کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1218460 967606 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of pro- and prebiotics on gastric, duodenal and colonic bioaccessibility of the mycotoxin beauvericin
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Influence of pro- and prebiotics on gastric, duodenal and colonic bioaccessibility of the mycotoxin beauvericin
چکیده انگلیسی


• First study of probiotics influence on some bioactives’ stability in gastrointestinal digestion.
• Influence of several soluble and insoluble prebiotics on BEA bioaccessibility.
• Influence of different probiotic strains on BEA bioaccessibility.
• LC–MS-LIT determination of possible bacteria-produced BEA degradation by-products.

Beauvericin (BEA) is a bioactive compound produced by the secondary metabolism of several Fusarium strains and known to have various biological activities. This study investigates the influence of several dietary fibers (galactomanan, glucomannan, citrus fiber, bamboo fiber, carrot fiber, pie fiber, β-glucan, xilan, and cellulose) and probiotic strains (Lactobacillus animalis, Lb. casei, Lb. casei, Lb. plantarum, Lb. rhuminis, Lb. casei casei, Bifidobacterium breve, Bf. Adolescents, Bf. bifidum, Corynebacterium vitaeruminis, Streptococcus faecalis, Eubacterium crispatus, and Saccharomyces cerevisiae) on the minor Fusarium mycotoxin BEA bioaccessibility employing a model solution. The bioaccessibility was determined using a simulated gastrointestinal digestion that mimics the physiological conditions of the digestive tract until the colonic compartment. The determination of BEA in the intestinal fluids was carried out by liquid chromatography–mass spectrometry detection (LC–MS). The reduction of BEA bioaccessibility in the experiments carried out using the prebiotic compounds ranged from 60 to 80%, whereas in the trials carried out using the probiotic strains the bioaccessibility observed ranged from 30 to 85%. A BEA degradation product produced by colonic fermentation was identified using the technique of LC–MS-LIT.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Food Composition and Analysis - Volume 32, Issue 2, December 2013, Pages 141–149
نویسندگان
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