Hedgehog does not guide migrating Drosophila germ cells
Keywords: جوجه‌تیغی، خارپشت; Primordial germ cells; Drosophila; Hedgehog; HMGCoA reductase; tout velu;
مقالات ISI جوجه‌تیغی، خارپشت (ترجمه نشده)
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Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis
Keywords: جوجه‌تیغی، خارپشت; FGF; fibroblast growth factor; TGF; transforming growth factor; Hh; hedgehog; VEGF; vascular endothelial growth factor; PDGF; platelet derived growth factor; Shh; sonic hedgehog; GAG; glycosaminoglycan; HS; heparan sulfate; HS6ST; heparan sulfate 6-O sulf
Regulation of Hh signal transduction as Drosophila eye differentiation progresses
Keywords: جوجه‌تیغی، خارپشت; Drosophila eye; Signal transduction; Morphogenetic furrow; Hedgehog; Cubitus Interruptus; EGF receptor;
Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas
Keywords: جوجه‌تیغی، خارپشت; HH, hedgehog; NSCLC, non-small cell lung cancer; FOXM1, Forkhead Box M1; SHH, sonic hedgehog; PTCH1, patched1; SMO, Smoothened; SCLC, small cell lung cancer; SuFu, suppressor of fusedGLI; FOXM1; Hedgehog; NSCLC; PTCH1; SHH; SMO
Synthesis and biological evaluation of SANT-2 and analogues as inhibitors of the hedgehog signaling pathway
Keywords: جوجه‌تیغی، خارپشت; SANT-2; Cyclopamine; Hedgehog; Medaka; Cyclopia
Wingless and Hedgehog signaling pathways regulate orthodenticle and eyes absent during ocelli development in Drosophila
Keywords: جوجه‌تیغی، خارپشت; Ocelliless; Orthodenticle; Hedgehog; Wingless; Eyes absent; Cubitus interruptus; Ocelli development; Drosophila
Hedgehog signaling patterns mesoderm in the sea urchin
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Patched; Smoothened; Morphogenesis; Endoderm; Mesoderm; Signal transduction;
Liver Cell-Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells
Keywords: جوجه‌تیغی، خارپشت; BDL; bile duct ligation; Hh; Hedgehog; Ihh; Indian Hedgehog; iNOS; inducible nitric oxide synthase; K19; keratin 19; MF-HSC; myofibroblastic hepatic stellate cells; MPs; microparticles; PDGF; platelet-derived growth factor; SEC; sinusoidal endothelial cel
Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development
Keywords: جوجه‌تیغی، خارپشت; Gli2; Hedgehog; Neural tube;
Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib
Keywords: جوجه‌تیغی، خارپشت; Doxorubicin; Sunitinib; Anti-angiogenesis; P-glycoprotein; Drug transport; Hypoxia; High-dose; Glycolysis; ATP levels; Energy metabolism; Kinases; Tumor stroma; Hedgehog; HIF-1; STAT3; Quantitative resistance assays
Tow (Target of Wingless), a novel repressor of the Hedgehog pathway in Drosophila
Keywords: جوجه‌تیغی، خارپشت; Patched; Smoothened; Tow; Hedgehog; Signalling; Development; Wing disc; Drosophila; Lipophorin
Therapeutic options for triple-negative breast cancers with defective homologous recombination
Keywords: جوجه‌تیغی، خارپشت; ABC; ATP-binding cassette; APC; Adenomatous, polyposis coli; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3-related; BER; base-excision repair; BRCA1; Breast cancer susceptibility gene 1; BRCA2; Breast cancer susceptibility gene 2; CGH; Comparative
Development of zebrafish swimbladder: The requirement of Hedgehog signaling in specification and organization of the three tissue layers
Keywords: جوجه‌تیغی، خارپشت; Zebrafish; Swimbladder; Hedgehog; fgf10; Enhancer trap; Lung
Cardiovascular Anatomy, Physiology, and Disease of Rodents and Small Exotic Mammals
Keywords: جوجه‌تیغی، خارپشت; Cardiovascular; Rodent; Marsupial; Hedgehog; Skunk; Disease;
Depletion of the Colonic Epithelial Precursor Cell Compartment Upon Conditional Activation of the Hedgehog Pathway
Keywords: جوجه‌تیغی، خارپشت; Bmp; bone morphogenetic protein; Hh; Hedgehog; Ihh; Indian hedgehog; PCR; polymerase chain reaction; Ptch; Patched; Shh; Sonic hedgehog; Smo; Smoothened;
Cadmium and cellular signaling cascades: To be or not to be?
Keywords: جوجه‌تیغی، خارپشت; Apoptosis; ER stress; Calmodulin; PI 3-kinase; ERK; p38-MAPK; JNK; Phosphodiesterase; Ca2+-sensing receptor; Wnt/β-catenin; Hedgehog
Autonomous Hedgehog signalling is undetectable in PC-3 prostate cancer cells
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; PC-3 cells; Autocrine; Prostate cancer; Gli; Luciferase; Cyclopamine
Expression patterns of Shh, Ptc2, Raldh3, Pitx2, Isl1, Lim3 and Pax6 in the developing chick hypophyseal placode and Rathke’s pouch
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Patched; Raldh3; Pitx2; Lim3; Isl1; Pax6; Hypophyseal placode; Rathke’s pouch; Pituitary; Chick
Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; GLI; Zizyphus cambodiana; Colubrinic acid
The decoupling of Smoothened from Gαi proteins has little effect on Gli3 protein processing and Hedgehog-regulated chick neural tube patterning
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Smoothened; G protein; Gli3; Neural tube
Recent progress in the study of Hedgehog signaling
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; processing; signal transduction
Comparing the survival of osteocalcin and mtDNA in archaeological bone from four European sites
Keywords: جوجه‌تیغی، خارپشت; Osteocalcin; Protein mass spectrometry; ZooMS; Biomolecular archaeology; African elephant; Hedgehog; Pig-tailed macaque; Bushbaby; Opossum; Tree shrew; Lesser hedgehog; Lerna; Zauschwitz; Asine; Portalón; Collagen; Ancient DNA
Specification of vertebrate slow-twitch muscle fiber fate by the transcriptional regulator Blimp1
Keywords: جوجه‌تیغی، خارپشت; Myotome; Myoblast; Zebrafish; Slow-twitch muscle; Fast-twitch muscle; Hedgehog; Blimp1; Slow myosin heavy chain; Prox1; Fast myosin light chain
Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum
Keywords: جوجه‌تیغی، خارپشت; Cerebellum; Purkinje neuron; Eurydendroid neuron; Hedgehog; Wnt; Zebrafish; Dorsoventral; olig2
Unexpected activities of Smad7 in Xenopus mesodermal and neural induction
Keywords: جوجه‌تیغی، خارپشت; Xenopus; Chick; Chicken; Neural induction; FGF; BMP; Wnt; Hedgehog; Retinoic acid; Nodal; Smad6; Smad7; TGFβ;
Branchless and Hedgehog operate in a positive feedback loop to regulate the initiation of neuroblast division in the Drosophila larval brain
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; FGF; Branchless; Neural stem cell; Drosophila; Proliferation; Neuroblast;
An Integrated Approach Identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated Genes in Developing Cerebellum and Medulloblastoma
Keywords: جوجه‌تیغی، خارپشت; EGL; external granule layer; EMSA; electrophoretic mobility shift assay; GCP; granule cell precursor; GST; glutathione-S-transferase; HH; Hedgehog; MB; medulloblastoma; Ptc; Patched; QPCR; quantitative polymerase chain reaction; Shh; Sonic Hedgehog;
All along the watchtower: Is the cilium a tumor suppressor organelle?
Keywords: جوجه‌تیغی، خارپشت; Cilia; Wnt; Hedgehog; von Hippel–Lindau; Polycystic kidney disease; Renal cell carcinoma
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice
Keywords: جوجه‌تیغی، خارپشت; PACAP; Hedgehog; Medulloblastoma; Pathched; Cerebellum; Protein kinase A; Pituitary adenylyl cyclase activating peptide; PKA; cAMP; Brain tumor
Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye
Keywords: جوجه‌تیغی، خارپشت; Zebrafish; Optic vesicle; Coloboma; Hedgehog; Patched1
Expression profiling identifies novel Hh/Gli-regulated genes in developing zebrafish embryos
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Detour (dtr); Slow muscle omitted (smu); Interrenal gland; Pronephros; Nervous system; Microarray; Transcriptional profiling
Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye
Keywords: جوجه‌تیغی، خارپشت; Choroid; Hedgehog; Patched; Endothelium; Sclera; Differentiation; Condensation; Mesenchyme; Neural crest; Retina
Proliferative and cell fate effects of Hedgehog signaling in the vertebrate retina
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Proliferation; Progenitor; Retinal ganglion cell; Cell fate; Retina; Development; Muller glia; Differentiation; Gli; Hes1; Patched; Neurogenesis
Accumulation of Hedgehog-Responsive Progenitors Parallels Alcoholic Liver Disease Severity in Mice and Humans
Keywords: جوجه‌تیغی، خارپشت; CK; cytokeratin; DF; discriminant function; Frp; Frizzled related peptide; Gli2; Glioblastoma; Hh; Hedgehog; HF; high fat; HNF6; hepatocyte nuclear factor-6; Ptc; patch; PT; portal tract;
Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Optic nerve; Proliferation; Glia; Ccnd1; Cdc25b; Mouse
Hedgehog and Dpp signaling induce cadherin Cad86C expression in the morphogenetic furrow during Drosophila eye development
Keywords: جوجه‌تیغی، خارپشت; Drosophila; Eye imaginal disc; Morphogenetic furrow; Cell shape; Hedgehog; Dpp; Cadherin; Cad86C
The Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolution
Keywords: جوجه‌تیغی، خارپشت; Anthozoa; Cnidaria; Ectoderm; Endoderm; Evolution; Genomics; Gli; Hedgehog; Induction; Nematostella vectensis; Patched; Pattern formation; Signal transduction
Hedgehog Signaling Is Required for Effective Regeneration of Exocrine Pancreas
Keywords: جوجه‌تیغی، خارپشت; Hh; Hedgehog;
Hedgehog signaling pathway in neural development and disease
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Numb; RENKCTD11; Development; Brain; Cancer
Hedgehog is involved in prostate basal cell hyperplasia formation and its progressing towards tumorigenesis
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Basal cell hyperplasia; Prostate cancer; Tumorigenesis; Basal stem cells; Cancer stem cells
Activin B mediated induction of Pdx1 in human embryonic stem cell derived embryoid bodies
Keywords: جوجه‌تیغی، خارپشت; Activin; Embryonic stem cells; Hedgehog; Pancreas development
The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells
Keywords: جوجه‌تیغی، خارپشت; Cyclopamine; Hedgehog; Insulin-like growth factor; Akt; p27
GSK3β positively regulates Hedgehog signaling through Sufu in mammalian cells
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; GSK3β; Sufu; Gli; Phosphorylation
Survivin and hedgehog protein expression in serrated colorectal polyps: an immunohistochemical study
Keywords: جوجه‌تیغی، خارپشت; Survivin; Hedgehog; Serrated; Polyp; Colorectum
Tumour suppressors in liver carcinogenesis
Keywords: جوجه‌تیغی، خارپشت; APC; adenomatous polyposis coli; HBx; Hepatitis B virus protein x; Hh; Hedgehog; HIT; histidine triad; mTOR; mammalian target of rapamycin; PI3K; phosphatidyl-inositide-3OH-kinase; PIP3; phosphatidyl-inositide-3, 4, 5-P3; S6K; S6 kinase;
New paradigms in signal transduction
Keywords: جوجه‌تیغی، خارپشت; Nucleating receptor; Signaling by proteolysis; Hedgehog; Wnt; Histidine kinase; Reactive oxygen species
The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning
Keywords: جوجه‌تیغی، خارپشت; Gli3 activator; Gli3 repressor; Hedgehog; Limb patterning
Analysis of talpid3 and wild-type chicken embryos reveals roles for Hedgehog signalling in development of the limb bud vasculature
Keywords: جوجه‌تیغی، خارپشت; talpid3; Hedgehog; Limb; Vascular development; VEGF; Angiopoietin
Cross regulation of intercellular gap junction communication and paracrine signaling pathways during organogenesis in Drosophila
Keywords: جوجه‌تیغی، خارپشت; Drosophila; Gap junctions; Morphogens; Hedgehog; Wingless; Innexin2; Delta; Foregut; Organogenesis
PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Growth plate; PTHrP; Gli; Organ culture; Proliferation; Differentiation