دانلود مقالات ISI درباره Gpcr + ترجمه فارسی

WNK4 kinase negatively regulates the surface expression of Muscarinic M3 receptor

Keywords: WNK4; with-no-lysine[K] kinase 4; M3R; muscarinic M3 receptor; GPCR; G-protein coupled receptor; PHAII; pseudohypoaldosteronism type II; HEK; human embryonic kidney; SAPK; STE20/SPS1-related proline/alanine-rich kinase; ORS; oxidative stress responsive ki

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Herpesvirus-encoded GPCRs rewire cellular signaling

Keywords: GPCR; Chemokines; Chemokine receptors; Cancer; Inflammation; KSHV; EBV; HCMV;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The Drosophila genes CG14593 and CG30106 code for G-protein-coupled receptors specifically activated by the neuropeptides CCHamide-1 and CCHamide-2

Keywords: GPCR; Neuropeptide; Genomics; Drosophila; Insects; Arthropods;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Syntrophin isoforms play specific functional roles in the α1D-adrenergic receptor/DAPC signalosome

Keywords: AR; adrenergic receptor; DAPC; dystrophin-associated protein complex; ERK; extracellular signal regulated kinase; GPCR; G-protein coupled receptor; HEK; human embryonic kidney; KO; knock-out; PDZ; PSD95/DlgA/Zo-1; G-protein coupled receptor; α1-adrenergi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of the Drosophila and Tribolium receptors for the recently discovered insect RYamide neuropeptides

Keywords: GPCR; Neuropeptide; Neuropeptide Y; Neuropeptide F; Short neuropeptide F; RYamide; Feeding; Drosophila; Tribolium; Insects;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Capturing of the free cysteine residue in the ligand-binding site by affinity labeling of the ORL1 nociceptin receptor

Keywords: Ac-RYYRIK-NH2; the one-letter amino acid code denotes Ac-Arg-Tyr-Tyr-Arg-Ile-Lys-NH2; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; DMF; N,N-dimethylformamide; EC50; the concentration for the half maximal effective concentration

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function

Keywords: PI3Kδ; phosphoinositide 3-kinase delta; PIP3; phosphoinositide 3,4,5-triphosphates; SH2; Src homology-2; PH; pleckstrin homology; KD; kinase-dead; KO; knockout; BCR; B cell receptor; GPCR; G protein-coupled receptor; TCR; T cell receptor; FcεRI; high af

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

GPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregation

Keywords: 7TM; seven-transmembrane; ECD; ectodomain; EDTA; 2,2′,2′′,2′′′-(ethane-1,2-diyldinitrilo)tetraacetic acid; EGF-TM7; epidermal growth factor module-containing seven-transmembrane receptor; EGTA; glycol-bis(2-aminoethylether)-N,N,N′,N′-tetra

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Greatly enhanced detection of a volatile ligand at femtomolar levels using bioluminescence resonance energy transfer (BRET)

Keywords: GPCR; Olfactory receptors; ODR-10; Diacetyl; Renilla luciferase; BRET;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Isoform-specific uncoupling of the D2 dopamine receptors subtypes

Keywords: D2l dopamine receptor; D2s dopamine receptor; Minigene; Alternatively-spliced G protein-coupled receptor; D2l; dopamine receptor, long form; D2s; dopamine receptor, short form; GPCR; G protein-coupled receptor; HEK; human embryonic kidney; Insert; D2 alte

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway

Keywords: CB1; cannabinoid receptor 1; CB2; cannabinoid receptor 2; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; GPCR; G-protein coupled receptor; HA; hemagglutinin; HEK; human embryonic kidney; PBS; phosphate buffered saline; WT; wild-type; Can

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

A novel protein kinase C target site in protein kinase D is phosphorylated in response to signals for cardiac hypertrophy

