The role of IκB kinase complex in the neurobiology of Huntington's disease
Keywords: التهاب عصبی; Huntington's disease; IKKβ; Neuroinflammation; Htt cleavage; DNA damage
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S100B brain expression and plasma concentrations in a preeclampsia rat model
Keywords: التهاب عصبی; Preeclampsia; Neuroinflammation; PRES; S100B; Animal model
Augmented expression of glia maturation factor in Alzheimer's disease
Keywords: التهاب عصبی; Alzheimer's disease (AD); glia maturation factor (GMF); amyloid plaques (APs); neurofibrillary tangles (NFTs); neuroinflammation; neurodegenerationAD, Alzheimer's disease; AP, amyloid plaques; ELISA, enzyme-linked immunosorbent assay; ENT Cx, entorhinal c
Bilirubin Injury to Neurons and Glial Cells: New Players, Novel Targets, and Newer Insights
Keywords: التهاب عصبی; astrocyte and microglia reactivity; neurodegeneration; neuroinflammation; neuron-glia interplay; oligodendrocytes; RNS; ROS; unconjugated bilirubin
Anti-inflammatory effects of [6]-shogaol: Potential roles of HDAC inhibition and HSP70 induction
Keywords: التهاب عصبی; CNS; central nervous system; COX-2; cyclooxygenase-2; GFAP; glial fibrillary acidic protein; HSP; heat-shock protein; HDAC; histone deacetylase; iNOS; inducible nitric oxide syntheses; LPS; lipopolysaccharide; MEM; minimal essential media; MS; MS-275; TSA
Cytokines and neuronal channels: A molecular basis for age-related decline of neuronal function?
Keywords: التهاب عصبی; Aging; Cytokines; Neuroinflammation; Ion channel; IL-1β
ReviewProstanoid signaling: Dual role for prostaglandin E2 in neurotoxicity
Keywords: التهاب عصبی; Prostaglandin E2; E Prostanoid receptor; Arachidonic acid; Neurotoxicity; Neuroinflammation;
Mesenchymal stem cell transplantation modulates neuroinflammation in focal cerebral ischemia: Contribution of fractalkine and IL-5
Keywords: التهاب عصبی; Cerebral ischemia; Mesenchymal stem cell; Neuroinflammation; Fractalkine; IL-5; Immunomodulation
Hypobaric Hypoxia Exacerbates the Neuroinflammatory Response to Traumatic Brain Injury
Keywords: التهاب عصبی; traumatic brain injury; inflammation; neuroinflammation; aeromedical evacuation; hypobaric; hypoxia
The age- and amyloid-β-related increases in Nogo B contribute to microglial activation
Keywords: التهاب عصبی; Nogo; Hippocampus; Amyloid-β; Age; Neuroinflammation; Microglial activation; Synaptic deterioration; Caspase; Long term potentiation
Differential regulation of C-terminal splice variants of the glutamate transporter GLT-1 by tumor necrosis factor-alpha in primary cultures of astrocytes
Keywords: التهاب عصبی; GLT-1a; GLT-1b; Astrocytes; Alternative splicing; Neuroinflammation; Tumor necrosis factor-alpha
Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: The positive effect of long-term aspirin treatment
Keywords: التهاب عصبی; MPS IIIA; Mucopolysaccharidosis (MPS) type IIIA, Sanfilippo disease type A; LSD; Lysosomal storage diseases; GAGs; Glycosaminoglycans; CNS; Central nervous system; GFAP; Glial fibrillary acidic protein; NSAIDs; Nonsteroidal anti-inflammatory drugs; PCR; P
Research ReportTetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42)
Keywords: التهاب عصبی; AD; Alzheimer's disease; Aβ; amyloid-β; IL; interleukin; TNF; tumor necrosis factor; NF-κB; nuclear factor-κB; TET; tetrandrine; Alzheimer's disease; Amyloid-β; Morris water maze test; Neuroinflammation; Tetrandrine; NF-κB;
Microinjection of l-arginine into corpus callosum cause reduction in myelin concentration and neuroinflammation
Keywords: التهاب عصبی; l-Arginine; Nitric oxide; Corpus callosum; Neuroinflammation; Demyelination; Multiple sclerosis
Astrocytes in the tempest of multiple sclerosis
Keywords: التهاب عصبی; Astrocyte; Neuroinflammation; Multiple sclerosis; Blood-brain barrier; Extracellular matrix;
Stress- and glucocorticoid-induced priming of neuroinflammatory responses: Potential mechanisms of stress-induced vulnerability to drugs of abuse
Keywords: التهاب عصبی; Stress; Glucocorticoid; Neuroinflammation; Cytokine; Addiction
Efficacy of post-insult minocycline administration to alter long-term hypoxia-ischemia-induced damage to the serotonergic system in the immature rat brain
Keywords: التهاب عصبی; hypoxia-ischemia; minocycline; neonate; neuroinflammation; raphé neuron; serotoninHI, hypoxia-ischemia; Iba-1, ionized calcium binding adapter molecule-1; IL-1β, interleukin-1β; P, post-natal day; SERT, serotonin transporter; TNF-α, tumor necrosis factor-
Thymulin related peptide attenuates inflammation in the brain induced by intracerebroventricular endotoxin injection
