Dynamic control of type I IFN signalling by an integrated network of negative regulators
Keywords: اینترفرون; Interferon; cytokine; STAT; JAK; SOCS;
مقالات ISI اینترفرون (ترجمه نشده)
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Muscovy duck reovirus infection rapidly activates host innate immune signaling and induces an effective antiviral immune response involving critical interferons
Keywords: اینترفرون; Muscovy duck reovirus; Interferon; Pathogen-recognition receptors; Innate immunity; Waterfowl;
Antifibrotic mechanism of deferoxamine in concanavalin A induced-liver fibrosis: Impact on interferon therapy
Keywords: اینترفرون; Deferoxamine mesylate (PubChem CID: 62881); Interferon α2b (PubChem CID: 71306834); Concanavalin A (PubChem CID: 135337769); Chloramine-T (PubChem CID: 50055044); Ehlrich’s reagent (PubChem CID: 49874978)Liver fibrosis; Iron; Deferoxamine; Interferon; Hep
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues
Keywords: اینترفرون; ADPR; ADP ribose; ARTs; ADP ribose transferases; ARTD1; poly-(ADP ribose) polymerase 1; NAADP; nicotinic acid adenine dinucleotide phosphate; CR; calorie restriction; PAR; poly-(ADP ribose); PGC-1; peroxisome proliferator-activated receptor-γ coactivator
Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha
Keywords: اینترفرون; CNTF(R); Ciliary neurotrophic factor (receptor); EGF; Epidermal growth factor; ERK; Extracellular signal-regulated kinase; FRα; Folate receptor alpha; GPI; glycophosphatidylinositol; IFN; Interferon; IL-6(R); Interleukin 6 (receptor); ISG; Interferon sti
Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C
Keywords: اینترفرون; Interferon; Viral; IFN-β; IFN-α; IL-6; Sickness; Behaviour; Hypoactivity; Depression; Cytokine; Neuroinflammation; Hippocampus; IDO; Kynurenine; STAT1; Burrowing;
Basal buffer systems for a newly glycosylated recombinant human interferon-β with biophysical stability and DoE approaches
Keywords: اینترفرون; Interferon; Design of experiment (DoE); Differential Scanning Calorimetry (DSC); FT-IR; Protein formulation; Biobetter
Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets
Keywords: اینترفرون; Atherosclerosis; Cytokines; Chemokines; Inflammation; Therapeutic avenues; ABC; ATP-binding cassette; ACAT-1; acyl-CoA acyl transferase-1; ADRP; adipocyte differentiation related protein; Apo; apolipoprotein; BMT; bone marrow transplantation; CANTOS; Cana
Evolving Therapeutic Options for Polycythemia Vera: Perspectives of the Canadian Myeloproliferative Neoplasms Group
Keywords: اینترفرون; Hydroxyurea; Interferon; JAK2 mutation; Polycythemia vera; Ruxolitinib
Original scientific articleLaparoscopic Splenectomy with Technical Standardization and Selection Criteria for Standard or Hand-Assisted Approach in 390 Patients with Liver Cirrhosis and Portal Hypertension
Keywords: اینترفرون; AT; antithrombin; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IFN; interferon; LS; laparoscopic splenectomy; OPSI; overwhelming post-splenectomy infection; OR; odds ratio; PVT; portal vein thrombosis; SVD; splenic vein diameter;
Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function
Keywords: اینترفرون; Immune Regulation; NS5A Inhibitor; NS3 Inhibitor; ISG; APC; allophycocyanin; ASV; asunaprevir; CXCL; chemokine C-X-C motif ligand; DAA; direct-acting antiviral; DCV; daclatasvir; EMA; ethidium monoazide; EOT; end of treatment; FBS; fetal bovine serum; FIT
ReviewFrom non-A, non-B hepatitis to hepatitis C virus cure
Keywords: اینترفرون; Hepatitis; Discovery; Direct-acting antivirals; Interferon; Ribavirin;
Pulmonary tuberculosis patients with a vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3+ regulatory T cells and IgG-secreting cells
Keywords: اینترفرون; TB; tuberculosis; Mtb; Mycobacterium tuberculosis; NO; nitric oxide; CTL; cytolytic T cell; Th; T helper; Treg; regulatory T cell; Breg; regulatory B cell; IL; interleukin; IFN; interferon; TNF; tumor necrosis factor; TGF; transforming growth factor; Ig;
The bovine model for elucidating the role of γδ T cells in controlling infectious diseases of importance to cattle and humans
Keywords: اینترفرون; AMLR; autologous mixed lymphocyte reaction; DAMP; damage-associated molecular pattern; DC; dendritic cell; IFN; interferon; IPP; isopyroprenyl phosphate; KIR; killer inhibitory receptor; mAb; monoclonal antibody; MHC; major histocompatibility complex; PAM
ReviewImmune-modulators to combat hepatitis B virus infection: From IFN-α to novel investigational immunotherapeutic strategies
Keywords: اینترفرون; Hepatitis B virus; Interferon; Cytokines/chemokines; Immune-modulators; Immunotherapy;
Toll-like receptor 2 and 6 interdependency in the erosive stage of Staphylococcus aureus induced septic arthritis mediated by IFN-γ and IL-6 - A possible involvement of IL-17 in the progression of the disease
Keywords: اینترفرون; CPCSEA; Committee for the Purpose of Control and Supervision of Experiments on Animals; CRP; C-reactive proteins; DPI; days post-infection; DST-PURSE; Department of Science and Technology-Promotion of University Research and Scientific Excellence; FLS; fi
Attenuation of vesicular stomatitis virus infection of brain using antiviral drugs and an adeno-associated virus-interferon vector
Keywords: اینترفرون; Oncolytic virus; VSV; Antiviral; Brain; Interferon; Ribavirin; AAV;
The Nuclear Factor κB pathway: A link to the immune system in the radiation response
Keywords: اینترفرون; Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP
Extrahepatic Manifestations of Hepatitis C Virus
Keywords: اینترفرون; Extrahepatic manifestations; HCV; Cryoglobulins; B-cell non-Hodgkin lymphoma; Interferon;
Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells
Keywords: اینترفرون; Chronic Infection; Hepatitis; Tolerance; ALT; alanine aminotransferase; APC; allophycocyanin; Arm; Armstrong strain; BTLA; B and T lymphocyte attenuator; CFSE; carboxyfluorescein diacetate succinimidyl ester; CTL; cytotoxic T lymphocyte; ELISA; enzyme-lin
Herbal Products and the Liver: A Review of Adverse Effects and Mechanisms
Keywords: اینترفرون; Dietary Supplement Health and Education Act; Contamination and Adulteration; Herbal Therapie; sSilymarin; ALT; alanine aminotransferase; CAM; complementary and alternative medicine; CHC; chronic hepatitis C; CYP; cytochrome P450; DILI; drug-induced liver
An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014
Keywords: اینترفرون; Erik De Clercq; Antiviral drug; Poly(I)·poly(C); Polyacrylic acid; Interferon; Reverse transcriptase; Suramin; Valaciclovir; Brivudin; Stavudine; Tenofovir disoproxil fumarate (TDF); Truvada®; Atripla®; Complera®/Eviplera®; Stribild®; FV-100; Mozobi
Original ResearchFull Report: Basic and Translational-LiverHepatitis C Virus Infection Induces Autocrine Interferon Signaling by Human Liver Endothelial Cells and Release of Exosomes, Which Inhibits Viral Replication
Keywords: اینترفرون; Innate Immunity; Immune Regulation; Cytokine; Toll-Like Receptor; GLuc; Gaussia princeps luciferase; HCV; hepatitis C virus; HSC; hepatic stellate cells; IFN; interferon; ISG; interferon-stimulated genes; JFH-1; Japanese fulminant hepatitis; LPS; lipopoly
Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine
Keywords: اینترفرون; Experimental Models of Colitis; IBD; Immune Regulation; Mesenchymal Stem Cell-Based Therapy; A-MSC; adipose-derived mesenchymal stem cell; BM; bone marrow; BM-MSC; bone marrow-derived mesenchymal stem cell; DSS; dextran sodium sulfate; GFP; green fluore
Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication
Keywords: اینترفرون; Hepatitis E virus; Eukaryotic translation initiation factor 4F complex; eIF4E-binding protein 1; Ribavirin; IFN-α; HEV; hepatitis E virus; eIF4F; eukaryotic translation initiation factor 4F; eIF4A; eukaryotic initiation translation factor 4A; eIF4G; euka
T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice
Keywords: اینترفرون; Cancer Immunotherapy; Tumor-Associated Antigens; Liver Cancer; Immune Response; E:T; effector to target cell ratio; GPC3; glypican-3; HCC; hepatocellular carcinoma; HLA; human leukocyte antigen; hTCM; human T-cell medium; IFN; interferon; IL; interleukin;
Proof of concept for a banding scheme to support risk assessments related to multi-product biologics manufacturing
Keywords: اینترفرون; Biologics; Manufacturing; Cross-contamination; Cleaning validation; Impurities; Risk assessment; ADE; acceptable daily exposure; API; active pharmaceutical ingredient; FDA; Food and Drug Administration; G-CSF; granulocyte colony stimulating factor; GM-CSF
Targeting the TGFβ pathway for cancer therapy
Keywords: اینترفرون; Angiogenesis; Fibrosis; Metastasis; Microenvironment; TGFβ inhibitors; Tumor-stroma interactions; bFGF; basic fibroblast growth factor; bi-shRNAi; bi-functional short hairpin RNAi; CAF; cancer-associated fibroblasts; CR; complete response; CTGF; connecti
The sickle cell mouse lung: proinflammatory and primed for allergic inflammation
Keywords: اینترفرون; AAD; allergic airway disease; AHR; airway hyper-responsiveness; BAL; bronchoalveolar lavage; BCA; bicinchoninic acid; BSA; bovine serum albumin; CCL; chemokine (C-C motif) ligand; CXCL; chemokine (C-X-C motif) ligand; GM-CSF; granulocyte-macrophage colony
Mast cell leukemia: An extremely rare disease
Keywords: اینترفرون; interferon; KITD816V; systemic mastocytosis; tyrosine kinase inhibitor
The STING controlled cytosolic-DNA activated innate immune pathway and microbial disease
Keywords: اینترفرون; STING; DNA sensor; Interferon; Host defense;
HCV infection during renal replacement therapy: What we have learnt in two decade?
Keywords: اینترفرون; HCV; Hemodialysis; Isolation; Transplant; Interferon
Characteristics of the cellular immune response in HIV/HCV patients with hemophilia during peginterferon/ribavirin therapy in southern China
Keywords: اینترفرون; HCV/HIV co-infection; Hemophilia; Cellular immune response; Interferon; Ribavirin
Peginterferon alfa-2a and peginterferon alfa-2b combined with ribavirin in patients with genotype 1 chronic hepatitis C: Results of a prospective single-centre study
Keywords: اینترفرون; Interferon; Pegylated interferon; Ribavirin; Treatment; HCV
Granulocyte-macrophage colony stimulating factor (GM-CSF) enhances the clinical responses to interferon-α (IFN) in newly diagnosed chronic myeloid leukemia (CML)
Keywords: اینترفرون; Chronic myeloid leukemia; Tyrosine kinase inhibitor; Cure; Discontinuation of therapy; Interferon; Growth factors
Detection of immune response activation by exogenous nucleic acids by a multiplex RT-PCR method
Keywords: اینترفرون; Immune response detection; Interferon; Multiplex RT-PCR; CpG DNA oligonucleotide; siRNAs; Toll-like receptors
Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study
Keywords: اینترفرون; MERS-CoV; Interferon; Ribavirin; Pegylated interferon
Macrophage migration inhibitory factor (MIF) -173 polymorphism is associated with clinical erythema nodosum in Löfgren's syndrome
Keywords: اینترفرون; MIF; macrophage migration inhibitory factor; EN; erythema nodosum; BHL; bilateral hilar lymphadenopathy; IPF; idiopathic pulmonary fibrosis; HLA; humon leukocyte antigen; IL; interleukin; TNF; tumor necrosis factor; IFN; interferon; SNP; single nucleotide
