دانلود مقالات ISI درباره آژانس دارویی اروپا + ترجمه فارسی

PBT assessment and prioritization of contaminants of emerging concern: Pharmaceuticals

Keywords: آژانس دارویی اروپا; AD; Applicability Domain; API; Active Pharmaceutical Ingredient; B; Bioaccumulative; BCF; BioConcentration Factor; bor AD; borderline Applicability Domain; CAS; Chemicals Abstracts Service; CEC; Contaminants of Emerging Concern; EMEA; European Medicines A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleLactic acidosis in patients with hepatitis C virus cirrhosis and combined ribavirin/sofosbuvir treatment

Keywords: آژانس دارویی اروپا; ALT; alanine transaminase; AST; aspartate transaminase; APRI; aspartate aminotransferase to platelet ratio index; CP-Score; Child-Pugh-Score, DCV, daclatasvir; EMA; European Medicines Agency; ETR; end of treatment response; eGFR; estimated glomerular filt

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

CommentaryBiosimilars: A consideration of the regulations in the United States and European union

Keywords: آژانس دارویی اروپا; Biosimilar; Pharmacovigilance; Extrapolation; Interchangeability; Regulation; US Food and Drug Administration; (FDA); European Medicines Agency; (EMA); Europe; (EU); United States; (US); International Nonproprietary Name; (INN); World Health Organization;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Is sunitinib a Narrow Therapeutic Index Drug? - A systematic review and in vitro toxicology-analysis of Sunitinib vs. Imatinib in cells from different tissues

Keywords: آژانس دارویی اروپا; Apoptosis; Drug safety; Imatinib; Narrow Therapeutic Index Drug (NTID); Receptor tyrosine kinase (RTK); Sunitinib; Toxicity; Tyrosine kinase inhibitor (TKI); Cell viability; ALL; acute lymphoblastic leukemia; AUC; area under the curve; b.i.d.; twice daily

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies

Keywords: آژانس دارویی اروپا; 4-HPAA; 4-hydroxyphenyl acetic acid; ACN; acetonitrile; BSA; bovine serum albumin; Cal; calibrator; CCl; cell layer capacitance; CNS; central nervous system; CV%; coefficient of variation; CPT-cAMP; 8-(4-chlorophenylthio)-adenosine-3′,5′-cyclic monoph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media

Keywords: آژانس دارویی اروپا; precipitation; supersaturation; Caco-2 cells; dissolution; formulation; gastrointestinal; in vitro/in vivo correlations; intestinal absorption; permeability; cyclodextrins; AUC; area under the curve; AUDC; area under the dissolved drug amount-time curve

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

New agents for the treatment of drug-resistant Mycobacterium tuberculosis

Keywords: آژانس دارویی اروپا; Mtb; Mycobacterium tuberculosis; TB; Tuberculosis; MDR-TB; Multidrug-resistant tuberculosis; RIF; Rifampicin; INH; Isoniazid; PZA; Pyrazinamide; ETH; Ethambutol; WHO; World Health Organization; CYP; Cytochrome P450; ADME; Absorption, distribution, metabol

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

A meta-analysis of efficacy and safety of aripiprazole in adult and pediatric bipolar disorder in randomized controlled trials and observational studies

Keywords: آژانس دارویی اروپا; FDA; Food and Drug Administration; EMA; European Medicines Agency; 5HT1A-5HT2A; 5- hydroxytryptamine receptors; D2; Dopamine Receptor D2; Safety; Sedation; Akathisia; Weight gain; Extrapyramidal symptoms; Gastroenteric symptoms; Hyperprolactinemia; Lithiu

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Antitumor dendritic cell-based vaccines: lessons from 20 years of clinical trials and future perspectives

Keywords: آژانس دارویی اروپا; APCs; antigen-presenting cells; cDCs; classical DCs; CTLs; cytotoxic T cells; CTLA-4; cytotoxic T-lymphocyte-associated antigen 4; DC; dendritic cell; Dex; dendritic cell-derived exosomes; EMA; European Medicines Agency; FDA; Food and Drug Administratio

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

PLGA-based nanoparticles: A new paradigm in biomedical applications

Keywords: آژانس دارویی اروپا; Biodegradable; Poly(lactic-co-glycolic acid); Nanoparticles; Targeting; Sustained release; DCC; N,N-Dicyclohexylcarbodiimide; DDS; Drug delivery system; DNA; Deoxyribose nucleic acid; EDC; 1-ethyl-3-(3-dimethylaminopropyl carbodiimide); EGFR; Epidermal gr

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Unravelling exemestane: From biology to clinical prospects

Keywords: آژانس دارویی اروپا; AI(s); aromatase inhibitor (s); AKT; protein kinase B; AREG; amphiregulin; BMD; bone mineral density; CYP; cytochrome P450; DHEAS; dehydroepiandrosterone sulfate; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMA; European Medicine

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Cocaine and crack cocaine abuse by pregnant or lactating mothers and analysis of its biomarkers in meconium and breast milk by LC-MS-A review

Keywords: آژانس دارویی اروپا; Cocaine/crack; Biomarkers; Breast milk; Meconium; LC-MS; ACN; Acetonitrile; AEC; Anhydroecgonine; AEME; Anhydroecgonine methyl ester; ANVISA; National Health Surveillance Agency; BZE; Benzoylecgonine; CET; Cocaethylene; COC; Cocaine; CNO; Cocaine-N-oxid

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Mefloquine at the crossroads? Implications for malaria chemoprophylaxis in Europe

Keywords: آژانس دارویی اروپا; Mefloquine; European Medicines Agency; Adverse events; Malaria prophylaxis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

ALK-FISH borderline cases in non-small cell lung cancer: Implications for diagnostics and clinical decision making

Keywords: آژانس دارویی اروپا; ADC; adenocarcinoma; ADSC; adenosquamous carcinoma; ALK; anaplastic lymphoma kinase; BL; borderline; CNG; copy number gain; EMA; European Medicines Agency; FDA; Food and Drug Administration; FISH; fluorescence in-situ hybridization; FS; fused signals; FN;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The adsorption of allergoids and 3-O-desacyl-4′-monophosphoryl lipid A (MPL®) to microcrystalline tyrosine (MCT) in formulations for use in allergy immunotherapy

Keywords: آژانس دارویی اروپا; MPL®; monophosphoryl lipid A; MCT; microcrystalline tyrosine; WHO; World Health Organisation; EMA; European Medicines Agency; MATA; modified allergen tyrosine adsorbed; C-H⋯π; carbon hydrogen delocalised aromatic electron interaction; IgE; immunoglo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

High-performance liquid chromatography-tandem mass spectrometry method for the determination of perampanel, a novel α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist in human plasma

Keywords: آژانس دارویی اروپا; AED; anti-epileptic drugs; AMPA; α-amin-3-hydroxyl-5methyl-4isoxazolepropionic acid; AUC; area under the plasma concentration-time curve; AUC0-inf; AUC extrapolated to infinity; AUC0-last; AUC to the last time points; AUMC; area under the first mom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Les médicaments orphelins : des opportunités méconnues pour les développeurs en Europe

Keywords: آژانس دارویی اروپا; Orphan Drug Act; règlement 141/2000/CE; règlement d'éxécution 847/2000; Communication de la Commission (2003/C 178/02); médicaments orphelins; exclusivité commerciale de 10 ans; médicaments similaires; bénéfice notable; supériorité clinique;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

17β-Estradiol and natural progesterone for menopausal hormone therapy: REPLENISH phase 3 study design of a combination capsule and evidence review

Keywords: آژانس دارویی اروپا; Bioidentical hormones; 17β-Estradiol; Menopause; Progesterone; Vasomotor symptoms; CBHT; compounded bioidentical hormone therapy; CEE; conjugated equine estrogens; EMA; European Medicines Agency; FDA; Food and Drug Administration; HDL-C; high-density lip

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

RTS,S: Toward a first landmark on the Malaria Vaccine Technology Roadmap

Keywords: آژانس دارویی اروپا; CHMP; Committee for Medicinal Products for Human Use; CSP; circumsporozoite protein; EMA; European Medicines Agency; GFATM; Global Fund to Fight Aids, Tuberculosis and Malaria; HBsAg; hepatitis B virus surface antigen; ITT; intention-to-treat; JTEG; Joint

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Immunogenicity and safety of an AS03-adjuvanted H5N1 pandemic influenza vaccine in Korean adults: A phase IV, randomized, open-label, controlled study

Keywords: آژانس دارویی اروپا; AS03; H5N1 vaccine; Pandemic influenza; Korean adults; AEs; adverse events; CBER; US Center for Biologics Evaluation and Research; CHMP; Committee for Medicinal Products for Human Use; CI; confidence interval; EMA; European Medicines Agency; FDA; US Food

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Idiopathic pulmonary fibrosis: Recent advances on pharmacological therapy

Keywords: آژانس دارویی اروپا; Clinical trials; Idiopathic pulmonary fibrosis; Nintedanib; Pirfenidone; Therapy; Treatment; AE; acute exacerbation; AEC; alveolar epithelial cell; ANCOVA; analysis of covariance; DLCO; diffusing capacity of the lung for carbon monoxide; DPLD; diffuse par

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Regulatory aspects of clinical xenotransplantation

Keywords: آژانس دارویی اروپا; Cell-based medicinal products; European Medicines Agency; Food and Drug Administration; Medical devices; Porcine endogenous retrovirus; Regulatory framework

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The European I-MOVE Multicentre 2013-2014 Case-Control Study. Homogeneous moderate influenza vaccine effectiveness against A(H1N1)pdm09 and heterogenous results by country against A(H3N2)

Keywords: آژانس دارویی اروپا; Influenza vaccine; Vaccine effectiveness; Influenza vaccine effectiveness; Test-negative design; Multicentre study; ARI; acute respiratory infection; Df; degrees of freedom; EMA; European Medicines Agency; EU; European Union; HI; hemagglutination inhibiti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Optimal design of trials to demonstrate the utility of genomically-guided therapy: Putting Precision Cancer Medicine to the test

Keywords: آژانس دارویی اروپا; Clinical trial design; Precision Cancer Medicine; Targeted therapy; CSC; Cancer stem cell; COSMIC; Catalogue of Somatic Mutations in Cancer; CTC; Circulating tumor cell; ctDNA; Circulating tumor DNA; CRC; Colorectal cancer; DCR; Disease control rate; EMA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Role of patient-reported outcomes and other efficacy endpoints in the drug approval process in Europe (2008–2012)

Keywords: آژانس دارویی اروپا; European Medicines Agency; European Public Assessment Report; Patient reported outcomes; Health related quality of health

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Pigment Epithelial Detachment Followed by Retinal Cystoid Degeneration Leads to Vision Loss in Treatment of Neovascular Age-Related Macular Degeneration

Keywords: آژانس دارویی اروپا; AMD; age-related macular degeneration; CATT; Comparison of AMD Treatment Trials; CNV; choroidal neovascularization; CRT; central retinal thickness; EMA; European Medicines Agency; ETDRS; Early Treatment Diabetic Retinopathy Study; FDA; Food and Drug Admin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Praziquantel efficacy against Brachylaima sp. metacercariae (Trematoda: Brachylaimidae) parasitizing the edible landsnail Cornu aspersum and its HPLC-MS/MS residue determination

Keywords: آژانس دارویی اروپا; Brachylaima; Cornu aspersum; Praziquantel; Efficacy; HPLC-MS/MS; Brachylaimiasis; ADI; acceptable daily intake; CI; confidence intervals; CV; coefficient of variation; CVMP; Committee for Veterinary Medicinal Products; EMA; European Medicines Agency; HPLC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Les bases pharmacologiques de la thérapeutique. Analyse pharmacologique du résumé des caractéristiques d'un produit ( le « RCP ») pour le thérapeute

Keywords: آژانس دارویی اروپا; résumé des caractéristiques d'un produit; RCP; pharmacologie; thérapeutique; summary of product caracteristics; SPC; pharmacology; therapeutics; AMM; autorisation de mise sur le marché; ANSM; Agence Nationale de Sécurité du Médicament et des pro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications

Keywords: آژانس دارویی اروپا; ADC; antibody drug conjugate; ALL; acute lymphoid leukemia; AML; acute myeloid leukemia; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMA; European Medicines Agency; EPR; enhanced permeability and retention effect; FDA; US Food an

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4-butanediol (1,4-BD; BDO): A literature review with a focus on UK fatalities related to non-medical use

Keywords: آژانس دارویی اروپا; 1,4-BD; 1,4-butanediol; AM; ante mortem; AMCD; Advisory Council on the Misuse of Drugs; BNF; British National Formulary; BZP; benzylpiperazine; Carboxy-THC; 11-nor-9-carboxy-delta-9-THC; CNS; central nervous system; CPP; 1-(3-chlorophenyl)piperazine hydro

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Adaptation of the quality by design concept in early pharmaceutical development of an intranasal nanosized formulation

Keywords: آژانس دارویی اروپا; API; active pharmaceutical ingredient; Cmax; maximum plasma concentration; CQA; critical quality attribute; CPP; critical process parameter; EMA; European Medicines Agency; FDA; Food and Drug Administration; HA; sodium hyaluronate; ICH; International Conf

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

Analytical and statistical comparability of generic enoxaparins from the US market with the originator product

Keywords: آژانس دارویی اروپا; AT; antithrombin; ATIII; antithrombin III; BSA; bovine serum albumin; CNBr; cyanogen bromide; CTA; cetyltrimethylammonium; CZE; capillary zone electrophoresis; EMA; European Medicines Agency; FDA; US Food and Drug Administration; Gal; galactose; GlcA; glu

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

14th Annual Meeting of the Safety Pharmacology Society: Threading through peripheral and central nervous system presentations

Keywords: آژانس دارویی اروپا; Aβ; Aβ-amyloid protein; AANEM; American Academy of Neuromuscular and Electrodiagnostic Medicine; AAN; American Academy of Neurology; AD; Alzheimer's Disease; API; Alzheimer's Prevention Initiative-APOE4; ADF; Abuse Deterrent Formulations; ADNI; Alzheime

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2015 سفارش ترجمه

First evaluation of a multi-capillary electrophoresis CDT assay on Helena Biosciences' V8 analyser

Keywords: آژانس دارویی اروپا; CDT; carbohydrate-deficient transferrin; Tf; transferrin; HPLC; high performance liquid chromatography; CE; capillary electrophoresis; QCs; quality control samples; EQUALIS; external quality assessment for clinical laboratory investigations; SD; standard

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

PerspectiveFlorbetapir (18F) for brain amyloid positron emission tomography: Highlights on the European marketing approval

Keywords: آژانس دارویی اروپا; Florbetapir (18F); Positron emission tomography; β-Amyloid; Brain; European Medicines Agency; Marketing approval;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Toxicologie de la reproduction : intérêt et interprétation

Keywords: آژانس دارویی اروپا; médicament; grossesse; fertilité; développement embryonnaire et fœtal; règlementation; drugs; pregnancy; fertility; embryofetal development; regulatory guidance; off-label prescribing; DES; diéthylsilbestrol; EMA; European medicines agency; FDA; Foo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Le Centre de référence sur les agents tératogènes (CRAT) : une structure pionnière

Keywords: آژانس دارویی اروپا; médicament; grossesse; allaitement; malformation; nouveau-né; drug; pregnancy; lactation; birth defect; newborn; ABM; Agence de biomédecine; Afssaps; Agence française de sécurité sanitaire des produits de santé; AMM; autorisation de mise sur le mar

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Development and application to clinical practice of a validated HPLC method for the analysis of β-glucocerebrosidase in Gaucher disease

Keywords: آژانس دارویی اروپا; GD; Gaucher disease; GBA; β-glucocerebrosidase; GlcCer; glucocerebroside; FACS; fluorescence-activated cell sorter; PNP-Glc; 4-nitrophenyl-β-d-glucopyranoside; PNP; p-nitrophenol; ERT; enzyme replacement therapy; IMG; imiglucerase; EMA; European Medicin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

High throughput identification and quantification of 16 antipsychotics and 8 major metabolites in serum using ultra-high performance liquid chromatography-tandem mass spectrometry

Keywords: آژانس دارویی اروپا; 7OH-NDA-QUE; 7-hydroxy-N-desalkyl-quetiapine; 7OH-QUE; 7-hydroxy-quetiapine; AMI; amisulpride; AP; antipsychotics; AGNP; Arbeidsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie; ARI; aripiprazole; ASE; asenapine; BRO; bromperidol; CLO; c

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Chemical analysis of estragole in fennel based teas and associated safety assessment using the Margin of Exposure (MOE) approach

Keywords: آژانس دارویی اروپا; ADI; acceptable daily intake; BMDL10; lower confidence limit of the benchmark dose resulting in a 10% extra cancer incidence; EFSA; European Food Safety Authority; EMA; European Medicines Agency; ESCO; EFSA Scientific Cooperation; HPLC; high performance l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Isotrétinoïne et grossesse : bilan français de 25 années de suivi

Keywords: آژانس دارویی اروپا; isotrétinoïne; grossesse; isotretinoïn; pregnancy; Afssaps; Agence française de sécurité sanitaire des produits de santé; AMM; autorisation de mise sur le marché; ANSM; Agence nationale de sécurité du médicament et des produits de santé; CRAT;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities

Keywords: آژانس دارویی اروپا; 5-HT; 5-hydroxy tryptamine (serotonin); 5-HTT; serotonin transporter; AAP; atypical antipsychotics; ACH; acetylcholine; ADR; adverse drug reaction; AP; antipsychotic; CDSR; cochrane database of systematic reviews; CTZ; chemotrigger zone; DAT; dopamine tra

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

Keywords: آژانس دارویی اروپا; PPAR gamma; Nuclear receptor; Natural product; Nutrition; Diabetes; 9-(S)-HODE; (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid; AF-2; activation function-2; CAP; c-Cbl-associated protein; Cdk5; cyclin-dependent kinase 5; DCM; dichloromethane; DIO; diet

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Nanomedicines in the future of pediatric therapy

Keywords: آژانس دارویی اروپا; ACTs; artemisinin combined therapies; ALN; alendronate; ANMAT; Administración Nacional de Medicamentos, Alimentos y Tecnología Médica; ARV; antiretrovirals; AS; antisense; AUC; area-under-the-curve; BMS; burning mouth syndrome; CD; cytosine deaminase;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه

Advancing toxicology in RiskMAPP: Setting ADEs based on the subsequent drug substance

Keywords: آژانس دارویی اروپا; ADE; acceptable daily exposure; BW; body weight; DSA; first drug substance used in processing drug equipment; DSB; subsequent drug substance used in processing drug equipment; EMA; European Medicines Agency; ICH; International Conference on Harmonisation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

A public-private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee

Keywords: آژانس دارویی اروپا; ADRs; adverse drug reactions; CDER; Center for Drug Evaluation and Research; cTn; cardiac troponin; CV; cardiovascular; EMA; European Medicines Agency; EWG; Expert Working Group; ECG; electrocardiogram; HESI; Health and Environmental Sciences Institute; h

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleSustained virologic response rates with telaprevir by response after 4 weeks of lead-in therapy in patients with prior treatment failure

Keywords: آژانس دارویی اروپا; HCV; hepatitis C virus; SVR; sustained virologic response; DAA; direct-acting antiviral; FDA; Food and Drug Administration; EMA; European Medicines Agency; SD; standard deviation; BMI; body mass index; Direct-acting antiviral; Hepatitis C virus; Response

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line

Keywords: آژانس دارویی اروپا; 1:2dil; 1:2 dilution at toi; A/PR/8; A/Puerto Rico/8/34; CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6; EMA; European medicines agency; FDA; Food and Drug Administration; FITC; fluorescein isothiocyanate; GMEM; Glasgow minimum essenti

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Thujone and thujone-containing herbal medicinal and botanical products: Toxicological assessment

Keywords: آژانس دارویی اروپا; Thujone; Risk assessment; Toxicity; Metabolism; Pharmacokinetics; ADI; acceptable daily intake; BMDL; benchmark dose (lower confidence limit); CNS; central nerve system; CYP; cytochrome P450; EMA; European Medicines Agency; GABAA; gamma-aminobutyric acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Application of in vitro biopharmaceutical methods in development of immediate release oral dosage forms intended for paediatric patients

Keywords: آژانس دارویی اروپا; BCS; Biopharmaceutics classification system; EMA; European Medicines Agency; FaSSIF; Fasted state simulated intestinal fluid; FDA; (United States) Food and Drug Administration; FeSSIF; Fed state simulated intestinal fluid; GI; Gastrointestinal; IVIVR; In

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه