کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6022614 1580683 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Induction of thioredoxin-interacting protein is mediated by oxidative stress, calcium, and glucose after brain injury in mice
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Induction of thioredoxin-interacting protein is mediated by oxidative stress, calcium, and glucose after brain injury in mice
چکیده انگلیسی
► Ischemic-reperfusion injury increases expression of Txnip protein in mice. ► Txnip can be induced in neurons by oxidative stress without the presence of glucose. ► Txnip and other gene profiles are altered by oxidative stress or glucose. ► Induction of Txnip is mediated by calcium in an OGD and reoxygenation model. ► Down-regulation of Txnip by siRNA is neuroprotective after OGD stimulus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Disease - Volume 46, Issue 2, May 2012, Pages 440-449
نویسندگان
, , , , ,