دانلود مقالات ISI درباره Prnp + ترجمه فارسی

تجزیه و تحلیل ژن پروتون پریون در آتروفی چند سیستم

Analysis of the prion protein gene in multiple system atrophy

Keywords: Multiple system atrophy; PRNP; Prion disease; Prion protein; Sporadic Creutzfeld-Jakob disease; α-synuclein; α-syn; confidence intervals; CI; cytoplasmic inclusions; GCIs; multiple system atrophy; MSA; sporadic Creutzfeld-Jakob disease; sCJD; odds ratio

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

بیماری های پریون: ملاحظات جدید

Prion diseases: New considerations

Keywords: α-syn; α-synuclein; Aβ; β-amyloid; AD; Alzheimer's disease; ADAMs; a disintegrin and metalloproteinases; ALS; amyotrophic lateral sclerosis; BSE; bovine spongiform encephalopathy; CJD; Creutzfeldt-Jakob disease; CNS; central nervous system; CSF; cer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

پلی مورفیسم ژن پروتئین پینون در ارتباط با حساسیت آنسفالوپاتی گاو به طور قابل توجهی بین گاو و گاومیش

The prion protein gene polymorphisms associated with bovine spongiform encephalopathy susceptibility differ significantly between cattle and buffalo

Keywords: PRNP; Polymorphisms; BSE; Buffalo; Divergence; Genetic differences;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

ایجاد یک سیستم بیان سریع و مقیاس پذیر ژن در دام با یکپارچگی خاص سایت

Establishment of a rapid and scalable gene expression system in livestock by site-specific integration

Keywords: ColA1; α1 (I) procollagen locus; puro; Puromycin N-acetyl-transferase gene; hygro; hygromycin resistance gene; HR; homologous recombination; SCNT; somatic cell nuclear transfer; DT-A; diphtheria toxin A gene; CMV; cytomegalovirus; EGFP; enhanced green fl

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

عدم تأثیر بیان ژن پروتئین پریون در تشنج ناشی از کینات در موش سوری: مطالعاتی که با استفاده از ژنوتیپ های کونژنی، کایزوژنیک و ترانس ژنیک

Lack of influence of prion protein gene expression on kainate-induced seizures in mice: Studies using congenic, coisogenic and transgenic strains

Keywords: KA; kainic acid; i.p.; intraperitoneally; PrP; prion protein; RML; Rocky Mountain Laboratories; prion; kainic acid; seizures; Prnp; flanking genes; knockout mice;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Expression of recombinant human lysozyme in bacterial artificial chromosome transgenic mice promotes the growth of Bifidobacterium and inhibits the growth of Salmonella in the intestine

Keywords: BAC; bacterial artificial chromosome; CPSF6; cleavage and polyadenylation specific factor 6; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; hLF; human lactoferrin; hLZ; human lysozyme; LB; lysogeny broth; PRNP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease

Keywords: ACN; Acetonitrile; AD; Alzheimer's disease; AMF; ammonium formate; ATP; adenosine-triphosphate; BzATP; 3′-O-(4-Benzoyl)benzoyl ATP, strong agonist for P2X7 receptor; CNS; central nervous system; DMEM; Dulbecco's Modified Eagle's Medium; DMF; dimethylfor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Keywords: 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul

دانلود رایگان متن کامل مقاله ISI 131 صفحه سال انتشار : 2018 سفارش ترجمه

Genetic report abstractClinical features of Chinese patients with Gerstmann-Sträussler-Scheinker identified by targeted next-generation sequencing

Keywords: Gerstmann-Sträussler-Scheinker; Prion diseases; PRNP; Targeted next-generation sequencing;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Omics analysis of mouse brain models of human diseases

Keywords: Adam23; ADAM metallopeptidase domain 23; Alcam; activated leukocyte cell adhesion molecule; Apoe; apolipoprotein E; Atp5l; ATP synthase, H + transporting, mitochondrial Fo complex subunit G; Cct8; chaperonin containing TCP1 subunit 8; Cd82; CD82 molecule

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Expression of BSE-associated proteins in the CNS and lymphoreticular tissues of cattle and buffalo

Keywords: BSE; PRNP; SPRN; Cattle; Buffalo;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

PRNP polymorphisms in Tunisian sheep breeds

Keywords: PRNP; Sheep; Polymorphism; Tunisia;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease

Keywords: Alzheimer's disease; Neurodegenerative dementia; APP; PSEN1; PSEN2; MAPT; GRN; PRNP; Exome sequencing;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Analysis of the influence of the PrP genotype on the litter size in Polish sheep using classification trees and logistic regression

Keywords: PRNP; Sheep; Litter size; Classification trees; Logistic regression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A nonsense mutation in PRNP associated with clinical Alzheimer's disease

Keywords: Alzheimer's disease; Prion; PRNP; Nonsense mutation; Exome sequencing;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line

Keywords: AOX1; aldehyde oxidase 1; ARE; antioxidant response element; B2M; β-2-micoglobulin; BDE-47; 2,2′,4,4′-tetra-BDE; BSO; buthionine sulfoximine; CMV; cytomegalovirus; COX-2; cyclooxygenase-2; DHCR24; 24-dehydrocholesterol reductase; DMSO; dimethyl sulfo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Clinical and familial characteristics of eight Chinese patients with T188K genetic Creutzfeldt-Jakob disease

Keywords: Genetic CJD; T188K; PRNP; Creutzfeldt-Jakob disease; Surveillance;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular cloning and sequence analysis of prion protein gene in Xiji donkey in China

Keywords: TSEs; transmissible spongiform encephalopathies; CJD; Creutzfeldt-Jakob disease; vCJD; variant Creutzfeldt-Jakob diseases; BSE; bovine spongiform encephalopathy; CWD; chronic wasting disease; FME; feline spongiform encephalopathy; TME; mink spongiform

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Lysine hydroxylation and O-glycosylation in the globular, C-terminal region of mammalian-expressed, recombinant PrP

Keywords: CAD; collisionally activated dissociation; CHO; Chinese hamster ovary; GPI; glycosylphosphatidylinositol; MS; mass spectrometry; MS/MS; tandem mass spectrometry; PRNP; the gene encoding the prion protein; PrPC; cellular prion protein; PrPSc; scrapie isofo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The association between the methionine/valine (M/V) polymorphism (rs1799990) in the PRNP gene and the risk of Alzheimer disease: An update by meta-analysis

Keywords: Alzheimer disease; PRNP; Meta-analysis; Polymorphism; Risk

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A novel promoterless gene targeting vector to efficiently disrupt PRNP gene in cattle

Keywords: Gene targeting vector; Enrichment efficiency; Promoterless; PRNP; Knockout; Cattle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk

Keywords: Variant CJD; GWAs; Phosphatidylinositol; PRNP; MTMR7; NPAS2; PLCD3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series

Keywords: APP; Duplication; PRNP; Prion; Chromosome 21; Dementia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Toward understanding Machado-Joseph disease

Keywords: ATXN3; ataxin-3; bZIP; basic leucine zipper motif; CBPC; REB binding protein; cDNA; complementary DNA; CHIP; C-terminus of Hsc70 interacting protein; CK2; casein kinase 2; CMV; cytomegalovirus; CNS; central nervous system; CREB; cAMP-response element bind

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular cloning and polymorphism analysis of the prion protein gene in Tan sheep of Ningxia, China

Keywords: TSE; transmissible spongiform encephalopathies; CJD; Creutzfeldt-Jakob disease; BSE; bovine spongiform encephalopathy; PrP; prion protein; PrPc; cellular prion protein; PRNP; prion protein gene; SNPs; single nucleotide polymorphisms; ARQ; A136R154Q171;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Astma i otyłość - czy można mówić o wspólnych uwarunkowaniach genetycznych tych chorób?

Keywords: astma; otyłość; genetyka; GWAS - badania asocjacji genomu; badania genów-kandydatów; bronchial asthma; obesity; GWAS - genome-wide association study; ACE; angiotensin converting enzyme-enzym konwertujący angiotensynę; ADR; adrenergic receptor-r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Rare E196K mutation in the PRNP gene of a patient exhibiting behavioral abnormalities

Keywords: Creutzfeldt-Jakob disease; Transmissible spongiform encephalopathies; Genetic; Prion protein gene; PRNP; Point mutation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Cellular prion protein overexpression disturbs cellular homeostasis in SH-SY5Y neuroblastoma cells but does not alter p53 expression: a proteomic study

Keywords: prion protein; signal transduction; cytoskeleton; protein folding; annexin V; transgelin 2; ADHX; alcohol dehydrogenase class III; ANXA5; annexin V; CV028; UPF0027 protein; DMEM; Dulbecco's modified Eagle medium; FCS; fetal calf serum; FKBP4; FK506-bindin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Genetic susceptibility to chronic wasting disease in free-ranging white-tailed deer: Complement component C1q and Prnp polymorphisms

