Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors
Keywords: هپاتیت سی; Amide bioisostere; HCV; Thumb; PDB; Hydrazine;
مقالات ISI هپاتیت سی (ترجمه نشده)
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3-Heterocyclyl quinolone inhibitors of the HCV NS5B polymerase
Keywords: هپاتیت سی; HCV; NS5B polymerase inhibitors; 3-Heterocyclyl quinolone analogs; NNI-2 binders;
Translocase of outer mitochondrial membrane 70 induces interferon response and is impaired by hepatitis C virus NS3
Keywords: هپاتیت سی; HCV; Tom70; MAVS; IFN; IRF-3; NS3;
Role of hepatic HCV-RNA level on the severity of chronic hepatitis C and response to antiviral therapy
Keywords: هپاتیت سی; HCV; hepatitic C virus; SVR; sustained virologic response; ALT; alanine aminotransferase; Pegylated interferon; Ribavirin; Hepatic HCV-RNA; Severity of liver disease;
The association between hepatitis C virus infection, genetic polymorphisms of oxidative stress genes and B-cell non-Hodgkin's lymphoma risk in Egypt
Keywords: هپاتیت سی; HCV; Oxidative stress genes; Genetic polymorphism; Antioxidant enzymes; B-NHL; NHL risk;
Discovery of GS-9451: An acid inhibitor of the hepatitis C virus NS3/4A protease
Keywords: هپاتیت سی; HCV; GS-9451; NS3 Protease; Solubilizing group
Non-fatal cardiovascular disease, malignancies, and other co-morbidity in adult haemophilia patients
Keywords: هپاتیت سی; AIDS; acquired immune deficiency syndrome; AP; angina pectoris; BMI; body mass index; CI; confidence interval; CVD; cardiovascular disease; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; HIV; human immunodeficiency virus; IQR; interquartile range;
Research ArticleIL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C
Keywords: هپاتیت سی; GWAS; genome wide association study; HCV; hepatitis C virus; IFN-λ3; interferon λ3; IL28B; interleukin 28B; NR; non response; PCR; polymerase chain reaction; PEG-IFN; pegylated interferon; RVR; rapid virological response; SNP; single nucleotide polymorp
Research ArticleRecurrence of hepatocellular cancer after liver transplantation: The role of primary resection and salvage transplantation in East and West
Keywords: هپاتیت سی; Liver transplantation; Hepatocellular cancer; Tumor recurrence; Living donation; Salvage transplantation; HBV; HCV; HCC; hepatocellular cancer; LT; liver transplantation; MC; Milan criteria; LDLT; living-donor liver transplantation; LR; liver resection; M
Research ArticleHuman pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus
Keywords: هپاتیت سی; AFP; α-foetoprotein; ALB; albumin; ApoB100; apolipoprotein B100; CLDN1; claudin-1; CLDN6; claudin-6; CYP3A4/5; cytochrome P450 family 3 subfamily A polypeptide 4/5; HCV; hepatitis C virus; hESC; human embryonic stem cells; HNF4α; hepatocyte nuclear fact
Research ArticleGaps in the achievement of effectiveness of HCV treatment in national VA practice
Keywords: هپاتیت سی; HCV; hepatitis C virus; SVR; sustained viral response; RCTs; randomized controlled trials; VA; Veterans Administration; CCR; Clinical Case Registry; PEG-INF; pegylated-interferon; COPD; chronic obstructive pulmonary disease; Hepatitis C virus; Antiviral t
Research Article13C-Aminopyrine breath test accurately predicts long-term outcome of chronic hepatitis C
Keywords: هپاتیت سی; Fibrosis progression; 13C-ABT; HCV-related chronic disease outcome; HCV; hepatitis C virus; AST; aspartate aminotransferase; ALT; alanine aminotrasferase; APRI; AST to platelet ratio index; 13C-ABT; 13C-aminopyrine breath test; GGT; gamma glutamyl transfe
Research ArticleShort course adjuvant terlipressin in acute variceal bleeding: A randomized double blind dummy controlled trial
Keywords: هپاتیت سی; EVBL; esophageal variceal band ligation; EVB; esophageal variceal bleed; SC; short course; UC; usual course; HCV; hepatitis C Virus; PVT; portal vein thrombosis; HCC; hepatocellular carcinoma; GCP; good clinical practice; ER; emergency room; GV; gastric v
Optimization and application of subtype specific polymerase chain reaction for detection and identification of mixed subtypes of hepatitis C virus in patients with renal disease
Keywords: هپاتیت سی; HCV; Mixed genotypes; Patterns; Reverse transcriptase PCR; Real time PCR;
β-d-2â²-α-F-2â²-β-C-Methyl-6-O-substituted 3â²,5â²-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: A structure-activity relationship study
Keywords: هپاتیت سی; PSI-352938; PSI-353661; HCV; Nucleoside; Nucleotide; Antiviral; Prodrug; NS5B; Cyclic phosphate; Hepatitis C virus;
Synthesis and characterization of 2â²-C-Me branched C-nucleosides as HCV polymerase inhibitors
Keywords: هپاتیت سی; C-Nucleoside; Antiviral; HCV; Polymerase inhibitor;
Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein
Keywords: هپاتیت سی; AA3; aminoacylase 3; ER; endoplasmatic reticulum; HCV; hepatitis C virus; hepatitis C virus core protein; HCVCP; MS; mass-spectrometry; NBCe1-A; the kidney specific form of the electrogenic sodium bicarbonate cotransporter 1; Aminoacylase 3; Hepatitis C v
A new class of pyrimidine nucleosides: inhibitors of hepatitis B and C viruses
Keywords: هپاتیت سی; HBV, hepatitis B virus; HBsAg, hepatitis B surface antigen; 3-TC, β-l-(−)-2′,3′-dideoxy-3′-thiacytidine; DHBV, duck hepatitis B virus; cccDNA, covalently closed circular DNA; EC50, 50% effective concentration; CC50, 50% cytotoxic concentrationHBV; HCV; An
Perfil serológico en gestantes extranjeras frente a VIH, VHB, VHC, virus de la rubéola, Toxoplasma gondii, Treponema pallidum, y Trypanosoma cruzi
Keywords: هپاتیت سی; Serología; Embarazada; VIH; VHB; VHC; Treponema pallidum; Toxoplasma gondii; Trypanosoma cruzi; Rubéola; InmigranteSerology; Pregnant women; HIV; HBV; HCV; Treponema pallidum; Toxoplasma gondii; Trypanosoma cruzi; Rubeola; Immigrant
Analysis of variables and interactions among variables associated with a sustained virological response to pegylated interferon alfa-2a plus ribavirin in hepatitis C virus genotype 3-infected patients
Keywords: هپاتیت سی; HCV; Pegylated interferon; HCV genotype 3
Determinants of Serum Alpha-Fetoprotein Levels in Hepatitis C-Infected Patients
Keywords: هپاتیت سی; Biomarker; Risk; Liver Cancer; Disease Progression; AFP; alpha fetoprotein; ALT; alanine aminotransferase; AST; aspartate aminotransferase; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; ICD-9-CM; International Classification of Diseases-ninth rev
Tegobuvir (GS-9190) potency against HCV chimeric replicons derived from consensus NS5B sequences from genotypes 2b, 3a, 4a, 5a, and 6a
Keywords: هپاتیت سی; HCV; NS5B; GS-9190; Tegobuvir; Chimeric; Replicon
Correlation between alanine aminotransferase level, HCV-RNA titer and fibrosis stage in chronic HCV genotype 4 infection
Keywords: هپاتیت سی; HCV; RNA; ALT; Fibrosis; Genotype 4; Chronic hepatitis
Pilot study for assessment of prevalence of intrafamilial hepatitis C transmission in relation to salivary viral load among infected patients with and without chronic renal failure
Keywords: هپاتیت سی; Salivary; HCV; HCV PCR; Intrafamilial transmission
Development of a novel score for liver fibrosis staging and comparison with eight simple laboratory scores in large numbers of HCV-monoinfected patients
Keywords: هپاتیت سی; HCV; Liver fibrosis; Blood markers; Score
Antiviral therapy and fibrosis progression in patients with mild–moderate hepatitis C recurrence after liver transplantation. A randomized controlled study
Keywords: هپاتیت سی; HCV; PEG-Interferon; Recurrent hepatitis; Ribavirin
Primary care-based interventions are associated with increases in hepatitis C virus testing for patients at risk
Keywords: هپاتیت سی; Chronic hepatitis C; HCV; Primary care; Public health; Screening
Vitamin D3 modulates T lymphocyte responses in hepatitis C virus-infected liver transplant recipients
Keywords: هپاتیت سی; HCV; Immunosuppression; Liver transplant; T lymphocytes; Vitamin D3
Levels of Alanine Aminotransferase Confound Use of Transient Elastography to Diagnose Fibrosis in Patients With Chronic Hepatitis C Virus Infection
Keywords: هپاتیت سی; Fibroscan; Diagnostic Test; Imaging; Chronic HCV; ALT; alanine aminotransferase; BMI; body mass index; CI; confidence interval; HCV; hepatitis C virus; HE; hepatic elastography; HIV; human immunodeficiency virus; kPa; kilopascals; LSM; liver stiffness mea
