Keywords: دوکسوروبیسین; DOX, doxorubicin; HSA, human serum albumin; BSA, bovine serum albumin; b-LG, beta-lactoglobulin; FTIR, Fourier transform infraredDoxorubicin; Protein; Drug delivery; Hydrophobicity; Modeling; Spectroscopy
مقالات ISI دوکسوروبیسین (ترجمه نشده)
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Keywords: دوکسوروبیسین; AKR, aldo-keto reductase; SDR, short-chain dehydrogenase/reductase; DAUN, daunorubicin; DOX, doxorubicin; DAUNOL, daunorubicinol; DOXOL, doxorubicinolAnthracycline resistance; Daunorubicin; Aldo-keto reductases; Short-chain dehydrogenases/reductases; Enzy
Keywords: دوکسوروبیسین; IBSD, ion beam sputtering deposition; NPs, nanoparticles; GO, graphite oxide; DOX, doxorubicin; TC, tetracycline; AFM, atomic force microscopy; SEM, scanning electron microscopy; XPS, X-ray photoelectron spectroscopy; CV, cyclic voltammetry; CVs, cyclic v
Keywords: دوکسوروبیسین; PEG, polyethylene glycol(methoxy-PEG2000-DSPE); Tf, transferrin; TfR, transferrin receptor; FR, folate receptor; Dox, doxorubicin; CPP, cell penetrating peptides; MPS, mononuclear phagocytic system; EPR, enhanced permeability and retention; ePC, egg phosp
Keywords: دوکسوروبیسین; Carbon nanotubes; Clinical imaging; MRI; PET; SPECT; X-ray CTacac, acetylacetone; CNTs, carbon nanotubes; CT, computed tomography; CA, contrast agent; DTPA, diethylenetriaminepentaacetic dianhydride; DOX, doxorubicin; EXAFS, extended X-ray absorption fine
Keywords: دوکسوروبیسین; APTMS, 3-aminopropyltrimethoxysilane; Bis-GMA, bisphenol A glycidyl methacrylate; BTME, 1,3-bis(trimethoxysilyl) ethane; CS, chitosan; CTAB, cethyltrimethyl ammonium bromide; CUR, curcumin; DCC, dicyclohexylcarbodiimide; DOX, doxorubicin; DTX, docetaxel;
Keywords: دوکسوروبیسین; Dox, doxorubicin; CG, cashew gum; AO, Anacardium occidentale; CMCG, carboxymethylated cashew gum; Con, concanavalin; ALG, alginate; CHI, chitosan; LsEO, Lippia sidoids essential oil; DDVP, dichlorvos [2,2-dichlorovinyldimethyl phosphate]; MOS, Moringa ole
Keywords: دوکسوروبیسین; DOX, doxorubicin; MM, multiple myeloma; UPS, ubiquitin-proteasome system; ANT, anthracyclin; ROS, reactive oxygen species; SP, standard proteasome; IP, immunoproteasome; PI, proteasome inhibitor; CM, cardiomyocyte; ABP, activity-based probeProteasome; Sub
Keywords: دوکسوروبیسین; cTnT, cardiac troponin T; DOX, doxorubicin; DXZ, dexrazoxane; FDR, false discovery rate; GO, Gene Ontology; ROS, reactive oxygen species; SAL, saline; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labelingDoxorubicin; Dexrazoxane; Mitochondri
Keywords: دوکسوروبیسین; ANAs, antinuclear antibodies; APRPG, Ala-Pro-Arg-Pro-Gly; CAP, capecitabine; CMC, critical micelles concentration; DOPE, dioleoyl(phosphatidylethanolamine); DOTMA, N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride; DOX, doxorubicin; DSPE, dist
Keywords: دوکسوروبیسین; ANOVA, analysis of variance; CAT, catalase; DOX, doxorubicin; DMEM, Dulbecco's modified Eagle's medium; ELISA, high-sensitivity enzyme-linked immunosorbent assay; EDTA, ethylenediaminetetraacetic acid; GSH-Px, glutathione peroxidase; H2O2, hydrogen peroxi
Keywords: دوکسوروبیسین; b-AuNP, biosynthesized gold nanoparticles using Butea monosperma (BM); b-AgNP, biosynthesized silver nanoparticles using Butea monosperma (BM); BM, Butea monosperma; DOX, Doxorubicin; b-Au-500, biosynthesized gold nanoparticles using 500 μL of Butea monos
Keywords: دوکسوروبیسین; ACN, acetonitrile; apoA-1, apolipoprotein A-1; apoE, apolipoprotein E; BSA, bovine serum albumin; CF, carboxyfluorescein; CF-L, CF encapsulated conventional liposome; CF-SL, CF encapsulated sterically stabilized liposome; DOX, doxorubicin; EPR, enhanced p
Keywords: دوکسوروبیسین; AML, Acute myeloid leukaemia; DDS, Drug delivery system; DNR, Daunorubicin; DOX, Doxorubicin; Eme, Emetine; FA, Folate; FR2, Folic acid receptor 2 (β); HEPC, Hydrogenated egg phosphatidylcholine; MTX, Methotrexate; PE, Phosphatidylethanolamine; PEG, Polye
Keywords: دوکسوروبیسین; CE, capillary electrophoresis; DOX, doxorubicin; FITC, fluorescein isothiocyanate; FWHM, full width at half maximum; LIF, laser-induced fluorescence; LOD, limit of detection; PBS, physiological buffer saline; PDMS, poly(dimethylsiloxane); P-gp, P-glycopro
Keywords: دوکسوروبیسین; cTnT, cardiac troponin T; DAB, diaminobenzidine; DOX, doxorubicin; DSBs, double strand breaks; FDR, false discovery rate; IgG, immunoglobin G; IHC, immunohistochemistry; qRT-PCR, quantitative real time polymerase chain reaction; miRNA, microRNA; RT, room
Keywords: دوکسوروبیسین; DOX, doxorubicin; AUC, total area under the plasma concentration–time curve from time zero to time infinity; Cmax, peak plasma concentration; Tmax, time to reach a Cmax; Frel, extent of relative oral bioavailabilityColloidal nanosystem; Medium chain glyce
Keywords: دوکسوروبیسین; Atorvastatin; Doxorubicin; Oxidative stressALT, Alanine transaminase; AST, Aspartate transaminase; Ator, Atorvastatin; Bax, Bcl-2-associated X protein; BUN, Blood urea nitrogen; DOX, Doxorubicin; eNOS, Endothelial nitric oxide synthase; GSH, Reduced gluta
Keywords: دوکسوروبیسین; DTX, docetaxel; DOX, doxorubicin; PTX, paclitaxel; CA-4, combretastatin; PEG, polyethylene glycol; PLA, polylactic acid; DOPC, 1,2-dioleoyl-sn-glycero-3-phosphocholine; DPPC, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; FA, folic acid; FR, folate receptor
Keywords: دوکسوروبیسین; Imperata cylindrica; Colorectal cancer; Prostanoids; Cytotoxicity; Oxidative stressCRC, colorectal cancer; DOX, doxorubicin; IMP, Imperata cylindrica; Indo, indomethacin; MTT, 3- (4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; LTs, leukotrien
Keywords: دوکسوروبیسین; Anthracyclines; Electron beam irradiation; Multidrug resistance; Apoptosis; Acute lymphoblastic leukemiaDAU, daunorubicin; DOX, doxorubicin; EPI, epirubicin; IR, irradiated; NIR, non-irradiated; MDR, multidrug resistance
Review on the binding of anticancer drug doxorubicin with DNA and tRNA: Structural models and antitumor activity
Keywords: دوکسوروبیسین; DOX, Doxorubicin; FTIR, Fourier transform infrared; CD, Circular dichroismDoxorubicin; DNA; tRNA; Intercalation; Groove binding; Conformation; Modeling
Liguzinediol protects against cardiac fibrosis in rats in vivo and in vitro
Keywords: دوکسوروبیسین; Ang II, angiotensin II; CFs, cardiac fibroblasts; CHF, congestive heart failure; DMSO, dimethylsulfoxide; Dox, doxorubicin; ECM, extracellular matrix; Hyp, hydroxyproline; LV, left ventricle; MMPs, matrix matalloproteinases; MTT, 3-(4,5-dimethyl-2-thiazoy
A sensitive high performance liquid chromatography assay for the quantification of doxorubicin associated with DNA in tumor and tissues
Keywords: دوکسوروبیسین; CV%, coefficient of variation; DNA, deoxyribonucleic acid; Dox, doxorubicin; dsDNA, double-stranded DNA; HPLC, high performance liquid chromatography; IV, intravenous; LLOQ, lower limit of quantification; NMR, nuclear magnetic resonance; PK, pharmacokinet
iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy
Keywords: دوکسوروبیسین; Hepatocellular carcinoma; Active targeting; Doxorubicin; Sorafenib; iRGD peptideCl-PARP, Cleaved-Poly ADP ribose polymerase; CI, Combination index; DOX, Doxorubicin; DEE, Drug encapsulation efficiency; DLE, Drug loading efficiency; DLS, Dynamic light scat
Tamoxifen-induced cytotoxicity in breast cancer cells is mediated by glucose-regulated protein 78 (GRP78) via AKT (Thr308) regulation
Keywords: دوکسوروبیسین; GRP78, glucose-regulated protein 78; UPR, unfolded protein response; TAX, paclitaxel; DOX, doxorubicin; 5-FU, 5 fluorouracil; TAM, tamoxifen; ER, estrogen receptorAKT signaling; Breast cancer; Chemoresistance; Endoplasmic reticulum stress; Tamoxifen
Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function
Keywords: دوکسوروبیسین; MDR, Multidrug resistance; P-gp, glycoprotein P; ABC, ATP-binding cassette; PTX, paclitaxel; DOX, doxorubicin; NSCLC, non-small cell lung cancer; CI, combination index; Rho 123, rhodamin123Tangeretin (PubChem CID: 69077); Paclitaxel (PubChem CID: 36314);
Polymer–lipid hybrid nanoparticles synchronize pharmacokinetics of co-encapsulated doxorubicin–mitomycin C and enable their spatiotemporal co-delivery and local bioavailability in breast tumor
Keywords: دوکسوروبیسین; AKR, aldo-keto reductase; AUC, area under the curve; CL, total body clearance; cTnI, cardiac troponin I; DMPLN, doxorubicin and mitomycin C co-loaded polymer–lipid hybrid nanoparticles; DOX, doxorubicin; DOXOL, doxorubicinol; EPR, enhanced permeability an
Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
Keywords: دوکسوروبیسین; ALDH1A1, Aldehyde dehydrogenase 1A1; P-gp, P-glycoprotein; BCRP, breast cancer resistance protein; ATRA, all-trans retinoic acid; DEAB, diethylaminobenzoaldehyde; PAC, paclitaxel; TOP, topotecan; CIS, cisplatin; DOX, doxorubicin; MDR, multiple drug resist
Structure-based optimization leads to the discovery of NSC765844, a highly potent, less toxic and orally efficacious dual PI3K/mTOR inhibitor
Keywords: دوکسوروبیسین; Phosphoinositide 3-kinase (PI3K); Mammalian target of rapamycin (mTOR); Dual inhibitors; AnticancerAIBN, α,α′-azoisobutyronitrile; ATP, adenosine triphosphate; DCM, dichloromethane; DMF, dimethyl formamide; DOX, doxorubicin; GPCR, G-protein-coupled recept
Spectroscopic study on the formation of DNA-Ag clusters and its application in temperature sensitive vehicles of DOX
Keywords: دوکسوروبیسین; DNA-AgNCs, DNA-Ag nanoclusters; Dox, doxorubicin; HIF, hypoxia-inducible factor; N-Pro, total protein from normal cell; H-Pro, total protein from HepG-2DNA-Ag cluster; Aptamer; Vehicle; Dox; Temperature
Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice
Keywords: دوکسوروبیسین; THP, 4′-O-tetrahydropyranyl doxorubicin; DOX, doxorubicin; SP, star polymer; LP, linear polymer; AUC, area under the curve; AOM, azoxymethane; DSS, dextran sodium sulfate; HPMA, N-(2-hydroxyproyl)methacrylamide; EPR, enhanced permeability and retention; P
Lapatinib enhances the cytotoxic effects of doxorubicin in MCF-7 tumorspheres by inhibiting the drug efflux function of ABC transporters
Keywords: دوکسوروبیسین; Lapa, lapatinib; Dox, doxorubicin; ABC, ATP-binding cassette; MRP-1, multidrug resistance-associated protein-1; MDR-1, multidrug resistance protein-1; BCRP, breast cancer resistance protein; HER2, human epidermal growth factor receptor 2; ER, estrogen rec
Cytotoxic and anti-colorectal tumor effects of sulfated saponins from sea cucumber Holothuria moebii
Keywords: دوکسوروبیسین; Holothuria moebii; Sulfated saponin; Desulfated saponin; Inhibition of the proliferation of colorectal cancer cells; Anti-colorectal tumor effectsDAPI, 4,6-diamidino-2-phenylindole; DOX, doxorubicin; FU, fluorouracil; HPLC, high performance liquid chromat
Efficacy Interactions of PEG–DOX–N-acetyl Glucosamine Prodrug Conjugate for Anticancer Therapy
Keywords: دوکسوروبیسین; NAG, N-acetyl glucosamine; DOX, doxorubicin; BSA, bovine serum albumin; CON A, concanavallin A; GLUT, glucose transporter; MALDI-TOF, matrix assisted laser diffraction inductively coupled time of flight; PEG, polyethylene glycolDoxorubicin; N-acetyl gluco
Acquisition of doxorubicin resistance facilitates migrating and invasive potentials of gastric cancer MKN45 cells through up-regulating aldo–keto reductase 1B10
Keywords: دوکسوروبیسین; AKR, aldo–keto reductases; BPS, 3-bromo-5-phenylsalicylic acid; DOX, doxorubicin; DOX-R, doxorubicin-resistant MKN45; DPBS, Dulbecco’s phosphate-buffered saline; ERK, extracellular signal-regulated kinase; HAPE, 3-(4-hydroxy-2-methoxyphenyl)acrylic acid 3
Morphine preconditioning confers cardioprotection in doxorubicin-induced failing rat hearts via ERK/GSK-3β pathway independent of PI3K/Akt
Keywords: دوکسوروبیسین; AAR, area at risk; CPB, cardiopulmonary bypass; CF, coronary flow; DOX, doxorubicin; DMSO, dimethylsulfoxide; EGFR, epidermal growth factor receptor; ERK, extracellular signal regulated kinase; GPCR, G-protein coupled receptor; GSK, glycogen synthase kina
Selection of resistant acute myeloid leukemia SKM-1 and MOLM-13 cells by vincristine-, mitoxantrone- and lenalidomide-induced upregulation of P-glycoprotein activity and downregulation of CD33 cell surface exposure
Keywords: دوکسوروبیسین; AML, acute myeloid leukemia; BCRP, breast cancer resistance protein; CSA, cyclosporine A; DOX, doxorubicin; GAPDH, glyceraldehyde phosphate dehydrogenase; HSP90, heat shock protein 90; KCA, ketoconazole; Len, lenalidomide; LC50, median of lethal concentra
Taurine zinc solid dispersions attenuate doxorubicin-induced hepatotoxicity and cardiotoxicity in rats
Keywords: دوکسوروبیسین; ANT, anthracycline; Cp, crossing point; DOX, doxorubicin; ELISA, enzyme linked immunosorbent assay; HO-1, heme oxygenase-1; JNK, c-Jun N-terminal kinase; MKP1, mitogen-activated protein kinase phosphatase 1; RT-qPCR, real-time quantitative PCR; SDs, solid
Selective targeting of FAK–Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells
Keywords: دوکسوروبیسین; α-Naphthoflavone; Doxorubicin; Chemotherapeutic resistance; Breast cancer; Focal adhesion kinaseANF, alpha-naphthoflavone; BCa, breast cancer; CI, combination index; Cy, cyanine; DMSO, dimethyl sulfoxide; Dox, doxorubicin; FAK, focal adhesion kinase; P-gp
Neuroprotective effects of mGluR II and III activators against staurosporine- and doxorubicin-induced cellular injury in SH-SY5Y cells: New evidence for a mechanism involving inhibition of AIF translocation
Keywords: دوکسوروبیسین; ACPT-I; LY354740; VU0361737; AZ12216052; AMN082; AIFAIF, apoptosis inducing factor; Dox, doxorubicin; FBS, fetal bovine serum; GABA, γ-aminobutyric acid; GPCRs, G-protein-coupled receptors; iGluRs, ionotropic glutamate receptors; LDH, lactate dehydrogenas
Validation and clinical evaluation of a UHPLC method with fluorescence detector for plasma quantification of doxorubicin and doxorubicinol in haematological patients
Keywords: دوکسوروبیسین; DOX, doxorubicin; PK/PD, pharmacokinetic–pharmacodynamic; TDM, therapeutic drug monitoring; DOXol, doxorubicinol; DAU, daunorubicin; LLOQ, lower limit of quantification; CV, coefficient of variation; LQC, low-quality control; MQC, medium-quality control;
In Vitro and In Vivo Study of Gal-OS Self-Assembled Nanoparticles for Liver-Targeting Delivery of Doxorubicin
Keywords: دوکسوروبیسین; Nanoparticles; Drug targeting; Drug delivery systems; Pharmacodynamics; pharmacokinetics; O-carboxymethyl chitosan; liver targeting; tissue distribution; doxorubicin; ASGPR, asialoglycoprotein receptor; DOX, doxorubicin; SNPs, self-assembled nanoparticles
Thymoquinone attenuates Doxorubicin-induced nephrotoxicity in rats: Role of Nrf2 and NOX4
Keywords: دوکسوروبیسین; DOX, Doxorubicin; Nrf2, nuclear factor erythroid 2-related factor 2; TQ, thymoquinone; NOX-4, NADPH oxidase 4Doxorubicin; Nephrotoxicity; Thymoquinone; Nuclear factor erythroid 2-related factor 2; NADPH oxidase 4
SP600125 overcomes antimitotic drug-resistance in cancer cells by increasing apoptosis with independence of P-gp inhibition
Keywords: دوکسوروبیسین; Jnk, c-Jun N-terminal kinase; S.D., Standard deviation; SP, SP600125; PAC, Paclitaxcel; DOC, Docetaxcel; VIB, Vinblastine; COL, Colchicine; DOX, Doxorubicin; MDR, Multi drug-resistance; P-gp, P-glycoprotein; DMSO, Dimethylsulfoxide; FACS, Fluorescence-act
Cardioprotection against doxorubicin by metallothionein Is associated with preservation of mitochondrial biogenesis involving PGC-1α pathway
Keywords: دوکسوروبیسین; DOX, doxorubicin; LVEDD, The end-diastolic dimension of the left ventricle; LVEDS, left-ventricular end systolic diameter; MnSOD, manganese superoxide dismutase; MT, metallothionein; mtDNA, mitochondrial DNA; PGC-1α, peroxisome proliferators–activated rec
L-1416, a novel MDR reversing agent with possible reduced calcium antagonism
Keywords: دوکسوروبیسین; MDR, multidrug resistance; VER, verapamil; VBL, vinblastine; DOX, doxorubicin; VCR, vincristineL-1416; P-gp inhibitor; Tumor therapy; Calcium antagonism
Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft
Keywords: دوکسوروبیسین; AAR, age-adjusted rate; CC-3, cleaved caspase-3; DMEM, Dulbecco's modified Eagle medium; DMSO, dimethyl sulfoxide; Dox, doxorubicin; ECL, enhanced chemiluminescence; EDTA, ethylenediamminetetraacetic acid; ERK, extracellular signal-regulated kinase; FACS,
Synergistic co-delivery of doxorubicin and paclitaxel by porous PLGA microspheres for pulmonary inhalation treatment
Keywords: دوکسوروبیسین; DOX, doxorubicin; PTX, paclitaxel; PLGA, poly(lactic-co-glycolic acid); DMEM, Dulbecco’s modified Eagle medium; PVA, polyvinyl alcohol; ABC, ammonium bicarbonate; MS-D, PLGA microspheres loaded with doxorubicin; MS-P, PLGA microspheres loaded with paclita
Doxorubicin delivery enhanced by electroporation to gastrointestinal adenocarcinoma cells with P-gp overexpression
Keywords: دوکسوروبیسین; EP, electroporation; ECT, electrochemotherapy; DOX, doxorubicin; MDR, multidrug resistance; MDR1, multidrug resistance protein 1; P-gp, permeability glycoprotein; TEM, transmission electron microscopy; CLSM, confocal laser microscopy; rER, rough endoplasm