دانلود مقالات ISI درباره Sod1 + ترجمه فارسی

CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit

Keywords: Gene-specific DNA methylation; Toluene exposure; CYP2E1; GSTP1; SOD1; Smoking habit;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The distinct genetic pattern of ALS in Turkey and novel mutations

Keywords: ALS; Turkey; SOD1; C9orf72; TDP-43; FUS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Exploring new pathways of neurodegeneration in ALS: The role of mitochondria quality control

Keywords: ALS; Mitochondria; Mitophagy; SOD1; Parkin; p62

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular chaperones and neuronal proteostasis

Keywords: 17-AAG; 17-allylamino-17-demethoxygeldanamycin; 17-DMAG; 17-dimethylamino-ethylamino-17-demethoxygeldanamycin; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ARSACS; autosomal recessive spastic ataxia of Charlevoix-Saguena

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

“Preconditioning” with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1G93A mice

Keywords: Amyotrophic lateral sclerosis; AMPK; Bioenergetics; Pre-conditioning; Spinal cord; Motoneuron degeneration; SOD1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The anti-inflammatory peptide stearyl-norleucine-VIP delays disease onset and extends survival in a rat model of inherited amyotrophic lateral sclerosis

Keywords: ALS; amyotrophic lateral sclerosis; SOD1; superoxide dismutase 1; VIP; vasoactive intestinal peptide; PACAP; pituitary adenylate cyclase-activating polypeptide; SNV; stearyl-norleucine-VIP; PBS; phosphate-buffered saline; GFAP; glial fibrillary acidic pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Nitroxide delivery system for Nrf2 activation and skin protection

Keywords: ME; microemulsion; SOD1; superoxide dismutase; TPO; tempo (2,2,6,6-tetramethyl-piperidine-1-oxyl); TPL, 4-OH-TPO; tempol (4-hydroxy-TEMPO, 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl); Nrf2; nuclear factor (erythroid derived 2)-like 2, NF-E2 related fac

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Adverse effects of a SOD1-peptide immunotherapy on SOD1G93A mouse slow model of amyotrophic lateral sclerosis

Keywords: ALS; amyotrophic lateral sclerosis; CS; clinical score; ELISA; enzyme-linked immunosorbent assay; FALS; familial amyotrophic lateral sclerosis; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium binding adaptor molecule; IgG; immunoglobulin G;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Punicalagin improves chorioallantoic and yolk sac vasculogenesis and teratogenesis of embryos induced by nicotine exposure

Keywords: Punicalagin; Nicotine; Teratogenesis; Placenta; Yolk sac; Vascularization; ROS; reactive oxygen species; TBARS; thiobarbituric acid reactive substances; MDA; malondialdehyde; SOD1; cytoplasmic superoxide dismutase; GPx1; cytoplasmic glutathione peroxidase

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model

Keywords: ALS; amyotrophic lateral sclerosis; fALS; familial ALS; HD; Huntington disease; HspB8; heat shock protein B8; LBHI; Lewy body-like inclusions; mTOR; mammalian target of rapamycin; PBS; phosphate-buffered saline; PD; Parkinson disease; SD; standard deviati

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Motor neurons with differential vulnerability to degeneration show distinct protein signatures in health and ALS

Keywords: ALS; amyotrophic lateral sclerosis; ANOVA; analysis of variance; ChAT; choline acetyltransferase; CNIII; oculomotor nucleus; CNXII; hypoglossal nucleus; Gabra1; GABAA receptor α1; Gabra2; GABAA receptor α2; Gucy1a3; guanylate cyclase soluble subunit alp

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular pathways associated with the intersex condition in rainbow darter (Etheostoma caeruleum) following exposures to municipal wastewater in the Grand River basin, ON, Canada. Part B

Keywords: APOE; apolipoprotein E; CAV1; caveolin 1; SAA1; serum amyloid A1; EPX; eosinophil peroxidase; PGD; phosphogluconate dehydrogenase; TNNI3; troponin I type 3 (cardiac); HSPB1; heat shock 27 kDa protein 1; SERPINE1; serpin peptidase inhibitor, clade E; INS;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Keap1-Nrf2 regulated redox signaling in utero: Priming of disease susceptibility in offspring

Keywords: CE; Cornified envelope; GCL; Glutamyl cysteine ligase; GDM; Gestational diabetes mellitus; IUGR; Intrauterine growth retardation; NADPH; Nicotinamide adenine dinucleotide phosphate; NQO1; NADPH:quinone oxidoreductase 1; Nrf2; Nuclear factor E2-related fac

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

The superoxide dismutase 1 3′UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1

Keywords: SOD1; 3′UTR; Cancer; AU-rich element; AUF-1; Free radicals;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of Rac1 by thiol oxidation

Keywords: ABD-f; 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole; βME; β-mercaptoethanol; CD; circular dichroism; DMEM; Dulbecco's modified Eagle׳s medium; DTPA; diethylenetriaminepentaacetic acid; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; eN

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Improving the knowledge of amyotrophic lateral sclerosis genetics: novel SOD1 and FUS variants

Keywords: ALS; FTD; SOD1; FUS; C9ORF72; TARDBP; Genetic screening;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

A novel SOD1 mutation p.V31A identified with a slowly progressive form of amyotrophic lateral sclerosis

Keywords: ALS; SOD1; Mutation;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Identify mutation in amyotrophic lateral sclerosis cases using HaloPlex target enrichment system

Keywords: Amyotrophic lateral sclerosis; HaloPlex target enrichment system; SOD1; DCTN1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

SOD1G93A transgenic mouse CD4+ T cells mediate neuroprotection after facial nerve axotomy when removed from a suppressive peripheral microenvironment

Keywords: Motoneuron; T cell; APC; Axotomy; SOD1; ALS; Immune

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Reactive oxygen species mediate IL-8 expression in Down syndrome candidate region-1-overexpressed cells

Keywords: Down syndrome critical region-1; Reactive oxygen species; IL-8; NF-κB; SOD1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Lifespan extension by cranberry supplementation partially requires SOD2 and is life stage independent

Keywords: 4-HNE; 4-hydroxynonenal; cran; cranberry; IR; inverted repeat; MAPK; MAP kinase; RNAi; RNA interference; S6K; S6 kinase; SOD1; superoxide dismutase 1; SOD2; superoxide dismutase 2; SY; sugar-yeast diet; TOR; target of rapamycin; Aging; Dietary interventio

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewWhite matter lactate - Does it matter?

Keywords: ALS; Amyotrophic Lateral Sclerosis; ANLS; astrocyte-to-neuron lactate shuttle; cAMP; cyclic AMP; CAP; compound action potential; MCTs; monocarboxylate transporters; PEPCK; phosphoenolpyruvate carboxykinase; SOD1; superoxide dismutase; energy; lactate; dev

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes

Keywords: ALS; Amyotrophic Lateral Sclerosis; APAF1; Apoptotic protease activating factor 1; BH3-only protein; Bcl-2 homology domain 3-only protein; bid; BH3 interacting domain death agonist; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium-binding ada

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative structural and conformational studies on H43R and W32F mutants of copper-zinc superoxide dismutase by molecular dynamics simulation

Keywords: SOD1; fALS; W32F; H43R; Molecular dynamics; GROMACS;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization

Keywords: SOD1; Misfolding; Heterodimerization; Mutant homodimers; Protein aggregation; Dismutase activity; SEDI; USOD;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic link between Cabeza, a Drosophila homologue of Fused in Sarcoma (FUS), and the EGFR signaling pathway

Keywords: Caz; Cabeza; ALS; Amyotrophic Lateral Sclerosis; FUS; Fused in Sarcoma; EGFR; Epidermal growth factor-receptor; SOD1; Cu/Zn superoxide dismutase; TDP-43; TAR DNA-binding protein of 43 kDa gene; CNS; central nervous system; APF; after pupal formation; ERK

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

SQSTM1 mutations - Bridging Paget disease of bone and ALS/FTLD

Keywords: ALS; amyotrophic lateral sclerosis; aPKC; atypical protein kinase C; C9orf72; chromosome 9 open reading frame 72; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; FUS/TLS; fused in sarcoma/translocated in liposarcoma; GWAS; genome-wi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Altered miRNA expression is associated with neuronal fate in G93A-SOD1 ependymal stem progenitor cells

Keywords: ALS; amyotrophic lateral sclerosis; Ccnd2; cyclin D2; Dlx2; distal-less homeobox 2; epSPCs; ependymal stem/progenitor cells; FALS; familial ALS; GAD 67; glutamic acid decarboxylase 67; GFAP; glial fibrillary acidic protein; Hes1; hairy and enhancer of spl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1

Keywords: PD; Parkinson's disease; PPARγ; peroxisome proliferator-activated receptor gamma; TZDs; thiazolidinediones; RGS; Rosiglitazone; ΔΨm; Mitochondrial membrane potential; ROS; reactive oxygen species; PI; propidium Iodide; TMRM; Tetramethylrhodamine methyl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation

Keywords: ALS; Amyotrophic lateral sclerosis; APP; Amyloid precursor protein; BDNF; brain derived neurotrophic factor; CNS; Central nervous system; ER; endoplasmic reticulum; FTLD-MND; Fronto-temporal lobar degeneration with co-occurrence of motor neuron disease; F

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative proteomic profiling reveals aberrant cell proliferation in the brain of embryonic Ts1Cje, a mouse model of Down syndrome

Keywords: 2-DE; two-dimensional gel electrophoresis; BrdU; bromodeoxyuridine; CACYBP; calcyclin-binding protein; DAB; 3,3′-diaminobenzidine; DAVID; Database for Annotation, Visualization, and Integrated Discovery; DS; Down syndrome; E14.5; embryonic day 14.5; GE;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: An overview of Down syndrome, autism, Fragile X and Rett syndrome

Keywords: Intellectual disability; Mitochondria; Mitochondrial dysfunction; Oxidative phosphorylation; Neurogenesis; Neuroplasticity; Down syndrome; Rett syndrome; Autism; Fragile X; Oxidative stress; Drug development; Epigallocatechine-3-gallate; ANT; adenine nucl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic deletion of MT1/MT2 melatonin receptors enhances murine cognitive and motor performance

Keywords: aCSF; artificial cerebrospinal fluid; ADHD; attention deficit/hyperactivity disorder; ANOVA; analysis of variance; C3B6; mice with a combination C3H/He and C57BL/6 background; cDNA; complementary deoxyribonucleic acid; CAT; catalase; CREB; cAMP response e

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Zebrafish as a model system for mitochondrial biology and diseases

Keywords: 2,5-DHBA; 2,5-dihydroxybenzoic acid; ALS; amyotrophic lateral sclerosis; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; CMT2; Charcot-Marie-Tooth 2; CNS; central nervous system; coA; coenzyme A; COX; cytochrome c oxidase; DA; dopaminergic; dpf; da

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

MDG-1, a polysaccharide from Ophiopogon japonicus, prevents high fat diet-induced obesity and increases energy expenditure in mice

Keywords: Ophiopogon japonicus; Polysaccharide; Anti-obesity; Energy expenditure; Diet induced obesity; Mitochondrial function; T2DM; type 2 diabetes mellitus; HFD; high fat diet; qPCR; quantitative real-time polymerase chain reaction; RER; respiratory exchange rat

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2014 سفارش ترجمه

Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ALS; amyotrophic lateral sclerosis; ALS/PDC; amyotrophic lateral sclerosis-Parkinsonism Dementia Complex of Guam; BMAA; beta-N-methylamino-l-alanine; Ca-AMPA receptors; Ca2 + permeable AMPA r

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2014 سفارش ترجمه

HDL and cognition in neurodegenerative disorders

Keywords: ABC; ATP-binding cassette transporter; AD; Alzheimer's disease; Akt; protein kinase B; ALS; amyotrophic lateral sclerosis; apo; apolipoprotein; Aβ; amyloid-β protein; BBB; blood-brain barrier; CAA; cerebral amyloid angiopathy; CE; cholesterol ester; C

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis

Keywords: SOD1; ALS; Protein aggregation; Neurodegenerative disease; Amyloid;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of mutation in NPC2 by exome sequencing results in diagnosis of Niemann-Pick disease type C

Keywords: NPC; Niemann-Pick type C; NPC1; NPC1 gene; NPC2; NPC2 gene; SMPD1; sphingomyelin phosphodiesterase 1 gene; LDL; low density lipoprotein; HGMD; The Human Gene Mutation Database; ALS; amyotrophic lateral sclerosis; DTR; deep tendon reflex; MRI; magnetic r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Characterization and Hsp104-induced artificial clearance of familial ALS-related SOD1 aggregates

Keywords: ALS; amyotrophic lateral sclerosis; BiFC-FRET; Bimolecular fluorescence complementation-Förster resonance energy transfer; FLIP; fluorescence loss in photobleaching; ROI; region of interest; SOD1; superoxide dismutase 1; Mutant SOD1; Amyotrophic late

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondria and ALS: Implications from novel genes and pathways

Keywords: ALS; Amyotrophic Lateral Sclerosis; CFP; Cyan Fluorescent Protein; ER; Endoplasmic Reticulum; FUS/TLS; Fused in Sarcoma/Translocated in Liposarcoma; GSH; Glutathione; HAT; Histone Acetyl Transferase; HDAC; Histone Deacetylase; ROS; Reactive Oxygen Species

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice

Keywords: ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; C9orf72; chromosome 9 open reading frame 72; DPP6; dipeptidyl-peptidase 6; ELP3; elongator protein 3; ER; endoplasmic reticulum; FUS/TLS; fused in sarcoma/tra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Tuning NF-κB activity: A touch of COMMD proteins

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; COMMD; copper metabolism gene MURR1 domain-containing protein; CRL; Cullin RING ligase; CRM1; chromosome region maintenance 1/exportin 1; CYLD; cylindromatosis; DUB; deubiquitinating enzyme; ENaC;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Overexpression of native PSE1 and SOD1 in Saccharomyces cerevisiae improved heterologous cellulase secretion

Keywords: Saccharomyces cerevisiae; Overexpression; SOD1; PSE1; Cellulase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic analysis and SOD1 mutation screening in Iranian amyotrophic lateral sclerosis patients

Keywords: Amyotrophic lateral sclerosis; ALS; SOD1; p.Asp90Ala; p.D90A; Scandinavian haplotype; Iran;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Posttranscriptional regulation of SOD1 gene expression under oxidative stress: Potential role of ELAV proteins in sporadic ALS

Keywords: Sporadic amyotrophic lateral sclerosis; SOD1; mRNA; Posttranscriptional regulation; ELAV proteins; Peripheral blood mononuclear cells; Motor cortex; Spinal cord;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Increase of oxidative stress by a novel PINK1 mutation, P209A

Keywords: AD; Alzheimer disease; ERK; extracellular signal-regulated kinase; MTT; 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolum bromide; HO-1; heme oxygenase-1; LDH; lactate dehydrogenase; LY294002; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one; MEM; mini

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Galactooligosaccharide improves the animal survival and alleviates motor neuron death in SOD1G93A mouse model of amyotrophic lateral sclerosis

Keywords: ALS; amyotrophic lateral sclerosis; ELISA; Enzyme-linked immunosorbent assay; fALS; familial ALS; GOS; galactooligosacchrides; Hcy; homocysteine; HRP; horseradish peroxidase; iNOS; inducible nitric oxide synthase; MGT; Modified Gomori Trichrome; NADH; nic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies

Keywords: SOD1; CcOX; Bcl-2; Peroxynitrite; Lymphoma; Leukemia; Porphyrins; Free radicals;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه