Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities
Keywords: آنتاگونیست; Cannabinoid; Ligand-receptor; Binding; Structure–activity relationships; CB1; Antagonist