Oxidative metabolism of the anti-cancer agent mitoxantrone by horseradish, lacto-and lignin peroxidase
Keywords: میلوپراکسیداز ; Cancer; Mitoxantrone drug metabolism; Novel enzymatic oxidation cascadeHRP, horseradish peroxidase; LIP, lignin peroxidase; LPO, lactoperoxidase; MPO, myeloperoxidase; HPLC, high performance liquid chromatography; RP, reversed phase; RT, retention time; A