Delineating the Phenotypic Spectrum of the NTHL1-Associated Polyposis
Keywords: سرطان روده بزرگ; CRC; colorectal cancer; ExAC; Exome Aggregation Consortium;
مقالات ISI سرطان روده بزرگ (ترجمه نشده)
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Original ResearchAutophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials
Keywords: سرطان روده بزرگ; Autophagy; Hypertension; Colorectal cancer; Single-nucleotide polymorphism; Bevacizumab-associated toxicity; FOLFIRI/bevacizumab;
The effect of O-GlcNAcylation on hnRNP A1 translocation and interaction with transportin1
Keywords: سرطان روده بزرگ; CRC; colorectal cancer; CTD; carboxyl terminal domain; GlcNAc; N-acetylglucosamine; hnRNP A1; heterogenous nuclear ribonucleoprotein A1; OGA; O-GlcNAcase; OGT; O-GlcNAc transferase; Ser; serine; sWGA; succinylated wheat germ agglutinin; Thr; threonine; TM
Short CommunicaitonTumor regression grades, K-RAS mutational profile and c-MET in colorectal liver metastases
Keywords: سرطان روده بزرگ; Colorectal cancer; Liver metastasis; K-RAS; C-MET;
Expression of A-kinase anchor protein 13 and Rho-associated coiled-coil containing protein kinase in restituted and regenerated mucosal epithelial cells following mucosal injury and colorectal cancer cells in mouse models
Keywords: سرطان روده بزرگ; AKAP13; A-kinase anchor protein 13; AOM; azoxymethane; CRC; colorectal cancer; DSS; dextran sodium sulfate; ERK; extracellular signal-regulated kinase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GEF; guanine nucleotide exchange region; H&E; hematoxy
The clinical value and biological function of PTTG1 in colorectal cancer
Keywords: سرطان روده بزرگ; PTTG1; Biomarker; Colorectal cancer; Proliferation; Metastasis;
SIRT2 mediated antitumor effects of shikonin on metastatic colorectal cancer
Keywords: سرطان روده بزرگ; SIRT2; Shikonin; Colorectal cancer; Metastasis; Phospho-extracellular signal-regulated kinases (p-ERK);
Discovery of a novel pan-RAF inhibitor with potent anti-tumor activity in preclinical models of BRAFV600E mutant cancer
Keywords: سرطان روده بزرگ; Pan-RAF inhibitor; BRAFV600E mutant; RAS mutant; Melanoma; Colorectal cancer;
Midkine is up-regulated in both cancerous and inflamed bowel, reflecting lymph node metastasis in colorectal cancer and clinical activity of ulcerative colitis
Keywords: سرطان روده بزرگ; Midkine; Colorectal cancer; Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; Surgical stress;
Isofraxidin inhibited proliferation and induced apoptosis via blockage of Akt pathway in human colorectal cancer cells
Keywords: سرطان روده بزرگ; Isofraxidin; Colorectal cancer; Akt; Proliferation; Apoptosis;
Chitosan nanoparticles as a dual drug/siRNA delivery system for treatment of colorectal cancer
Keywords: سرطان روده بزرگ; siRNA; small interfering RNA; CMD; carboxymethyl dextran; DOX; doxorubicin; ChNPs; nanoparticles; EMT; Epithelial mesenchymal transition; CRC; colorectal cancer; MMPs; matrix metalloproteinases; FTIR; Fourier transform infrared spectroscopy; FBS; fetal bo
Beta-catenin and p53 expression in topographic compartments of colorectal cancer and its prognostic value following surgery
Keywords: سرطان روده بزرگ; Colorectal cancer; Immunohistochemistry; p53; β-Catenin; Topographic compartments; Survival;
Original contributionIntramucosal colorectal carcinoma with invasion of the lamina propria: a study by the Japanese Society for Cancer of the Colon and Rectum
Keywords: سرطان روده بزرگ; Colorectal cancer; Intramucosal adenocarcinoma; Lamina propria; pTia; Early colorectal cancer;
Research paperWhole liver CT texture analysis to predict the development of colorectal liver metastases-A multicentre study
Keywords: سرطان روده بزرگ; AUC; area under the ROC curve; CEA; carcinoembryonic antigen; CRC; colorectal cancer; CT; computed tomography; E; entropy; LoG; Laplacian of Gaussian; M; mean grey-level intensity; MRI; magnetic resonance imaging; N-stage; nodal stage; OR; odds ratio; PET
Original ResearchDoes tumor size have its prognostic role in colorectal cancer? Re-evaluating its value in colorectal adenocarcinoma with different macroscopic growth pattern
Keywords: سرطان روده بزرگ; Colorectal cancer; Macroscopic growth pattern; Tumor size; Overall survival; Disease-free survival;
Butyrate suppresses motility of colorectal cancer cells via deactivating Akt/ERK signaling in histone deacetylase dependent manner
Keywords: سرطان روده بزرگ; Butyrate; Colorectal cancer; Motility; Histone deacetylase; Metastasis;
The Cost of Colorectal Cancer According to the TNM Stage
Keywords: سرطان روده بزرگ; Colorectal cancer; Clinical stage; Costs; Survival; Burden; Cáncer colorrectal; Estadio clÃnico; Costes; Supervivencia; Carga económica;
Original ArticleThe tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton
Keywords: سرطان روده بزرگ; Colorectal cancer; Homeobox gene; Metastasis; Stress fibers; Cellular stiffness;
Polysaccharide from Lycium barbarum L. leaves enhances absorption of endogenous calcium, and elevates cecal calcium transport protein levels and serum cytokine levels in rats
Keywords: سرطان روده بزرگ; CAT1; calcium transporter 1; CRC; colorectal cancer; DMT1; divalent metal transporter; DP; the degraded LP in rat cecum; FAAS; atomic absorption spectrometry; FBS; fetal bovine serum; FID; flame ionization detector; FTIR; Fourier transform infrared; GLs;
Development of an enzyme-linked immunosorbent assay for detection of CDCP1 shed from the cell surface and present in colorectal cancer serum specimens
Keywords: سرطان روده بزرگ; ELISA; CDCP1; Colorectal cancer;
Identification of actin beta-like 2 (ACTBL2) as novel, upregulated protein in colorectal cancer
Keywords: سرطان روده بزرگ; ACTBL2; Colorectal cancer; Mass spectrometric analysis; Two-dimensional gel electrophoresis; Protein biomarkers;
Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells
Keywords: سرطان روده بزرگ; B. serrata extract; Colorectal cancer; Microsomal prostaglandin E synthase-1; Prostaglandin E2;
Natural history of diminutive and small colorectal polyps: a systematic literature review
Keywords: سرطان روده بزرگ; CRC; colorectal cancer; HGD; high-grade dysplasia; HP; hyperplastic polyp; SSP; sessile serrated polyp;
GC-MS based metabolomics of colon cancer cells using different extraction solvents
Keywords: سرطان روده بزرگ; Colon cancer; Sample treatment; Metabolomics; Gas chromatography-mass spectrometry; GC-MS; CRC; colorectal cancer; MSEA; metabolite set enrichment analysis; MPA; metabolic pathway analysis; MSTFA; N-methyl-N-(trimethylsilyl)-trifluoroacetamide; ORA; overr
Multi-detector CT: Liver protocol and recent developments
Keywords: سرطان روده بزرگ; ALP; arterial liver perfusion; BV; blood volume; BW; body weight; CLD; chronic liver disease; CM; contrast medium; CNR; contrast-to-noise ratio; CRC; colorectal cancer; DECT; Dual-energy CT; EAP; early arterial phase; HCC; hepatocellular carcinoma; HPI; h
Is Ep-CAM Expression a Diagnostic and Prognostic Biomarker for Colorectal Cancer? A Systematic Meta-Analysis
Keywords: سرطان روده بزرگ; CRC; colorectal cancer; CSC; cancer stem cell; Ep-CAM; epithelial cell adhesion molecule; OR; odds ratio; HR; hazard ratio; 95% CI; 95% confidence interval; AUC; area under the curve; DFS; disease-free survival; DSS; disease-specific survival; OS; overall
Fecal Clostridium symbiosum for Noninvasive Detection of Early and Advanced Colorectal Cancer: Test and Validation Studies
Keywords: سرطان روده بزرگ; Colorectal cancer; Early diagnosis; Clostridium symbiosum; Quantitative PCR;
Original contributionTumor budding as a risk factor for nodal metastasis in pT1 colorectal cancers: a meta-analysisâ
Keywords: سرطان روده بزرگ; Tumor budding; Sprouting; Colorectal cancer; Lymph node metastasis; Meta-analysis;
Original contributionTumor budding at the invasive front of colorectal cancer may not be associated with the epithelial-mesenchymal transition
Keywords: سرطان روده بزرگ; Colorectal cancer; Epithelial-mesenchymal transition; Tumor budding; TWIST; ZEB1;
In this issueUtility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer
Keywords: سرطان روده بزرگ; HER2; Colorectal cancer; Next-generation sequencing; Comprehensive genomic sequencing; Immunohistochemistry; Fluorescence in situ hybridization;
Robotic right hemicolectomy: Analysis of 108 consecutive procedures and multidimensional assessment of the learning curve
Keywords: سرطان روده بزرگ; Robotic colectomy; Right hemicolectomy; Learning curve; Cumulative sum analyses; Colon cancer; Colorectal cancer; Ileocolic anastomosis;
Proximal signaling responses in peripheral T cells from colorectal cancer patients are affected by high concentrations of circulating prostaglandin E2
Keywords: سرطان روده بزرگ; BD; blood donors; CEA; carcinoembryonic antigen; COX; cyclooxygenase; CRC; colorectal cancer; FCB; fluorescence cell barcoding; ITAM; immunoreceptor tyrosine based activation motif; MFI; median fluorescence intensity; ND; not determined; NSAID; non-steroi
Original ResearchClinical and molecular characterisation of hereditary and sporadic metastatic colorectal cancers harbouring microsatellite instability/DNA mismatch repair deficiency
Keywords: سرطان روده بزرگ; Microsatellite instability; Mismatch repair; Lynch syndrome; BRAF mutation; Immunotherapy; Colorectal cancer;
Survival after recurrence of stage I-III breast, colorectal, or lung cancer
Keywords: سرطان روده بزرگ; Recurrence; Survival; Outcomes; Natural history; Breast cancer; Lung cancer; Colorectal cancer;
Original ResearchResection of colorectal liver metastases after second-line chemotherapy: is it worthwhile? A LiverMetSurvey analysis of 6415 patients
Keywords: سرطان روده بزرگ; Colorectal cancer; Liver metastasis; Preoperative chemotherapy; Second line; Hepatectomy;
Mini-reviewCo-targeting of EGFR and autophagy signaling is an emerging treatment strategy in metastatic colorectal cancer
Keywords: سرطان روده بزرگ; Colorectal cancer; Epidermal growth factor receptor; Autophagy; Endocytosis; Panitumumab; Cetuximab;
Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model
Keywords: سرطان روده بزرگ; Colorectal cancer; PEG-coated shRNA-lipoplex; RNAi; S-1; Short hairpin RNA; Thymidylate synthase;
The endocrine vitamin D system in the gut
Keywords: سرطان روده بزرگ; Vitamin D; Gut homeostasis; Inflammatory bowel diseases; Gut microbiota; Colorectal cancer; 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; CDX-2; Caudal-related homeobox transcription factor 2; CRC; Colon/colorectal cancer; IBD; Inflammatory bowel diseases; IL;
Ezrin/NF-kB activation regulates epithelial- mesenchymal transition induced by EGF and promotes metastasis of colorectal cancer
Keywords: سرطان روده بزرگ; CRC; colorectal cancer; EMT; Epithelial-mesenchymal transition; qRT-PCR; quantitative real-time polymerase chain reaction; IHC; immuno-histochemistry; IF; Immunofluorescence staining; Ezrin/NF-kB activation; Epithelial-mesenchymal transition; Colorectal c
Original ArticleRufy3 promotes metastasis through epithelial-mesenchymal transition in colorectal cancer
Keywords: سرطان روده بزرگ; Rufy3; Colorectal cancer; Metastasis; Epithelial-mesenchymal transition; TGF-β1; EMT; epithelial-mesenchymal transition; Si RNA; short interfering RNA; ChIP; chromatin immunoprecipitation; RLU; relative luciferase unit; 5-FU; 5-fluorouracil;
Original ArticleSRC activates TAZ for intestinal tumorigenesis and regeneration
Keywords: سرطان روده بزرگ; SRC; TAZ; APC; Colorectal cancer; Regeneration;
Co-expression of TIM-3 and CEACAM1 promotes T cell exhaustion in colorectal cancer patients
Keywords: سرطان روده بزرگ; TIM-3; T-cell immunoglobulin domain and mucin domain-3; CEACAM1; carcinoembryonic antigen cell adhesion molecule 1; CRC; colorectal cancer; TIL; tumor infiltrating lymphocytes; CEA; carcinoembryonic antigen; Colorectal cancer; TIM-3; CEACAM1; Immunosuppre
Bile acids and colon cancer: Is FXR the solution of the conundrum?
Keywords: سرطان روده بزرگ; Bile acids; Nuclear receptors; Colorectal cancer; Gene expression; Gut-liver axis;
Cáncer colorrectal en el anciano. Tratamiento quirúrgico, quimioterápico y aportación desde la geriatrÃa
Keywords: سرطان روده بزرگ; Anciano; Cáncer colorrectal; Tratamiento; OncogeriatrÃa; Elderly; Colorectal cancer; Treatment; Oncogeriatrics;
Original ArticleThioredoxin-1 promotes colorectal cancer invasion and metastasis through crosstalk with S100P
Keywords: سرطان روده بزرگ; Thioredoxin-1; Colorectal cancer; S100P; Metastasis; ChIP; chromatin immunoprecipitation; CRC; colorectal cancer; DAPI; 4â²-6-Diamidino-2-phenylindole; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; IF; immunofluorescence; IHC; immunohistochemistry; PC
Yacon flour (Smallanthus sonchifolius) attenuates intestinal morbidity in rats with colon cancer
Keywords: سرطان روده بزرگ; YF; yacon flour; CRC; colorectal câncer; FOS; fructooligosaccharides; SCFA; short-chain fatty acids; ACF; aberrant crypts focus; Fructooligosaccharides; Prebiotics; Intestinal permeability; SCFA; pH;
The fermented non-digestible fraction of spent coffee grounds induces apoptosis in human colon cancer cells (SW480)
Keywords: سرطان روده بزرگ; A; apical; ABTS; 2,2â²-azinobis (3-ethylbenzothiazoline-6-sulfonic acid); AA; antioxidant activity; B; basolateral; BSA; bovine serum albumin; bis-AAF-R110; bis-alanylalanyl-phenylalanyl- rhodamine 110; CRC; colorectal cancer; CB; coffee beans; DAD; diod
Impact of fixation artifacts and threshold selection on high resolution melting analysis for KRAS mutation screening
Keywords: سرطان روده بزرگ; Colorectal cancer; KRAS mutations; High resolution melting; Fixation artifacts; Melting threshold; Screening; Predictive biomarker;
Cystic Fibrosis & disorders of the large intestine: DIOS, constipation, and colorectal cancer
Keywords: سرطان روده بزرگ; Distal intestinal obstruction syndrome; DIOS; Constipation; Colorectal cancer; Colon cancer; Colon; Colonoscopy; Cystic fibrosis; Gastroenterology;
HNE and cholesterol oxidation products in colorectal inflammation and carcinogenesis
Keywords: سرطان روده بزرگ; 7K; 7-ketocholesterol; 7βOH; 7β-hydroxycholesterol; 22OH; 22-hydroxycholesterol; 24OH; 24-hydroxycholesterol; 25OH; 25-hydroxycholesterol; 27OH; 27-hydroxycholesterol; 8-OHdG; 8-hydroxy-2â²-deoxyguanosine; Akt; AKT serine/threonine kinase 1; AP-1; acti