Keywords: سازمان غذا و دارو (آمریکا); Food ingredients; GRAS; Notices; Critical review; FDA
مقالات ISI سازمان غذا و دارو (آمریکا) (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: سازمان غذا و دارو (آمریکا); FDA; fetal risk; lactation; medication labeling; pregnancy
Investigation of the effect of plasma albumin levels on regorafenib-induced hepatotoxicity using a validated liquid chromatography-tandem mass spectrometry method
Keywords: سازمان غذا و دارو (آمریکا); ACN; acetonitrile; CE; collision energy; CS; calibration standards; CXP; collision cell exit potential; ED; equilibrium dialysis; EP; entrance potential; ESI; electrospray ionization; DP; declustering potential; FDA; US Food and Drug Administration; IS; i
ReviewConcerns with beta2-agonists in pediatric asthma - a clinical perspective
Keywords: سازمان غذا و دارو (آمریکا); β2-agonists; Tolerance; Asthma; Genetic polymorphisms; cAMP; cyclic adenosine monophosphate; BARGE; Beta Adrenergic Response by Genotype; β2AR; β2-adrenoreceptor; BHR; bronchial hyperresponsiveness; EIB; exercise induced bronchoconstriction; FDA; food
Original ArticlesChemical Leukoderma Associated with Methylphenidate Transdermal System: Data From the US Food and Drug Administration Adverse Event Reporting System
Keywords: سازمان غذا و دارو (آمریکا); attention deficit hyperactivity disorder; depigmentation; hypopigmentation; vitiligo; skin discoloration; ADHD; Attention deficit-hyperactivity disorder; FAERS; FDA Adverse Event Reporting System; FDA; Food and Drug Administration; MedDRA; Medical Diction
Development and validation of a LC-MS/MS assay for quantification of cisplatin in rat plasma and urine
Keywords: سازمان غذا و دارو (آمریکا); DPCPX; 8-cyclopentyl-1,3-dipropylxanthine; CS; calibrationstandards; DDTC; diethyldithiocarbamate; ESIEl; ectrospray ionization; FDA; Food and Drug Administration; HPLC; High performance liquid chromatography; ICP-MS; induction coupled mass spectrometry;
Evaluation of the virus clearance capacity and robustness of the manufacturing process for the recombinant factor VIII protein, turoctocog alfa
Keywords: سازمان غذا و دارو (آمریکا); Turoctocog alfa; Manufacture; Virus clearance; rFVIII; Virus safety; Virus clearance evaluation; BEV; Bovine enterovirus; CHO; Chinese hamster ovary; EMA; European Medicines Agency; eMuLV; Ecotropic murine leukaemia virus; FDA; US Food and Drug Administra
Heme iron, non-heme iron, and mineral content of blood clams (Anadara spp.) compared to Manila clams (V. philippinarum), Pacific oysters (C. gigas), and beef liver (B. taurus)
Keywords: سازمان غذا و دارو (آمریکا); DV; Daily Value; DM; dry matter; EP; edible portion; FDA; United States Food and Drug Administration; PTMI; Provisional Tolerable Monthly Intake; PTWI; Provisional Tolerable Weekly Intake; RACC; reference amount customarily consumed; RDA; Recommended Diet
Searching for animal models and potential target species for emerging pathogens: Experience gained from Middle East respiratory syndrome (MERS) coronavirus
Keywords: سازمان غذا و دارو (آمریکا); Animal model; Coronavirus (CoV); Emerging pathogen; Middle East respiratory syndrome (MERS); Reservoir; BSL; biosafety level; DPP4; dipeptidyl peptidase-4; FDA; Food and Drug Administration; HCoV; human coronaviruses; hDPP4; human dipeptidyl peptidase-4;
Original ArticleKinase Activity in Recurring Primary Skull Base Chordomas and Chondrosarcomas: Identification of Novel Pathways of Oncogenesis and Potential Drug Targets
Keywords: سازمان غذا و دارو (آمریکا); Chondrosarcoma; Chordoma; Kinase; Proteome; FDA; U.S. Food and Drug Administration; iTRAQ; Isobaric tags for relative and absolute quantitation; MS; Mass spectroscopy;
Development and validation of a highly sensitive LC-ESI-MS/MS method for estimation of IIIM-MCD-211, a novel nitrofuranyl methyl piperazine derivative with potential activity against tuberculosis: Application to drug development
Keywords: سازمان غذا و دارو (آمریکا); LC; liquid chromatography; MS; mass spectrometry; MS/MS; tandem mass spectrometry; FDA; Food and Drug Administration; IS; internal standard; ESI; electrospray ionization; MRM; multiple reaction monitoring; IV; intravenous; TB; tuberculosis; MTB; Mycobacte
PerspectivePatients come from populations and populations contain patients. A two-stage scientific and ethics review: The next adaptation for single institutional review boards
Keywords: سازمان غذا و دارو (آمریکا); Alzheimer's; Dementia; Ethics; Clinical trial; IRB; FDA; EMEA; Therapeutic; Intervention; Prevention; Treatment;
Biomimetic 3D printed scaffolds for meniscus tissue engineering
Keywords: سازمان غذا و دارو (آمریکا); COV; Coefficient of Variation; ECM; Extracellular matrix; EM; Equilibrium modulus; FDA; Food and Drug Administration; FS; Fibre spacing; OA; Osteoarthritis; PCL; Polycaprolactone; Meniscus; Tissue engineering; Biomimicry; 3D printing; Scaffolds; Regenerat
Deciphering molecular properties and docking studies of hepatitis C and non-hepatitis C antiviral inhibitors - A computational approach
Keywords: سازمان غذا و دارو (آمریکا); 2D; Two-Dimensional; 3D; Three-Dimensional; DAAs; Direct Acting Antivirals; FDA; Food and Drug Administration; HCV; Hepatitis C Virus; HBV; Hepatitis B Virus; HCMV; Human Cytomegalo Virus; HIV; Human Immunodeficiency Virus; HSV; Herpes Simplex Virus; Inf
Recent trends in ZikV research: A step away from cure
Keywords: سازمان غذا و دارو (آمریکا); ZikV; GBS; Microcephaly; DNA vaccination; FDA; MPA DNA; ZPIV; LAIV; AGS-v;
One and done: Reasons principal investigators conduct only one FDA-regulated drug trial
Keywords: سازمان غذا و دارو (آمریکا); FDA; Drug trials; Investigator turnover; Attrition; Physician-investigator;
Original ArticleThe second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model
Keywords: سازمان غذا و دارو (آمریکا); Neuroblastoma; ALK inhibitor; Alectinib; PI3K/Akt/mTOR; Apoptosis; NB; neuroblastoma; ALK; anaplastic lymphoma kinase; WT; wild type; dox; doxorubicin; DMSO; dimethyl sulfoxide; FDA; Food and Drug Administration; ALCL; anaplastic large cell lymphoma; NSCL
Research paperIn-line monitoring of multi-layered film-coating on pellets using Raman spectroscopy by MCR and PLS analyses
Keywords: سازمان غذا و دارو (آمریکا); PAT; process analytical technology; EMA; European medicines agency; FDA; food and drug administration; ICH; international conference for harmonization of technical requirements for registration of pharmaceuticals for human use; PLS; partial least squares;
Pituitary adenylate cyclase-activating polypeptide (PACAP) protects against mitoxantrone-induced cardiac injury in mice
Keywords: سازمان غذا و دارو (آمریکا); d; diastole; EF; ejection fraction; FDA; Food and Drug Administration; FS; fractional shortening; i.p.; intraperitoneal; IVS; intraventricular septum; LV; left ventricle; LVID; internal diameter of the left ventricle; LVPW; thickness of the posterior wall
Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine
Keywords: سازمان غذا و دارو (آمریکا); ACN; acetonitrile; BER; base excision repair; C.V.; coefficient of variation; DMSO; dimethylsulfoxide; DSB; double strand break; EMA; European Medicine Agency; FDA; Food and Drug Administration; GLP; Good Laboratory Practice; HRR; homologous recombination
Gastric toxicity involving alterations of gastritis-related protein expression in mice following long-term exposure to nano TiO2
Keywords: سازمان غذا و دارو (آمریکا); BW; body weight; COX-2; cyclooxygenase-2; ELISA; Enzyme Linked Immunosorbent Assay; FDA; Food and Drug Administration; HE; hematoxylin and eosin; ICP-MS; inductively coupled plasma-mass spectrometry; IKK; IκB kinase; IL; interleukin; HPMC; hydroxypropylm
ReviewCurrent and cutting-edge interventions for the treatment of obese patients
Keywords: سازمان غذا و دارو (آمریکا); BEAT Obesity; Bariatric Embolization of Arteries for the Treatment of Obesity; BMI; body mass index; CDC; Centers for Disease Control and Prevention; EWL; excess weight loss; FDA; Food and Drug Administration; GET LEAN; Gastric Artery Embolization Trial f
Research articleDifferent roles of glutathione in copper and zinc chelation in Brassica napus roots
Keywords: سازمان غذا و دارو (آمریکا); Copper; Zinc; Heavy metal toxicity; Glutathione; Chelation; EDTA; ethylenediaminetetraacetic acid; FDA; fluorescein diacetate; GSH; glutathione; GSSG; oxidized glutathione; 2-VP; 2-vinylpyridine;
FTY720 (Fingolimod) reverses α-synuclein-induced downregulation of brain-derived neurotrophic factor mRNA in OLN-93 oligodendroglial cells
Keywords: سازمان غذا و دارو (آمریکا); Anti-inflammatory; Glioprotective; Multiple system atrophy; Neuroprotective; Restorative effects; AcH3; acetylated histone 3; aSyn; α-synuclein; BDNF; brain-derived neurotrophic factor; bp; base pair; DLB; Dementia with Lewy Bodies; FDA; Food and Drug Ad
UBX domain-containing proteins are involved in lipid homeostasis and stress responses in Pichia pastoris
Keywords: سازمان غذا و دارو (آمریکا); ALA; α-linolenic acid; CHX; cycloheximide; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; ER; endoplasmic reticulum; ERAD; endoplasmic reticulum associated protein degradation; FDA; fluorescein diacetate; GO; gene ontology; KEGG; Kyoto Encyclopedia of
Cryopreservation of olive somatic embryos using the droplet-vitrification method: The importance of explant culture conditions
Keywords: سازمان غذا و دارو (آمریکا); Olive; Cryopreservation; Droplet-vitrification; Somatic embryos; Histological analysis; ECO; olive cyclic embryogenesis medium; FDA; fluorescein diacetate; LS; loading solution; LSD; least significant difference; PAS; periodic acid-Schiff; PVS2; plant v
Assessment of antimicrobial effects of food contact materials containing silver on growth of Salmonella Typhimurium
Keywords: سازمان غذا و دارو (آمریکا); Silver; Food contact material; Bacteria; Growth; Salmonella; Ag-containers; Silver infused containers; AgNP; Silver Nanoparticles; CFU; Colony-Forming Units; EPA; Environmental Protection Agency; FDA; Food and Drug Administration; FCM; Food Contact Materi
Original Research ArticleMetabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties
Keywords: سازمان غذا و دارو (آمریکا); CHI; chalcone isomerase; CHS; chalcone synthase; CH3H; chalcone 3-hydroxylase; CPR; cytochrome P450 reductase; CYP; cytochrome P450; C4H; cinnamate 4-hydroxylase; DBR; double bond reductase; DHC; dihydrochalcone; EMA; European Medicine Agency; FDA; Food a
Cell-type dependent response to photodynamic treatment in 3D collagen cell cultures
Keywords: سازمان غذا و دارو (آمریکا); 2D; two-dimensional; 3D; three-dimensional; ALA; aminolevulinic acid; AO; Acridine Orange; CMO; CellMask Orange; ECM; extracellular matrix; FDA; Food and Drug Administration agency; PDT; photodynamic therapy; PpIX; protoporphyrin IX; UV; ultraviolet; VIS;
Original Research ArticleA novel method for the quantification of long-chain omega-3 polyunsaturated fatty acids (PUFA) in gummy dietary supplements
Keywords: سازمان غذا و دارو (آمریکا); AOCS; American Oil Chemists' Society; CL; confidence limit; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; FAME; fatty acid methyl ester; FDA; United StatesFood and Drug Administration; GC-FID; gas chromatography with flame ionization detection;
Osteotropic nanoscale drug delivery systems based on small molecule bone-targeting moieties
