دانلود مقالات ISI درباره Ec50 + ترجمه فارسی

Enhancement of antibody fragment secretion into the Escherichia coli periplasm by co-expression with the peptidyl prolyl isomerase, FkpA, in the cytoplasm

Keywords: Fab; fragment-antigen-binding; Fc; fragment crystallizable; Fd; fragment of antibody consisting of CH1 and VH; ScFv; single-chain variable fragment; VH; variable heavy; VL; variable light; PPIase; peptidyl prolyl cis-trans isomerase; PCR; polymerase chain

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors

Keywords: AOP; adverse outcome pathway; hCAR; human constitutive androstane receptor; mCAR; mouse constitutive androstane receptor; rCAR; rat constitutive androstane receptor; cDNA; complementary DNA; CITCO; 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldeh

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

P2X7 receptors at adult neural progenitor cells of the mouse subventricular zone

Keywords: Adult neural progenitor cells; Brain subventricular zone; P2X7 receptors; Extracellular ATP; α,β-meATP; α,β-methylene ATP; 5-BDBD; 5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one; BBG; Brilliant Blue G; Bz-ATP; 2′(3′)-O-(4-ben

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation

Keywords: Asthma; viral respiratory tract infections; glucocorticoids; transcription factors; kinases; EC50; Median effective concentration; Emax; Maximal effective concentration; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GR; Glucocorticoid receptor; GRE; Gl

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function

Keywords: α-CtxMII; α-conotoxin MII; CX; Cortex; CX, il; Cortex,inner layers; CX,ol; Cortex,outer layers; DLG; Dorsolateral geniculate; GP; Globus pallidus; HP; Hippocampus; IC; Inferior colliculus; IC, dc; Inferior colliculus,dorsal cortex; IPN; Interpeduncular

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Antispasmodic effects and composition of the essential oils from two South American chemotypes of Lippia alba

Keywords: CRC; concentration-response curve; CEO; citral chemotype essential oil; EO; essential oil; LEO; linalool chemotype essential oil; ACh; acethylcholine; IC50; inhibitory concentration to 50%; EC50; effective concentration at 50%; GC-FID-MS; gas chromatogr

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons

Keywords: HCV; hepatic C virus; GT; genotype; NS; non-structural; DAA; direct-acting antivirals; 2-CMeA; 2-C-methyl adenosine; CsA; cyclosporin A; Rluc; Renilla luciferase; RLU; relative light units; neo; neomycin transferase gene; G418; geneticin; EC50; 50% effect

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2013 سفارش ترجمه

Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice

Keywords: Acta1; α-skeletal actin gene or mRNA; Atp2a2; ATPase, Ca2 + transporting, cardiac mRNA; BPM; Beats per minute; cMyBP-C; Cardiac myosin-binding protein C; EC50; Half maximal effective concentration; EHT; Engineered heart tissue; EMD; EMD 57033; HCM; Hype

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2013 سفارش ترجمه

Effect of pH on the toxicity and bioconcentration of sulfadiazine on Daphnia magna

Keywords: Sulfonamide; Speciation; Crustacean; EC50; Bioconcentration

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Physiological and biochemical responses of the marine dinoflagellate Prorocentrum minimum exposed to the oxidizing biocide chlorine

Keywords: Oxidizing biocide; Prorocentrum minimum; Chlorine; EC50; Growth rate; Chlorophyll autofluorescence; Antioxidant enzyme activity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Physiological and molecular characterization of Phytophthora infestans isolates from the Central Colombian Andean Region

Keywords: EC50; Molecular diversity; Mefenoxam sensitivity; Curzate; Oospores; Ridomil gold; Avr3a; β-tubulin; Races; RxLR motif; EC50; Diversidad molecular; Sensibilidad al mefenoxam; Curzate; Oosporas; Ridomil gold; Avr3a; β-tubulin; Razas; Motivo RxLR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Life-history effects of arsenic toxicity in clades of the earthworm Lumbricus rubellus

Keywords: Population growth rate; EC50; Genotype; Bioaccumulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Ecological screening indicators of stress and risk for the Llobregat river water

Keywords: ACA; Catalan Water Agency; AF; assessment factor; BCF; bioconcentration factor; CI; confidence interval; DWTP; drinking water treatment plant; DGT; diffusive gradient thin film; EC50; term half maximal effective concentration; ERA; ecological risk assessm

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

The relevance of chemical interactions with CYP17 enzyme activity: Assessment using a novel in vitro assay

Keywords: 4-OH-ASDN; 4-hydroxyandrostenedione; cAMP; cyclic AMP; ATZ; atrazine; BPA; bisphenol A; CSA; cyclosporin A; CYP11A; cytochrome P450 11A; CYP17; cytochrome P450 17; CYP19 (aromatase); cytochrome P450 19; DBP; dibutyl phthalate; DEHP; diethylhexyl phthalate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Major furocoumarins in grapefruit juice II: Phototoxicity, photogenotoxicity, and inhibitory potency vs. cytochrome P450 3A4 activity

Keywords: CYP; cytochrome P450; DHB; 6′,7′-dihydroxybergamottin; EC50; effective concentration 50%; HPRT; hypoxanthine-guanine phosphoribosyl transferase; 5-MOP; 5-methoxypsoralen; PMEF; photomutagenicity equivalency factor; PMIEF; Photo-Micronucleus Inductio

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Antioxidant activity of propolis extracts from Serbia: A polarographic approach

Keywords: ANOVA; analysis of variance; AO; antioxidant activity; BHT; butylated hydroxytoluene; CL; Clarc and Lubs; i-E; current-potential; DPPH; 1,1-diphenyl-2-picryl hydrazyl; DC; direct current; DME; dropping mercury electrode; EC50; efficient concentration;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

What are the optimal pharmacokinetic properties of antipsychotic medications?

Keywords: [D]; molar concentration of antipsychotics in the extracellular fluid; D2R; dopamine D2 receptor; D2H; high-affinity D2R; D2L; low-affinity D2R; EC50; half-maximal effective concentration; Kd; dissociation constant of dopamine for D2R; Ki; dissociation co

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506

Keywords: EC50; 50% effective inhibitory concentration; RLU; relative light units; SARS-CoV; HCoV-NL63; HCoV-229E; FK506; Tacrolimus; Immunophilins; FKBP1A (FKBP12); FKBP1B (FKBP12.6); Inhibition of viral replication;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Antimicrobial properties, antioxidant activity and cytotoxicity of ethanol-soluble acidic components from Ganoderma atrum

Keywords: BHA; butylated hydroxyanisole; BHT; butylated hydroxytoluene; DPPH; 2,2-diphenyl-1-picrylhydrazyl; EC50; half maximal effective concentration; ESAC; ethanol-soluble acidic components; FBS; foetal bovine serum; GAE; gallic acid equivalents; G. atrum; Ganod

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Restoration of viral epithelial tropism improves immunogenicity in rabbits and rhesus macaques for a whole virion vaccine of human cytomegalovirus

Keywords: Human cytomegalovirus; Vaccine; Neutralizing antibody; Pentameric gH complex; Viral epithelial tropism; HCMV; human cytomegalovirus; NT50; reciprocal of serum dilution to neutralize 50% of input virions; GMT; geometric mean titer; EC50; effective concentr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Isolation of powerful antioxidants from the medicinal halophyte Limoniastrum guyonianum

Keywords: DPPH; 2,2-diphenyl-1-picrylhydrazyl; IC50; Inhibition Concentration at 50 percent; EC50; effective concentration at which the absorbance was 0.5; GAE; gallic acid equivalents; BHT; butylated hydroxytoluene; BHA; butylated hydroxyanisole; TFA; trifluoroace

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacophore modeling for hERG channel facilitation

Keywords: hERG; human ether-a-go-go-related gene; 3D-QSAR; three-dimensional-quantitative structure activity relationships; V1/2; the half maximal of voltage dependence of activation; IC50; the half maximal concentration for inhibition; EC50; the half maximal conce

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Comparison in antioxidant action between α-chitosan and β-chitosan at a wide range of molecular weight and chitosan concentration

Keywords: FC; form of chitosan; Mw; molecular weight; CS; concentration of chitosan; C∗; coil-overlap concentration; DDA; degree of deacetylation; DPPH; 1,1-diphenyl-2-picrylhydrazyl; EDTA; ethylenediaminetetraacetic acid; T (%); transmittance; [η]; intrinsic vi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Toxicity assessment of various ionic liquid families towards Vibrio fischeri marine bacteria

Keywords: Ionic liquids; Guanidinium; Imidazolium; Phosphonium; Toxicological tests; Ionic liquid features; Functionalization; Microtox® tests; Vibrio ficheri; EC50

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Endothelial nitric oxide synthase enhancer for protection of endothelial function from asymmetric dimethylarginine-induced injury in human internal thoracic artery

Keywords: 23.1; 33; ADMA; asymmetric dimethylarginine; ANOVA; analysis of variance; CI; confidence interval; DMSO; dimethyl sulfoxide; Emax; maximal relaxation; EC50; 50% effective concentration; eNOS; endothelial nitric oxide synthase; LITA; left internal thoracic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Comparison of the cytotoxic responses of Escherichia coli (E. coli) AMC 198 to different fullerene suspensions (nC60)

Keywords: nC60; Cytotoxicity; EC50; Cytoprotection

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Alteration of serotonin system by polychlorinated biphenyls exposure

Keywords: 5-HIAA; 5-hydroxy-indole acetic acid; 5-HT; 5-hydroxytriptophan (serotonin); AAAD; aromatic l-aminoacid decarboxylase; ACTH; adrenocorticotropic hormone; AhR; aryl hydrocarbon receptor; ARNT; AhR nuclear translocator; BSID; Bayley scales of infant develop

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells

Keywords: Angiogenesis; Human umbilical vein endothelial cells; Migration; Natural products; Receptors; AR; androgen receptor; BES1; BRI1 EMS Suppressor 1; BIN2; Brassinosteroid-Insensitive 2; BRI1; Brassinosteroid-Insensitive 1; BRs; brassinosteroids; DMSO; dimeth

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of corticotropin releasing factor receptor type 2 in the heart by corticotropin releasing factor offers cytoprotection against ischemic injury via PKA and PKC dependent signaling

Keywords: CRF; corticotrophin releasing factor; CRFR; corticotrophin releasing factor receptor; MEK½; mitogen activated protein kinase; PKC; protein kinase C; PKA; protein kinase A; ACTH; adrenocorticotropic hormone; UCN; urocortin; ERK½; extracellular signal-reg

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Skeletal tissues in Mozambique tilapia (Oreochromis mossambicus) express the extracellular calcium-sensing receptor

Keywords: CaSR; calcium-sensing receptor; EC50; effective concentration producing a 50% response; CRD; cysteine-rich domain; ECD; extracellular domain; GPCR; G protein-coupled receptor; ICD; intracellular domain; IHC; immunohistochemistry; RT-PCR; reverse transcrip

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl]purine nucleosides

Keywords: Acyclic nucleoside phosphonate; Prodrugs; Mitsunobu reaction; Antiviral evaluation; VZV; varicella zoster virus; VV; vaccinia virus; HSV; herpes simplex virus; VSV; vesicular stomatitis virus; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; CC50; compo

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Estimation of antiradical properties of antioxidants using DPPH assay: A critical review and results

Keywords: DPPH; Kinetics; Antioxidants; Radical scavenging; EC50;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Comparative efficiency of macroalgal extracts and booster biocides as antifouling agents to control growth of three diatom species

Keywords: Antifouling; Ceramium botryocarpum; Sargassum muticum; Booster biocides; Diatoms; EC50;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleThe cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection

Keywords: HCV; hepatitis C virus; CsA; cyclosporin A; EC50; 50% effective concentration; HIV-1; Human Immunodeficiency Virus Type-1; PPIase; peptidyl prolyl isomerase; TEAE; treatment-emergent adverse event; CTCAE; Common Terminology Criteria for Adverse Events; IF

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleA phase 1, randomized, placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C

Keywords: AUC; area under the plasma concentration-time curve; BMI; body mass index; EC50; 50% effective inhibitory concentration; EC90; 90% effective inhibitory concentration; HCV; hepatitis C virus; PEG-IFN; peginterferon alfa; RBV; ribavirin; NS5A protein; Vir

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

In vitro assessment of antioxidant and antibacterial properties of Terminalia chebula Retz. leaves

Keywords: Terminalia chebula Retz; In vitro; Antioxidant; Antibacterial activity; IC50; EC50;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Human colon cell culture models of different transformation stages to assess conjugated linoleic acid and conjugated linolenic acid metabolism: Challenges and chances

Keywords: AA; arachidonic acid; CD; conjugated dienoic; CFA; conjugated fatty acid; CLA; conjugated linoleic acid; CLnA; conjugated linolenic acid; EC50; 50% effective concentration; ELOVL1/2/5/6; fatty acid elongase 1/2/5/6 (elongation of very long chain fatty aci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Enhanced inhibition of foot-and-mouth disease virus by combinations of porcine interferon-α and antiviral agents