Role of glypican-3 in the early diagnosis of hepatocellular carcinoma among Egyptian patients
Keywords: هپاتیت سی; HCC; GPC3; AFP; HCV; Serum marker
Hemochromatosis Gene Mutations: Prevalence and Effects on Pegylated-Interferon and Ribavirin Therapy Response in Chronic Hepatitis C in Sardinia
Keywords: هپاتیت سی; HFE gene; iron overload; viral hepatitis; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AP; alkaline phosphatase; CHC; Chronic hepatitis C; ETR; End of treatment response; GGT; g-glutamyl transpeptidase; HFE; Human hemochromatosis protei
Research ArticleRaloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal women with chronic hepatitis C: A randomized trial
Keywords: هپاتیت سی; HCV; hepatitis C virus; SVR; sustained virological response; SOC; standard of care; PegIFN; pegylated interferon; RBV; ribavirin; RLX; raloxifene hydrochloride; IL28B; interleukin-28B; SERM; selective estrogen receptor modulator; WBC; white blood cell; Hb
Research ArticleInsulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1
Keywords: هپاتیت سی; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PegIFN; pegylated interferon; RBV; ribavirin; SVR; sustained virological response; SNPs; single nucleotide polymorphisms; IL28B; interleukin 28B; BMI; body mass index; HOMA-IR; Homeostasis Model Asses
Research ArticleAssociation of the IL28B genotype with insulin resistance in patients with chronic hepatitis C
Keywords: هپاتیت سی; CHC; chronic hepatitis C; HCV; hepatitis C virus; HOMA; homeostasis model of assessment; IR; insulin resistance; IL28B; interleukin 28 B; PNPLA3; patatin like phospholipase domain-containing 3; SVR; sustained virologic response; SNP; single nucleotide pol
Research ArticleThe metabolic regulator PGC-1α links hepatitis C virus infection to hepatic insulin resistance
Keywords: هپاتیت سی; HCV; hepatitis C virus; PGC-1α; peroxisome proliferator-activated receptor gamma, co-activator 1α; G6Pase; glucose-6 phosphatase; RNA; ribonucleic acid; PI3; phosphatidylinositol 3-kinase; FLRP; full length replicon; SGR; subgenomic replicon; NS5A; non-
Research ArticleA population-based study of the epidemiology of hepatitis C in a North American population
Keywords: هپاتیت سی; HCV; hepatitis C virus; VHSD; Viral Hepatitis Surveillance Database; CDC; Communicable Disease Control; anti-HCV; antibody to hepatitis C virus; PHIN; Personal Health Identification Number; HCV-RNA; Hepatitis C Virus Ribonucleic Acid; SAS; Statistical Ana
Molecular characterization of the type I IFN receptor in two woodchuck species and detection of its expression in liver samples from woodchucks infected with woodchuck hepatitis virus (WHV)
Keywords: هپاتیت سی; Type I interferon receptor; Woodchuck; Marmota monax; Marmota himalayana; Woodchuck hepatitis virus; IFN; interferon; ISG; IFN-stimulated genes; IFNAR; type I IFN receptor; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HMGB1; high-mobility group
Research ArticlePreventive versus “on-demand” nutritional support during antiviral treatment for hepatitis C: A randomized controlled trial
Keywords: هپاتیت سی; HCV; hepatitis C virus; HGS; hand-grip strength; MAMC; mid-arm muscle circumference; TSF; triceps skin fold thickness; VAS; visual analogue scale; HOMA index; homeostasis model assessment index; SVR; sustained viral response; SF-36 Survey; Short-Form-36 S
Research ArticleHepatitis C virus non-structural 5B protein interacts with cyclin A2 and regulates viral propagation
Keywords: هپاتیت سی; HCV; hepatitis C virus; NS5A; non-structural 5A; NS5B; non-structural 5B; HCC; hepatocellular carcinoma; CycA2; cyclin A2; CDK1&2; cyclin-dependent kinase 1&2; GST; glutathione S-transferase; PBS; phosphate-buffered saline; TRITC; tetramethylrhodamine iso
Research ArticleFatigue before, during and after antiviral therapy of chronic hepatitis C: Results from the Virahep-C study
Keywords: هپاتیت سی; HCV; hepatitis C virus; AA; African American; CA; Caucasian American; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BMI; body mass index; SVR; sustained virological response; NR; non-response; VAS; visual analog scale; HRQoL; health rela
Research ArticleDiscordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe
Keywords: هپاتیت سی; Biomarker; Biopsy; Fibrosis; Stiffness; ALT; alanine aminotransferase; APRI; AST to platelet ratio index; AST; aspartate aminotransferase; AUROC; area under the receiver operating characteristic curve; CI; confidence interval; HBV; hepatitis B virus; HCV;
Research ArticleSingle nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1
Keywords: هپاتیت سی; AA; African American(s); CA; Caucasian American(s); EVR; early virologic response; CI; confidence interval; D28; day 28; HCV; hepatitis C virus; IFN; interferon; BMI; body mass index; HOMA-IR; homeostasis model assessment for insulin resistance; NR; nonre
Research ArticleSurvival after radiofrequency ablation and salvage transplantation in patients with hepatocellular carcinoma and Child-Pugh A cirrhosis
Keywords: هپاتیت سی; Primary liver cancer; Hepatoma; Percutaneous ablation; Liver graft; Recurrence; HCC; hepatocellular carcinoma; RFA; radiofrequency ablation; LR; liver resection; LT; liver transplantation; HCV; hepatitis C virus; AFP; α-fetoprotein; HBV; hepatitis B viru
Research ArticleInterleukin-28B genetic variants in identification of hepatitis C virus genotype 1 patients responding to 24 weeks peginterferon/ribavirin
Keywords: هپاتیت سی; HCV; hepatitis C virus; CHC; chronic hepatitis C; GWAS; genome-wide associated studies; SNP; single nucleotide polymorphism; IL-28B; interleukin 28B; SVR; sustained virological response; RVR; rapid virological response; EOTVR; end-of-treatment virological
Research ArticleTumor progression-related transmembrane protein aspartate-β-hydroxylase is a target for immunotherapy of hepatocellular carcinoma
Keywords: هپاتیت سی; HCC; hepatocellular carcinoma; ASPH; aspartate-β-hydroxylase; DCs; dendritic cells; TILs; tumor infiltrating lymphocytes; PBMCs; peripheral blood mononuclear cells; HBV; hepatitis B; HCV; hepatitis C; CTLs; cytotoxic T lymphocytes; TAAs; tumor-associated
Research ArticleHigh intrahepatic HHV-6 virus loads but neither CMV nor EBV are associated with decreased graft survival after diagnosis of graft hepatitis
Keywords: هپاتیت سی; HHV-6; human herpes virus type 6; CMV; cytomegalovirus; EBV; Epstein Barr virus; HCV; hepatitis C virus; HBV; hepatitis B virus; AST; aspartate aminotransferase; ALT; alanine aminotransferase; GGT; gamma glutamyltransferase; AP; alcaline phosphatase; HHV-
Research ArticleA randomized trial of 48 versus 24 weeks of combination pegylated interferon and ribavirin therapy in genotype 6 chronic hepatitis C
Keywords: هپاتیت سی; HCV; hepatitis C virus; ALT; alanine aminotransferase; AST; aspartate aminotransferase; PEG-IFN; pegylated interferon; RBV; ribavirin; SVR; sustained virological response; RVR; rapid virological response; cEVR; complete early virological response; ETR; en
Absorption and metabolism of milk thistle flavanolignans in humans
Keywords: هپاتیت سی; HCV; hepatitis C virus; ESI; electrospray interface; MRM; multiple reaction monitoring; UDP; uridine diphosphate; UGTs; UDP-glucuronosyltransferases; SULTs; sulphotransferases; EHR; entero-hepatic recirculation; amu; atomic mass unit; Flavanolignans; Urin
Effects of alcohol on pericardial adhesion formation in hypercholesterolemic swine
Keywords: هپاتیت سی; 32; 38.2; 40.3; ANOVA; analysis of variance; CRP; C-reactive protein; ECM; extracellular matrix; FAK; focal adhesion kinase; HCC; high-cholesterol control; HCV; high-cholesterol vodka; HCW; high-cholesterol wine; Int α5; integrin alpha-5; Int β1; integr
Chronic HCV infection is a risk of atherosclerosis. Role of HCV and HCV-related steatosis
Keywords: هپاتیت سی; CHC; chronic hepatitis C; IMT; carotid intima-media thickness; HOMA-IR; homeostatic model assessment; IR; insulin resistance; HCV; hepatitis C virus; HCV RNA; hepatitis C virus RNA; HAI; histological activity index; CRP; C reactive protein; HCV; Carotid a