Keywords: CHK; checkpoint kinase; CRD; cysteine rich domain; DAG; diacylglycerol; ET-1; endothelin-1; GPCR; G-protein-coupled receptor; GSK-3β; glycogen synthase kinase-3β; HDAC; histone deacetylase; IKK; IκB kinase; ISO; isoproterenol; MARK; microtubule associa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Lack of heterologous receptor desensitization induced by angiotensin II type 1 receptor activation in isolated normal rat thoracic aorta

Keywords: RAS; renin-angiotensin system; ANG II; angiotensin II; AT1; angiotensin II type 1; AT2; angiotensin II type 2; GPCR; G-protein coupled receptors; BK; bradykinin; NO; nitric oxide; cGMP; cyclic guanosin monophosphate; L-NAME; NG-nitro-l-arginine methyl e

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Binding specificity of the ectodomain of the parathyroid hormone receptor

Keywords: Ibs; inclusion bodies; IMAC; immobilized metal ion affinity chromatography; PTH1R; parathyroid hormone receptor; GPCR; G protein-coupled receptor; Parathyroid hormone (PTH); Parathyroid hormone receptor 1 (PTH1R); GPCR; Peptide spotting; Isothermal titrat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Label-free optical biosensor with microfluidics for sensing ligand-directed functional selectivity on trafficking of thrombin receptor

Keywords: DMR; dynamic mass redistribution; GPCR; G protein-coupled receptor; PAR1; protease activated receptor-1; PAR-AP; PAR activating peptide; RWG; Resonant waveguide grating biosensor; Dynamic mass redistribution; G protein-coupled receptor; Ligand-directed fu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Functional interaction between purinergic receptors: effect of ligands for A2A and P2Y12 receptors on P2Y1 receptor function

Keywords: GPCR; G protein-coupled receptor; A2AR; A2A adenosine receptor; P2Y1R; P2Y1 receptor; P2Y12R; P2Y12 receptor; HEK; human embryonic kidney; 2MeSADP; 2-methylthiol-ADP; ZM241385; 4-(2-[7-amino-2-(2-furyl)[1,2,4]-triazolo[2,3-α][1,3,5]triazin-5-yl amino]eth

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Open conformation of adipokinetic hormone receptor from the malaria mosquito facilitates hormone binding

Keywords: GPCR; Anopheles gambiae; Adipokinetic hormones; Homology modeling; Protein docking; Molecular modeling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H3 receptor are involved in receptor-G-protein coupling

Keywords: GPCR; G-protein coupled receptor; H3R; histamine H3 receptor; HEK; human embryonic kidney; CLIC4; chloride intracellular channel 4; DMEM; Dulbecco's modified Eagle's medium; PBS; phosphate buffered saline; PAGE; polyacrylamide gel electrophoresis; RAMH; R

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane

Keywords: GPCR; G-protein coupled receptor; cAR1; cAMP receptor 1; TIRFM; Total Internal Reflection Microscopy; FRAP; Fluorescence Recovery after Photobleaching; PH; Pleckstrin Homology; TMR; Tetramethylrhodamine; MSD; Mean Square Displacement; Single-molecule TIRF

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Cyclic AMP-mediated immune regulation - Overview of mechanisms of action in T cells

Keywords: AC; Adenylyl cyclase; AKAP; A-kinase anchoring protein; AKAP-KL; AKAP-kidney lung; AKB; A-kinase binding domain; AP-1; Activator protein 1; ATF; Activation transcription factor; C; Catalytic (subunit of PKA); CBP; CREB-binding protein; CNG; Cyclic nucleot

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Small molecule antagonists of CCR8 inhibit eosinophil and T cell migration

Keywords: Chemokine; GPCR; Antagonist; CCR8; Eosinophil; T cell;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Central and C-terminal domains of heterotrimeric G protein gamma subunits differentially influence the signaling necessary for primordial germ cell migration

Keywords: Heterotrimeric G protein; Betagamma; GPCR; Primordial germ cells; Migration

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles

Keywords: DPH; 1,6-diphenyl-1,3,5-hexatriene; Compound-24; 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),40-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide; β1AR; β1-adrenergic receptor; β2AR; β2-adrenergic receptor; CCM; cholesterol consensus motif; CHS; cholestery

