Aripiprazole brain concentration is altered in P-glycoprotein deficient mice
Keywords: سد خونی مغزی; Aripiprazole; Knockout mouse; P-glycoprotein; Transport; Blood brain barrier
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Pathophysiology and treatment of traumatic brain edema
Keywords: سد خونی مغزی; blood brain barrier; brain edema; head injury; intracranial pressure;
Transport of gatifloxacin involves Na+/Ca2+ exchange and excludes P-glycoprotein and multidrug resistance associated-proteins in primary cultured rat brain endothelial cells
Keywords: سد خونی مغزی; Gatifloxacin; Blood brain barrier; Ca2+ channel; Na+/Ca2+ exchange; Rat brain microvessel endothelial cells
Chitosan solutions and particles: Evaluation of their permeation enhancing potential on MDCK cells used as blood brain barrier model
Keywords: سد خونی مغزی; Chitosan; MDCK; Permeation; Blood brain barrier; Nanoparticles
IL-15 independent maintenance of virus-specific CD8+ T cells in the CNS during chronic infection
Keywords: سد خونی مغزی; BBB; blood brain barrier; CLN; cervical lymph nodes; i.c.; intracerebral; JHMV; JHM strain of mouse hepatitis virus; p.i.; post infection; SC; spinal cord; TCM; central memory T cells; TEM; effector memory T cells.; Cytokines; T cells; Cytotoxic; Neuroimm
Viral nanoparticles associate with regions of inflammation and blood brain barrier disruption during CNS infection
Keywords: سد خونی مغزی; CPMV; Blood brain barrier; Nanoparticles; Microglial cells; Central nervous system; Targeting
α4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions
Keywords: سد خونی مغزی; Chemokines; α4 integrin; Leukocyte; Blood brain barrier; Adhesion; Shear stress; Multiple sclerosis
The m.3243A>G mtDNA mutation is pathogenic in an in vitro model of the human blood brain barrier
Keywords: سد خونی مغزی; Cell culture model; Blood brain barrier; MELAS; Stroke; Endothelial cells; Astrocytes
Research ReportThyrotropin-releasing hormone d,l polylactide nanoparticles (TRH-NPs) protect against glutamate toxicity in vitro and kindling development in vivo
Keywords: سد خونی مغزی; AD; afterdischarge; ADD; afterdischarge duration; BBB; blood brain barrier; BFGF; basic fibroblast growth factor; d,l-PLA; poly (l-lactic acid-d-lactic acid); EEG; electroencephalography; Glu; glutamate; NP; nanoparticle; HBSS; Hanks buffered salt solutio
Synthesis, radiolabeling and biological evaluation of a neutral tripeptide and its derivatives for potential nuclear medicine applications
Keywords: سد خونی مغزی; ACM; acetoamidomethyl; 99mTc; metastable technetium (radioactive); BBB; blood brain barrier; Cys; cysteine; ECD; ethyl cysteinate dimmer; Phe; phenylalanine; PPB; plasma protein binding; Peptide; 99mTc-labeled peptides; Brain imaging;
The Effects of Riluzole on Neurological, Brain Biochemical, and Histological Changes in Early and Late Term of Sepsis in Rats
Keywords: سد خونی مغزی; riluzole; glutamate; sepsis; encephalopathy; blood brain barrier; antioxidant; neuroprotective; MDA; glutathione
Reproductive age-related changes in the blood brain barrier: Expression of IgG and tight junction proteins
Keywords: سد خونی مغزی; Blood brain barrier; IgG; Microvessels; Occludin; Claudin-5; Estrogen; Menopause; Hippocampus
Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson's disease
Keywords: سد خونی مغزی; Blood brain barrier; Mesenchymal stem cells; MPTP; Neuroinflammation; Parkinson's disease
MMP-9 gene silencing by a quantum dot–siRNA nanoplex delivery to maintain the integrity of the blood brain barrier
Keywords: سد خونی مغزی; Nanotechnology; siRNA; Nanoplex; Blood brain barrier; Matrix metalloproteinases; MMP-9; Quantum dot; CNS
Repetitive/temporal hypoxia increased P-glycoprotein expression in cultured rat brain microvascular endothelial cells in vitro
Keywords: سد خونی مغزی; P-glycoprotein; Hypoxia; Rat brain microvasclular endothelial cells; Blood brain barrier
Pharmacokinetics of fructose-1,6-diphosphate after intraperitoneal and oral administration to adult rats
Keywords: سد خونی مغزی; Blood brain barrier; Fructose-1,6-bisphosphate; Fructose-1,6-diphosphate; Pharmacokinetics; Rat
Injury of the Blood Brain Barrier and Up-Regulation of ICAM-1 in Polymicrobial Sepsis 1
Keywords: سد خونی مغزی; septic encephalopathy; albumin; blood brain barrier; ICAM-1; PECAM-1
Effects of Transcranial Ultrasound and Intravenous Microbubbles on Blood Brain Barrier Permeability in a Large Animal Model
