Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes

Inducible proliferation of TH17(22) with memory cell characteristics is seen in the lungs of patients with CF. The function of these individual subpopulations will require further study regarding their development. T cells are likely not the exclusive producers of IL-17 and IL-22, and this will require further characterization.