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

GnRH receptor mutations in isolated gonadotropic deficiency

Keywords: GnRH, gonadotropin-releasing hormone; GnRHR, gonadotropin-releasing hormone receptor; LH, luteinizing hormone; FSH, follicle-stimulating hormone; IHH, idiopathic hypogonadotropic hypogonadism; nIHH, normosmic idiopathic hypogonadotropic hypogonadism; GPCR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

RGS2 is a primary terminator of β2-adrenergic receptor-mediated Gi signaling

Keywords: AC; adenylyl cyclase; Adv; adenovirus; GPCR; G protein-coupled receptor; βAR; β-adrenergic receptor; WT; wild type; ISO; isoproterenol; CGP; CGP20712A; ICI; ICI 118,551; Tpeak; the time from stimulation to peak shortening; T50; the time from the peak to

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control

Keywords: GPR119 agonists; GPCR; Diabetes; GDIS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Functions of duplicated genes encoding CCAP receptors in the red flour beetle, Tribolium castaneum

Keywords: Neuropeptide; Gene duplication; GPCR; Ecdysis; Heartbeat; Molting; Evolution; Tribolium;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Structure based prediction of subtype-selectivity for adenosine receptor antagonists

Keywords: GPCR; G protein-coupled receptor; Adenosine receptor; Subtype selectivity; Homology modeling; Ligand docking; Conformational sampling; Structure based drug discoveryGPCR, G protein-coupled receptor; AR, adenosine receptor; A2AAR, subtype A2A; TM, transmem

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor

Keywords: AC; adenylyl cyclase; BGH; bovine growth hormone; cAMP; Cyclic adenosine monophosphate; CB1; cannabinoid receptor subtype 1; CB2; cannabinoid receptor subtype 2; CNS; central nervous system; DTT; dithiothreitol; GPCR; G protein-coupled receptor; HA; influ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Cloning and pharmacological characterization of the dog cannabinoid CB2 receptor

Keywords: Cannabinoid receptor; Cloning; Radioligand binding; Species selectivity; Pharmacology; GPCR; cAMP assay;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Functional characterization of heterotrimeric G-proteins in rat diaphragm muscle

Keywords: Diaphragm; Skeletal muscle; G-protein; [35S]GTPγS; GPCR; Myoblast culture; L6 cell line

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

CART peptide stimulation of G protein-mediated signaling in differentiated PC12 Cells: Identification of PACAP 6–38 as a CART receptor antagonist

Keywords: CART; CART peptide; CART receptor; CART binding; GPCR; PC12 cells; PACAP 6–38

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Two chicken neuromedin U receptors: Characterization of primary structure, biological activity and tissue distribution

Keywords: Neuromedin U; GPCR; Chicken; NMUR1; NMUR2

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Alternative G protein coupling and biased agonism: New insights into melanocortin-4 receptor signalling

Keywords: ACTH; adrenocorticotropic hormone; cAMP; cyclic 3′,5′-adenosine monophosphate; AGRP; agouti-related protein; CTX; cholera toxin; ER; endoplasmic reticulum; ERK-1/2; extracellular signal-regulated kinases; FSK; forskolin; GPCR; G protein-coupled recept

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Evolution of GPCR: Change and continuity

Keywords: GPCR; Seven-transmembrane receptor; Evolution; Phylogeny; Population genetics;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?

