane; Dorsal skinfold chamber; Intravital microscopy; PECAM-1; t-End endothelial cell; APP; Alzheimer's amyloid precursor protein; Ambly; Amblyomin-X; CFSE; Carboxyfluorescein diacetate succinimidyl ester; CAM; Ch

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

BACE1 in Alzheimer's disease

Keywords: Aβ; β-amyloid; ACDL; acid-cluster dileucine motif; AD; Alzheimer's disease; ADAM; a disintegrin and metalloprotease domain protein; AICD; amyloid precursor protein intracellular domain; APLP; amyloid precursor-like protein; ApoE; apolipoprotein E; APP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Neuroprotection by the multitarget iron chelator M30 on age-related alterations in mice

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; DFO; defferoxamine; DA; dopamine; MAO; monoamine oxidase; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; OS; Oxidative stress; PD; Parkinson's disease; PSEN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Scaffold protein Homer 1: Implications for neurological diseases

Keywords: EVH1; Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) homology 1; IEG; immediate-early gene; P motif; proline-containing motif; mGluR; metabotropic glutamate receptor; IP3R; inositol 1,4,5-trisphosphate receptor; TRPC; transient receptor potentia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperSimilar pattern of peripheral neuropathy in mouse models of type 1 diabetes and Alzheimer's disease

Keywords: Alzheimer's disease; amyloid precursor protein; diabetes; insulin signaling; sciatic nerve; diabetic neuropathy; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid β; EDTA; ethylenediaminetetraacetic acid; FL-APP; full-length APP; GSK3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Biochemical label-free tissue imaging with subcellular-resolution synchrotron FTIR with focal plane array detector

Keywords: Aβ; amyloid beta; AD; Alzheimer disease; APP; amyloid protein precursor; CA; cornu ammonis; CH2; methylene group; CNS; central nervous system; DG; dentate gyrus; DHA; docosahexaenoic acid; FPA; focal plane array; FTIR; Fourier transform infrared spectros

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

miR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression

Keywords: ABCA1; ATP-binding cassette transporter A1; AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; ApoA-I; apolipoprotein A1; ApoE; apolipoprotein E; BACE1; β-site APP-cleaving enzyme1; CTFβ; C-terminal fragment β; HDL; high-density

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Redox-active Cu(II)-Aβ causes substantial changes in axonal integrity in cultured cortical neurons in an oxidative-stress dependent manner

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; APP; β-amyloid precursor peptide; DIV; days in vitro; MT; metallothionein; ROS; reactive oxygen species; Neurodegeneration; Beta-amyloid; Neurotoxicity; Oxidative stress; Axon degeneration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Protective effects of astragalosides on dexamethasone and Aβ25-35 induced learning and memory impairments due to decrease amyloid precursor protein expression in 12-month male rats

Keywords: Dexamethasone; Aβ25-35; Memory and learning impairment; APP; Astragalosides;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The combined effect of organic phoshphinate/ammonium polyphosphate and pentaerythritol on thermal and fire properties of polyamide 6-clay nanocomposites

Keywords: PA6; Organoclay; Organic phosphinate; APP; Melt blending; Cone calorimetry;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Dexamethasone and Aβ25–35 accelerate learning and memory impairments due to elevate amyloid precursor protein expression and neuronal apoptosis in 12-month male rats

Keywords: Memory and learning impairment; Dexamethasone; APP; Apoptosis; AD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series

Keywords: APP; Duplication; PRNP; Prion; Chromosome 21; Dementia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Pro-oxidant diet enhances β/γ secretase-mediated APP processing in APP/PS1 transgenic mice

Keywords: Oxidative stress; APP; Alzheimer's disease; TASTPM mice; BACE; presenilin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AKT; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor; aPKC; atypical protein kinase C; APP; amyloid-β precursor protein; ATG; AuTophaGy-related; BDNF; brain-derived neurotrophic factor; C/EBP; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Pyrrolidine dithiocarbamate attenuates brain Aβ increase and improves long-term neurological outcome in rats after transient focal brain ischemia

Keywords: Aβ; β-amyloid peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; BACE1; β-secretase/β-amyloid converting enzyme 1; Fr1; frontal cortex area 1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; IDE; insulin-degrading enzyme; MCAO; middle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease

Keywords: 2N; normal disomic littermates; AD; Alzheimer's disease; Aβ; amyloid-β peptide; APP; amyloid-β precursor protein; ANOVA; analysis of variance; ApoE; apolipoprotein E; CH; calcium and potassium channels; CBF; cholinergic basal forebrain; Ct; cycle thres

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Conformational analysis of amyloid precursor protein fragment containing amino acids 667–676, and the effect of d-Asp and iso-Asp substitution at Asp672 residue

Keywords: Amyloid; APP; Peptide; TFE; Circular dichroism; d-Amino acid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

JD-30, an active fraction extracted from Danggui-Shaoyao-San, decreases β-amyloid content and deposition, improves LTP reduction and prevents spatial cognition impairment in SAMP8 mice

Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid protein precursor; BACE1; beta-site amyloid cleave enzyme-1; CatB; cathepsin B; DG; dentate gyrus; DSS; Danggui-Shaoyao-San; GAPDH; glyceraldehyde phosphate dehydrogenase; HFS; high frequency stim

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه