Synergistic antiviral activity of gemcitabine and ribavirin against enteroviruses
Keywords: جمسیتابین; Enteroviruses; Antiviral inhibitor; Gemcitabine; Ribavirin;
مقالات ISI جمسیتابین (ترجمه نشده)
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Gemcitabine and γ-cyclodextrin/docetaxel inclusion complex-loaded liposome for highly effective combinational therapy of osteosarcoma
Keywords: جمسیتابین; Osteosarcoma; Liposome; Docetaxel; Gemcitabine; Cyclodextrin
Cisplatin and gemcitabine in patients with advanced biliary tract cancer (ABC) and persistent jaundice despite optimal stenting: Effective intervention in patients with luminal disease
Keywords: جمسیتابین; Advanced biliary tract cancer; Chemotherapy; Jaundice; Bilirubin; Cisplatin; Gemcitabine;
A prospective randomised phase-II trial with gemcitabine versus gemcitabine plus sunitinib in advanced pancreatic cancer
Keywords: جمسیتابین; Pancreatic cancer; Gemcitabine; Sunitinib; Combination;
Multicentre randomised phase II trial of gemcitabine + platinum, with or without trastuzumab, in advanced or metastatic urothelial carcinoma overexpressing Her2
Keywords: جمسیتابین; Advanced urothelial carcinoma; Gemcitabine; Platinum salts; Trastuzumab; Her2 overexpression;
Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells
Keywords: جمسیتابین; Gem; gemictabine; PKM2; pyruvate kinase isoenzymes muscle type 2; CASP3/7; caspase 3 & 7; c. PARP; cleaved poly ADP ribose polymerase; BAX; BCL2-associated X protein; CDKN1A; cyclin-dependent kinase inhibitor 1A; BAK1; BCL2-antagonist; Bcl-xL; BCL2-like 1
Synergistic activity of combination therapy with PEGylated pemetrexed and gemcitabine for an effective cancer treatment
Keywords: جمسیتابین; Combination therapy; PEGylation; Pemetrexed; Gemcitabine; Bioavailability; Cytotoxicity;
Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells
Keywords: جمسیتابین; Phosphorylated HSP27; Nonphosphorylated HSP27; Gemcitabine; Pancreatic cancer; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; DR5; death receptor 5; EGFP; enhanced green fluorescence protein; XIAP; X-linked inhibitor of apoptosis; MAPK; m
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
Keywords: جمسیتابین; autophagy; onconase; pancreatic cancer; reactive oxygen species (ROS); mammalian target of rapamycin (mTOR); gemcitabine;
Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine
Keywords: جمسیتابین; Pancreatic adenocarcinoma; Gemcitabine; Mutant p53; Gain-of-function (GOF); Autophagy; p53-reactivating molecules
Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer
Keywords: جمسیتابین; CD44 targeting; Polymeric prodrug; Gemcitabine; Paclitaxel; Biliary cancer; Combined cancer therapy;
Diagnosis and Management of Urothelial Carcinoma In Situ of the Lower Urinary Tract: A Systematic Review
Keywords: جمسیتابین; Urothelial carcinoma in situ; Bacillus Calmette-Guérin; Intravesical immunotherapy; Valrubicin; Gemcitabine; Hyperthermia; Interferon-α; Bladder; Photodynamic diagnosis; Fluorescent cystoscopy; Narrow-band cystoscopy
Gemcitabine resistance in pancreatic ductal adenocarcinoma
Keywords: جمسیتابین; Gemcitabine; Chemoresistance; Metabolism; Environment mediated drug resistance; Pancreatic ductal adenocarcinoma
Tumor priming by Apo2L/TRAIL reduces interstitial fluid pressure and enhances efficacy of liposomal gemcitabine in a patient derived xenograft tumor model
Keywords: جمسیتابین; Apo2L/TRAIL; Patient tumor xenograft; Interstitial fluid pressure; Gemcitabine; Liposomes; Drug uptake;
In vitro immunomodulatory properties of gemcitabine alone and in combination with interferon-alpha
Keywords: جمسیتابین; 5FU; 5-fluorouracil; CTC; cytotoxic T cells; DC; dendritic cells; FACS; fluorescence activated cell sorting; Gem; gemcitabine; IFN; interferon-α; LAK; lymphokine-activated killer; MDSC; myeloid-derived suppressor cells; NK cells; nature killer cells; PDA
Molecular self-assembly of amphiphilic cyclic phosphoryl gemcitabine with different N-fatty acyl tails and enhanced anticancer effects of the self-assembled nanostructures
Keywords: جمسیتابین; Gemcitabine; Langmuir monolayers; Molecular self-assembly; Nanostructure; Phosphorylation; Simulation;
A whole genome RNAi screen identifies replication stress response genes