Keywords: سد خونی مغزی; Ultrasound; Microbubbles; Blood brain barrier;
Characterization of apolipoprotein A-IV in brain areas involved in energy homeostasis
Keywords: سد خونی مغزی; Apolipoproteins; Immunohistochemistry; Blood brain barrier; Neuropeptides
Hypothermic Circulatory Arrest Increases Permeability of the Blood Brain Barrier in Watershed Areas
Keywords: سد خونی مغزی; ANOVA; analysis of variance; BBB; blood brain barrier; CPB; cardiopulmonary bypass; EBD; Evans blue dye; FF; full flow; HCA; hypothermic circulatory arrest; LF; low flow; MAP; mean arterial pressure; PBS; phosphate-buffered saline; PCO2; partial carbon di
Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan
Keywords: سد خونی مغزی; BBB; blood brain barrier; 5-HT; serotonin; DCVs; dense core vesicles; SC; subcutaneous; IT; intrathecal; 5-HT1D-IR; 5-HT1D receptor immunoreactivity; Migraine; Headache; Inflammation; Serotonin; Sumatriptan; Intrathecal; Blood brain barrier;
DTI derived indices correlate with immunohistochemistry obtained matrix metalloproteinase (MMP-9) expression in cellular fraction of brain tuberculoma
Keywords: سد خونی مغزی; Brain tuberculoma; Matrix metalloproteinase; Extracellular matrix; Blood brain barrier; Diffusion tensor imaging
Angiopoietin-like protein 1 decreases blood brain barrier damage and edema following focal cerebral ischemia in mice
Keywords: سد خونی مغزی; Angptl1; Stroke; Infarction; Edema; Blood brain barrier; Transgenic mice
Research ReportTGFβ2-induced changes in LRP-1/TβR-V and the impact on lysosomal Aβ uptake and neurotoxicity
Keywords: سد خونی مغزی; A2M; Alpha 2 macroglobulin; Aβ; Amyloid beta protein; AD; Alzheimer's disease; ApoE; Apolipoprotein E; APP; Amyloid precursor protein; BBB; Blood brain barrier; ir; immunoreactivity; LAMP1; Lysosomal-associated membrane protein 1; LRP; Low-density lipopr
Multiple expression of matrix metalloproteinases in murine neurocysticercosis: Implications for leukocyte migration through multiple central nervous system barriers
Keywords: سد خونی مغزی; Neurocysticercosis; Matrix metalloproteinases; Blood brain barrier; Blood–cerebrospinal fluid barrier; Ventricle; Ependyma
Methamphetamine alters blood brain barrier permeability via the modulation of tight junction expression: Implication for HIV-1 neuropathogenesis in the context of drug abuse
Keywords: سد خونی مغزی; HIV-1; human immunodeficiency virus-1; ADC; AIDS dementia complex; BBB; Blood Brain Barrier; BMVEC; brain microvascular endothelial cells; CNS; Central nervous system; DEPC; diethyl pyrocarbonate; FITC; Fluorescein; HAD; HIV-1 associated dementia; IL1-β;
Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood–brain barrier opening in rodents: Differences in response based on strains and solvents
Keywords: سد خونی مغزی; Neuroinflammation; Lipopolysaccharide; Blood brain barrier; Matrix metalloproteinase; Matrix metalloproteinase inhibitor; Mice; Rat
Sex differences in modulating blood brain barrier permeability by NO in pentylenetetrazol-induced epileptic seizures
Keywords: سد خونی مغزی; l-NAME; SNP; Blood brain barrier; Sex differences
Ability of carbazole salts, inhibitors of Alzheimer β-amyloid fibril formation, to cross cellular membranes
Keywords: سد خونی مغزی; Alzheimer; Blood brain barrier; β-amyloid; Inhibitor; Carbazole; P-glycoprotein; MRP1; Membrane
Retro-convection enhanced delivery to increase blood to brain transfer of macromolecules
Keywords: سد خونی مغزی; BBB; blood brain barrier; CED; convection enhanced delivery; EB; Evans blue; H&E; hematoxylin and eosin; ISF; interstitial fluid; MWCO; molecular weight cutoff; PBS; phosphate-buffered saline; PEG; polyethylene glycol; PVP; polyvinylpyrrolidone; R-CED; re
The interferon-induced expression of APOBEC3G in human blood–brain barrier exerts a potent intrinsic immunity to block HIV-1 entry to central nervous system
Keywords: سد خونی مغزی; APOBEC3G; HIV-1; Interferon; Blood brain barrier; Brain microvascular endothelial cellsHIV-1, human immunodeficiency virus type 1; BMVECs, brain microvascular endothelial cells; CNS, central nervous system; BBB, blood–brain barrier; siRNA, short-interferi
Enaminones: Exploring Additional Therapeutic Activities
Keywords: سد خونی مغزی; blood brain barrier; crystal structure; molecular modeling; multidrug resistance; PSAR; Pâglycoprotein; efflux pumps; log P;
Pharmacokinetics and brain uptake of lactoferrin in rats
Keywords: سد خونی مغزی; Lactoferrin; Pharmacokinetics; Blood brain barrier; Transport
Utilidad del análisis del lÃquido cefalorraquÃdeo para el estudio de las deficiencias del metabolismo de neurotransmisores y pterinas y del transporte de glucosa y folato a través de la barrera hematoencefálica
Keywords: سد خونی مغزی; Neurotransmisores; Dopamina; Serotonina; Pterinas; LÃquido cefalorraquÃdeo; Transporte de glucosa; Transporte de folato; Barrera hematoencefálica; Neurotransmitters; Dopamin; Serotonine; Pterins; Cerebrospinal fluid; Glucose transport; Folate transport
Cerebrovascular Dynamics and Vascular Endothelial Growth Factor in Acute Mountain Sickness
Keywords: سد خونی مغزی; dynamic vascular analysis; transcranial Doppler ultrasound; acute mountain sickness; endothelial dysfunction; blood brain barrier; vascular endothelial growth factor; altitude;
Brain Iron Metabolism
Keywords: سد خونی مغزی; blood brain barrier; transferrin receptor; ferroportin; GPI-linked ceruloplasmin; Parkinson disease
Influence of particle size on transport of methotrexate across blood brain barrier by polysorbate 80-coated polybutylcyanoacrylate nanoparticles
Keywords: سد خونی مغزی; Polybutylcyanoacrylate; Methotrexate; Nanoparticles; Blood brain barrier
Apoptosis inhibition in ischemic brain by intraperitoneal PTD-BIR3-RING (XIAP)
Keywords: سد خونی مغزی; Apoptosis; Blood brain barrier; Ischemia; Protein transduction; XIAPAntp HD, antennapedia aomeodomain of Drosophila; BIRs, baculoviral-inhibitor of apoptosis repeats; CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; PTDs, protein transduc
Temporal expression of IL-1β protein and mRNA in the brain after systemic LPS injection is affected by age and estrogen
Keywords: سد خونی مغزی; Olfactory bulb; Blood brain barrier; Pituitary; Reproductive senescence
A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data
Keywords: سد خونی مغزی; blood brain barrier; structure activity relationship (SAR); multivariate analysis; QSAR; linear free energy relationship; hydrogen bonding;
Hypernatrémie contrôlée
Keywords: سد خونی مغزی; Osmolarité cérébrale; Sérum salé hypertonique; Barrière hématoencéphalique; Pression intracrânienne; Traumatisme crânien; MannitolBrain osmolarity; Hypertonic saline; Blood brain barrier; Intracranial pressure; Traumatic brain injury; Mannitol
A preliminary neuropathological study of Japanese encephalitis in humans and a mouse model
Keywords: سد خونی مغزی; Arbovirus; Japanese encephalitis; Zoonosis; Blood brain barrier;
Breakdown of the blood brain barrier and blood–cerebrospinal fluid barrier is associated with differential leukocyte migration in distinct compartments of the CNS during the course of murine NCC
Keywords: سد خونی مغزی; Blood brain barrier; Blood–cerebrospinal fluid barrier; Neurocysticercosis; Mesocestoides corti; Central nervous system
Cerebral kinetics of oxycodone in conscious sheep
Keywords: سد خونی مغزی; oxycodone; pharmacokinetics; distribution; blood brain barrier; blood flow; physiological model; sheep;
Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice
Keywords: سد خونی مغزی; Cerebral malaria; Apoptosis; Neural apoptosis; Metallothionein; Blood brain barrier; Inflammatory responses; Infection; Plasmodium berghei
Feeding effects of melanocortin ligands-A historical perspective
Keywords: سد خونی مغزی; ACTH; adrenocorticotropic hormone; AGRP; agouti-related protein; Anc; amino-2-naphtylcarboxylic acid; ARC; arcuate nucleus of the hypothalamus; BBB; blood brain barrier; DMH; dorsomedial nucleus of the hypothalamus; icv; intracerebroventricularly; ip; int
Drug Transport to Brain with Targeted Nanoparticles
Keywords: سد خونی مغزی; Nanoparticle; immunonanoparticle; brain targeting; blood brain barrier; transcytosis; PEG;
Macrophages and HIV-1: dangerous liaisons
Keywords: سد خونی مغزی; AMM; activated macrophages and microglial cells; APC; antigen-presenting cells; BBB; blood brain barrier; CAF; CD8 antiviral factor; C/EBPβ; CCAAT/enhancer binding protein β; CNF; central nervous system; Cppt; central polypurine tract; EAAT; excitatory
Oxidative stress during the chronic phase after stroke
Keywords: سد خونی مغزی; AA; arachidonic acid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; BBB; blood brain barrier; CNS; central nervous system; CSF; cerebrospinal fluid; CRP; C-reactive protein; DNA; deoxyribonucleic acid; EAA; excitatory amino acids; GSH; reduced