Keywords: Arrestins; GPCR; Signaling; Chemotaxis; MAPK; PI3K; PDE4; Ubiquitin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Expression of Gαz in C2C12 cells restrains myogenic differentiation

Keywords: AC; adenylyl cyclase; PBS-CMF; Ca2+/Mg2+ free phosphate-buffered saline; DM; differentiation medium; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; GPCR; G protein-coupled receptor; GST; glutathione S-transferase; GM; growth medium; MA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

PAC1hop, null and hip receptors mediate differential signaling through cyclic AMP and calcium leading to splice variant-specific gene induction in neural cells

Keywords: PACAP; pituitary adenylate cyclase-activating polypeptide; PAC1; PACAP type 1 receptor; ic3; third intracellular loop; VIP; vasoactive intestinal polypeptide; STC1; stanniocalcin 1; GPCR; G protein-coupled receptor; AC; adenylate cyclase; PKA; protein kin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Muscarinic receptor family interacting proteins: Role in receptor function

Keywords: Iloop-TAP; intracellular loop tandem affinity purification; GPCR; G protein coupled receptor; mAChRs; muscarinic acetylcholine receptor family; Muscarinic receptors; Interacting proteins; Tandem affinity purification; Signal network; G protein coupled rec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

NMR structural study of the intracellular loop 3 of the serotonin 5-HT1A receptor and its interaction with calmodulin

Keywords: 5-HT1A receptor; GPCR; NMR spectroscopy; Membrane protein; Calmodulin; Intracellular loop 3;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Direct-reversible binding of small molecules to G protein βγ subunits

Keywords: GPCR; G protein-coupled receptor; SIGK; peptide with sequence SIGKAFKILGYPDYD; Gβγ; Heterotrimeric G protein βγ subunits; DTT; Dithiothreitol; SPR; Surface Plasmon Resonance; ELISA; Enzyme Linked Immunosorbent Assay; PLC; Phospholipase C; GRK2; G prot

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Novel participation of transglutaminase-2 through c-Jun N-terminal kinase activation in sphingosylphosphorylcholine-induced keratin reorganization of PANC-1 cells

Keywords: SPC; sphingosylphosphorylcholine; Tgase-2; transglutaminase-2; K8; keratin-8; CTM; cystamine; JNK; c-jun N-terminal kinase; Ser; serine; GPCR; G-protein coupled receptors; TPA; 12-O-tetradecanoylphorbol-13-acetate; PANshTg2; Tgase-2 stably knock-down PANC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Structural determinants of the alpha2 adrenoceptor subtype selectivity

Keywords: Homology modeling; Docking; GPCR; α2-Adrenergic receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Chimeric, mutant orexin receptors show key interactions between orexin receptors, peptides and antagonists

Keywords: Orexin; Hypocretin; GPCR; Chimera; Mutant; Antagonist

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Yellow submarine of the Wnt/Frizzled signaling: Submerging from the G protein harbor to the targets

Keywords: Wnt; Frizzled; GPCR; Heterotrimeric G protein; Rab5

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Fungal mating pheromones: Choreographing the dating game

Keywords: GPCR; MAPK kinase; Signal transduction; Homothallic; Heterothallic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

6-Aryl-3-pyrrolidinylpyridines as mGlu5 receptor negative allosteric modulators

Keywords: mGlu5 NAM; Metabotropic glutamate receptors; GPCR; mGluR; CNS drug discovery

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of the immune response and inflammation by histamine and histamine receptors

Keywords: Histamine receptor; innate immunity; adaptive immunity; immune regulation; G protein-coupled receptor; review; cAMP; Cyclic adenosine monophosphate; DC; Dendritic cell; EPAC; Exchange protein directly activated by cyclic adenosine monophosphate 1; Foxp3

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Nuclear β-adrenergic receptors modulate gene expression in adult rat heart

Keywords: AC; adenylyl cyclase; ATP; adenosine triphosphate; βAR; β-adrenergic receptor; CAMKII; Ca2+/calmodulin-dependent protein kinase II; DNA; deoxyribonucleic acid; DTT; dithiothreitol; ET-1; endothelin 1; ERK; extracellular signal-regulated kinase; GPCR; G

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal

Keywords: AC; adenylyl cyclase; β-AR; β-adrenergic receptor; DADLE; [2-d-alanine, 5-d-leucine]enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DAMGO; [2-d-alanine, 4-N-methylphenylalanine, 5-glycinol]enkephalin = Tyr-d-Ala-Gly-N-methyl-Phe-Gly-ol; DOR; δ-opioid recepto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه