The effect of intravitreal cholinergic drugs on motor control
Keywords: استیل کولین; Acetylcholine; Retina; Movement; Atropine; Carbachol; Cogentin; Circadian;
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miR-51 regulates GABAergic synapses by targeting Rab GEF GLO-4 and lysosomal trafficking-related GLO/AP-3 pathway in Caenorhabditis elegans
Keywords: استیل کولین; GABA; γ-aminobutyric acid; PTZ; pentylenetetrazole; SNB-1; Synaptobrevin 1; GEF; guaninenucleotide exchange factor; SVs; synaptic vesicles; ACh; acetylcholine; NMJs; neuromuscular junctions; miRNAs; microRNAs; GluR; glutamate receptor; nAChR; neuronal ac
Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases
Keywords: استیل کولین; Muscarinic; Receptor; Acetylcholine; M1; M4; Orthosteric; Allosteric; Preclinical; Clinical; Cognition; Alzheimer; Psychosis; Neurodegenerative; Neurology; Neuropsychiatric;
Inhibition of basal and amphetamine-stimulated extracellular signal-regulated kinase (ERK) phosphorylation in the rat forebrain by muscarinic acetylcholine M4 receptors
Keywords: استیل کولین; Caudate putamen; Nucleus accumbens; Prefrontal cortex; Acetylcholine; Dopamine; Tropicamide; Telenzepine; Amphetamine;
Polymorphic variation in the SLC5A7 gene influences infant autonomic reactivity and self-regulation: A neurobiological model for ANS stress responsivity and infant temperament
Keywords: استیل کولین; Respiratory sinus arrhythmia; SLC5A7; Acetylcholine; Temperament; Self-regulation; Health disparities;
Nicotinic acetylcholine receptor (nAChR) mediated dopamine release in larval Drosophila melanogaster
Keywords: استیل کولین; Drosophila; nAChR; Acetylcholine; Nicotine; Neonicotinoid; Dopamine;
Functional characterization of α7 nicotinic acetylcholine and NMDA receptor signaling in SH-SY5Y neuroblastoma cells in an ERK phosphorylation assay
Keywords: استیل کولین; Acetylcholine; Glutamate; α7 nicotinic receptors; NMDA receptors; Amyloid-β1-42; Extracellular-signal regulated kinase phosphorylation;
Aβ dimers induce behavioral and neurochemical deficits of relevance to early Alzheimer's disease
Keywords: استیل کولین; Alzheimer's disease; Amyloid β dimer; tgDimer mouse; Memory; 5-HT; Acetylcholine;
Bioactivities of decoctions from Plectranthus species related to their traditional use on the treatment of digestive problems and alcohol intoxication
Keywords: استیل کولین; ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; ANOVA; analysis of variance; BHT; butylated hydroxytoluene; DMEM; Dubelcco's modified Eagle medium; DMSO; dimethyl sulfoxide
Optimizing conventional DMARD therapy for Sjögren's syndrome
Keywords: استیل کولین; 6-MP; 6-mercaptopurine; 6-T-GTP; 6-thioguanine triphosphate; ABT; abatacept; Ach; acetylcholine; ALAT; alanine amino transferase; AZA; azathioprine; BAFF; B cell activating factor; Bcl-6; B cell lymphoma 6; bDMARDs; biological disease modifying antirheuma
Vitamin D partially reverses the increase in p-NF-κB/p65 immunocontent and interleukin-6 levels, but not in acetylcholinesterase activity in hippocampus of adult female ovariectomized rats
Keywords: استیل کولین; Ach; acetylcholine; AChE; acetylcholinesterase; ANOVA; analysis of variance; ChAT; choline acetyltransferase; CNS; central nervous system; HRT; hormone replacement therapy; IL-1β; interleukin-1β; IL-6; interleukin 6; NF-kB; nuclear factor-kappa B; OVX;
Quercetin treatment regulates the Na+,K+-ATPase activity, peripheral cholinergic enzymes, and oxidative stress in a rat model of demyelination
Keywords: استیل کولین; ACh; acetylcholine; AChE; acetylcholinesterase; AcSCh; acetylthiocholine; BuChE; butyrylcholinesterase; CAT; catalase; CNS; central nervous system; DTNB; 5,5â²-dithio-bis-2-nitrobenzoic acid; EB; ethidium bromide; Hb; hemoglobin; MDA; malondialdehyde; MS
Ethnopharmacology, phytochemistry, and pharmacology of Chinese Salvia species: A review
Keywords: استیل کولین; ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AST; aspartate transaminase; CAT; catalase; CCL4; carbon tetrachloride; CK; casein kinase; DMN; dimethylnitrosamine; DPPH; 2,2-diphenyl-1-picrylhydrazyl; GSH; glutathione; HPRI; hepa
Sodium butyrate attenuates diabetes-induced aortic endothelial dysfunction via P300-mediated transcriptional activation of Nrf2
Keywords: استیل کولین; 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; ACh; acetylcholine; AHR; aryl hydrocarbon receptor; ChIP; chromatin immunoprecipitation; c-NRF2; cytosolic NRF2; Ctrl; control; DM; diabetes mellitus; EC; endothelial cell; HDAC; histone deacetylase; HG; hig
Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia
Keywords: استیل کولین; Congenital myasthenic syndromes; Acetylcholine; Vesicular acetylcholine transporter skeletal muscle; Cholinergic transmission; Motor function;
Galantamine attenuates N,N-dimethyl hydrazine induced neoplastic colon damage by inhibiting acetylcholinesterase and bimodal regulation of nicotinic cholinergic neurotransmission
Keywords: استیل کولین; Acetylcholine; Cholinergic anti-inflammatory pathway; Colon cancer; Galantamine; Inflammation; Vagus nerve;
Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms
Keywords: استیل کولین; AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; TCAs; tricyclic antidepressants; α-BTx; α-bungarotoxin; MLA; methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activati
Vasodilator and hypotensive effects of pure compounds and hydroalcoholic extract of Xenophyllum poposum (Phil) V.A Funk (Compositae) on rats
Keywords: استیل کولین; Xenophyllum poposum; Hypotension; Vasodilation; Pure compounds; Rat aorta; ACh; acetylcholine; Ang II; angiotensin II; DMSO; dimethyl sulfoxide; DBP; diastolic blood pressure; HAE X. poposum or Xp; hydroalcoholic extract of Xeneophyllum poposum; HPLC-ESI-
Gating of long-term potentiation (LTP) in the thalamocortical auditory system of rats by serotonergic (5-HT) receptors
Keywords: استیل کولین; 5-HT; 5-hydroxytryptamine; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; 5-HTR; 5- hydroxytryptamine receptor; A1; primary auditory cortex; ACh; acetylcholine; fPSP; field postsynaptic potential; i.p.; intraperitoneal; LTD; long-term
Aloysia citrodora Paláu (Lemon verbena): A review of phytochemistry and pharmacology
Keywords: استیل کولین; AC; Aloysia citrodora; Min; minimum; EO; Essential oil; MIC; minimum inhibitory concentration; AEC; aqueous extract of cedrón; Ach; acetylcholine; TBARS; thiobarbituric acid-reactive substances; CL; chemiluminescence; MDA; malondialdehyde; FRAP; ferric r
The 5-HT3 receptor antagonist ondansetron potentiates the effects of the acetylcholinesterase inhibitor donepezil on neuronal network oscillations in the rat dorsal hippocampus
Keywords: استیل کولین; 5-HT3 receptor; Acetylcholinesterase inhibitor; Ondansetron; Donepezil; Neuronal oscillations; Alzheimer's disease; 5-HT; 5-hydroxytryptamine (serotonin); 5-HT3receptor; 5-hydroxytryptamine 3 receptor; 5-HT6receptor; 5-5-hydroxytryptamine 6 receptor; Aβ;
Substituent effect of N-benzylated gramine derivatives that prevent the PP2A inhibition and dissipate the neuronal Ca2+ overload, as a multitarget strategy for the treatment of Alzheimer's disease
Keywords: استیل کولین; ACh; acetylcholine; AD; Alzheimer's disease; Aβ; amyloid β peptide; [Ca2+]c; cytosolic Ca2+; CALHM1; Ca2+ homeostasis modulator-1 channel; FBS; fetal bovine serum; Mem; memantine; NCLX; mitochondrial Na±/Ca2+ exchanger; NFT; neurofibrillary tangles;
AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks
Keywords: استیل کولین; Adverse Outcome Pathways (AOPs); Risk assessment; Data mining; Database; Data integration; Association networks; ACHE; acetylcholinesterase; ACh; acetylcholine; AO; Adverse Outcome; AOP; Adverse Outcome Pathway; AOP-DB; Adverse Outcome Pathway Data Base;
Postnatal Changes in K+/Clâ Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy
Keywords: استیل کولین; ACh; acetylcholine; ADNFLE; autosomal dominant nocturnal frontal lobe epilepsy; AP; action potential; AP5; d(â)-2-amino-5-phosphono-pentanoic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; CTRL; control transgenic mice not expressing β2-V287L; EGABA
Muscarinic receptor subtype distribution in the central nervous system and relevance to aging and Alzheimer's disease
Keywords: استیل کولین; Muscarinic; Acetylcholine; Cholinergic; CNS; GPCR;
Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor
Keywords: استیل کولین; ACh; acetylcholine; mAChR; muscarinic acetylcholine receptor; GPCR; G protein-coupled receptor; AD; Alzheimer's disease; PAM; positive allosteric modulator; NAM; negative allosteric modulator; TM; transmembrane domain; ECL; extracellular loop; CHO; Chin
Substance P and neurotensin in the limbic system: Their roles in reinforcement and memory consolidation
Keywords: استیل کولین; ACh; acetylcholine; BLA; basolateral amygdala; BNST; bed nucleus of stria terminalis; CeA; central nucleus of amygdala; CPU; caudate-putamen; CPP; conditioned place preference; DA; dopamine; dPAG; dorsal part of the periaqueductal gray matter; EPM; elevat
A new outlook on cholinergic interneurons in Parkinson's disease and L-DOPA-induced dyskinesia
Keywords: استیل کولین; Cholinergic interneurons; Acetylcholine; Dopamine; Striatum; Parkinson's disease; L-DOPA; Dyskinesia;
Effect fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data?
Keywords: استیل کولین; 2C-B; 2,5-Dimethoxy-4-bromophenethylamine; 4-FA; 4-Fluoroamphetamine; 4-MEC; 4-Methylethcathinone; 4-MMC; 4-Methylmethcathinone, a.k.a. mephedrone; 5-APB; 5-(2-Aminopropyl)benzofuran; 6-APB; 6-(2-Aminopropyl)benzofuran; 5-HT; Serotonin; 25B-NBOMe; 4-Bromo
The histology, physiology, neurochemistry and circuitry of the substantia gelatinosa Rolandi (lamina II) in mammalian spinal cord
Keywords: استیل کولین; [Ca2+]i; intracellular Ca2+ concentration; 5-HT; serotonin; Ach; acetylcholine; AMP; adenosine monophosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptor; BDNF; brain-derived neurotrophic factor; CCK; cholecystokinin;
Topographical projections from the nucleus basalis magnocellularis (Meynert) to the frontal cortex: A voltage-sensitive dye imaging study in rats
Keywords: استیل کولین; Basal forebrain; Acetylcholine; Cognitive function; Motor function; DBS;
Desipramine increases cardiac parasympathetic activity via α2-adrenergic mechanism in rats
Keywords: استیل کولین; Acetylcholine; Cardiac microdialysis; Desipramine; Rats; Yohimbine;
Acetylcholine released from T cells regulates intracellular Ca2 +, IL-2 secretion and T cell proliferation through nicotinic acetylcholine receptor
Keywords: استیل کولین; Acetylcholine; Nicotinic acetylcholine receptor; Spontaneous [Ca2Â +]i increase; Interleukin-2; T cells;
Acetylcholine-induced ex vivo ATP release from the human nasal mucosa
Keywords: استیل کولین; Ach; acetylcholine; M3AchR; M3 acetylcholine receptor; PLC; phospholipase C; PIP2; phosphatidylinositol bisphosphate; DAG; diacylglycerol; IP3; inositol triphosphate; IP3R; inositol triphosphate receptor; P2X7; purinergic P2X7 receptor; Human nasal mucosa
Surface modified nano-lipid drug conjugates of positive allosteric modulators of M1 muscarinic acetylcholine receptor for the treatment of Alzheimer's disease
Keywords: استیل کولین; US-FDA; United States Food and Drugs Administration; AD; Alzheimer's disease; ACh; acetylcholine; PAM; positive allosteric modulator; mAChR; muscarinic acetylcholine receptor; AChE; acetylcholine esterase; LDC; lipid drug conjugate; NP; nanoparticle; GP
M1 muscarinic receptors are necessary for retrieval of remote context fear memory
Keywords: استیل کولین; Fear conditioning; Inhibitory avoidance; Memory retrieval; Remote memory; M1 receptor; Acetylcholine;
Intracoronary acetylcholine application as a possible probe inducing J waves in patients with early repolarization syndrome
Keywords: استیل کولین; Acetylcholine; Early repolarization syndrome; J waves; Vasospastic angina;
Leukotriene receptor antagonist attenuated airway inflammation and hyperresponsiveness in a double-stranded RNA-induced asthma exacerbation model
Keywords: استیل کولین; Asthma; Cysteinyl leukotrienes; Double-stranded RNA; Leukotriene receptor antagonist; Virus; Ach; acetylcholine; AHR; airway hyperresponsiveness; ASM; airway smooth muscle; BAL; bronchoalveolar lavage; BALF; bronchoalveolar lavage fluid; CCL; Chemokine (C
Muscarinic cholinergic receptor antagonists in the VTA and RMTg have opposite effects on morphine-induced locomotion in mice
Keywords: استیل کولین; Laterodorsal tegmental nucleus; Pedunculopontine tegmental nucleus; Opiates; Dopamine; Acetylcholine;
Acetylcholinesterase inhibitory assessment of isolated constituents from Salsola grandis Freitag, Vural & Adıgüzel and molecular modeling studies on N-acetyltryptophan
Keywords: استیل کولین; ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; MPLC; medium pressure liquid chromatography; NMR; , nuclear magnetic resonance; SCC; silica gel column chromatography; TLC; thin layer chromatography; Salsola grandis; Chenopodiace
Hemicholinium-3 sensitive choline transport in human T lymphocytes: Evidence for use as a proxy for brain choline transporter (CHT) capacity
Keywords: استیل کولین; Choline transporter; T lymphocytes; Synaptosomes; Acetylcholine; Genetic CHT variants;
Aberrant alpha and gamma oscillations ex vivo after single application of the NMDA receptor antagonist MK-801
Keywords: استیل کولین; Schizophrenia; NMDA receptor antagonist; Gamma rhythm; Alpha oscillations; Q factor; Acetylcholine;
Moderate, Short-Term, Local Hyperglycemia Attenuates Forearm Endothelium-Dependent Vasodilation After Transient Ischemia-Reperfusion in Human Volunteers
Keywords: استیل کولین; hyperglycemia; ischemia-reperfusion injury; forearm blood flow; endothelium; vascular reactivity; acetylcholine;
A silk peptide fraction restores cognitive function in AF64A-induced Alzheimer disease model rats by increasing expression of choline acetyltransferase gene
Keywords: استیل کولین; ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer disease; BF-7; brain factor-7; ChAT; choline acetyltransferase; CNS; central nervous system; CSF; cerebrospinal fluid; F3.ChAT; neural stem cell encoding ChAT gene; GFAP; glial fibrillary acidi
The effect of glyphosate-based herbicide Roundup and its co-formulant, POEA, on the motoric activity of rat intestine - In vitro study
Keywords: استیل کولین; ACh; acetylcholine; POEA; polyethyloxylated tallow amine; Isop; isoproterenol; MK-HS; modifies Krebs-Henseleit solution; PPP; plant protection product; Roundup; POEA; Glyphosate; Motoric activity; Jejunum strips; Interaction;
Cholinergic neurons in the dorsomedial hypothalamus regulate food intake
Keywords: استیل کولین; Acetylcholine; Muscarinic; Nicotinic; Obesity; POMC; Hypothalamus;
Retigabine diminishes the effects of acetylcholine, adrenaline and adrenergic agonists on the spontaneous activity of guinea pig smooth muscle strips in vitro
Keywords: استیل کولین; KCNQ (Kv7) channels; voltage-gated potassium channels; KS; modified Krebs solution; ACh; acetylcholine; AUC; area under the curve; BT; baseline tone; BT + Amean; relative change in spontaneous muscle contraction; KCNQ; Acetylcholine; Adrenaline; α-adre
Research articleSynergistic effect of tanshinone IIA and mesenchymal stem cells on preventing learning and memory deficits via anti-apoptosis, attenuating tau phosphorylation and enhancing the activity of central cholinergic system in vascular dementia
Keywords: استیل کولین; VaD; vascular dementia; MSCs; mesenchymal stem cells; 4-VO; four-vessel occlusion; TSA; tanshinone II A; AD; Alzheimer's disease; MWM; morris water maze; GSK 3β; glycogen synthase kinase 3β; ACh; acetylcholine; ChAT; choline acetyltransferase; AChE; a
Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease
Keywords: استیل کولین; AD; Alzheimer's disease; AChEIs; acetylcholinesterase inhibitors; NMDA; N-methyl-d-aspartate; Aβ; β-amyloid; Ï; tau protein; ACh; acetylcholine; MTDLs; multi-target-directed ligands; MAO-B; monoamine oxidase B; MAO-A; monoamine oxidase A; BuChE; buty
Lobeline attenuates ethanol abstinence-induced depression-like behavior in mice
Keywords: استیل کولین; Nicotinic receptor; Alcohol; Major depression; Lobeline; Hippocampus; Mice; ACh; acetylcholine; BDNF; brain-derived neurotrophic factor; BrdU; 5-bromo 2â²-deoxyuridine; FST; forced swim test; nAChR; nicotinic acetylcholine receptor; PFC; prefrontal corte