Keywords: گیرنده های کانابینوئید; Marijuana; Cannabinoid; Cannabinoid receptor; Placenta; Uterine endometrium; CNR1; cannabinoid receptor 1; CNR2; cannabinoid receptor 2; CBs; cannabinoids; eCBs; endocannabinoids; ACTB; β-actin;
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Keywords: گیرنده های کانابینوئید; AEA; N-arachidonylethanolamine; CBR; cannabinoid receptor; EA; ethanolamine; EA.HCl; ethanolamine, hydrochloride salt; GD; gestation day; IPEA; N-(isopropyl)ethanolamine; PAF; platelet activating factor; Ethanolamine; Embryo; Choline; Implantation; Rat;
Keywords: گیرنده های کانابینوئید; Stressor controllability; Ventromedial prefrontal cortex; Prelimbic; Endocannabinoids; Cannabinoid receptor; 2-AG; Depolarization induced suppression of inhibition;
Keywords: گیرنده های کانابینوئید; 5-HT; 5-hydroxytryptamine; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMKII; Calcium/calmodulin-dependent protein kinase II; CaV; voltage-gated calcium (channel); CGRP; calcitonin gene-related peptide; CB; cannabinoid receptor; CNS; cen
Keywords: گیرنده های کانابینوئید; 2-AG; 2-arachidonoylglycerol; Aβ; β-amyloid; GABA; γ-amino butyric acid; AD; Alzheimer's diseases; ALS; amyotrophic lateral sclerosis; AEA; anandamide; EAE; autoimmune encephalomyelitis; BBB; blood brain barrier; CDB; cannabidiol; CB; cannabinoid rec
Keywords: گیرنده های کانابینوئید; 4HNE; 4-Hydroxy-2-nonenal; AC; Adenylyl cyclase; AD; Alzheimer's disease; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; cAMP; Cyclic adenosine 3â²,5â²-monophosphate; CB; Cannabinoid receptor; CHO; Chinese hamster ovary; DAL; Dehydro-
Keywords: گیرنده های کانابینوئید; BDNF; brain-derived neurotrophic factor; cDNA; complementary deoxyribonucleic acid; CGRP; calcitonin gene-related peptide; CNR; cannabinoid receptor; CREB; cAMP response element-binding protein; DNA; deoxyribonucleic acid; DRG; dorsal root ganglia; GAP; g
Keywords: گیرنده های کانابینوئید; ACC; anterior cingulate cortex; ATP; adenosine triphosphate; CB; cannabinoid receptor; CD; Chron's disease; CGRP; calcitonin-gene related peptide; CNS; central nervous system; CRF; corticotropin releasing factor; ECC; enterochromaffin cell; ENS; enteric n
Keywords: گیرنده های کانابینوئید; Ab; Antibody; AEU; Allergic Effector Unit; AHR; Airway Hyperresponsiveness; ATP; Adenosine 5â²-triphosphate; BMMC; Bone Marrow derived Mast Cells; CB; Cannabinoid Receptor; CBMC; Cord Blood derived Mast Cells; CCR3; C-C Chemokine Receptor type 3; COPD; C
Keywords: گیرنده های کانابینوئید; WIN; WIN 55,212-2; CBR; cannabinoid receptor; ET; essential tremor; ACPA; arachidonyl-cyclo-propyl-amide; WIN55, 212-2; Harmaline; CB agonism; Tremor; Memory;
Keywords: گیرنده های کانابینوئید; Hypothalamus; Cannabinoid receptor; Post-stroke depression; Middle cerebral artery occlusion; Chronic unpredictable mild stress
Keywords: گیرنده های کانابینوئید; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(1-piperidyl)pyrazo-le-3-carboxamide; BSA; bovine serum albumin; DAMGO; [d-Ala2, N-MePhe4, Gly-ol]-enkephalin; DIEA; diisopropylethylamine; DMF; dimethylformamide; EGTA; ethylene glycol-bis(2-amino
Keywords: گیرنده های کانابینوئید; Cannabinoid receptor; Schizophrenia; Peripheral blood mononuclear cells (PBMC); Lymphocyte; MRNA; MATRICS; Biomarker; Cognition;
Keywords: گیرنده های کانابینوئید; Scopolamine; Basolateral amygdala; Endocannabinoid system; Passive avoidance task; Rat(s); CB1; cannabinoid receptor; i.p.; intraperitoneal; BLA; basolateral amygdala; ACPA; arachydonilcyclopropylamide; ACh; acetylcholine; AD; alzheimer disease; LTP; long
Keywords: گیرنده های کانابینوئید; 2-AG; 2-arachidonyl glycerol; AEA; anandamide; CB; cannabinoid receptor; CBD; cannabidiol; COX-2; cyclooxygenase 2; ERK1/2; extracellular signal-regulated kinase ½; FAAH; fatty acid amide hydrolase; IFN; interferon; IL; interleukin; iNOS; inducible nitri
Keywords: گیرنده های کانابینوئید; autophagy; cannabinoid receptor; lysosomal degradation
Keywords: گیرنده های کانابینوئید; Cannabinoid receptor; Huntington's disease; Social behavior; RotaRod test; DARPP-32;
Keywords: گیرنده های کانابینوئید; Endocannabinoids; cannabinoid receptor; adipose tissue; human peripheral blood mononuclear cells
Keywords: گیرنده های کانابینوئید; 4-AP; 4-aminopyridine; APC; antigen presenting cell; ApoE; apolipoprotein E; ATRA; all-trans-retinoic acid; BBB; blood brain barrier; BBI; Bowman-Birk inhibitor; CB1/2; cannabinoid receptor; CBD; cannabidiol; CNS; central nervous system; DC; dendritic c
Keywords: گیرنده های کانابینوئید; 2-AG; 2-arachidonoylglycerol; 5-HT; 5-hydroxytryptamine anandamide N-arachidonoylethanolamide; BMS; burning mouth syndrome; CB; cannabinoid receptor; CBT; cognitive behavioural therapy; CNS; central nervous system; GABA; γ-Aminobutyric acid; HZ; herpes z
Keywords: گیرنده های کانابینوئید; Endocannabinoid; Anandamide; Cannabinoid receptor; Drugs of abuse; Cocaine
Keywords: گیرنده های کانابینوئید; Maternal behavior; Lactation; Cannabinoid receptor; Oxytocin;
Keywords: گیرنده های کانابینوئید; TRPV; transient receptor potential vanilloid; TRPM; transient receptor potential melastatin; CB1; cannabinoid receptor 1; CAP; capsaicin; CPZ; capsazepine; La3+; lanthanum chloride; BCTC; N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl) tetrahydropyrazi
Keywords: گیرنده های کانابینوئید; Cannabinoid receptor; Adamantane; β-Arrestin; Hit optimization;
Keywords: گیرنده های کانابینوئید; α-β-Hydrolase domain 6; ABHD6; Cannabis; 2-Arachidonylglycerol; Cannabinoid receptor;
Keywords: گیرنده های کانابینوئید; Nasal polyp; mucosa; organ culture; endocannabinoid; cannabinoid receptor; mast cell; stem cell factor; c-Kit; tryptase; chymase; ACEA; Arachidonyl-2-chloroethylamide; AEA; N-arachidonoylethanolamide (anandamide); AM251; N-(piperidin-1-yl)-1-(2,4-dichloro
Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants
Keywords: گیرنده های کانابینوئید; CYP450; CYP2C9 variants; Synthetic cannabinoids; Enzyme kinetics; Toxicity; Î9-THC; (â)-Î9-Tetrahydrocannabinol; P450; cytochrome P450; CYP; specific P450; UGTs; uridine diphosphate (UDP)-glucuronosyltransferases; LC-MS/MS; Liquid chromatography-tande
Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons
Keywords: گیرنده های کانابینوئید; DSE; depolarization-induced suppression of excitation; 2-AG; 2-arachidonoyl glycerol; NAM; negative allosteric modulator; PAM; positive allosteric modulator; EPSC; excitatory postsynaptic current; Allosteric; Orthosteric; G protein-coupled receptor; Canna
The potential protective effects of cannabinoid receptor agonist WIN55,212-2 on cognitive dysfunction is associated with the suppression of autophagy and inflammation in an experimental model of vascular dementia
Keywords: گیرنده های کانابینوئید; Autophagy; Cannabinoid receptor; Cognition; Inflammation; Vascular dementia;
Analysis of the pharmacological properties of JWH-122 isomers and THJ-2201, RCS-4 and AB-CHMINACA in HEK293T cells and hippocampal neurons
Keywords: گیرنده های کانابینوئید; Win 55,212-2 (PubChem CID: 6604176); CP-55,940 (PubChem CID: 4412255); Î9-THC (PubChem CID: 16078); rimonabant (PubChem CID: 104850); JWH-122-4 (PubChem CID: 44466638); RCS-4 (PubChem CID: 56841530); THJ-2201 (PubChem CID: 91864533); AB-CHMINACA (PubChem
Anandamide inhibits FcεRI-dependent degranulation and cytokine synthesis in mast cells through CB2 and GPR55 receptor activation. Possible involvement of CB2-GPR55 heteromers
Keywords: گیرنده های کانابینوئید; AEA; anandamide; BMMCs; bone marrow-derived mast cells; FcεRI; high affinity IgE receptor; 2-AG; 2-arachidonoylglycerol; DNP-HSA; dinitrophenol coupled to human serum albumin (antigen); IgE; immunoglobulin E; TNF; Tumor Necrosis Factor; IL; interleukin;
Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling
Keywords: گیرنده های کانابینوئید; Binge drinking; Nucleus accumbens; Cannabinoid receptor; Neutral antagonist; AM4113;
Melatonin attenuates Î9-tetrahydrocannabinol-induced reduction in rat sperm motility and kinematics in-vitro
Keywords: گیرنده های کانابینوئید; HAM; hyper-activated motility; SR141716; rimonabant; AM-630; iodopravadoline; THC; Î9-tetrahydrocannabinol; CB; cannabinoid receptor; CASA; computer-assisted sperm analyser; CSC; annabis sativa; ZP; zona pellucida; BWW; Biggers-Whitten-Whittingham; B
Assessing the real-time activation of the cannabinoid CB1 receptor and the associated structural changes using a FRET biosensor
Keywords: گیرنده های کانابینوئید; CB1; cannabinoid type 1 receptor; FRET; fluorescence resonance energy transfer; GPCRs; G protein-coupled receptors; HD; Huntington's disease; TM; transmembrane; G-proteins; GTP binding-proteins; cAMP; cyclic adenosine monophosphate; ERK1/2; extracellula
Cross-talk of cannabinoid and endocannabinoid metabolism is mediated via human cardiac CYP2J2
Keywords: گیرنده های کانابینوئید; Î8-THC; Î8-tetrahydracannabinol; Î9-THC; Î9-tetrahydracannabinol; AEA; anandamide; AA; arachidonic acid; CBC; cannabichromene; CBD; cannabidiol; CBG; cannabigerol; CBR; cannabinoid receptor; CBN; cannabinol; -COOH; carboxy; CYP; cytochrome P450; CPR;
Monoacylglycerol lipase inhibitor JZL184 prevents HIV-1 gp120-induced synapse loss by altering endocannabinoid signaling
Keywords: گیرنده های کانابینوئید; HIV gp120; Monoacylglycerol lipase; JZL184; Synapse loss; Cannabinoid receptor; Prostaglandin E2; JZL184, 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (PubChem CID: 25021165);
Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets
Keywords: گیرنده های کانابینوئید; THC; Î9-tetrahydrocannabinol; 5-HT2B; serotonin 2B receptor; AC; adenylyl cyclase; AEA; anandamide; Akt; protein kinase B; cAMP; cyclic adenosine monophosphate; CBR; cannabinoid receptor; CB1R; cannabinoid receptor 1; CB2R; cannabinoid receptor 2; CNS; c
Cannabinoid receptors and TRPA1 on neuroprotection in a model of retinal ischemia
Keywords: گیرنده های کانابینوئید; Endocannabinoid; TRP channel; Oxygen glucose deprivation; TRPA1; Retina; Chick; OGD; Oxygen and Glucose Deprivation; CBR; Cannabinoid receptor; TRP; Transient Receptor Potential; LDH; Lactate Dehydrogenase; CNS; Central Nervous System; MO; Mustard Oil; AE
Concurrent activation of β2-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells
Keywords: گیرنده های کانابینوئید; AC; adenylyl cyclase; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; β2AR; β2-adrenergic receptor; CBR; cannabinoid receptor; ICI-118,551; (erythro-DL-1(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-o
Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease
Keywords: گیرنده های کانابینوئید; AD; Alzheimer's disease; AGC; protein kinase A/protein kinase G/protein kinase C; Akt; protein kinase B; ATG13; autophagy-related gene 13; Aβ; amyloid-beta; BDNF; brain-derived neurotrophic factor; CaMKII; Ca2+/calmodulin-dependent kinase II; cAMP; cyc
Tetrahydroindazole derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists
Keywords: گیرنده های کانابینوئید; Cannabinoid receptor; CB1 receptor; Inverse agonist; Peripheral selectivity; Peripherally restricted;
Tetrahydropyrazolo[4,3-c]pyridine derivatives as potent and peripherally selective cannabinoid-1 (CB1) receptor inverse agonists
Keywords: گیرنده های کانابینوئید; Cannabinoid receptor; CB1 receptor; Inverse agonist; Peripheral selectivity; Peripherally restricted;
1,4-Diazepane compounds as potent and selective CB2 agonists: Optimization of metabolic stability
Keywords: گیرنده های کانابینوئید; Cannabinoid receptor; CB2; 1,4-Diazepane; Metabolic stability
The CB1 antagonist, SR141716A, is protective in permanent photothrombotic cerebral ischemia
Keywords: گیرنده های کانابینوئید; Stroke; Cerebral ischemia; CB1 antagonist; Cannabinoid receptor; Photochemical injury; Permanent occlusion;
Docosahexaenoic acid attenuates in endocannabinoid synthesis in RAW 264.7 macrophages activated with benzo(a)pyrene and lipopolysaccharide
Keywords: گیرنده های کانابینوئید; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine anandamide; BaP; benzo(a)pyrene; CB; cannabinoid receptor; DHEA; N-docosahexaneoyl ethanolamide DHA docosahexaenoic acid; ECBs; endocannabinoids; EAE; eicosapentaenoyl ethanolamide; EPA; eicosapentaen
Formation of OX-1R/CB1R heteromeric complexes in embryonic mouse hypothalamic cells: Effect on intracellular calcium, 2-arachidonoyl-glycerol biosynthesis and ERK phosphorylation
Keywords: گیرنده های کانابینوئید; 2-AG; 2-arachidonoylglycerol; ACEA; arachidonyl-2-chloroethylamide; AgRP; agouti-related peptide; CB1R; cannabinoid receptor; CHO; chinese hamster ovary cells; DAG; diacylglycerol; DAGL; diacylglycerol lipase; ERK; extracellular-signal-regulated kinases;
Endocannabinoid 2-AG and intracellular cannabinoid receptors modulate a low-threshold calcium spike-induced slow depolarizing afterpotential in rat thalamic paraventricular nucleus neurons
Keywords: گیرنده های کانابینوئید; ACSF; artificial cerebrospinal fluid; CBR; cannabinoid receptor; DAG; diacylglycerol; DAGL; DAG lipase; FAAH; fatty acid amide hydrolase; LTS; low-threshold spike; MAGL; monoacylglycerol lipase; PAP; phosphatic acid phosphohydrolase; PA; phosphatidic acid
Cannabinoid receptors are involved in the protective effect of a novel curcumin derivative C66 against CCl4-induced liver fibrosis
Keywords: گیرنده های کانابینوئید; (2E,6E)â2,6-bis(2-(Trifluoromethyl)Benzylidene)Cyclohexanone; Liver fibrosis; Cannabinoid receptor; JNK; NF-κB;
Activation of cannabinoid CB1 receptors suppresses the ROS-induced hypersensitivity of rat vagal lung C-fiber afferents
Keywords: گیرنده های کانابینوئید; Airway hypersensitivity; Vagal lung C-fibers; Reactive oxygen species; Cannabinoid receptor; P2X; Transient receptor potential ankyrin 1; CB; cannabinoid; VLCFs; vagal lung C-fibers; ROS; reactive oxygen species; TRPA1; transient receptor potential ankyri
Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands
Keywords: گیرنده های کانابینوئید; CB2; Cannabinoid receptor; Biphenyl-carboxamides; CB2 agonist; CB2 antagonist; CB2 inverse agonist; Methylhonokiol; Endocannabinoid system;