Keywords: فارماکوژنتیک; Schizophrenia; Cognitive impairments; Kynurenine pathway; Pharmacogenetics; α-7 nicotinic receptor and NMDA receptor
مقالات ISI فارماکوژنتیک (ترجمه نشده)
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Keywords: فارماکوژنتیک; Pharmacogenetics; Alcohol use disorders; Alcohol use; Qualitative
Keywords: فارماکوژنتیک; Salvia miltiorrhiza Bunge (Lamiaceae); Cryptotanshinone; Pharmacogenetics; DDIT3; Unfolded protein response (UPR); Eukaryotic initiation factor (eIF)ALL, acute lymphoblastic leukemia; ATF4, activating transcription factor-4; ATF6, activating transcription
Keywords: فارماکوژنتیک; Tuberculosis; Pharmacogenetics; Adverse drug reactions; Hepatotoxicity; Indigenous
Keywords: فارماکوژنتیک; Clozapine efficacy; Pharmacogenetics; Pharmacodynamic; Serotonergic genes; Weight gain
Keywords: فارماکوژنتیک; Drug metabolizing enzymes; ontogeny; paediatric pharmacology; pharmacodynamics; pharmacogenetics; pharmacokinetics
Keywords: فارماکوژنتیک; Genetics; Pharmacogenetics; Pharmacology; Medications development; Clinical trial; Drug abuse
Keywords: فارماکوژنتیک; Pharmacogenetics; Economic evaluation; Schizophrenia; Diagnostic tests; Cost effectiveness; Stratified medicine
Pharmacogenomics and variations in the risk of toxicity during the consolidation/maintenance phases of the treatment of pediatric B-cell leukemia patients from an admixed population in the Brazilian Amazon
Keywords: فارماکوژنتیک; Pharmacogenetics; Pediatrics; ALL; SLCO1B1; ABCC3;
Variants of FasL and ABCC5 are predictive of outcome after chemotherapy-based treatment in osteosarcoma
Keywords: فارماکوژنتیک; Pharmacogenetics; Osteosarcoma; Variants; FASL; ABCC5;
Pharmacogenetics as Personalized Medicine: Association Investigation of SOD2 rs4880, CYP2C19 rs4244285, and FCGR2A rs1801274 Polymorphisms in a Breast Cancer Population in Iraqi Women
Keywords: فارماکوژنتیک; Breast cancer; CYP2C19; FCGR2A; Pharmacogenetics; SOD2;
Vitamin D pathway genetic variants are able to influence sofosbuvir and its main metabolite pharmacokinetics in HCV mono-infected patients
Keywords: فارماکوژنتیک; Pharmacogenetics; SNP; DAA; Calcitriol; Chronic hepatitis C; Therapeutic drug monitoring;
Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial
Keywords: فارماکوژنتیک; PAR; protease activated receptor; NSTE ACS; non-ST-segment elevation acute coronary syndromes; TRACER; Thrombin Receptor Antagonist for Clinical Event Reduction; Platelets; PAR1; PAR4; Bleeding; Pharmacogenetics;
Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan
Keywords: فارماکوژنتیک; Adverse reactions; Pharmacogenetics; SNP; Cancer; UGT1A1; ABC transporters;
Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients
Keywords: فارماکوژنتیک; ADHD (attention deficit hyperactivity disorder); Methylphenidate; Pharmacogenetics; Norepinephrine/noradrenaline transporter, SLC6A2 (solute carrier family 6, member 2); Promoter polymorphism;
Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients
Keywords: فارماکوژنتیک; CYP3A5 polymorphisms; pharmacogenetics; interstitial fibrosis; tacrolimus; digital image; long-term graft function;
Association of Allelic Interaction of Single Nucleotide Polymorphisms of Influx and Efflux Transporters Genes With Nonhematologic Adverse Events of Docetaxel in Breast Cancer Patients
Keywords: فارماکوژنتیک; ABCB1; ABCC2; Pharmacogenetics; SLCO1B3; SNPs;
ABCB1 C3435T polymorphism is associated with tetrahydrocannabinol blood levels in heavy cannabis users
Keywords: فارماکوژنتیک; ABCB1; P-glycoprotein 1; Cannabis use disorder; Cannabinoids; Pharmacokinetics; Pharmacogenetics;
CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effective
Keywords: فارماکوژنتیک; genetic predisposition; pharmacogenetics; PONV; rs2165870;
Genetic testing as a supporting tool in prescribing psychiatric medication: Design and protocol of the IMPACT study
Keywords: فارماکوژنتیک; Pharmacogenetics; Cytochrome enzymes; Psychiatry; Personalized medicine; Pharmacokinetics;
