Deletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam
Keywords: گابا; Dlk2; NOTCH; Anxiety; Stress; GABA; HPA axis;
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Involvement of GABAA and GABAB receptors in afterdischarge generation in rat hippocampal slices
Keywords: گابا; Disorders of the nervous system; Epilepsy: basic mechanisms; Epilepsy; Afterdischarge; Ictal activity; GABA; Disinhibition; Hippocampal slice;
Chemical synthesis of 7α-hydroxypregnenolone, a neuroactive steroid that stimulates locomotor activity
Keywords: گابا; GABA; gamma-aminobutyric acid; NMR; nuclear magnetic resonance; CYP; cytochrome P450; TLC; thin-layer chromatography; Steroid chemistry; Neuroactive steroids; Chemical synthesis; C-H functionalization; Cytochrome P450 enzymology;
Electrophysiological properties of neurons and synapses in the lateral habenular complex (LHb)
Keywords: گابا; AMPA-R; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; 5-HT; 5-hydroxytryptamine (serotonin); EP; entopeduncular nucleus (rodent equivalent of the internal globus pallidus in higher mammals); GABA; gamma-aminobutyric acid; GABA-A receptor
Assessment of anoxia tolerance and photoperiod dependence of GABAergic polarity in the pond snail Lymnaea stagnalis
Keywords: گابا; APf; action potential frequency; ANOVA; Analysis of Variance; CCC; cation-chloride co-transporter; [Clâ]; Chloride Concentration; GABA; gamma-aminobutyric acid; [GABA]; GABA concentration; KCC2; K+-Clâ cotransporter isoform 2; LD; light:dark; MΩ; meg
Archival ReportThe Unpredictive Brain Under Threat: A Neurocomputational Account of Anxious Hypervigilance
Keywords: گابا; Anxiety; Dynamic causal modeling; GABA; Hypervigilance; Magnetoencephalography; Mismatch negativity;
Preclinical evidence of the anxiolytic and sedative-like activities of Tagetes erecta L. reinforces its ethnobotanical approach
Keywords: گابا; Diazepam (PubChem CID: 3016); Flumazenil (PubChem CID: 3373); Sodium pentobarbital (PubChem CID: 23676152); WAY100635 maleate salt (PubChem CID: 11957721); Anxiolytic; Ethnobotany; Flavonoids; GABA; Pharmacology; Sedative; Serotonin; Tagetes erecta; Tradi
Chronic GABAergic blockade in the spinal cord in vivo induces motor alterations and neurodegeneration
Keywords: گابا; AMPA receptor; Excitotoxicity; GABA; Glycine; Motor neuron; Spinal cord;
The binding orientation of epibatidine at α7 nACh receptors
Keywords: گابا; Cys-loop; Ion channel; Radioligand; Epibatidine; Agonist; α7 nACh; Nicotinic; Receptor; AChBP; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HT
The GadX regulon affects virulence gene expression and adhesion of porcine enteropathogenic Escherichia coli in vitro
Keywords: گابا; EPEC; GadX; GABA; Adhesion; Bacteria-host interaction; Diarrhea;
Comprehensive association analysis of 27 genes from the GABAergic system in Japanese individuals affected with schizophrenia
Keywords: گابا; GABA; Gamma-aminobutyric acid; DSM-IV; The Diagnostic and Statistical Manual of Mental Disorders-IV; SNP; Single Nucleotide Polymorphism; LD; Linkage Disequilibrium; GABRA1; Gephyrin; Schizophrenia; SNP; Association study;
Enriched environment and Mash1 transfection affect neural stem cell differentiation after transplantation into the adult somatosensory cortex
Keywords: گابا; ACSF; artificial cerebrospinal fluid; bFGF; basic fibroblast growth factor; bHLH; basic helix-loop-helix; DMEM; Dulbecco's modified Eagle medium; EE; enriched environment; EPSC; excitatory postsynaptic currents; GABA; gamma-aminobutyric acid; GAD; glutami
Targeted screening of succinic semialdehyde dehydrogenase deficiency (SSADHD) employing an enzymatic assay for γ-hydroxybutyric acid (GHB) in biofluids
Keywords: گابا; CV; coefficient of variation; GABA; gamma-aminobutyric acid; GC-FID; gas chromatography-flame ionization detector; GC-MS; gas chromatography-mass spectrometry; GHB; gamma-hydroxybutyrate (also γ-hydroxybutyric acid); GHBDH; GHB-dehydrogenase; IDM; is
Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer
Keywords: گابا; Antinociception; Bone cancer pain; Extracellular regulated kinase; Opioid; Rewarding effect; GABA; γ-aminobutyric acid; CPP; conditioned place preference; FBC; femur bone cancer; NAC; nucleus accumbens; p-ERK; phosphorylated-extracellular regulated kinas
Maternal care and affective behavior in female offspring: Implication of the neurosteroid/GABAergic system
Keywords: گابا; Anhedonia; Allopregnanolone; Maternal; Female; GABA; Hippocampus;
Uridine attenuates morphine-induced conditioned place preference and regulates glutamate/GABA levels in mPFC of mice
Keywords: گابا; Uridine; Morphine; Conditioned place preference; Medial prefrontal cortex; GABA; Glutamate;
Optimization of germination time and temperature to maximize the content of bioactive compounds and the antioxidant activity of purple corn (Zea mays L.) by response surface methodology
Keywords: گابا; Purple corn; Germination; GABA; Phenolic compounds; Antioxidant activity;
Research articleValproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy
Keywords: گابا; PD; Parkinson's disease; DAergic; dopaminergic; SNpc; substantia nigra pars compacta; VPA; valproic acid; HDAC; histone deacetylase; GABA; gamma aminobutyric acid; MPTP; 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine; GDNF; glial cell line-derived neurot
Review articleGlutamate dysregulation and glutamatergic therapeutics for PTSD: Evidence from human studies
Keywords: گابا; Posttraumatic stress disorder (PTSD); Glutamate; Glutamine; GABA; NMDA; Neurobiology; Neurotransmission; Novel therapeutics; Treatment; Ketamine; d-Cycloserine;
Region-specific increases in FosB/ÎFosB immunoreactivity in the rat brain in response to chronic sleep restriction
Keywords: گابا; ABC; avidin-biotin-horseradish peroxidase complex; ANOVA; analysis of variance; CSR; chronic sleep restriction; EC; exercise control; GABA; γ-aminobutyric acid; HC; home cage; ir; immunoreactive; LW; locked wheel; MCH; melanin-concentrating hormone; NREM
Targeted transcranial theta-burst stimulation alters fronto-insular network and prefrontal GABA
Keywords: گابا; iTBS; TMS; Effective connectivity; Insula; GABA; Neuromodulation;
Divergent influences of anterior cingulate cortex GABA concentrations on the emotion circuitry
Keywords: گابا; Emotion processing; GABA; fMRI; MRS; IAPS; dACC; Amygdala; Hippocampus;
Targeting interhemispheric inhibition with neuromodulation to enhance stroke rehabilitation
Keywords: گابا; Interhemispheric inhibition; Stroke; Rehabilitation; Neuromodulation; Transcranial magnetic stimulation; Electrical stimulation; TMS; Transcranial magnetic stimulation; rTMS; repetitive transcranial magnetic stimulation; GABA; γ-amino butyric acid; tDCS;
GABAA receptor expression and white matter disruption in intrauterine growth restricted piglets
Keywords: گابا; GABA; Neuronal injury; Myelin; Low birth weight; Placental insufficiency;
Semicarbazide disturbs the reproductive system of male zebrafish (Danio rerio) through the GABAergic system
Keywords: گابا; BSI; brain-somatic index; CYP; cytochrome P450; E2; 17β-estradiol; ELISA; enzyme-linked immunosorbent; FSH; follicle-stimulating hormone; fshr; FSH receptor; GABA; γ-aminobutyric acid; GAD; glutamate decarboxylase; gabaa; GABA A receptor; gabab; GABA B
Pharmacological characterization of histamine-gated chloride channels from the housefly Musca domestica
Keywords: گابا; ACh; acetylcholine; AChR; ACh receptor; Am; amthamine; Cho; choline; DA; dopamine; GABA; γ-aminobutyric acid; GABACl; GABA-gated chloride channel; GABAR; GABA receptor; Glu; l-glutamate; GluCl; Glu-gated chloride channel; HA; histamine; HACl; HA-gated ch
Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis
Keywords: گابا; CC1; anti-adenomatours polyposis coli clone CC1; CD11b; cluster of differentiation molecule 11B; CFA; complete Freund adjuvant; DHP; dihydroprogesterone; EAE; experimental autoimmune encephalomyelitis; Fis1; mitochondrial fission 1; GABA; gamma-aminobutyr
Influence of exogenous chemicals on larval development and survival of the king scallop Pecten maximus (L.)
Keywords: گابا; ACH; Acetylcholine chloride; ANOVA; Analysis of variance; GABA; γ-Aminobutyric acid; l-DOPA; l-3,4-Dihydroxyphenylalanine; KCl; Potassium chloride; M; Molar; NH4Cl; Ammonium chloride; Pecten maximus; Larvae; Chemical induction; Metamorphosis; Survival;
Betaine attenuates memory impairment after water-immersion restraint stress and is regulated by the GABAergic neuronal system in the hippocampus
Keywords: گابا; Water-immersion restraint stress; Betaine; Memory; γ-Amino butyric acid; GABA; Hippocampus;
Rho-kinase inhibitor prevents acute injury against transient focal cerebral ischemia by enhancing the expression and function of GABA receptors in rats
Keywords: گابا; ROCK; Hydroxyfasudil; Transient middle cerebral artery occlusion (tMCAO); LTP; GABA;
L-theanine prevent quinolinic acid induced motor deficit and striatal neurotoxicity: Reduction in oxido-nitrosative stress and restoration of striatal neurotransmitters level
Keywords: گابا; Catecholamines; Huntington's disease; GABA; Glutamate; Oxidative stress; L-theanine;
Anti-hyperalgesic effect of Lippia grata leaf essential oil complexed with β-cyclodextrin in a chronic musculoskeletal pain animal model: Complemented with a molecular docking and antioxidant screening
Keywords: گابا; 5-HT; 5-hydroxytryptamine; CDs; Cyclodextrins; CNS; Central Nervous System; DLF; dorsolateral funiculus; DPPH; 2,2-diphenyl-1-picryl-hydrazyl-hydrate; FM; Fibromyalgia; GABA; gamma-aminobutyric acid; LC; Locus ceruleus; LG; L. grata leaf essential oil; LG
Identification of eugenol as the major determinant of GABAA-receptor activation by aqueous Syzygium aromaticum L. (clove buds) extract
Keywords: گابا; Acetyleugenol; Analgesic activity; Clove buds; Eugenol; GABAA receptor; Two-electrode voltage clamp technique; γ-Amino butyric acid; GABA; (ultra) high-performance liquid chromatography; (U)HPLC; gas chromatography; GC; two-electrode voltage clamp; TEVC;
Chronic lurasidone treatment normalizes GABAergic marker alterations in the dorsal hippocampus of mice exposed to prenatal immune activation
Keywords: گابا; Poly(I:C); Infection; GABA; Hippocampus; Lurasidone; BDNF;
Wavy multistratified amacrine cells in the monkey retina contain immunoreactive secretoneurin
Keywords: گابا; Neuropeptide; GABA; Primate; Melanopsin; Color vision;
Allosteric modulation of nicotinic and GABAA receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model
Keywords: گابا; Autism; BTBR; GABA; Nicotinic; Allosteric modulator;
The role of IL-6 in neurodevelopment after prenatal stress
Keywords: گابا; IL-6; Microglia; Prenatal stress; Gaba; Embryonic;
P/Q-type voltage-gated calcium channels mediate the ethanol and CRF sensitivity of central amygdala GABAergic synapses
Keywords: گابا; Alcohol/ethanol; Central amygdala; Corticotropin-releasing factor (CRF); Corticotropin-releasing factor type 1 receptor (CRF1); GABA; P/Q-type voltage-gated calcium channel; Alcohol dependence; 5HT-2C; 5-hydroxytryptomine-2C; aCSF; artificial cerebrospina
Semicarbazide-induced thyroid disruption in Japanese flounder (Paralichthys olivaceus) and its potential mechanisms
Keywords: گابا; SMC; Semicarbazide; HPT axis; hypothalamic-pituitary-thyroid axis; GABA; gamma-aminobutyric acid; THs; thyroid hormones; T3; 3,5,3â²-triiodothyronine; T4; thyroxine; TSH; thyroid-stimulating hormone; CRH; corticotropin-releasing hormone; TRH; thyrotropin
4,5-Dichloro-2-octyl-4-isothiazolin-3-one (DCOIT) modifies synaptic transmission in hippocampal CA3 neurons of rats
Keywords: گابا; 4,5-Dichloro-2-octyl-4-isothiazolin-3-one (DCOIT); Neurotransmission; Synaptic currents; GABA; Glutamate; Ca2+;
Mapping in mice the brain regions involved in the anxiolytic-like properties of α-casozepine, a tryptic peptide derived from bovine αs1-casein
Keywords: گابا; α-CZP; α-casozepine; AIS; anxiety-inducing situation; BNST; bed nucleus of the stria terminalis; BZD; benzodiazepine; CH; tryptic hydrolysate of bovine αs1-casein; CS; control situation; GABA; γ-amino butyric acid; i.p.; intraperitoneal; LDB; light/da
Parafascicular thalamic nucleus deep brain stimulation decreases NMDA receptor GluN1 subunit gene expression in the prefrontal cortex
Keywords: گابا; APV; 2-amino-5-phosphonopentanoic acid; CM-PF; centromedian-parafascicular; Cg1; cingulate cortex, area 1; PrL; prelimbic cortex; DBS; deep brain stimulation; GABA; glutamate-gamma-aminobutyric acid; LTP; long-term potentiation; LTD; long-term depression;
Exposure to prolonged controllable or uncontrollable stress affects GABAergic function in sub-regions of the hippocampus and the amygdala
Keywords: گابا; TWS; two way shuttle; dDG; dorsal dentate gyrus; vDG; ventral dentate gyrus; dCA1; dorsal CA1; vCA1; ventral CA1; Stress controllability; GABA; Neuropeptide Y; Glutamate decarboxylase (GAD)65; Cholecystokinin; Hippocampus; Dentate gyrus; Basolateral amygd
Physiological reviewNot a single but multiple populations of GABAergic neurons control sleep
Keywords: گابا; Slow wave sleep; Paradoxical sleep; GABAa receptors; GABA; Glycine; Muscle atonia; EEG;
Research PaperAltered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia
Keywords: گابا; BDNF; brain-derived neurotrophic factor; CAVII; cytosolic carboanhydrase isotyp 7; GABAAR; GABAA receptor; IN; interneurons; PV; parvalbumin; KCC2; potassium chloride transporter 2; Basal ganglia; Fast spiking interneurons; Parvalbumin; GABA; Striatum; BD
Research PaperVentral medullary control of rapid eye movement sleep and atonia
Keywords: گابا; REM arousal; GABA; VGAT; DREADD; AAV;
Investigating TMS-EEG Indices of Long-Interval Intracortical Inhibition at Different Interstimulus Intervals
Keywords: گابا; Transcranial magnetic stimulation; Electroencephalography; Long-interval intracortical inhibition; Interstimulus interval; TMS-evoked potential; GABA; EEG; electroencephalography; EMG; electromyography; FDI; first dorsal interosseous; GABA; gamma-aminobut
Disruption of brain MEK-ERK sequential phosphorylation and activation during midazolam-induced hypnosis in mice: Roles of GABAA receptor, MEK1 inactivation, and phosphatase MKP-3
Keywords: گابا; Cdk5; cyclin-dependent kinase-5; ERK; extracellular signal-regulated kinase; GABA; γ-aminobutyric acid; MAPK; mitogen-activated protein kinase; MEK; MAPK kinase; MKP; MAPK phosphatase; LORR; loss of the righting reflex; RORR; recovery of the righting ref
Pre-treatment with melatonin decreases abamectin induced toxicity in a nocturnal insect Spodoptera litura (Lepidoptera: Noctuidae)
Keywords: گابا; CAT; catalase; POX; peroxidase; SOD; superoxide dismutase; AI; active ingredient; LPO; lipid peroxidation; GABA; gamma-aminobutyric acid; GluCl; glutamate-gated chloride channel; PM; pre-melatonin group; TM; post-melatonin group; GPx; glutathione Peroxida
Behavioral effects and neuroanatomical targets of acute atrazine exposure in the male Sprague-Dawley rat
Keywords: گابا; Dopamine; c-Fos; GABA; Glutamate; Locomotor activity; Herbicides;