Keywords: جمسیتابین; Replication stress; ATR; Checkpoint; RNAi screen; DNA damage; Hydroxyurea; Gemcitabine; Camptothecin; PARP inhibitor;
Vinorelbine and gemcitabine as second- or third-line therapy for malignant pleural mesothelioma
Keywords: جمسیتابین; Mesothelioma; Vinorelbine; Gemcitabine; Chemotherapy
Rationale and Design of MILES-3 and MILES-4 Studies: Two Randomized Phase 3 Trials Comparing Single-Agent Chemotherapy Versus Cisplatin-Based Doublets in Elderly Patients With Advanced Non–Small-Cell Lung Cancer
Keywords: جمسیتابین; Advanced NSCLC; Cisplatin; Elderly; Gemcitabine; Pemetrexed; Randomized trial
Syntheses of 5â²-amino-2â²,5â²-dideoxy-2â²,2â²-difluorocytidine derivatives as novel anticancer nucleoside analogs
Keywords: جمسیتابین; Nucleoside; Gemcitabine; Reductive amination; Anticancer;
OncologySorafenib does not improve efficacy of chemotherapy in advanced pancreatic cancer: A GISCAD randomized phase II study
Keywords: جمسیتابین; Cisplatin; Gemcitabine; Pancreatic cancer; Phase II study; Sorafenib;
A phase II study of gemcitabine, carboplatin and bevacizumab for the treatment of platinum-sensitive recurrent ovarian cancer
Keywords: جمسیتابین; Ovarian cancer; Chemotherapy; Platinum-sensitive; Recurrent; Gemcitabine; Bevacizumab
Expression of Nucleoside Transporters and Deoxycytidine Kinase Proteins in Muscle Invasive Urothelial Carcinoma of the Bladder: Correlation with Pathological Response to Neoadjuvant Platinum/Gemcitabine Combination Chemotherapy
Keywords: جمسیتابین; neoadjuvant therapy; drug therapy; carcinoma; transitional cell; gemcitabine; nucleoside transport proteinsdCK, deoxycytidine kinase; MVAC, methotrexate, vinblastine, doxorubicin and cisplatin; NAC, neoadjuvant chemotherapy; NT, nucleoside transporter; RC
Phase II Randomized Study of Vandetanib Plus Gemcitabine or Gemcitabine Plus Placebo as First-Line Treatment of Advanced Non-Small-Cell Lung Cancer in Elderly Patients
Keywords: جمسیتابین; Vandetanib; Gemcitabine; Non-small-cell lung cancer; Elderly;
Multi-institutional analysis of sequential intravesical gemcitabine and mitomycin C chemotherapy for non-muscle invasive bladder cancer
Keywords: جمسیتابین; Bladder cancer; Gemcitabine; Mitomycin; Antineoplastic therapy; Chemotherapy protocols;
In situ evaluation of gemcitabine–DNA interaction using a DNA-electrochemical biosensor
Keywords: جمسیتابین; Gemcitabine; DNA; Guanine; Electrochemical DNA-biosensor; Interaction mechanism
Randomized, Double-Blind, Phase II Trial Comparing Gemcitabine-Cisplatin plus the LTB4 Antagonist LY293111 versus Gemcitabine-Cisplatin plus Placebo in First-Line Non–Small-Cell Lung Cancer
Keywords: جمسیتابین; Cisplatin; Gemcitabine; hemotherapy; Leukotriene receptor agonist; Lung cancer; LY293111; Peroxisome proliferators; Activated receptor γ agonist
Facile method for determination of deoxycytidine kinase activity in biological milieus
Keywords: جمسیتابین; Chemiluminescent assay; Deoxycytidine kinase; Gemcitabine
Cytotoxic activity of gemcitabine, alone or in combination with mitotane, in adrenocortical carcinoma cell lines
Keywords: جمسیتابین; Adrenocortical cancer; Gemcitabine; Mitotane; Cell lines;
Phase II trial of first-line chemotherapy with gemcitabine, etoposide, and cisplatin for patients with advanced urothelial carcinoma
Keywords: جمسیتابین; Advanced urothelial carcinoma; Gemcitabine; Etoposide; Cisplatin; Phase II study; First-line chemotherapy;
Gemcitabine-treated pancreatic cancer cell medium induces the specific CTL antitumor activity by stimulating the maturation of dendritic cells
Keywords: جمسیتابین; Pancreatic cancer; Chemotherapy; Immunotherapy; Gemcitabine; Dendritic cell
MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX
Keywords: جمسیتابین; BMP; bone morphogenetic protein; EMT; epithelial-mesenchymal transition; HSP; heat shock protein; ID; Inhibitor of DNA binding; IPMN; intraductal papillary mucinous neoplasm; MTT; 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide; SHC1; Src
Effect of gemcitabine and retinoic acid loaded PAMAM dendrimer-coated magnetic nanoparticles on pancreatic cancer and stellate cell lines
Keywords: جمسیتابین; Gemcitabine; Retinoic acid; PAMAM dendrimer; Nanoparticle; Pancreatic cancer; Stellate cell lines
Efficacy and safety of pemetrexed/cisplatin versus gemcitabine/cisplatin as first-line treatment in Chinese patients with advanced nonsquamous non-small cell lung cancer
Keywords: جمسیتابین; Cisplatin; Chinese; First-line chemotherapy; Gemcitabine; Non-small cell lung cancer; Nonsquamous; Pemetrexed;
Involvement of p38 mitogen-activated protein kinase in acquired gemcitabine-resistant human urothelial carcinoma sublines
Keywords: جمسیتابین; Drug resistance; Gemcitabine; p38 mitogen-activated protein kinase; Urothelial carcinoma
Development of a gradient high performance liquid chromatography assay for simultaneous analysis of hydrophilic gemcitabine and lipophilic curcumin using a central composite design and its application in liposome development
Keywords: جمسیتابین; Gemcitabine; Curcumin; Central composite design; Desirability function; Gradient high performance liquid chromatography validation
The identification of novel 5â²-amino gemcitabine analogs as potent RRM1 inhibitors
Keywords: جمسیتابین; Ribonucleotide reductase; Gemcitabine; CHK1; Deoxyribonucleotides; Oncology;
N-Acyl-phosphoramidates as potential novel form of gemcitabine prodrugs
Keywords: جمسیتابین; Gemcitabine; Prodrug; Cytotoxicity; Anticancer therapy; DNA polymerase inhibitor;
Genetic polymorphisms of SLC28A3, SLC29A1 and RRM1 predict clinical outcome in patients with metastatic breast cancer receiving gemcitabine plus paclitaxel chemotherapy
Keywords: جمسیتابین; Paclitaxel; Gemcitabine; Pharmacogenomics; Breast cancer;
Gemcitabine plus cisplatin versus chemoradiotherapy in locally advanced biliary tract cancer: Fédération Francophone de Cancérologie Digestive 9902 phase II randomised study
Keywords: جمسیتابین; Chemoradiotherapy; Fluorouracil; Cisplatin; Gemcitabine; Oxaliplatin; Biliary tract cancer;
Gemcitabine-induced myopathy
Keywords: جمسیتابین; Myopathy; Vasculopathy; Gemcitabine
Polychemotherapy or gemcitabine in advanced pancreatic cancer: A meta-analysis
Keywords: جمسیتابین; First line; Gemcitabine; Meta-analysis; Overall survival; Pancreatic cancer; Polychemotherapy
Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs
Keywords: جمسیتابین; Pancreatic cancer; Autophagy; Chemotherapy; PANC-1; BxPC-3; 5-Fluorouracil; Gemcitabine; Chloroquine; Wortmannin; LC3
Single domain antibody against carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) inhibits proliferation, migration, invasion and angiogenesis of pancreatic cancer cells
Keywords: جمسیتابین; MMP-2; Matrix metalloproteinase-2; MMP-9; Matrix metalloproteinase-9; Fc; fragment crystallizable; IC50s; Half maximal inhibitory concentration; DMEM; Dulbecco's Modified Eagle Medium; PET; Positron emission tomography; FACS; Fluorescence-activated cell
Human equilibrative nucleoside transporter 1 is not predictive for gemcitabine efficacy in advanced pancreatic cancer: Translational results from the AIO-PK0104 phase III study with the clone SP120 rabbit antibody
Keywords: جمسیتابین; Gemcitabine; hENT1; Pancreatic cancer
Gemcitabine-induced pancreatic cancer cell death is associated with MST1/Cyclophilin D mitochondrial complexation
Keywords: جمسیتابین; Gemcitabine; Pancreatic cancer; MST1; Cyclophilin D; Cell deathCyp-D, Cyclophilin D; CsA, cyclosporin A; H2O2, hydrogen Peroxide; MST1, mammalian sterile 20-like kinase 1; ROS, reactive oxygen species; NAC, n-acetyl-cysteine
Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases
Keywords: جمسیتابین; Glaucarubinone; Gemcitabine; Pancreatic cancer; P21-activated kinases;
N-acetyl-l-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway
Keywords: جمسیتابین; Gemcitabine; Glutathione; N-acetyl-l-cysteine; Pancreatic cancer; S-glutathionylation
Combination cytotoxicity of backbone degradable HPMA copolymer gemcitabine and platinum conjugates toward human ovarian carcinoma cells
Keywords: جمسیتابین; HPMA copolymers; Biodegradable polymers; Combination therapy; Ovarian cancer; Gemcitabine; DACH Pt
Comparison of Gemcitabine Combined With Targeted Agent Therapy Versus Gemcitabine Monotherapy in the Management of Advanced Pancreatic Cancer
Keywords: جمسیتابین; combination therapy; gemcitabine; pancreatic cancer; survival benefit; targeted agent