Aspects of successful drug discovery and development
Keywords: توسعه دارویی; Chemotherapy; NNRTI; Protease inhibitor; HIV; Drug development
مقالات ISI توسعه دارویی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
The human reelin gene: Transcription factors (+), repressors (−) and the methylation switch (+/−) in schizophrenia
Keywords: توسعه دارویی; Schizophrenia; Methylation; Migration; GABA; Gene; Promoter; Histone deacetylase; DNA methyltransferase; Glutamate decarboxylase; Drug development; Neuron; PsychiatryAZA, azadeoxycytidine; BP, bipolar disorder; Dnmt, DNA methyltransferase; GABA, gamma-ami
Microbicides: A new frontier in HIV prevention
Keywords: توسعه دارویی; HIV-1; Microbicide; Pipeline; Drug development; Antiretroviral
Erosion of the principal investigator role in a climate of industry dominance
Keywords: توسعه دارویی; Drug development; Pharma industry
Improved early clinical development through human microdosing studies
Keywords: توسعه دارویی; Pharmaceutical Science; Drug Discovery; Techniques & Methods; Accelerator mass spectroscopy; ADME; pharmacokinetics; pharmaceutical R&D; drug development;
Molecular dissection of tropisetron, an α7 nicotinic acetylcholine receptor-selective partial agonist
Keywords: توسعه دارویی; Alzheimer's disease; Drug development; Xenopus oocytes; Voltage-clamp;
An integrated approach for inference and mechanistic modeling for advancing drug development
Keywords: توسعه دارویی; Drug development; Systems biology; Computational biology; Biomarker; Efficacy; Toxicity; Omic;
Some distinctions between flavin-containing and cytochrome P450 monooxygenases
Keywords: توسعه دارویی; Amine-, sulfide-oxygenation; Enzyme mechanism; Genetic variation; Drug development;
Clinical trial design to evaluate the effects of drugs on cardiac repolarization: Current state of the art
Keywords: توسعه دارویی; Long QT syndrome; Torsades de pointes; Arrhythmia; Drug development; Trial design; Fluoroquinolones; Ziprasidone; QT interval correction;
Quantitative risk modelling for new pharmaceutical compounds
Keywords: توسعه دارویی; Pharmaceutical Science; Drug Discovery; Development; Bioinformatics; Risk Assessment; Modelling; Drug development; Bayesian; Monte Carlo;
Use of preclinical assays to predict risk of drug-induced torsades de pointes
Keywords: توسعه دارویی; Long QT syndrome; Torsades de pointes; Electrophysiology; Arrhythmia; Arrhythmogenesis; Antiarrhythmia agents; Drug development;
Identification of the optimal third generation antifolate against P. falciparum and P. vivax
Keywords: توسعه دارویی; Antifolate; Antimalarial; Drug development; Drug design;
Targeting Angiogenesis with Vascular Endothelial Growth Factor Receptor Small-Molecule Inhibitors: Novel Agents with Potential in Lung Cancer
Keywords: توسعه دارویی; Bevacizumab; Drug development; Oral therapy; Toxicity; Tyrosine kinase inhibitors;
Novel single-round PCR and cloning of full-length envelope genes of HIV-1 may yield new insight into biomolecular antibacterial drug development
Keywords: توسعه دارویی; AIDS vaccine; Cloning; Cultures; Drug development; gp160 toxicity; Single-round gp160 PCR;
Development of cancer chemopreventive drugs based on mechanistic approaches
Keywords: توسعه دارویی; Chemoprevention; Drug development; Anticancer; Antimutagenesis; Chemoprotection;
In silico screening of chemicals for bacterial mutagenicity using electrotopological E-state indices and MDL QSAR software
Keywords: توسعه دارویی; QSAR; E-state indices; Electrotopological; Mutagenicity; In silico screening; Predictive toxicology; Drug development; Salmonella; Setubal principles;
New science-based endpoints to accelerate oncology drug development
Keywords: توسعه دارویی; Drug development; Oncology; Surrogate endpoint; Biomarker; Genomics; Proteomics; Functional imaging; Molecular imaging;
Positron Emission Tomography and Single-Photon Emission Computed Tomography in Central Nervous System Drug Development
Keywords: توسعه دارویی; Positron emission tomography/PET; SPECT; drug development; Alzheimer/Parkinson; neuroprotection; dose occupancy;
Type 2 diabetes-Therapy with dipeptidyl peptidase IV inhibitors
Keywords: توسعه دارویی; Dipeptidyl peptidase; Type 2 diabetes; GLP-1; GIP; Inhibitor; Inhibition; Drug development;
The therapeutic potential of RNA interference
Keywords: توسعه دارویی; Gene suppression; Drug development; Delivery; Safety; RNA interference
Central Nervous System Drug Development: An Integrative Biomarker Approach toward Individualized Medicine
Keywords: توسعه دارویی; CNS; genomics; drug development; translational medicine;
Modélisation numérique et simulation : nouvelles applications en pharmacologie
Keywords: توسعه دارویی; modélisation numérique; simulation; modèles thérapeutiques; innovation; développement; numerical modelling; simulation; therapeutic models; drug innovation; drug development;
The chemopreventive agent development research program in the Division of Cancer Prevention of the US National Cancer Institute: An overview
Keywords: توسعه دارویی; Cancer prevention; Chemoprevention; Carcinogenesis; Drug development
New Drugs of 2004
Keywords: توسعه دارویی; New drugs; Food and Drug Administration; drug development; pharmaceutical marketing;