Keywords: CPE; cytopathic effect; CC50; cytotoxic concentration required to reduce cell viability by 50%; EC50; effective concentration required to reduce virus-induced cytopathogenicity by 50%; FMD; foot-and-mouth disease; FMDV; foot-and-mouth disease virus; Guani

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Correlating the structure and composition of ionic liquids with their toxicity on Vibrio fischeri: A systematic study

Keywords: Ionic liquids; Toxicity; Vibrio fischeri; EC50;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Gut and airways relaxant effects of Carum roxburghianum

Keywords: ACh; acetylcholine; ANOVA; analysis of variance; CaCl2; calcium chloride; CCh; carbachol; CI; confidence interval; C.oil; castor oil; CRCs; concentration-response curves; EC50; median effective concentration; EDTA; ethylenediaminetetra acetic acid; Cr.C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Ecotoxicity evaluation and removal of sulfonamides and their acetylated metabolites during conventional wastewater treatment

Keywords: Wastewater; Sulfonamides; Metabolites; Removal efficiencies; EC50; Environmental risk assessment;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Bio-oils from biomass slow pyrolysis: A chemical and toxicological screening

Keywords: CS; corn stalks; CSFing; cancer slope factor by ingestion; CSFinh; cancer slope factor by inhalation; d.b.; dry basis; EC50; effective concentration 50%; GC-MS; gas chromatography-mass spectrometry; LC50,i; lethal concentration 50% by inhalation.; LD5

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

EPs® 7630 (Umckaloabo®), an extract from Pelargonium sidoides roots, exerts anti-influenza virus activity in vitro and in vivo

Keywords: EC50; half maximal effective concentration; IAV; influenza A virus; CC50; half maximal cytotoxic concentration; MDCK; Madin-Darby canine kidney; MLD50; half maximal mouse lethal dose; MOI; multiplicity of infection; TCID50; half maximal tissue culture inf

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Protein Engineered Variants of Hepatocyte Growth Factor/Scatter Factor Promote Proliferation of Primary Human Hepatocytes and in Rodent Liver

Keywords: Growth Factor; Cirrhosis; Mouse Model; Binding Mutant; BrdU; bromodeoxyuridine; EC50; half-maximal effective concentration; FasL; Fas ligand; HGF/SF; hepatocyte growth factor/scatter factor; HSPG; heparan sulfate proteoglycan; PARP; poly(adenosine diphosp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

In silico assessment: Suggested homology of chickpea (Cicer arietinum L.) legumin and prediction of ACE-inhibitory peptides from chickpea proteins using BLAST and BIOPEP analyses

Keywords: AA(s); amino acid(s); ACE; angiotensin I-converting enzyme; BIOPEP; bioactive peptides; BLAST; basic local alignment search tool; EC50; half maximal effective concentration; MW(s); molecular weight(s); NCBI; National Center for Biotechnology Information;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Causes of toxicity to Hyalella azteca in a stormwater management facility receiving highway runoff and snowmelt. Part II: Salts, nutrients, and water quality

Keywords: APHA; American Public Health Association; BC; British Columbia; BMP; best management practice; CALA; Canadian Association for Laboratory Accreditation; CCME; Canadian Council of Ministers of the Environment; CEPA; Canadian Environmental Protection Act; CI

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus

Keywords: AFM; atomic force microscopy; CC50; 50% cytotoxic concentration; CPE; cytopathic effect; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DPBS; Dulbecco's phosphate-buffered saline; EC50; half maximal effective concentration; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Evaluation of cytotoxicity of different tobacco product preparations

Keywords: CAS; complete artificial saliva; CD; cluster of differentiation; COPD; chronic obstructive pulmonary disease; CVD; cardio vascular disease; DMSO; dimethyl sulfoxide; IL; interleukin; IRB; internal review board; NK cells; natural killer cells; PAHs; polycy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model

Keywords: ADAM12; disintegrin and metalloproteinase domain-containing protein 12; α9β1; integrin receptor composed of α9 and β1 sub-units; C2C12; a clonal cell derived from mouse skeletal muscle; EC50; effective concentration 50%; ELISA; enzyme-linked immunosor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Ching-fang-pai-tu-san inhibits the release of influenza virus

Keywords: AFM; atomic force microscopy; CC50; 50% cytotoxic concentration; CFPTS; ching-fang-pai-tu-san; CPE; cytopathic effect; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DPBS; Dulbecco's phosphat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه