کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5856726 1131981 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development of a risk management tool for prioritizing chemical hazard-food pairs and demonstration for selected mycotoxins
ترجمه فارسی عنوان
توسعه یک ابزار مدیریت ریسک برای اولویت بندی جفت مواد غذایی خطرناک شیمیایی و تظاهرات برای انتخاب متیوکسین ها
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
We developed a simple tool for ranking chemical hazard-food pairs to assist policy makers and risk managers selecting the hazard-food pairs that deserve more attention and need to be monitored during food safety inspections. The tool is based on the derivation of a “Priority Index” (PI) that results from the ratio of the potency of the hazard and the consumer exposure. The potency corresponds to a toxicity reference value of the hazard, whereas the exposure results from the combination of the concentration of the hazard in the food, and the food consumption. Tool's assumptions and limitations are demonstrated and discussed by ranking a dataset of 13 mycotoxins in 26 food items routinely analyzed in Switzerland. The presented ranking of mycotoxin-food pairs has to be considered as relative due to scarce exposure data availability, and uncertainties in toxicity reference values. However, this representative example allows demonstrating the simplicity and the ability of the PI tool to prioritize chemical hazard-food pairs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 72, Issue 2, July 2015, Pages 257-265
نویسندگان
, , , , ,