Keywords: C1q; Candidate gene; Chronic wasting disease; Complement system; Conditional logistic regression; Prion; Prnp; Transmissible spongiform encephalopathy; White-tailed deer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Cellular prion protein modulates age-related behavioral and neurochemical alterations in mice

Keywords: aging; cellular prion protein (PrPC); behavior; acetylcholinesterase (AChE); synaptophysin; caspase-3; AChE; acetylcholinesterase; AD; Alzheimer's disease; ANOVA; analysis of variance; DAB; 3,3′-diaminobenzidine; DG; dentate gyrus; DTNB; dithiobisnitrob

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Coordinate regulation of bovine prion protein gene promoter activity by two Sp1 binding site polymorphisms

Keywords: Prion; BSE; Promoter; Sp1; PRNP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Prion proteins: Physiological functions and role in neurological disorders

Keywords: Adaptive immunity; Aging; Alzheimer disease; Cognition; Down syndrome; Innate immunity; Lymphocytes; Neuroprotection; Primary progressive aphasia; Prion protein; Prnp; PrP; Wilson disease

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Research ReportMild cognitive deficits associated to neocortical microgyria in mice with genetic deletion of cellular prion protein

Keywords: PrPC; cellular prion protein; Prnp; gene that codify PrPC protein; Prnp+/+; PrPC expressing mouse; Prnp0/0; PrPC-null mice; FL; freeze-lesion; MCD; malformation of cortical development; LTP; long-term potentiation; LTM; long-term memory; STM; short-term m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

The ubiquitin-proteasome system in spongiform degenerative disorders

Keywords: AD; Alzheimer's disease; AgRP; Agouti related protein; AIDS; acquired immune deficiency syndrome; APP; amyloid precursor protein; ASPA; aspartoacylase gene; Atrn; attractin; BSE; bovine spongiform encephalopathy; CD; Canavan's spongiform leukodystroph

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2008 سفارش ترجمه

Association between the M129V variant allele of PRNP gene and mild temporal lobe epilepsy in women

Keywords: Temporal lobe epilepsy; PRNP

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Regulatory sequences of the PRNP gene influence susceptibility to sporadic Creutzfeldt–Jakob disease

Keywords: Prion protein gene; PRNP; Prion protein promoter; Creutzfeldt–Jakob disease

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Developmental expression of PrP in the post-implantation embryo

Keywords: Prnp; gene encoding the prion protein; PrP; prion protein; PrPC; normal, cellular prion protein; SHa; Syrian hamster; Tg; transgenic; Mo; mouse; CJD; Creutzfeldt-Jakob disease; Prion; Prnp; Expression regulation; Transgenic mice; β-galactosidase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

M129V variation in the prion protein gene and psychotic disorders: Relationship to neuropsychological and psychopathological measures

Keywords: Prion protein; PRNP; Neuropsychology; Symptomatology; M129V; PANSS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

High frequency occurrence of 1-OPRD variant of PRNP gene in gastric cancer cell lines and Chinese population with gastric cancer

Keywords: Prion; PRNP; Polymorphism; 1-OPRD; Gastric cancer;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

V180I mutation of the prion protein gene associated with atypical PrPSc glycosylation

Keywords: Prion disease; V180I mutation; Prion protein gene; PRNP

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Diagnostic des maladies à prions humaines : quel rôle pour le biologiste ?

Keywords: Maladie de Creutzfeldt-Jakob; Prion; PRNP; Démence; Protéine 14-3-3; PrPSc; Creutzfeldt-Jakob disease; Prion; PRNP; Dementia; 14-3-3 protein; PrPSc;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Functional mapping of the bovine Doppel gene promoter region

Keywords: nt; nucleotide(s); βGal; β-galactosidase; CAT; Cm acetyltransferase; Dpl; Doppel protein; DMEM; Dulbecco's modified eagle medium; ELISA; enzyme-linked immunosorbent assay; ORF; open reading frame; FBS; fetal bovine serum; FLOE; fluorescently labelled ol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

The prion protein gene: Identifying regulatory signals using marsupial sequence

Keywords: PRNP; prion protein gene; PrP; prion protein; PrPC; normal isoform of prion protein; PrPSc; pathogenic isoform of prion protein; SPRN; Shadow of prion protein gene; Sho; Shadow protein; ORF; open reading frame; PCR; polymerase chain reaction; RT-PCR; reve

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه