The cholinergic system and hippocampal plasticity
Keywords: پلاستیسیته سیناپسی; Acetylcholine; Hippocampus; Slice; Synaptic plasticity; LTP; Muscarinic; Nicotinic
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Effects of birth asphyxia on neonatal hippocampal structure and function in the spiny mouse
Keywords: پلاستیسیته سیناپسی; Birth asphyxia; Hippocampus; Sex; Spiny mouse; Synaptic plasticity; Long-term potentiation
Ultrastructural relationship between the AMPA-GluR2 receptor subunit and the mu-opioid receptor in the mouse central nucleus of the amygdala
Keywords: پلاستیسیته سیناپسی; Addiction; Glutamate; Opioids; Synaptic plasticity;
Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment
Keywords: پلاستیسیته سیناپسی; Adult neurogenesis; Seizures; Synaptic plasticity; Electrophysiology; Spines; Rat
Plasticidad sináptica funcional y disfuncional en la corteza prefrontal: papel en los trastornos psiquiátricos
Keywords: پلاستیسیته سیناپسی; Funciones cognitivas; Dopamina; Glutamato; Corteza prefrontal; Esquizofrenia; Plasticidad sináptica; Cognitive functions; Dopamine; Glutamate; Prefrontal cortex; Schizophrenia; Synaptic plasticity;
Humanized Foxp2 specifically affects cortico-basal ganglia circuits
Keywords: پلاستیسیته سیناپسی; FOXP2; dendrite length; synaptic plasticity; evolution; pleiotropy; ANOVA; analysis of variance; LTD; long-term depression; PBS; phosphate buffered saline; TBST; tris buffered saline Tween 20;
N-methyl-d-aspartate receptor subunit composition in the rat trigeminal principal nucleus remains constant during postnatal development and following neonatal denervation
Keywords: پلاستیسیته سیناپسی; trigeminal brainstem; infraorbital nerve; glutamate receptors; NR2A subunit; NR2B subunit; synaptic plasticity; ACSF; artificial cerebrospinal fluid; ANCOVA; analysis of covariance; ANOVA; analysis of variance; d-APV; d(-)-2-amino-5-phosphono-pentanoic ac
Hippocampal phenotypes in kalirin-deficient mice
Keywords: پلاستیسیته سیناپسی; GEF; Synaptic plasticity; Dendrite; Dendritic spine; Rac1; Knockout; Fear conditioning;
The expression mechanism of the residual LTP in the CA1 region of BDNF k.o. mice is insensitive to NO synthase inhibition
Keywords: پلاستیسیته سیناپسی; Nitric oxide; TrkB; Neurotrophins; Synaptic plasticity; Retrograde messenger
Prenatal stress and neonatal handling induce sex-specific changes in dendritic complexity and dendritic spine density in hippocampal subregions of prepubertal rats
Keywords: پلاستیسیته سیناپسی; dendritic spines; dendritic development; limbic; synaptic plasticity; depressionANOVA, analysis of variance; C, Control; CA1, CA3 subregions of the hippocampal formation; DG, dentate gyrus; H, neonatal handling; PNS, prenatal stress
Ovarian hormones, aging and stress on hippocampal synaptic plasticity
Keywords: پلاستیسیته سیناپسی; Hippocampus; Synaptic plasticity; Rat; Estrogen; Progesterone; Aging; Stress
Neuroinflammation and the plasticity-related immediate-early gene Arc
Keywords: پلاستیسیته سیناپسی; Synaptic plasticity; Learning and memory; Immediate-early gene; Arc; Neuroinflammation; Innate immune system; Cytokines; Neuronal networks; Fractalkine; Hippocampal circuits
Lateral organization of the postsynaptic density
Keywords: پلاستیسیته سیناپسی; Synaptic transmission; Synaptic plasticity; AMPA receptors; PSD-95; Super-resolution imaging; EM tomography; Computational modeling
Hippocampal inputs mediate theta-related plasticity in anterior thalamus
Keywords: پلاستیسیته سیناپسی; anterior thalamic nuclei; fornix; mammillothalamic tract; synaptic plasticity; theta oscillation; LTPANOVA, analysis of variance; ATN, anterior thalamic nuclei; FP, field potential; Fx, fornix; HFS, high-frequency stimulation; LFP, local field potential;
An N-methyl-d-aspartate-receptor dependent, late-phase long-term depression in middle-aged mice identifies no GluN2-subunit bias
Keywords: پلاستیسیته سیناپسی; long term depression; synaptic plasticity; hippocampal CA1-region; in vitroACSF, artificial cerebrospinal fluid; CPP, (R)-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid; d-AP5, d(−)-2-amino-5-phospho-pentanoic acid; EPSCs, excitatory postsynaptic cur
Short-term, moderate exercise is capable of inducing structural, bdnf-independent hippocampal plasticity
Keywords: پلاستیسیته سیناپسی; Physical exercise; Synaptic plasticity; Structural plasticity; Neurogenesis; Doublecortin; BDNF; Corticosterone;
Regulation and function of immediate-early genes in the brain: Beyond neuronal activity markers
Keywords: پلاستیسیته سیناپسی; Immediate-early gene; Arc; Synaptic activity; Long-term memory; Synaptic plasticity; CREB; Gene mapping; Hippocampus
PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders
Keywords: پلاستیسیته سیناپسی; IGF-1; Brain homeostasis; Neurodevelopmental disorders; PEGylated IGF; Synaptic plasticity
The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in
Keywords: پلاستیسیته سیناپسی; Phosphodiesterase; PDE9; Neurite outgrowth; LTP; Synaptic plasticity; Rodent cognition
Ethanol modulation of synaptic plasticity
Keywords: پلاستیسیته سیناپسی; Ethanol; Withdrawal; Synaptic plasticity; Review
Neuropathic pain- and glial derived neurotrophic factor-associated regulation of cadherins in spinal circuits of the dorsal horn
Keywords: پلاستیسیته سیناپسی; N-cadherin; E-cadherin; Spinal nerve ligation; Rat; Synaptic plasticity; Nerve regeneration;
Phosphorylation of spinal N-methyl-d-aspartate receptor NR1 subunits by extracellular signal-regulated kinase in dorsal horn neurons and microglia contributes to diabetes-induced painful neuropathy
Keywords: پلاستیسیته سیناپسی; N-methyl-d-aspartate receptor; Diabetes; Neuropathic pain; Signal transduction; Synaptic plasticity;
Pulsed magnetic field exposure induces lasting changes in neural network dynamics
Keywords: پلاستیسیته سیناپسی; Spiking neurons network; Synaptic plasticity; Low-frequency electromagnetic fields; Time–frequency analysis
Carvedilol as a potential novel agent for the treatment of Alzheimer's disease
Keywords: پلاستیسیته سیناپسی; Oligomeric Aβ; Cognitive function; Spatial memory; Basal neuronal transmission; Dendritic spine; Synaptic plasticity; Bioavailability;
NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity
Keywords: پلاستیسیته سیناپسی; Leptin; Synaptic transmission; NMDA receptor; Synaptic plasticity; PI 3-kinase; MAPK
Research ReportDifferential roles of ERK, JNK and p38 MAPK in pain-related spatial and temporal enhancement of synaptic responses in the hippocampal formation of rats: Multi-electrode array recordings
Keywords: پلاستیسیته سیناپسی; Persistent pain; Hippocampal formation; Synaptic plasticity; Multi-electrode-array; Mitogen-activated protein kinases;
Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion
Keywords: پلاستیسیته سیناپسی; Schizophrenia; 22q11.2 deletion; Hippocampus; Interneuron; c-Fos; Disinhibition; Synaptic plasticity; CA1; CA3
Role of ubiquitin–proteasome-mediated proteolysis in nervous system disease
Keywords: پلاستیسیته سیناپسی; Neurodegenerative disease; Mental disorders; Synaptic plasticity; Therapeutic targets; Alzheimer’s; Parkinson's
Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways
Keywords: پلاستیسیته سیناپسی; Antidepressant; Glutamate receptors; Synaptic plasticity; NMDA; Phosphorylation; Signaling pathway;
Persistent increase of d-aspartate in d-aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay
Keywords: پلاستیسیته سیناپسی; d-Aspartate; NMDA receptors; Synaptic plasticity; Reference memory; Hippocampus; Brain aging;
Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression
Keywords: پلاستیسیته سیناپسی; Chemokine; Synaptic plasticity; Short-term potentiation; Long-term potentiation; Post-tetanic potentiation; Electrophysiology; Hippocampal slice; Western blot; Field potential
Increased d-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice
Keywords: پلاستیسیته سیناپسی; d-Aspartate; NMDA receptors; Synaptic plasticity; Reference memory; Hippocampus; Brain aging
Dynamic regulation of midbrain dopamine neuron activity: intrinsic, synaptic, and plasticity mechanisms
Keywords: پلاستیسیته سیناپسی; burst; pause; firing pattern; reward prediction error; disinhibition; synaptic plasticity; Ach; acetylcholine; DA; dopamine; Ih; hyperpolarization-activated cationic conductance; IP3; inositol 1,4,5-trisphosphate; LDTg; laterodorsal tegmental nucleus; mGl
Spontaneous firing and evoked pauses in the tonically active cholinergic interneurons of the striatum
Keywords: پلاستیسیته سیناپسی; TAN; autonomous discharge; acetylcholine dopamine balance; synaptic plasticity; neuromodulation; reward signalingACh, acetylcholine; AHP, afterhyperpolarization; BK, big conductance calcium and voltage activated potassium; ChAT, choline acetyltransferase;
Temporal modulation of hippocampal excitatory transmission by corticosteroids and stress
Keywords: پلاستیسیته سیناپسی; Corticosterone; Corticosteroid receptors; Excitatory synapse; Glutamate release; Glutamatergic receptors; Hippocampus; Stress; Synaptic plasticity; Trafficking
Endocannabinoid-mediated synaptic plasticity and addiction-related behavior
Keywords: پلاستیسیته سیناپسی; Synaptic plasticity; Endocannabinoid; Addiction; Relapse; Stress; Affective disorder
mTOR inhibitor rapamycin suppresses striatal post-ischemic LTP
Keywords: پلاستیسیته سیناپسی; Stroke; Oxygen and glucose deprivation; Synaptic plasticity; Striatum
Estrogen-mediated effects on cognition and synaptic plasticity: What do estrogen receptor knockout models tell us?
Keywords: پلاستیسیته سیناپسی; Estrogen; Cognition; Synaptic plasticity; Estrogen receptor (ERα and ERβ) ER knockout model; CNS
MDMA (“ecstasy”) impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats
Keywords: پلاستیسیته سیناپسی; MDMA; Synaptic plasticity; Visuo-spatial learning; Hippocampus
Alterations in both acetylcholinesterase activity and synaptic scaffolding protein localization in the nervous system of Drosophila presenilin mutants
Keywords: پلاستیسیته سیناپسی; Acetylcholinesterase; Alzheimer's disease; Synaptic plasticity; Discs large; Synaptic terminals
Differential roles of GRIP1a and GRIP1b in AMPA receptor trafficking
Keywords: پلاستیسیته سیناپسی; Synaptic plasticity; LTD; Palmitoylation; Glutamate; PDZ domain;
Genomic and non-genomic actions of estrogen on synaptic plasticity in SH-SY5Y cells
Keywords: پلاستیسیته سیناپسی; Arc; Estrogen receptor; Synaptic plasticity; Genomic estrogenic action; Non-genomic estrogenic action;
Repeated restraint-induced modulation of long-term potentiation in the dentate gyrus of the mouse
Keywords: پلاستیسیته سیناپسی; Repeated stress; Hippocampus; Synaptic plasticity; Glucocorticoid receptor; Mineralocorticoid receptor;
Acoustic tone or medial geniculate stimulation cue training in the rat is associated with neocortical neuroplasticity and reduced akinesia under haloperidol challenge
Keywords: پلاستیسیته سیناپسی; Sensory cueing; Parkinson's disease; Synaptic plasticity; Golgi; Haloperidol; Movement; Evoked response
Long-term dietary restriction modulates the level of presynaptic proteins in the cortex and hippocampus of the aging rat
Keywords: پلاستیسیته سیناپسی; GAP-43; Synaptophysin; α-Synuclein; Dietary restriction; Aging; Rat cortex; Hippocampus; Synaptic plasticity
A sensitizing d-amphetamine dose regimen induces long-lasting spinophilin and VGLUT1 protein upregulation in the rat diencephalon
Keywords: پلاستیسیته سیناپسی; Synaptic plasticity; Radioimmunocytochemistry; Psychostimulants; Behavioral sensitization;
Convergent actions of orexin/hypocretin and CRF on dopamine neurons: Emerging players in addiction
Keywords: پلاستیسیته سیناپسی; Orexin/hypocretin; CRF; VTA; synaptic plasticity; AMPAR; NMDAR; LTP
Hippocampal region-specific regulation of NF-κB may contribute to learning-associated synaptic reorganisation
Keywords: پلاستیسیته سیناپسی; Learning; Transcription factor; Synaptic plasticity; Neuronal structure
Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction
Keywords: پلاستیسیته سیناپسی; TNF-α; Neuroinflammation; Alzheimer's; Parkinson's; Synaptic plasticity; Ionic homeostasis
Protein acetylation in synaptic plasticity and memory
Keywords: پلاستیسیته سیناپسی; Histone acetylation; Deacetylase; Long-term potentiation; Memory; Synaptic plasticity