Effect of Trichostatin A on radiation induced epithelial-mesenchymal transition in A549Â cells
Keywords: تریکوستاتین A; Radiation; EMT; Trichostatin A; TGFβ1; Docking studies;
مقالات ISI تریکوستاتین A (ترجمه نشده)
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MTA1 expression in human cancers - Clinical and pharmacological significance
Keywords: تریکوستاتین A; MTAs; metastasis associated proteins; EMT; epithelial to mesenchymal transition; NuRD; nuclear remodeling and deacetylation complex; HDAC1 or HDAC2; histone deacetylases; MBD; methylated CpG binding domain proteins; RbAb46/48; retinoblastoma associated pr
Original ArticleBCLB, methylated in hepatocellular carcinoma, is a starvation stress sensor that induces apoptosis and autophagy through the AMPK-mTOR signaling cascade
Keywords: تریکوستاتین A; BCLB; Tumor suppressor gene; Methylation; Apoptosis; Autophagy; TSGs; tumor suppressor genes; HCC; hepatocellular carcinoma; MEM; minimum essential medium; DMEM; Dulbecco's Modified Eagle's Medium; 5-Aza; 5-aza-2â²-deoxycytidine; TSA; trichostatin A; MSP
The effect of histone deacetylase inhibitor trichostatin A on porcine mesenchymal stem cell transcriptome
Keywords: تریکوستاتین A; Mesenchymal stem cells; Pig; Transcriptome; Trichostatin A;
Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride
Keywords: تریکوستاتین A; Manganese chloride; Neurotoxicity; NF-E2-related factor 2 (Nrf2); Heme oxygenase-1(HO-1); Histone acetylation; PD; Parkinson's disease; Nrf2; erythroid 2-related factor 2; HO-1; heme oxygenase 1; ROS; reactive oxygen species; GSH; reduced glutathione; PC1
The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells
Keywords: تریکوستاتین A; AG; aminoguanidine; AGE; advanced glycation end-product; Akt; protein kinase B; eNOS; endothelial NO synthase; ERK; extracellular signal-regulated protein kinase; Glo1; glyoxalase 1; HDAC; histone deacetylase; HUVECs; human umbilical vein endothelial cell
Trichostatin A (TSA) facilitates formation of partner preference in male prairie voles (Microtus ochrogaster)
Keywords: تریکوستاتین A; Partner preference; Trichostatin A; Nucleus accumbens; Oxytocin; Vasopressin; Prairie voles;
Epigenetic regulation of glucose-stimulated osteopontin (OPN) expression in diabetic kidney
Keywords: تریکوستاتین A; Diabetic kidney disease; Hyperglycemia; Histone modification; Osteopontin (OPN); Histone methyltransferase (HMT); Histone deacetylase (HDAC); DN; diabetes nephropathy; OPN; osteopontin; HDAC; histone deacetylase; HMT; histone methyltransferase; ChIP; chro
Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles
Keywords: تریکوستاتین A; Silver nanoparticles; Trichostatin A; Histone acetylation; Combinational therapy
The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase
Keywords: تریکوستاتین A; Genistein; Trichostatin A; Histone acetyltransferase; Human lung cancer cells
Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer
Keywords: تریکوستاتین A; Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM
Cigarette Smoke-Induced Hypermethylation of the GCLC Gene Is Associated With COPD
Keywords: تریکوستاتین A; antioxidants; COPD; smoking; 5-aza; 5-aza-2ʹ-deoxycytidine; BEAS-2B; human bronchial epithelial; CPG; C-phosphate-G; CS-COPD; current smoker with COPD; CSE; cigarette-smoke extract; CS-NS; current smoker with normal lung function; ES-COPD; exsmoker with
Constitutive hyperactivity of histone deacetylases enhances radioresistance in Lepidopteran Sf9 insect cells
Keywords: تریکوستاتین A; HDAC; histone deacetylase; TL; tail length; TEM; tail extent moment; PTM; post-translational modification; TSA; trichostatin A; TAU; triton-acid urea; Radioresistance; Histone deacetylase; Histone post-translational modifications; Sf9 cells; DNA damage;
Alterations of hemorheological parameters and tubulin content in erythrocytes from diabetic subjects
Keywords: تریکوستاتین A; N erythrocytes; erythrocytes from normal subjects; D erythrocytes; erythrocytes from diabetic subjects; Ac-Tub; acetylated tubulin; Sed-Tub; tubulin in sedimentable fraction; Mem-Tub; tubulin in membrane-associated fraction; Tyr-Tub; tyrosinated tubulin;
Beta-arrestin1 and 2 differently modulate metabotropic glutamate receptor 7 signaling in rat developmental sevoflurane-induced neuronal apoptosis
Keywords: تریکوستاتین A; AMN082; N,Nâ²-bis(diphenylmethyl)-1,2-ethanediamine dihydrochloride; CBP; CREB binding protein; CNS; central nervous system; CREB; cyclic adenosine 3â²,5â²-monophosphate response element binding protein; Curcumin; diferuloylmethane; DIV; days in vitro;
Trichostatin A enhances estrogen receptor-alpha repression in MCF-7 breast cancer cells under hypoxia
Keywords: تریکوستاتین A; Estrogen receptor; Hypoxia; Trichostatin A; Breast cancer;
MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation
Keywords: تریکوستاتین A; miR; microRNA; HDAC; histone deacetylase; OA; osteoarthritis; COL2A1; collagen 2; SOX9; SRY (sex-determining region Y)-box 9; RUNX2; Runt-related transcription factor 2; HAT; histone acetyltransferase; TSA; trichostatin A; Mmp13; matrix metalloproteinase
Novel histone deacetylase inhibitors derived from Magnolia officinalis significantly enhance TRAIL-induced apoptosis in non-small cell lung cancer
Keywords: تریکوستاتین A; NSCLC; non-small cell lung cancer; HDAC; histone deacetylase; HAT; histone acetyltransferase; PM; polyphenol mixture; DMSO; dimethyl sulfoxide; TV; tumor volume; SD; standard deviation; TSA; trichostatin A; Magnolol (PubChem CID: 72300); Honokiol (PubChem
Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism
Keywords: تریکوستاتین A; ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth
Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures
Keywords: تریکوستاتین A; Histone deacetylase; Serotonin; Raphe slice cultures; Trichostatin A; AMPA receptor; Ca2+/calmodulin-dependent kinase II;
Global histone modifications in Fumonisin B1 exposure in rat kidney epithelial cells
Keywords: تریکوستاتین A; FB1; Fumonisin B1; HAT; histone acetyltransferase; H3K9ac; histone H3 lysine 9 acetylation; H3K9me2; histone H3 lysine 9 dimethylation; H3K9me3; histone H3 lysine 9 trimethylation; H3K4me3; histone H3 lysine 4 trimethylation; H4K20me3; histone H4 lysine 2
Trichostatin A reduces GnRH mRNA expression with a concomitant increase in retinaldehyde dehydrogenase in GnRH-producing neurons
Keywords: تریکوستاتین A; Trichostatin A; GnRH; Kisspeptin; RALDH; Retinoic acid
Intrabody-mediated diverting of HP1β to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor
Keywords: تریکوستاتین A; HP1; heterochromatin protein 1; CD; chromodomain; CSD; chromoshadow domain; CAF-1; chromatin assembly factor 1; TIF-1β; transcriptional intermediary factor 1β; Suvar; Suppressor of variegation; INCENP; inner centromere protein; NE; nuclear envelope; LBR
Research ArticleMicroRNA-221 governs tumor suppressor HDAC6 to potentiate malignant progression of liver cancer
Keywords: تریکوستاتین A; HCC; hepatocellular carcinoma; HDAC6; histone deacetylases 6; miRNA; microRNA; 5-aza; 5-aza-2â²-deoxycytidine; TSA; trichostatin A; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; UTR; u
PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas
Keywords: تریکوستاتین A; HNSCC; Tumor suppressor gene; PHF21B; Epigenetic changes; Copy number alterations; 5-Aza-dC; 5-AZA-2â²-deoxicytidine; ENCODE; ENCyclopedia Of DNA Elements; HNSCC; head and neck squamous cell carcinoma; HPV; human papillomavirus; MS-HRM; Methylation Sensi
Structural perspective of ARHI mediated inhibition of STAT3 signaling: An insight into the inactive to active transition of ARHI and its interaction with STAT3 and importinβ
Keywords: تریکوستاتین A; ARHI; Aplasia Ras Homologue member I; STAT3; Signal Transducer and Activator of Transcription 3; NTD; N-terminal domain; CCD; Coiled-coil domain; DBD; DNA binding domain; LD; Linker domain; SH2; Src-homology-2 domain; TAD; transactivation domain; LOH; los
