کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5137666 1494535 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of pressed degreased walnut meal extracts on lipid metabolism in postnatally monosodium glutamate-induced mice and 3T3-L1 preadipocytes
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Effects of pressed degreased walnut meal extracts on lipid metabolism in postnatally monosodium glutamate-induced mice and 3T3-L1 preadipocytes
چکیده انگلیسی
Twelve polyphenols were identified in the extracts (WMP) from cold pressed degreased walnut meal by UPLC-ESI-MS, among which glansreginin A, gallic acid, ellagic acid and ellagic acid 4-O-xyloside took up the majority proportion. The potential of WMP to improve glucose and lipid metabolism was investigated by the postnatally monosodium glutamate (MSG)-induced mice. The levels of serum total cholesterol, triacylglycerols, low-density lipoprotein cholesterol, glucose, and adiponectin, ascending in the MSG group, had a significant decrease after the WMP treatment with the corresponding increase of high-density lipoprotein cholesterol level. The administration of WMP suppressed the weight gain and fat accumulation. Furthermore, activities of alanine transaminase, aspartate transaminase and malondialdehyde level decreased obviously compared to the MSG group, however, activities of glutathione peroxidase and superoxide dismutase went higher after the WMP treatment in liver. Our findings have posed WMP the potential to treat obesity and related disorders by improving glucose and lipid metabolism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Functional Foods - Volume 31, April 2017, Pages 89-96
نویسندگان
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