The flavonoid apigenin inhibits hepatitis C virus replication by decreasing mature microRNA122 levels
Keywords: هپاتیت سی; HCV; MicroRNA; Replicon; Polyphenol;
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Research ArticleFracture risk in hepatitis C virus infected persons: Results from the DANVIR cohort study
Keywords: هپاتیت سی; HCV; hepatitis C virus; CI; confidence interval; aIRR; adjusted incidence rate ratio; BMD; bone mineral density; CRS; Civil Registration System; DNPR; Danish National Hospital Registry; ICD-8; International Classification of Diseases, revision 8; ICD-10;
Research ArticleProspective evaluation of FibroTest®, FibroMeter®, and HepaScore® for staging liver fibrosis in chronic hepatitis B: Comparison with hepatitis C
Keywords: هپاتیت سی; CHC; chronic hepatitis C; CHB; chronic hepatitis B; TE; Transient elastography; FT; FibroTest; AUROC; Area under the receiver operator characteristic; FM; FibroMeter; HS; HepaScore; HBV; Hepatitis B virus; HCV; Hepatitis C virus; PPV; Positive predictive
Research ArticleA US multicenter study of hepatitis C treatment of liver transplant recipients with protease-inhibitor triple therapy
Keywords: هپاتیت سی; HCV; hepatitis C virus; SVR; sustained virological response; PI; protease inhibitor; CRUSH-C; The Consortium to Study Health Outcomes in HCV Liver Recipients; HCV RNA; hepatitis C virus ribonucleic acid; eRVR; extended rapid virological response; EOTR; en
Journal of Hepatology Update: Hepatitis CAntiviral therapy with nucleotide polymerase inhibitors for chronic hepatitis C
Keywords: هپاتیت سی; HCV; hepatitis C virus; PegIFN; pegylated interferon; RBV; ribavirin; SVR; sustained virologic response; DAAs; direct-acting antiviral agents; SOF; sofosbuvir; SIM; simeprevir; FDA; United States Food and Drug Administration; EMA; European Medicines Agenc
Journal of Hepatology Update: Hepatitis CSimplification of antiviral hepatitis C virus therapy to support expanded access in resource-limited settings
Keywords: هپاتیت سی; ARV; antiretroviral; ART; antiretroviral therapy; DAA; direct-acting antiviral agent; FDC; fixed-dose combination; HCV; hepatitis C virus; HIV; human immunodeficiency virus; IFN; interferon; PCR; polymerase chain reaction; RBV; ribavirin; WHO; World Healt
Research ArticleA common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease
Keywords: هپاتیت سی; AFP; alpha fetoprotein; NCAN; neurocan; NAFLD; non-alcoholic fatty liver disease; ALD; alcoholic liver disease; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; OR; odds ratio; CI; confidence interval; ECM; extracellular matrix; SNP; single nucleoti
Research ArticleExtended duration therapy with pegylated interferon and ribavirin for patients with genotype 3 hepatitis C and advanced fibrosis: Final results from the STEPS trial
Keywords: هپاتیت سی; AE; adverse event; Hb; hemoglobin; HCV; hepatitis C virus; HIV; human immunodeficiency virus; PegIFN/RBV; peginterferon-α and ribavirin; RNA; ribonucleic acid; RVR; rapid virologic response; SAE; serious adverse event; SVR; sustained virologic response;
Research ArticleHigh hepatitis B virus surface antigen levels and favorable interleukin 28B genotype predict spontaneous hepatitis C virus clearance in uremic patients
Keywords: هپاتیت سی; ALT; alanine aminotransferase; AST; aspartate aminotransferase; HBV; hepatitis B virus; HCV; hepatitis C virus; HBsAg; hepatitis B surface antigen; ESRD; end-stage renal disease; IL-28B; interleukin 28B; SNP; single nucleotide polymorphism; IL-28B; HCV; H
Research ArticleLiver fibrosis progression at autopsy in injecting drug users infected by hepatitis C: A longitudinal long-term cohort study
Keywords: هپاتیت سی; HCV; hepatitis C virus; IDU; injecting drug user; RNA; ribonucleic acid; anti-HCV; hepatitis C antibody; CHC; chronic hepatitis C; HBsAg; hepatitis B surface antigen; anti-HBc; hepatitis B core antibody; HCC; hepatocellular carcinoma; CI; confidence inter
Research ArticleLong-term follow-up of hepatitis C infection in a large cohort of patients with inherited bleeding disorders
Keywords: هپاتیت سی; HCV; hepatitis C virus; ESLD; end-stage liver disease; IFN; interferon; PegIFN; pegylated interferon; LSM; liver stiffness measurement; UK; United Kingdom; HCC; hepatocellular carcinoma; SVR; sustained virological response; CI; confidence interval; HR; ha
Research ArticleKIR2DL3+NKG2Aâ natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs
Keywords: هپاتیت سی; APC; Allophycocyanin; APC-Cy7; Allophycocyanin-Cyanine7; PBMC; Peripheral blood mononuclear cell; PE; Phycoerythrin; CD; Cluster of differentiation; FITC; Fluorescein isothiocyanate; HBV; hepatitis B virus; HCV; hepatitis C virus; HLA; Human Leukocyte Ant
Risky behavior and correlates of HIV and Hepatitis C Virus infection among people who inject drugs in three cities in Afghanistan
Keywords: هپاتیت سی; HIV; HCV; HBV; HSV; PWID; Afghanistan;
Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro
Keywords: هپاتیت سی; Solanum rantonnetii; Aerial parts; Flavonoids; Antiviral activity; HCV;
Comparative Effectiveness of Telaprevir-Based Triple Therapy in Patients With Chronic Hepatitis C
Keywords: هپاتیت سی; HCV; hepatitis C virus; p-IFN; pegylated interferon; RBV; ribavirin; RVR; rapid virologic response; SVR; sustained virologic response;
Transitions from injecting to non-injecting drug use: Potential protection against HCV infection
Keywords: هپاتیت سی; HIV; HCV; Drug use; Substance abuse; Non-injecting drug use; Injecting drug use;
Discovery of functionalized bisimidazoles bearing cyclic aliphatic-phenyl motifs as HCV NS5A inhibitors
Keywords: هپاتیت سی; HCV; NS5A inhibitor; Bisimidazole;
Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors
Keywords: هپاتیت سی; HCV; NS5B polymerase; PXR; CYP induction; Lactam; Thiophene;
Cysteine-rich secretory protein 3 inhibits hepatitis C virus at the initial phase of infection
Keywords: هپاتیت سی; HCV; hepatitis C virus; CA9; carbonic anhydrase 9; CRISP3; cysteine-rich secretory protein 3; CSTA; cystatin-A; IFITM2; interferon-induced transmembrane protein 2; KLF2; Krueppel-like factor 2; FIHC; fluorescent immunohistochemistry; MRI; magnetic resonan
Resistance to cyclosporin A derives from mutations in hepatitis C virus nonstructural proteins
Keywords: هپاتیت سی; HCV; hepatitis C virus; CsA; cyclosporine A; HCC; hepatocellular carcinoma; IFNα; alpha interferon; Cyp; cyclophilins; SVR; sustained anti-viral response; Hepatitis C virus; Cyclosporine A; Cyclophylin inhibitor; Mutation; Debio-025;
Inhibition of herpes simplex virus type 1 entry by chloride channel inhibitors tamoxifen and NPPB
Keywords: هپاتیت سی; ACV; acyclovir; CtxB; choleratoxin beta subunit; ER; estrogen receptor; FDA; food and drug administration; HCV; hepatitis C virus; HSV; herpes simplex virus; MQAE; N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide; NPPB; 5-nitro-2-(3-pheny l-propylami
Research ArticlePrevalence and causes of elevated serum aminotransferase levels in a population-based cohort of persons with chronic hepatitis B virus infection
Keywords: هپاتیت سی; HBV; hepatitis B virus; DNA; deoxyribonucleic acid; NAFLD; non-alcoholic fatty liver disease; ALT; alanine aminotransferase; AST; aspartate aminotransferase; HCV; hepatitis C virus; HDV; hepatitis D virus; NHANES; National Health and Nutrition Examination
Research ArticleApolipoprotein H expression is associated with IL28B genotype and viral clearance in hepatitis C virus infection
Keywords: هپاتیت سی; HCV; Hepatitis C virus; VLDL; very low density lipoprotein; Apo; apolipoprotein; aHCV; acute hepatitis C; cHCV; chronic hepatitis C; LVP; lipoviral particle; ALT; serum alanine aminotransferase; RNA; ribonucleic acid; PCR; polymerase chain reaction; MAP;
Neutralizing antibodies and broad, functional T cell immune response following immunization with hepatitis C virus proteins-based vaccine formulation
Keywords: هپاتیت سی; HCV; Neutralizing antibody; T cell proliferation; Mice; Monkeys; IFN-γ
Pore-forming activity of pestivirus p7 in a minimal model system supports genus-specific viroporin function
Keywords: هپاتیت سی; BVDV; bovine viral diarrhea virus; CD; circular dichroism; Chol; cholesterol; CL; cardiolipin; CSFV; classical swine fever virus; HCV; hepatitis C virus; PC; phosphatidylcholine; PE; phospahtidylethanolamine; PS; phosphatidylserine; PI; phosphatidylinosit
Sex-specific association of estrogen receptor 2 polymorphisms with hepatitis C virus infection outcomes in a high-risk Chinese Han population
Keywords: هپاتیت سی; HCV; hepatitis C virus; HD; hemodialysis; NF; nuclear factor; IL; interleukin; ER; estrogen receptor; ESR1; estrogen receptor 1; SNPs; single nucleotide polymorphisms; 3â²-UTR; 3â²-untranslated region; RA; rheumatoid arthritis; ELISA; enzyme-linked immu
Association Between a Polymorphism in Cannabinoid Receptor 2 and Severe Necroinflammation in Patients With Chronic Hepatitis C
Keywords: هپاتیت سی; Cannabinoid System; SNP; Genetics; Disease Progression; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CB; cannabinoid receptor; CHC; chronic hepatitis C; CNR; cannabinoid receptor 2; HAI; Histologic Activity Index; HCV; hepatitis C virus
Back to the origin of HCV 2c subtype and spreading to the Calabria region (Southern Italy) over the last two centuries: A phylogenetic study
Keywords: هپاتیت سی; HCV; Phylogeny; Phylodynamics;
Review ArticleOverall efficacy and safety results of sofosbuvir-based therapies in Phase II and III studies
Keywords: هپاتیت سی; DAAs; HCV;
Toll-like receptor 7 variations are associated with the susceptibility to HCV infection among Chinese females
Keywords: هپاتیت سی; HCV; hepatitis C virus; TLR7; Toll-like receptor 7; SNP; single nucleotide polymorphism; HCC; hepatocellular carcinoma; PRR; pattern recognition receptor; PAMP; pathogen associated molecular pattern; ssRNA; single strand RNA; HIV; human immunodeficiency v
The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production
Keywords: هپاتیت سی; SMYD3; NS5A; HCV; TAP-MS; Virus particle assembly;
Optimization of peptide arrays for studying antibodies to hepatitis C virus continuous epitopes
Keywords: هپاتیت سی; HCV; E1E2 glycoprotein; Peptide array
The stability of secreted, acid-labile H77/JFH-1 hepatitis C virus (HCV) particles is altered by patient isolate genotype 1a p7 sequences
Keywords: هپاتیت سی; HCV; hepatitis C virus; DAA; direct-acting antivirals; NS; non-structural; HCC; nuclear hepatocellular carcinoma; IAV; influenza A virus; M2; matrix protein 2; vATPase; vacuolar adenosine tri-phosphatase; TM; trans-membrane; MeOH; methanol; rp-HPLC; rever
Efficient generation of highly immunocompetent dendritic cells from peripheral blood of patients with hepatitis C virus-related hepatocellular carcinoma
Keywords: هپاتیت سی; DC; dendritic cell; HCV; hepatitis C virus; IFN; interferon; PBMC; peripheral blood mononuclear cell; Immunotherapy; HCV; Cancer; Cytokine;
Peripheral blood mononuclear cells microRNA predicts treatment outcome of hepatitis C virus genotype 1 infection
Keywords: هپاتیت سی; HCV; PBMC; MicroRNA; SVR; IL28B; miR-125b;
Randomized clinical trial comparing high versus standard dose of ribavirin plus peginterferon alfa-2a in hepatitis C genotype 3 and high viral load. Dargen-3 study
Keywords: هپاتیت سی; Chronic hepatitis C; HCV; Genotype 3; Ribavirin; Sustained virological response; Rapid virological responseHepatitis crónica C; VHC; VHC genotipo 3; Ribavirina; Respuesta virológica sostenida; Respuesta virológica rápida
Can transient elastography, Fib-4, Forns Index, and Lok Score predict esophageal varices in HCV-related cirrhotic patients?
Keywords: هپاتیت سی; Esophageal varices; HCV; Liver stiffness measurement; Noninvasive predictors; Serum fibrosis scores; Varices esofágicas; VHC; Medida de la rigidez hepática; Predictores no invasivos; Valores séricos de fibrosis;
Many Patients With Interleukin 28B Genotypes Associated With Response to Therapy Are Ineligible for Treatment Because of Comorbidities
Keywords: هپاتیت سی; Interferon Lambda 3; Genetics; Liver Disease; SNP; DAA; direct acting antiviral; HCV; hepatitis C virus; SNP; single-nucleotide polymorphism; SVR; sustained virologic response;
Research ArticleShould we await IFN-free regimens to treat HCV genotype 1 treatment-naive patients? A cost-effectiveness analysis (ANRS 95141)
Keywords: هپاتیت سی; Boceprevir; Chronic hepatitis C; Cost-effectiveness analysis; Direct-acting antivirals; Genotype 1; Interferon-free regimens; Model-based analysis; Telaprevir; Treatment initiation; G1; genotype 1; HCV; hepatitis C virus; TVR; telaprevir; BOC; boceprevir;
MiR-221 accentuates IFN׳s anti-HCV effect by downregulating SOCS1 and SOCS3
Keywords: هپاتیت سی; HCV; Mir-221; SOCS1; SOCS3; IFN-α;
Research ArticleHLA-Bâ27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope
Keywords: هپاتیت سی; HLA; human leukocyte antigen; HCV; hepatitis C virus; NS5B; non-structural protein 5B; PBMC; peripheral blood mononuclear cell; EBV; Epstein Barr virus; B-LCL; B-lymphoblastoid cell lines; IFN-γ; interferon-gamma; Hepatitis C virus; CD8+ T cell response;
Recent developments in the search for a cure for HIV-1 infection: Targeting the latent reservoir for HIV-1
Keywords: هپاتیت سی; HIV; latency; eradication; reservoir; cure; stem cell transplantation; antiretroviral therapy; AML; Acute myelogenous leukemia; ART; Combination antiretroviral therapy; HCV; Hepatitis C virus; HSCT; Hematopoietic stem cell transplantation; LRA; Latency-re
Research ArticleExpression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis
Keywords: هپاتیت سی; HCV; hepatitis C virus; TGF-β; transforming growth factor β; IL; interleukin; ILT; Immunoglobulin-like transcript receptors; HIV; human immunodeficiency virus; HCMV; human cytomegalovirus; HBV; hepatitis B virus; IFN; interferon; OSM; oncostatin; MC; ma
Body Mass Index and Liver Stiffness Affect Accuracy of Ultrasonography in Detecting Steatosis in Patients With Chronic Hepatitis C Virus Genotype 1 Infection
Keywords: هپاتیت سی; BLEP; Fibrosis; Evaluation; Cirrhosis; ALT; alanine aminotransferase; BMI; body mass index; CHC; chronic hepatitis C; CI; confidence interval; G1; genotype 1; HCV; hepatitis C virus; HOMA; homeostasis model assessment; LR; likelihood ratio; LSM; liver sti
A New Laboratory-Based Algorithm to Predict Development of Hepatocellular Carcinoma in Patients With Hepatitis C and Cirrhosis
Keywords: هپاتیت سی; Prognosis; Liver Cancer; Prediction; Risk Factors; AFP; α-fetoprotein; ALT; alanine aminotransferase; AST; aspartate aminotransferase; EMR; electronic medical records; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; VA; Department of Veterans Affa
Research ArticleRandomized trial of asunaprevir plus peginterferon alfa and ribavirin for previously untreated genotype 1 or 4 chronic hepatitis C
Keywords: هپاتیت سی; HCV; hepatitis C virus; PegIFNα; peginterferon alfa; RBV; ribavirin; DAA; direct-acting antiviral; BID; twice daily; SVR24; sustained virologic response 24 weeks posttreatment; PDR; protocol-defined response; LLOQ; lower limit of quantification; EVR; ea
Research ArticleIncreased uptake and new therapies are needed to avert rising hepatitis C-related end stage liver disease in England: Modelling the predicted impact of treatment under different scenarios
Keywords: هپاتیت سی; HCV; hepatitis C; NHS; National Health Service; NICE; National Institute for Health and Care Excellence (formally National Institute for Health and Clinical Excellence); HPAI; Hospital Pharmacy Audit Index; ESLD; end-stage liver disease; HCC; hepatocellul
Research ArticleProtection against hepatitis C infection via NK cells in highly-exposed uninfected injecting drug users
Keywords: هپاتیت سی; HCV; hepatitis C virus; IDUs; injecting drug users; IN; incident; EU; exposed uninfected; NK; natural killer; ELISpot; enzyme linked immunosorbent assay; CTL; cytotoxic T lymphocyte; SNP; single nucleotide polymorphism; KIR; killer-like immunoglobulin rec
Development and validation of a useful UPLC–MS/MS method for quantification of total and phosphorylated-ribavirin in peripheral blood mononuclear cells of HCV+ patients
Keywords: هپاتیت سی; PBMC; HCV; Intracellular; Ribavirin; Phosphorylated drugs
Research ArticleBaseline gamma-glutamyl transferase levels strongly correlate with hepatocellular carcinoma development in non-cirrhotic patients with successful hepatitis C virus eradication
Keywords: هپاتیت سی; ALT; alanine aminotransferase; AST; aspartate aminotransferase; APRI; the aspartate aminotransferase-to-platelet ratio index; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IL-28B; interleukin 28B; γGT; gamma-glutamyl transferase; SVR; sustained