Keywords: کارسینوم ریه سلول غیرکوچک; COPD, chronic obstructive pulmonary disease; NSCLC, non-small cell lung cancer; SBRT, stereotactic body radiotherapy; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; GTV, gross tumour volume; PTV, planning target volume; CCI, Charl
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Keywords: کارسینوم ریه سلول غیرکوچک; Fibronectin 1; Cisplatin resistance; Apoptosis; Migration; Non-small cell lung cancerFN, Fibronectin; NSCLC, non-small cell lung cancer; IC50, 50% inhibitory concentration; ABC, ATP-binding cassette; FBS, fetal bovine serum; A490, absorbance at 490 nm; ΔΔ
Keywords: کارسینوم ریه سلول غیرکوچک; SGK1, serum and glucocorticoid kinase 1; NSCLC, non-small cell lung cancer; PI3K, phosphoinositide-3-kinase; ATCC, American Type Culture Collection; FBS, fetal bovine serum; GFP, green fluorescence protein; PBS, phosphate-buffered salineNSCLC; SGK1; Beta-
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; EGFR, epidermal growth factor receptor; HRT, hormone replacement therapy; ETS, environmental tobacco smoke; PAH, polycyclic aromatic hydrocarbon; HPV, human papilloma virus; IP, interstitial
Keywords: کارسینوم ریه سلول غیرکوچک; CDA, cytidine deaminase; OS, overall survival; ORR, overall response rate; HR, hazard ratio; OR, odds ratio; CI, confidence intervals; NSCLC, non-small cell lung cancer; NOS, Newcastle–Ottawa scale; HWE, Hardy–Winberg equilibriumCytidine deaminase; Single
Keywords: کارسینوم ریه سلول غیرکوچک; COPD, chronic obstructive pulmonary disease; CPG, cigarettes per day; ILCCO, International Lung Cancer Consortium; MeSH, medical subject headings; NSCLC, non-small cell lung cancer; OR, odds ratio; SCLC, small cell lung cancerSmoking behaviors; Chronic ob
Keywords: کارسینوم ریه سلول غیرکوچک; DLS, dynamic light scattering; FTIR, Fourier transform infrared; HDL, high density lipoprotein; HPLC, High Performance Liquid Chromatography; NSCLC, non-small cell lung cancer; PBS, phosphate buffered saline; PC, l-α-phosphatidylcholine; PEG, poly (ethyle
Keywords: کارسینوم ریه سلول غیرکوچک; LC, lung cancer; AC, adenocarcinoma; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; LCC, large cell carcinoma; SCC, squamous cell carcinoma; EGFR, epidermal growth factor receptor; KRAS, Kirsten Ras; SNP, single nucleotide polymorphism;
Keywords: کارسینوم ریه سلول غیرکوچک; DVT, deep venous thrombosis; ESA, erythropoietin stimulating agents; EVTE, early venous thromboembolic events; LVTE, late venous thromboembolic event; NSCLC, non-small cell lung cancer; OS, overall survival; PS, performance status; PVTE, prior venous thro
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; PS, performance status; CT, computed tomographic; RFS, relapse free survival; FVC, forced vital capacity; FEV1, forced expiratory volume in one second; EFS, event-free survival; CRF, chronic renal failure; AS, aortic val
Keywords: کارسینوم ریه سلول غیرکوچک; DFS, disease-free survival; LN, lymph node; NSCLC, non-small cell lung cancer; OS, overall survival
Keywords: کارسینوم ریه سلول غیرکوچک; Treatment delivery; Referral patterns; Population-based analysis; Advanced NSCLCOS, overall survival; NSCLC, non-small cell lung cancer; BC, British Columbia; CPH, Cox Proportional Hazards; MLR, Multinomial logistic regression; MO, medical oncology; RO, r