Pleiotropic genes in psychiatry: Calcium channels and the stress-related FKBP5 gene in antidepressant resistance
Keywords: فارماکوژنتیک; Antidepressants; Treatment-resistant depression; Gene; GWAS; Pharmacogenetics;
Association of MTHF 677TT with adverse drug reactions and RFC G80A with non-response and adverse drug reactions in methotrexate therapy
Keywords: فارماکوژنتیک; Adverse drug reaction; Dihydrofolate reductase; Drug response; Methylenetetrahydrofolate reductase; Pharmacogenetics;
Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy
Keywords: فارماکوژنتیک; Pharmacogenetics; Toxicity; Colorectal cancer; DPYD; Dihydropyrimidine dehydrogenase; Chemotherapy;
Ketamine influences the locus coeruleus norepinephrine network, with a dependency on norepinephrine transporter genotype - a placebo controlled fMRI study
Keywords: فارماکوژنتیک; Ketamine; Locus coeruleus (LC); Norepinephrine transporter (NET); Attention networks; Pharmacogenetics; Major depressive disorder (MDD);
Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation
Keywords: فارماکوژنتیک; Efavirenz (PubChem CID: 64139); 8-Hydroxyefavirenz (PubChem CID: 487643); 7-Ethoxy-4-trifluorometylcoumarin (PubChem CID: 24869840); 7-Hydroxy-4-trifluoromethylcoumarin (PubChem CID: 24862915); Dimanganese decacarbonyl (PubChem CID: 517769); Sodium hydros
Results of ASERTAA, a Randomized Prospective Crossover Pharmacogenetic Study of Immediate-Release Versus Extended-Release Tacrolimus in African American Kidney Transplant Recipients
Keywords: فارماکوژنتیک; Immunosuppression; tacrolimus; kidney transplantation; pharmacogenetics; tacrolimus dosing; randomized clinical trial; African American ancestry; genetic differences; CYP3A5 allele; pharmacokinetics; drug absorption; genotype;
Farmacogenética de reacciones adversas a fármacos antiepilépticos
Keywords: فارماکوژنتیک; Farmacogenética; Reacciones adversas a medicamentos; Fármacos antiepilépticos; CYP2C9; ABCC2; AntÃgeno leucocitario humano (HLA); Pharmacogenetics; Adverse drug reactions; Antiepileptic drugs; CYP2C9; ABCC2; Human leukocyte antigen (HLA);
The HLA-B*15:02 polymorphism and Tegretol®-induced serious cutaneous reactions in epilepsy: An updated systematic review and meta-analysis
Keywords: فارماکوژنتیک; ADRs; adverse drug reactions; cADRs; cutaneous adverse drug reactions; CBZ; carbamazepine; CI; confidence interval; DNA; deoxyribonucleic acid; DRESS; drug reaction with eosinophilia and systemic symptoms; GABRA1; gamma-aminobutyric acid type A receptor a
Pharmacogenomics signature: A novel strategy on the individual differences in drug response
Keywords: فارماکوژنتیک; Pharmacogenomics; Pharmacogenetics; Pharmacogenomics signature;
An interdigitated electrode biosensor platform for rapid HLA-B*15:02 genotyping for prevention of drug hypersensitivity
Keywords: فارماکوژنتیک; Loop mediated isothermal amplification; Interdigitated electrodes; Impedance sensor; Nucleic acid sensor; Point-of-care diagnostics; Pharmacogenetics;
CHST3 and CHST13 polymorphisms as predictors of bosentan-induced liver toxicity in Japanese patients with pulmonary arterial hypertension
Keywords: فارماکوژنتیک; Bosentan; Pulmonary arterial hypertension; Proteoglycan; DMET; Asian; Drug metabolism enzymes and transporters; Affimetrix; Pharmacogenomics; Pharmacogenetics;
Genetics of tailored medicine: Focus on CNS drugs
Keywords: فارماکوژنتیک; Cytochrome P450; CYP; Pharmacogenetics; Tailored medicine;
Population pharmacokinetics of valproic acid in epileptic children: Effects of clinical and genetic factors
Keywords: فارماکوژنتیک; Valproic acid; Population pharmacokinetics; LEPR; Pharmacogenetics; Epileptic children;
Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics
Keywords: فارماکوژنتیک; ADH; alcohol dehydrogenase; CDC; Centers for Disease Control and Prevention; CYP; cytochrome P450; del; deletion; EDDP; 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine; EM; extensive metabolizer; EMDP; 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline; FDA; Food and