The roles of BDNF, S100B, and oxidative stress in interferon-induced depression and the effect of antidepressant treatment in patients with chronic viral hepatitis: A prospective study
Keywords: اینترفرون; Interferon; Depression; Neurotrophic factors; Oxidative stress;
Dose-dependent interferon-gamma release in dairy calves experimentally infected with Mycobacterium avium subspecies paratuberculosis
Keywords: اینترفرون; Paratuberculosis; Cellular immune response; Interferon; PPD Johnin; Dose; Age
Interferon-mediated ISG15 conjugation restricts dengue virus 2 replication
Keywords: اینترفرون; Dengue virus; ISG15; ISGylation; Interferon; Non-structural protein; Antiviral response;
RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication
Keywords: اینترفرون; CE; cell extract; co-IP; coimmunoprecipitation; DMEM; Dulbecco's modified Eagle's medium; dsRNA; double-stranded RNA; FBS; fetal bovine serum; FFU; focus-forming units; GAP; GTPase activating protein; GFP; green fluorescent protein; HEK; human embryo
The immunostimulatory effect of CpG oligodeoxynucleotides on peripheral blood mononuclear cells of healthy dogs and dogs with atopic dermatitis
Keywords: اینترفرون; Canine atopic dermatitis; CpG-motif; Interferon; Interleukin-10; Toll-like receptor 9
Sustained Virological Response Rates to Antiviral Therapy in Genotype 1 and 3 Chronic Hepatitis C Patients: A Study from North India
Keywords: اینترفرون; hepatitis C virus; liver disease; interferon; antivirals; sustained viral responseALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CHC, chronic hepatitis C; ETR, end of treatment response; EVR, early virological respon
TPL2 signalling: From Toll-like receptors-mediated ERK1/ERK2 activation to Cystic Fibrosis lung disease
Keywords: اینترفرون; ABIN-2; A20-binding inhibitor of NF-κB 2; CF; Cystic Fibrosis; CFTR; Cystic Fibrosis transmembrane conductance regulator; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; GSH; glutathione; IFN; Interferon; IKK; I-kappa-
STING-dependent cytosolic DNA sensing pathways
Keywords: اینترفرون; STING; cytosolic DNA; inflammation; interferon
Protection from pulmonary tissue damage associated with infection of cynomolgus macaques by highly pathogenic avian influenza virus (H5N1) by low dose natural human IFN-α administered to the buccal mucosa
Keywords: اینترفرون; HPAI-; highly pathogenic avian influenza; LPAI-; low pathogenic avian influenza; HPIVh; highly pathogenic influenza virus in humans; TLR; toll-like receptor; LDO; low dose oral; IFN; interferon; H5N1; Influenza virus; Highly pathogenic; Interferon; Oro-mu
Interleukin-28A enhances autoimmune disease in a retinal autoimmunity model
Keywords: اینترفرون; IFN; interferon; TLR; toll-like receptor; EAU; experimental autoimmune uveitis; IL; interleukin; MTB; mycobacterium tuberculosis; IRBP; interphotoreceptor retinoid-binding protein; Type III interferon; Autoimmune disease; Uveitis;
An anti-interferon activity shared by paramyxovirus C proteins: Inhibition of Toll-like receptor 7/9-dependent alpha interferon induction
Keywords: اینترفرون; IFN; interferon; PIVs; parainfluenza viruses; MeV; measles virus; NiV; Nipah virus; ORF; open reading frame; SeV; Sendai virus; ISGs; IFN-stimulated genes; ds; double stranded; PKR; protein kinase R; PAMPs; pathogen-associated molecular patterns; IRF; int
Journal of Hepatology Update: Hepatitis CSimplification of antiviral hepatitis C virus therapy to support expanded access in resource-limited settings
Keywords: اینترفرون; ARV; antiretroviral; ART; antiretroviral therapy; DAA; direct-acting antiviral agent; FDC; fixed-dose combination; HCV; hepatitis C virus; HIV; human immunodeficiency virus; IFN; interferon; PCR; polymerase chain reaction; RBV; ribavirin; WHO; World Healt