Keywords: کارسینوم ریه سلول غیرکوچک; cDNA, complementary DNA; CK, cytokeratin; EGFR-TKI, epidermal growth factor receptor tyrosine kinase inhibitor; IHC, immunohistochemistry; NSCLC, non-small cell lung cancer; OS, overall survival; PCR, polymerase chain reaction; RFS, relapse-free survival;
Keywords: کارسینوم ریه سلول غیرکوچک; Cav1, caveolin-1; FBS, fetal bovine serum; EGFR, epidermal growth factor receptor; Erk1/2, extracellular signal-regulated kinases 1 and 2; MMPs, matrix metalloproteinases; NSCLC, non-small cell lung cancer; siRNA, small interfering RNACaveolin-1; Large ce
Keywords: کارسینوم ریه سلول غیرکوچک; Lung cancer; Metastasis; Micro-environment; Metastatic niche; Chemotaxis; Organ-tropismLC, lung cancer; AC, adenocarcinoma; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; LCC, large cell carcinoma; SCC, squamous cell carcinoma; miRNA, mi
Keywords: کارسینوم ریه سلول غیرکوچک; EBUS, endobronchial ultrasound; NSCLC, non-small cell lung cancer; SEER, Surveillance, Epidemiology, and End Results; TBNA, transbronchial needle aspiration; TCR, Texas Cancer Registry
Keywords: کارسینوم ریه سلول غیرکوچک; EGFR, epidermal growth factor receptor; TKI, tyrosine kinase inhibitor; NSCLC, non-small cell lung cancer; LM, leptomeningeal metastasis; CSF, cerebrospinal fluid; PCR, polymerase chain reaction; TTF, time to treatment failure; CNS, central nervous system
Keywords: کارسینوم ریه سلول غیرکوچک; C/G, Cancer/Germline; CTLA-4, cytotoxic T lymphocyte antigen 4; HERV, human endogenous retrovirus; HLA, human leukocyte antigen; HPV, human papilloma virus; MHC, major histocompatibility complex; NSCLC, non-small cell lung cancer; PD-1, programmed death r
Keywords: کارسینوم ریه سلول غیرکوچک; Oncology; Cancer; Eicosapentaenoic acid; Docosohexaenoic acid; Fish oil; Clinical trialDHA, docosohexaenoic acid; EPA, eicosapentaenoic acid; NSCLC, non-small cell lung cancer; ONS, oral nutritional supplement; PUFA, polyunsaturated fatty acid; CRP, C-rea
Total vertebrectomy (Th2) and dissection of the subclavian artery for a superior sulcus tumor invading the spine: A case report
Keywords: کارسینوم ریه سلول غیرکوچک; CT, computed tomography; SST, superior sulcus tumor; SCA, subclavian artery; TMA, trans-manubrial approach; NSCLC, non-small cell lung cancer; CDDP, cisplatinVertebrectomy; Lung cancer; Transmanubrial approach (TMN)
A novel integrative approach to identify lncRNAs associated with the survival of melanoma patients
Keywords: کارسینوم ریه سلول غیرکوچک; lncRNAs, long non-coding RNAs; HOTAIR, Hox transcript antisense RNA; PRC2, Polycomb repressive complex 2; NSCLC, non-small cell lung cancer; MALAT1, metastasis-associated lung adenocarcinoma transcript 1; SPRY4-IT1, SPRY4 intronic transcript 1; BANCR, BRA
Down-regulation of miR-133a as a poor prognosticator in non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; CDK4, cyclin-dependent kinase 4; MMP-14, matrix metalloproteinase-14; IGF-1R, insulin-like growth factor 1; TGFBR1, transforming growth factor, beta receptor 1; EGFR, epidermal growth factor receptor; lung-SCC, lung squa
Aberrant miR-181b-5p and miR-486-5p expression in serum and tissue of non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; SCC, squamous cell carcinoma; AC, adenocarcinoma; CT, computed tomography; miRNA, microRNA; NGS, next-generation sequencing; T, tumor; N, normalNSCLC; Biomarker; MiRNA; Serum; MiR-181-5p; MiR-486-5p
Knockdown of HNRNPA1 inhibits lung adenocarcinoma cell proliferation through cell cycle arrest at G0/G1 phase
Keywords: کارسینوم ریه سلول غیرکوچک; HNRNPA1, Heterogeneous nuclear ribonucleoprotein A1; IκBα, inhibitory subunit of nuclear factor κ B alpha; RNAi, RNA interference; NSCLC, non-small cell lung cancer; TKIs, tyrosine kinase inhibitors; NF-κB, nuclear factor κ B; shRNA, short hairpin RNA; IH
Clinical and CT characteristics of surgically resected lung adenocarcinomas harboring ALK rearrangements or EGFR mutations
Keywords: کارسینوم ریه سلول غیرکوچک; EGFR, epidermal growth factor receptor; ALK, anaplastic lymphoma kinase; TKIs, tyrosine kinase inhibitors; NSCLC, non-small cell lung cancer; PACS, picture archiving and communication system; CEA, serum carcinoembryonic antigen; TDR, tumor shadow disappea
Development and validation of a UHPLC–MS/MS method for simultaneous quantitation the plasma concentration of Sabarubicin and its alcohol metabolite M3 in Chinese small cell lung cancer patients
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; CFDA, China Food and Drug Administration; UHPLC–MS/MS, ultra high performance liquid chromatography–tandem mass spectrometry; IS, internal standard; HPLC-grade, high performance liquid chrom
Synergistic effect of pacritinib with erlotinib on JAK2-mediated resistance in epidermal gowth factor receptor mutation-positive non-small cell lung Cancer
Keywords: کارسینوم ریه سلول غیرکوچک; JAK, Janus kinase; STAT, signal transducers and activators of transcription; EGFR, epidermal growth factor receptor; FLT3, FMS-like tyrosine kinase 3; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; NSCLC, non-small cell lung cancer; T
MCL-1 is the key target of adjuvant chemotherapy to reverse the cisplatin-resistance in NSCLC
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; MCL-1, Myeloid cell leukemia-1; IC50, half maximal inhibitory concentration; CDDP, cisplatin; MMP, mitochondrial membrane potential; CPR-A549, cisplatin resistant A549; DMEM, Dulbecco's modified Eagle medium; MTT, 3-(4,5
Simultaneous determination of gefitinib and its major metabolites in mouse plasma by HPLC–MS/MS and its application to a pharmacokinetics study
Keywords: کارسینوم ریه سلول غیرکوچک; TKI, tyrosine kinase inhibitor; NSCLC, non-small cell lung cancer; LC–MS/MS, liquid chromatography–tandem mass spectrometry; EGFR, epidermal growth factor receptor; MRM, multiple reaction monitoring; CYP, cytochrome P-450; PK, pharmacokinetic; ESI, electr
Ramucirumab: Boon or bane
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; VEGFR-2, vascular endothelial growth factor receptor-2; OS, overall survival; PFS, progression free survival; DCR, disease control rate; ORR, overall response rate; GEJ, gastro-esophageal junction; mCRC, metastatic color
Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function
Keywords: کارسینوم ریه سلول غیرکوچک; MDR, Multidrug resistance; P-gp, glycoprotein P; ABC, ATP-binding cassette; PTX, paclitaxel; DOX, doxorubicin; NSCLC, non-small cell lung cancer; CI, combination index; Rho 123, rhodamin123Tangeretin (PubChem CID: 69077); Paclitaxel (PubChem CID: 36314);
DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; CDDP, cisplatin; IR, ionizing radiation; CDDP-IR, combination treatment with cisplatin followed by ionizing radiation; DDR, DNA damage response; DSB, double strand break; NER, nucleotide excision repair; HRR, homologous
A Potent Derivative of Indolizino[6,7-b]Indole for Treatment of Human Non–Small Cell Lung Cancer Cells 12
Keywords: کارسینوم ریه سلول غیرکوچک; EGFR, epidermal growth factor receptor; ICLs, interstrand DNA cross-links; MDR, multiple drug resistance; NSCLC, Non-small cell lung cancer; TKIs, tyrosine kinase inhibitors; Topo, topoisomerase
Study of circulating IgG antibodies to BIRC5 and MYC in non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; cAg, control antigen; ELISA, enzyme-linked immunosorbent assay; hAgs, human antigens; NC, negative control; NSCLC, non-small cell lung cancer; OD, optical density; QC, quality control; SBI, specific binding index; TAAs, tumor-associated antigensLung cance
Implementing amplicon-based next generation sequencing in the diagnosis of small cell lung carcinoma metastases
Keywords: کارسینوم ریه سلول غیرکوچک; SCLC, small cell lung cancer; NSCLC, non-small cell lung cancer; NE, neuroendocrine; IHC, immunohistochemistry; NGS, next generation sequencing; FFPE, formalin-fixed and paraffin-embedded; SNP, single nucleotide polymorphism; EMT, epithelial mesenchymal t
Comprehensive proteome analysis of fresh frozen and optimal cutting temperature (OCT) embedded primary non-small cell lung carcinoma by LC–MS/MS
Keywords: کارسینوم ریه سلول غیرکوچک; OCT, optimal cutting temperature; MS, mass spectrometry; IHC, immunohistochemistry; NSCLC, non-small cell lung cancer; FFPE, formalin-fixed paraffin-embedded; PVA, polyvinyl alcohol; PEG, polyethylene glycol; LCM, laser capture microdissection; LC, liquid
Dendritic cell immunotherapy combined with cytokine-induced killer cells promotes skewing toward Th2 cytokine profile in patients with metastatic non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; CIK, cytokine-induced killer; CTLs, cytotoxic T lymphocytes; DC, dendritic cell; NSCLC, non-small cell lung cancer; PBMCs, peripheral blood mononuclear cellsDendritic cells; CIK cells; Non-small cell lung cancer; Immune response; Immunotherapy
PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; PTP1B, protein tyrosine phosphatase 1B; NSCLC, non-small cell lung cancer; OS, overall survival; PTPs, protein tyrosine phosphatases; PTKs, protein tyrosine kinasesProtein tyrosine phosphatase 1B; Proliferation; Metastasis; Src; Non-small cell lung cancer
Prognostic value of estrogen receptors mRNA expression in non-small cell lung cancer: A systematic review and meta-analysis
Keywords: کارسینوم ریه سلول غیرکوچک; HR, hazard ratio; 95% CI, 95% confidence interval; NSCLC, non-small cell lung cancer; ESR, estrogen receptor; OS, overall survival; PCR, polymerase chain reaction; IHC, immunohistochemistryLung cancer; Survival; Estrogen receptor; Meta-analysis
TXA9, a cardiac glycoside from Streptocaulon juventas, exerts a potent anti-tumor activity against human non-small cell lung cancer cells in vitro and in vivo
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer; CGs, cardiac glycosides; SJ, Streptocaulon juventas; MTT, 3-(4,5-dimethylibiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; AO, acridine orange; PI, propidium iodide; i.v., intravenous; LTXA9,
Plasma circulating microRNA-944 and microRNA-3662 as potential histologic type-specific early lung cancer biomarkers
Keywords: کارسینوم ریه سلول غیرکوچک; AC, adenocarcinoma; AUC, area under the curve; cDNA, complementary DNA; CT, computed tomography; LD-CT, low-dose spiral computed tomography; miRNA, microRNA; NSCLC, non-small cell lung cancer; ROC, receiver operating curve; SCC, squamous-cell carcinoma; S
Pculin02H, a curcumin derivative, inhibits proliferation and clinical drug resistance of HER2-overexpressing cancer cells
Keywords: کارسینوم ریه سلول غیرکوچک; CHX, cycloheximide; EGFR, epithelial growth factor receptor; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NSCLC, non-small cell lung cancer; PBS, phosphate-buffered saline; PI, propidium iodideHER2; Pculin02H; G2/M arrest; Apoptosis
Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells
Keywords: کارسینوم ریه سلول غیرکوچک; PLK1, Polo-like kinase 1; NSCLC, non-small cell lung cancer; SAC, spindle assembly checkpoint; MCC, mitotic checkpoint complexPLK1; BI2536; Non-small cell lung cancer; Mitosis; Spindle assembly checkpoint; Mitotic catastrophe
Proteomic profiling of hyperplasia/atypia and adenoma-induced by NNK in mouse lung identified multiple proteins as potential biomarkers for early detection
Keywords: کارسینوم ریه سلول غیرکوچک; NNK4, -(methylnitrosamino)-1-(3-pyridyl)-1-butanone; p-XSC, 1,4-phenylenebis(methylene)selenocyanate; iTRAQ, isobaric tags for relative and absolute quantitation; SCLC, small cell lung cancer; NSCLC, non-small cell lung cancer; MS, mass spectrometry; IARC
Structure-activity study of quinazoline derivatives leading to the discovery of potent EGFR-T790M inhibitors
Keywords: کارسینوم ریه سلول غیرکوچک; Quinazoline derivatives; H1975; EGFR-T790M; HCC827; A-431EGFR, Epidermal growth factor receptor; NSCLC, Non-small cell lung cancer; SAR, Structure-activity relationship; DMF, Dimethylformamide; TLC, Thin layer chromatography; THF, Tetrahydrofuran; NMP, N-
Decreased circulating miR-375: A potential biomarker for patients with non-small-cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; miRNA, microRNA; NSCLC, Non-small cell lung cancer; qRT-PCR, Quantitative real-time PCR; OS, Overall survival; HR, Hazard ratios; CI, Confidence intervals; RUN6B, U6 small nuclear RNAmiR-375; Lung cancer; miR-20a; miR-31; Metastasis; Survival
Appropriate Sublobar Resection Choice for Ground Glass Opacity-Dominant Clinical Stage IA Lung Adenocarcinoma : Wedge Resection or Segmentectomy
Keywords: کارسینوم ریه سلول غیرکوچک; FDG, 18F-fluorodeoxyglucose; FOV, field of view; GGO, ground glass opacity; HRCT, high-resolution CT; HU, Hounsfield units; IRB, institutional review board; NSCLC, non-small cell lung cancer; OS, overall survival; RFS, recurrence-free survival; SUVmax, ma
Prognosis value of HIF-1α expression in patients with non-small cell lung cancer
Keywords: کارسینوم ریه سلول غیرکوچک; HIF-1, Hypoxia-inducible factor 1; HIF-1α, Hypoxia-inducible factor 1α; LC, Lung cancer; NSCLC, Non-small cell lung cancer; SCLC, Small cell lung cancer; HR, Hazard ratio; OS, Overall survival; CI, Confidence interval; IHC, ImmunohistochemistryHIF-1α; Pro
Invasive adenocarcinoma of the lung is associated with the upper lung regions
Keywords: کارسینوم ریه سلول غیرکوچک; Non-small cell lung cancer; Tumor location; EmphysemaACwLF, adenocarcinoma with lepidic features; BAC, bronchioloalveolar carcinoma; BMI, body mass index; COPD, chronic obstructive pulmonary disease; NSCLC, non-small cell lung cancer; SEER, surveillance,
Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells
Keywords: کارسینوم ریه سلول غیرکوچک; NSCLC, non-small cell lung cancer; EMSA, electrophoretic mobility shift assay; ChIP, chromatin immunoprecipitation; IHC, immunohistochemistry; RLU, relative luciferase units; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PVDF, polyv