Keywords: التهاب عصبی; Neuroinflammation; Thymulin; Cytokines; Neurotrophins; Analgesia; Hyperalgesia; CNS; Central nervous system; ET; Endotoxin; HP; Hot plate; IL; Interleukin; ICV; Intracerebroventricular; i.p.; Intraperitoneal; PWL; Paw withdrawal latency; PWT; Paw withdraw
Macrophage migration inhibitory factor activates cyclooxygenase 2-prostaglandin E2 in cultured spinal microglia
Keywords: التهاب عصبی; CNS; central nervous system; COX 2; cyclooxygenase 2; ERK; extracellular signal regulated kinase; ISO-1; ((S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester; MAPK; mitogen activated protein kinase; MIF; macrophage migration inhibi
Minocycline promotes remyelination in aggregating rat brain cell cultures after interferon-γ plus lipopolysaccharide-induced demyelination
Keywords: التهاب عصبی; neuroinflammation; microglia; oligodendrocyte precursor cells; DIV; day in vitro; IB4; isolectin B4 of Griffonia simplicifolia; IFN-γ; interferon-γ; LPS; lipopolysaccharide; MAP; mitogen-activated protein; MBP; myelin basic protein; MOG; myelin oligoden
Social disruption induced priming of CNS inflammatory response to Theiler's virus is dependent upon stress induced IL-6 release
Keywords: التهاب عصبی; Multiple sclerosis; TMEV; SDR; Stress; IL-6; Neuroinflammation
Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6
Keywords: التهاب عصبی; Protein expression; Neuronal development; Cytokine; Transgenic mice; Neuroinflammation
Inverse agonism of cannabinoid CB1 receptor blocks the adhesion of encephalitogenic T cells in inflamed brain venules by a protein kinase A-dependent mechanism
Keywords: التهاب عصبی; Cannabinoid CB1 receptor; Neuroinflammation; Lymphocyte trafficking; Integrins; Protein kinase A;
Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GNDF in astroglia
Keywords: التهاب عصبی; Parkinson’s disease; In vitro model; Neurodegenerative disease; Neuroinflammation; Neuroprotection; MPP+; LPSPD, Parkinson’s disease; DA, dopamine; TH, tyrosine hydroxylase; NMDAr, N-methyl-d-aspartate receptor; LPS, lipopolysaccharide; GDNF, glial cell l
Interleukin 4 induces the apoptosis of mouse microglial cells by a caspase-dependent mechanism
Keywords: التهاب عصبی; Microglia; Interleukin 4; Apoptosis; Caspases; Neuroinflammation;
Adolescent binge alcohol exposure induces long-lasting partial activation of microglia
Keywords: التهاب عصبی; Adolescence; Alcoholism; Ethanol; Hippocampus; Microglial activation; Neurodegeneration; Neuroinflammation
Wallerian degeneration and peripheral nerve conditions for both axonal regeneration and neuropathic pain induction
Keywords: التهاب عصبی; Nerve injury; Activated Schwann cells; Macrophages; Neuroinflammation; Neurotrophins; Cytokines; Chemokines;
Increased activity of Th-17 and Th-9 lymphocytes and a skewing of the post-thymic differentiation pathway are seen in Alzheimer's disease
Keywords: التهاب عصبی; Alzheimer's disease; Neuroinflammation; T helper lymphocytes; Th-17; Th-9; Memory/naïve lymphocytes;
Innate and adaptive immunity in amyotrophic lateral sclerosis: Evidence of complement activation
Keywords: التهاب عصبی; SC; spinal cord; MCx; motor cortex; WM; white matter; VH; ventral horn; MG; microglia; IR; immunoreactivity; Neuroinflammation; Complement system; Amyotrophic Lateral Sclerosis;
A simple magnetic separation method for high-yield isolation of pure primary microglia
Keywords: التهاب عصبی; Cell culture; Microglia; Microglial isolation; Microglial activation; Magnetic separation; Neuroinflammation; Neurodegeneration; Parkinson's disease;
Fluorinated cannabinoid CB2 receptor ligands: Synthesis and in vitro binding characteristics of 2-oxoquinoline derivatives
Keywords: التهاب عصبی; Central nervous system; Cannabinoid receptor 2; Multiple sclerosis; Neuroinflammation; Neurodegeneration;
Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults
Keywords: التهاب عصبی; neurodegeneration; neuroinflammation; endocannabinoids; beta-amyloid; monoacylglycerol lipase; Alzheimer's diseaseAD, Alzheimer's disease; Aβ, β-amyloid peptide; CAP, capsazepine; CB1R, CB1 receptor; COX-2, cyclooxygenase-2; eCBs, endocannabinoids; MAGL,
Inhibition of lipopolysaccharide-induced microglia activation by calcitonin gene related peptide and adrenomedullin
Keywords: التهاب عصبی; Neuroinflammation; Tumor necrosis factor α; Chemokines; cAMP; PGE2;
Increased expression of acyl-coenzyme A: cholesterol acyltransferase-1 and elevated cholesteryl esters in the hippocampus after excitotoxic injury
Keywords: التهاب عصبی; cholesterol; cholesteryl esters; neuroinflammation; cholesterol oxidation products; oxidative stress; ACAT1ACAT, acyl-coenzyme A: cholesterol acyltransferase; CNPase, 2′,3′-cyclic nucleotide 3′-phosphodiesterase; KA, kainate; NMR, nuclear magnetic resonan
Transcriptional control of maladaptive and protective responses in alcoholics: A role of the NF-κB system
Keywords: التهاب عصبی; Alcoholism; Dependence; Addiction; Neuroinflammation; Neuroplasticity; Gene transcription; Transcription factors; NF-κB; p50; Human brain
Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damage
Keywords: التهاب عصبی; 5-Lipoxygenase; Leukotriene; Multiple sclerosis; Cuprizone; Demyelination; Neuroinflammation; Axonal damage;
Radical changes in multiple sclerosis pathogenesis
Keywords: التهاب عصبی; Antioxidants; Multiple sclerosis; Neurodegeneration; Neuroinflammation; Oxidative damage; Reactive oxygen species
S-Propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuates lipopolysaccharide-induced spatial learning and memory impairment: Involvement of TNF signaling and NF-κB pathway in rats
Keywords: التهاب عصبی; Alzheimer’s disease; S-Propargyl-cysteine; Hydrogen sulfide; Learning; Memory; Neuroinflammation
Early and adult hippocampal TGF-β1 overexpression have opposite effects on behavior
Keywords: التهاب عصبی; Transforming Growth Factor-beta 1; Autism; Neuroinflammation; Postnatal programming; Mice; Behavior
HIV-1 infection and alcohol abuse: Neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions
Keywords: التهاب عصبی; HIV-1; Alcohol abuse; Neuroinflammation; Cannabinoid receptor 2; Glial cells; Blood–brain barrier
Effects of d-cycloserine on MPTP-induced behavioral and neurological changes: Potential for treatment of Parkinson's disease dementia
Keywords: التهاب عصبی; Parkinson's disease; NMDA receptor; d-Cycloserine; Dementia; Neuroinflammation; Cognition
An angiogenic inhibitor, cyclic RGDfV, attenuates MPTP-induced dopamine neuron toxicity
Keywords: التهاب عصبی; Blood brain barrier; ZO-1; Neuroinflammation; Microglia; Parkinson's disease; Disease progression; Angiogenesis
Neuroinflammation and the plasticity-related immediate-early gene Arc
Keywords: التهاب عصبی; Synaptic plasticity; Learning and memory; Immediate-early gene; Arc; Neuroinflammation; Innate immune system; Cytokines; Neuronal networks; Fractalkine; Hippocampal circuits
Neurodegeneration, Neuroprotection, and Disease-Oriented NeuroscienceResearch PaperTime-course of nigrostriatal neurodegeneration and neuroinflammation in the 6-hydroxydopamine-induced axonal and terminal lesion models of Parkinson's disease in the rat
Keywords: التهاب عصبی; Parkinson's disease; neuroinflammation; 6-hydroxydopamine; striatum; substantia nigra; GFAP; glial fibrillary acidic protein; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; TH; tyrosine hydroxylase;
LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyamine-dependent
Keywords: التهاب عصبی; ApoD; apolipoprotein D; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; CNP; 2â²,3â²-cyclic nucleotide 3â²-phophodiesterase; CNS; central nervous system; Ct; comparative cycle threshold; DMEM; Dubecco's modified Eagle's medium; DFMO; α-
MicroRNA changes in the mouse prefrontal cortex after inflammatory pain
Keywords: التهاب عصبی; miRNA; Cerebral cortex; Frontal cortex; Orofacial pain; Inflammation; Nociception; Antinociception; Neuroinflammation; Neutrophils;
Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage
Keywords: التهاب عصبی; Ethanol; TLR4; Neuroinflammation; Locomotor activity; Object memory recognition; Conditioned taste aversion; Dark and light box; Histone acetylation
Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation
Keywords: التهاب عصبی; Neuroinflammation; Microglia; Cytokines; Cytochrome P450; Leukotriene
Attenuated neurological deficit, cell death and lesion volume in Fas-mutant mice is associated with altered neuroinflammation following traumatic brain injury
Keywords: التهاب عصبی; Cell death; Caspase; Cytokine; Fas; Neuroinflammation; Traumatic brain injury
Rosiglitazone decreases peroxisome proliferator receptor-gamma levels in microglia and inhibits TNF-alpha production: new evidences on neuroprotection in a progressive Parkinson's disease model
Keywords: التهاب عصبی; PPAR-gamma; neuroprotection; MPTP; neuroinflammation; microglia; TNF-alphaDA, dopamine; DOPAC, 3,4-dihydroxyphenylacetic acid; TZD, thiazolidinedione; MPTPp, MPTP/probenecid; PD, Parkinson's disease; PPAR-γ, proliferator-activated receptor gamma; TH, tyro