Keywords: سازمان غذا و دارو (آمریکا); Musculoskeletal tissue; Small molecules; Targeted drug delivery; Nanomedicine; FDA; Food and Drug Administration; SERMs; selective estrogen receptor modulators; NP; nanoparticle; PEG; polyethylene glycol; HA; hydroxyapatite; ALD; alendronate; PLGA; poly(l
Research reportTwo cholinesterase inhibitors trigger dissimilar effects on behavior and body weight in C57BL/6 mice: The case of chlorpyrifos and rivastigmine
Keywords: سازمان غذا و دارو (آمریکا); ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; BM; Barnes maze; ChE; cholinesterase; CPF; chlorpyrifos; FDA; Food and Drug Administration; MWM; Morris water maze; OF; open field; OP; organophosphate; RIV; rivastigmine; Cholines
Research paperThe dispersion releaser technology is an effective method for testing drug release from nanosized drug carriers
Keywords: سازمان غذا و دارو (آمریکا); API; active pharmaceutical ingredient; BSA; bovine serum albumin; CAR; compartmental accumulation ratio; DB; dialysis bag; DLS; dynamic light scattering; DR; dispersion releaser; FDA; Food and Drug Administration; HPLC; high-performance liquid chromatogra
Salvianolic Acids for Injection (SAFI) suppresses inflammatory responses in activated microglia to attenuate brain damage in focal cerebral ischemia
Keywords: سازمان غذا و دارو (آمریکا); SAFI; Salvianolic Acids for Injection; MCAO; Middle cerebral artery occlusion; TLR4; Toll like receptor 4; NF-κB; nuclear factor-κB; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; I/R; ischemia/reperfusion; IL; interleukin; FDA; Food and Dru
Bioprocess integration for human mesenchymal stem cells: From up to downstream processing scale-up to cell proteome characterization
Keywords: سازمان غذا و دارو (آمریکا); AT-MSC; adipose tissue-derived hMSC; BM-MSC; bone marrow-derived hMSC; BR; bioreactor(s); DPBS; dulbecco's phosphate-buffered saline; DSP; downstream processing; FDA; fluorescein diacetate; FDR; false discovery rate; FSC; flat sheet cassettes; HF; hollo
Hybrid polymeric matrices for oral modified release of Desvenlafaxine succinate tablets
Keywords: سازمان غذا و دارو (آمریکا); Desvenlafaxine succinate; Controlled release matrix; Apparent permeability coefficient; Everted sac; Papp; apparent permeability coefficient; DSV; Desvenlafaxine succinate; DSC; differential scanning calorimetry; FDA; Food and Drug Administration; HPMC; h
Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study
Keywords: سازمان غذا و دارو (آمریکا); Furan; Tumorigenicity; Cholangiocarcinoma; Cholangiofibrosis; Rats; Bioassay; BMD; benchmark dose; BMDL; lower limit of benchmark dose; BW; body weight; FDA; Food and Drug Administration; GLP; Good Laboratory Practice; MOE; margin of exposure; NCTR; Natio
Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits
Keywords: سازمان غذا و دارو (آمریکا); Opiates; Narcotic; Motility; BFI; bowel function index; FDA; Food and Drug Administration; IBS; irritable bowel syndrome; LES; lower esophageal sphincter; NBS; narcotic bowel syndrome; OIC; opioid-induced constipation; PAMORA; peripherally acting mu opioi
Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance
Keywords: سازمان غذا و دارو (آمریکا); FDA; US Food and Drug Administration; EGFR; epidermal growth factor receptor; BTK; Bruton's tyrosine kinase; SPR; surface plasmon resonance; PI3K; phosphoinositide 3-kinase; SD; standard deviation; SE; standard error; PI3K; phosphoinositide 3-kinase; SPR;
Changes in the expression level of MAPK pathway components induced by monosodium glutamate-administration produce neuronal death in the hippocampus from neonatal rats
Keywords: سازمان غذا و دارو (آمریکا); Bw; body weight; Eq; equivalent; eqNaCl; Equimolar NaCl Control Group; FDA; fluorescein diacetate; Glu; glutamate; MAPK; mitogen protein kinases; MSG; monosodium glutamate; PD; postnatal day; PI; propidium iodide; pRb; phosphorylates retinoblastoma protei
Effects of bisphenol A on incidence and severity of cardiac lesions in the NCTR-Sprague-Dawley rat: A CLARITY-BPA study
Keywords: سازمان غذا و دارو (آمریکا); BPA; bisphenol A; CEBS; chemical effects in biological systems; CLARITY BPA; consortium linking academic and regulatory insights on bpa toxicity; CMC; carboxymethylcellulose; CVD; cardiovascular disease; EE; 17α-ethinyl-estradiol; FDA; food and drug admi
Toxicological evaluation of the flavour ingredient N-(1-((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)-2-methylpropan-2-yl)-2,6-dimethylisonicotinamide (S2218)
Keywords: سازمان غذا و دارو (آمریکا); amu; atomic mass units; AUC; area under the curve; CBPI; cytokinesis-blocked proliferation index; CL; plasma clearance; Cmax; peak plasma concentration; CYP; cytochrome P450; EIC; extracted ion chromatogram; FDA; Food and Drug Administration; FEMA; Flavou
PD-L1 expression in advanced NSCLC: Insights into risk stratification and treatment selection from a systematic literature review
Keywords: سازمان غذا و دارو (آمریکا); ALK; anaplastic lymphoma kinase; CI; confidence interval; ECOG; The Eastern Cooperative Oncology Group; DCB; durable clinical benefit; DCR; disease control rate; EGFR; epidermal growth factor receptor; EGFRm+; EGFR mutation positive; FDA; Food and Drug Ad
Method of data interpretation for the determination of abuse liability in rodent self-administration studies under the FDA guidance document
Keywords: سازمان غذا و دارو (آمریکا); Self-administration; Drug control policy; Extinction; Reinforcement; Acute reinforcer; Acute tolerance; Methods; FDA; DEA; New drug application;
International therapeutic guidelines for patients with HCV-related extrahepatic disorders. A multidisciplinary expert statement
Keywords: سازمان غذا و دارو (آمریکا); HCV; hepatitis C virus; HCV-EHMs; HCV-extrahepatic manifestations; IFN; interferon; CV; cryoglobulinemic vasculitis; AVT; antiviral therapy; Peg-IFN; pegylated interferon; RBV; ribavirin; DAAs; direct-acting antiviral agents; FDA; food and drug administra
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors
Keywords: سازمان غذا و دارو (آمریکا); Heme Oxygenase; 2D-QSAR; pIC50 prediction; FDA; CORAL;
Paclitaxel: What has been done and the challenges remain ahead
Keywords: سازمان غذا و دارو (آمریکا); CN; chemotherapy naïve; CR; complete response; CrEL; Cremophor EL; DLT; dose limiting toxicities; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphocholine; DOTAP; 1,2-dioleoyl-3-Trimethylammonium Propane; DTIC; dacarbazine; ET; Endo-Tag1®; FDA; Food and Drug Admi
Developments of Polysorbate (Tween) based microemulsions: Preclinical drug delivery, toxicity and antimicrobial applications
Keywords: سازمان غذا و دارو (آمریکا); UV; ultra violet; FAO; Food and Agriculture Organization of the United Nations; WHO; World Health Organization; BCS; biopharmaceutics classification system; GRAS; generally recognized as safe; FDA; food and drug administration; TEM; transmission electron
Current therapy for chronic hepatitis C: The role of direct-acting antivirals
Keywords: سازمان غذا و دارو (آمریکا); Direct-acting antivirals; NS3/4A drugs; NS5A drugs; NS5B drugs; BID; twice a day; CDC; Centers for Disease Control and Prevention; DAA; direct-acting antiviral; EC50; half maximal effective concentration; FDA; U S Food and Drug Administration; GT; genotyp
PCSK9 inhibitors may improve cardiovascular outcomes-Can we afford them?
Keywords: سازمان غذا و دارو (آمریکا); CV; cardiovascular; FDA; Food and Drug Administration; HCV; hepatitis C virus; ICER; Institute for Clinical and Economic Review; LDL; low-density lipoprotein; MACE; major adverse cardiovascular events; MI; myocardial infarction; PCSK9i; proprotein convert