Association of regulatory TPH2 polymorphisms with higher reduction in depressive symptoms in children and adolescents treated with fluoxetine
Keywords: فارماکوژنتیک; Fluoxetine; Pharmacogenetics; Children; TPH2; Polymorphism; rs34517220;
Polymorphism of the SNAP25 gene is associated with symptom improvement in schizophrenic patients treated with amisulpride
Keywords: فارماکوژنتیک; Treatment response; Antipsychotics; Amisulpride; Schizophrenia; SNAP25 gene; Pharmacogenetics;
Lack of genetic association between OCT1, ABCB1, and UGT2B7 variants and morphine pharmacokinetics
Keywords: فارماکوژنتیک; Morphine; Interindividual variability; Pharmacokinetics; Pharmacogenetics; Healthy volunteers;
NadwrażliwoÅÄ na leki - rekomendacje wobec praktyki
Keywords: فارماکوژنتیک; alergia na leki; nadwrażliwoÅÄ na leki; zalecenia; klasyfikacja; farmakogenetyka; prewencja; Drug allergy; Hypersensitivity to drugs; Recommendations; Classification; Pharmacogenetics; Prevention;
Epigenetic and genetic variants in the HTR1B gene and clinical improvement in children and adolescents treated with fluoxetine
Keywords: فارماکوژنتیک; Fluoxetine; Pharmacogenetics; Methylation; Children; HTR1B; Polymorphism;
Influence of MDR1 and CYP3A5 genetic polymorphisms on trough levels and therapeutic response of imatinib in newly diagnosed patients with chronic myeloid leukemia
Keywords: فارماکوژنتیک; Pharmacogenetics; P-glycoprotein; Imatinib resistance; Single nucleotide polymorphisms; Personalized medicine; Tyrosine kinase inhibitor;
African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development
Keywords: فارماکوژنتیک; Pharmacogenetics; CYP450; Genetic diversity; Drug metabolism; Africa; Drug development;
The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients
Keywords: فارماکوژنتیک; AR-V7; Exosomes; Digital droplet PCR; Prostate cancer; Pharmacogenetics; Resistance; Hormonal therapy;
Pharmacogenetics of antidepressant drugs: State of the art and clinical implementation - recommendations from the French National Network of Pharmacogenetics
Keywords: فارماکوژنتیک; Pharmacogenetics; Antidepressant drugs; Psychiatry; CYP2C19; CYP2D6;
Intuitive pharmacogenetic dosing of risperidone according to CYP2D6 phenotype extrapolated from genotype in a cohort of first episode psychosis patients
Keywords: فارماکوژنتیک; Pharmacogenetics; Pharmacokinetics; Antipsychotic; CYP2D6;
Original ResearchPharmacogenetic association of MBL2 and CD95 polymorphisms with grade 3 infection following adjuvant therapy for breast cancer with doxorubicin and cyclophosphamide
Keywords: فارماکوژنتیک; Cancer chemotherapy drugs; Cyclophosphamide; Doxorubicin; Pharmacogenetics; MBL2; CD95; Infection;
Gulp1 is associated with the pharmacokinetics of PEGylated liposomal doxorubicin (PLD) in inbred mouse strains
Keywords: فارماکوژنتیک; Nanoparticles; PLD; Gulp1; Pharmacokinetics; Pharmacogenetics;
Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking
Keywords: فارماکوژنتیک; K+ channels; Alcohol use disorder; Pharmacogenetics; BXD mice; Prefrontal cortex; Nucleus accumbens;
Genome-wide association study of treatment response to venlafaxine XR in generalized anxiety disorder
Keywords: فارماکوژنتیک; Pharmacogenetics; Generalized anxiety disorder; Venlafaxine XR;
Intestinal Drug Interactions Mediated by OATPs: A Systematic Review of Preclinical and Clinical Findings
Keywords: فارماکوژنتیک; drug interaction; inhibition; transporter; organic anion-transporting polypeptide transporters; intestinal absorption; polymorphism; AUC; area under the plasma concentration-time curve; DDIs; drug-drug interactions; EMA; European Medicines Agency; FDA
CYP2C9 Genotypes Modify Benzodiazepine-Related Fall Risk: Original Results From Three Studies With Meta-Analysis
Keywords: فارماکوژنتیک; Benzodiazepines; falls; CYP2C9; pharmacogenetics; meta-analyses;