The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors
Keywords: تریکوستاتین A; Histone deacetylase inhibitors; Trichostatin A; Tubastatin A; 3-Hydroxypyridin-2-thione; Leishmania donovani
Trichostatin A increases the levels of plasma gelsolin and amyloid beta-protein in a transgenic mouse model of Alzheimer's disease
Keywords: تریکوستاتین A; Alzheimer's disease; Amyloid beta-protein; Gelsolin; Histone deacetylase; Transgenic mice; Trichostatin A
The expression of p21 is upregulated by forkhead box A1/2 in p53-null H1299 cells
Keywords: تریکوستاتین A; TSA; trichostatin A; FOXA1/2; forkhead box A1/2; FRE; FOXA1/2 responsible element; DBD; DNA-binding domain; Transcription factor FOXA1/2; p21; Trichostatin A; Target gene; p53-Independent pathway;
Secreted phospholipases A2 are differentially expressed and epigenetically silenced in human breast cancer cells
Keywords: تریکوستاتین A; DAC; 5-aza-2â²-deoxycytidine; HDACi; histone deacetylase inhibitor; TF; transcription factor; TSA; trichostatin A; TSS; transcription start site; DNA methylation; Epigenetics; Histone acetylation; Secreted phospholipase A2; Lipid signalling; Breast cance
The effects of selected inhibitors of histone modifying enzyme on C6 glioma cells
Keywords: تریکوستاتین A; 3DZNep; 3-deazaneplanocin; GBM; glioblastoma; HDACs; histone deacetylases; TSA; trichostatin A; VPA; valproic acid; Glioma; Epigenetics; Histone modification; Inhibitor;
Hypermethylation contributes to down-regulation of lysosomal β-hexosaminidase α subunit in prostate cancer cells
Keywords: تریکوستاتین A; Ceramide; Lysosomal glycohydrolases; Hexosaminidase A; Promoter methylation; BPH-1; hyperplasic prostate cell line; HexA; β-hexosaminidase A isoenzyme; HexB; β-hexosaminidase B isoenzyme; β-Hex; N-acetyl-β-d-hexosaminidase; MUβgala; 4 methylumbellife
Selective inhibition of class I but not class IIb histone deacetylases exerts cardiac protection from ischemia reperfusion
Keywords: تریکوستاتین A; Akt; protein kinase B; dP/dt; rate of pressure change; ERK; extracellular regulated kinase; FOXO; forkhead box protein family, subclass O; HDAC; histone deacetylase; IR; ischemia reperfusion; HEK293; human endothelial kidney cells, line 293; LV; left vent
Transcriptional repression of the Ahr gene by LHCGR signaling in preovulatory granulosa cells is controlled by chromatin accessibility
Keywords: تریکوستاتین A; Ahr; aryl hydrocarbon receptor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; TSA; trichostatin A; CHX; cycloheximide; FSK; forskolin; CHART-PCR; chromatin accessibility by real-time PCR; TSS; transcriptional start site; ActD; acinomycin D; HDAC; histone dea
Natural indoles, indole-3-carbinol and 3,3â²-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression
Keywords: تریکوستاتین A; SEB; staphylococcal enterotoxin B; I3C; indole-3-carbinol; DIM; 3,3â²-diindolylmethane; HDAC; histone deacetylase; HDAC-I; class I histone deacetylase; HDAC-II; class II histone deacetylase; TSA; trichostatin A; MG; MGCD0103; MC; MC1568; Staphylococcal e
The role of DNA methylation in regulation of the murine Lhx3 gene
Keywords: تریکوستاتین A; 5-aza-dc; 5â²-aza-2â²-deoxycytidine; αGSU; alpha glycoprotein subunit; CpG; cytosine-phosphate bond-guanine; CPHD; combined pituitary hormone deficiency; DNMT; DNA methyltransferase; FSHβ; follicle-stimulating hormone; GnRH-R; gonadotropin-releasing h
Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells
Keywords: تریکوستاتین A; ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh
Identification of Tf1 integration events in S. pombe under nonselective conditions
Keywords: تریکوستاتین A; TSA, trichostatin A; HDAC, histone deacetylase; IPCR, inverse polymerase chain reaction; G418, geneticin; neo, neomycinRetrotransposon; Integration; Heterochromatin; Fission yeast; Trichostatin A
Re-expression and epigenetic modification of maspin induced apoptosis in MCF-7 cells mediated by myocardin
Keywords: تریکوستاتین A; DNMT; DNA methyltransferase; 5-aza-dc; 5-aza-2â²-deoxycytidine; HDAC; histone deacetylase; TSA; Trichostatin A; serpin; serine protease inhibitor; DMEM; Dulbecco's modified Eagle's medium; EB; ethidium bromide; PS; phosphatidylserine; TUNEL; terminal deo
Histone deacetylases inhibitor trichostatin A modulates the extracellular release of APE1/Ref-1
Keywords: تریکوستاتین A; APE1/Ref-1; Trichostatin A; Secretion; Acetylation;
Enhanced transgene expression from chromatinized plasmid DNA in mouse liver
Keywords: تریکوستاتین A; TSA; trichostatin A; Q-PCR; quantitative PCR; RLU; relative light units; NLS; nuclear localizing signal; Exogenous DNA; Histone; Nucleosome; Intranuclear disposition; Expression efficiency;
Transcription factor Sox4 is required for PUMA-mediated apoptosis induced by histone deacetylase inhibitor, TSA
Keywords: تریکوستاتین A; TSA; trichostatin A; DBD; DNA binding domain; TAD; transactivation domain; PUMA; Transcription factor Sox4; p53-Independent apoptotic cell death; TSA; Target gene;
Identification of a histone acetyltransferase as a novel regulator of Drosophila intestinal stem cells
Keywords: تریکوستاتین A; ISC; intestinal stem cell; EB; enteroblast; EC; enterocyte; EE; enteroendocrine; HAT; histone acetyltransferase; HDAC; histone deacetylation complex; ATAC; Ada Two-A containing complex; Atac2; ATAC complex component 2; TSA; Trichostatin A; VDRC; Vienna Dr
Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation
Keywords: تریکوستاتین A; HIV-1; human immunodeficiency virus type 1; LTR; long terminal repeats; PTM; post-translational modification; SIRT1; sirtuin 1; NAD+; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; DMEM; Dulbecco's modified Eagle's mediu
MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells
Keywords: تریکوستاتین A; miRNA; microRNA; miR-214; microRNA-214; IC50; inhibit concentration 50; UTR; untranslated region; EGFP; enhanced green fluorescence protein; HA; hemagglutinin; 5-aza-CdR; 5-aza-deoxycytidine; TSA; trichostatin A; Bcl2l2; BCL2-like 2; MEK3; MAPK/ERK kinase
Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells
Keywords: تریکوستاتین A; TSA; Trichostatin A; HCC; hepatocellular carcinoma; lncRNA; long non-coding RNA; qRT-PCR; real-time quantitative reverse transcription PCR; HDAC; histone deacetylases; HDACi; histone deacetylase inhibitors; TUNEL; Terminal deoxynucleotidyltransferasedUTP
Treatment of donor cells with trichostatin A improves in vitro development and reprogramming of buffalo (Bubalus bubalis) nucleus transfer embryos
Keywords: تریکوستاتین A; Nucleus reprogramming; Trichostatin A; Embryo developmental competence; Histone acetylation;
Activation of IL-1β and TNFα genes is mediated by the establishment of permissive chromatin structures during monopoiesis
Keywords: تریکوستاتین A; Cytokines; Chromatin remodeling; Gene regulation; Hematology; Inflammation; CHART; chromatin accessibility by real-time PCR; HDAC; histone deacetylase; HPC; hematopoietic progenitor cells; TSA; trichostatin A; VD3; 1α,25-dihydroxyvitamin D3;
Green tea polyphenol epigallocatechin-3-gallate (EGCG) as adjuvant in cancer therapy
Keywords: تریکوستاتین A; Adjuvant; Cancer therapy; Epigallocatechin-3-gallate; Green tea; Side effects; 5-FU; 5-fluorouracil; ATO; arsenic trioxide; CP; cisplatin; DNR; daunorubicin; DNROL; daunorubicinol; DOX; doxorubicin; EGCG; epigallocatechin-3-gallate; HBMEC; human brain mic
Biological clues to potent DNA-damaging activities in food and flavoring
Keywords: تریکوستاتین A; γ-H2AX; phosphorylated histone protein H2AX; 5-FU; fluorouracil; CHO; Chinese hamster ovary; CMV; cytomegalovirus; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EGCG; epigallocatechin-3-gallate; FBS; fetal bovine serum; HEPES; 4