The role of IL-6 in neurodevelopment after prenatal stress
Keywords: گابا; IL-6; Microglia; Prenatal stress; Gaba; Embryonic;
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Exposure to prolonged controllable or uncontrollable stress affects GABAergic function in sub-regions of the hippocampus and the amygdala
Keywords: گابا; TWS; two way shuttle; dDG; dorsal dentate gyrus; vDG; ventral dentate gyrus; dCA1; dorsal CA1; vCA1; ventral CA1; Stress controllability; GABA; Neuropeptide Y; Glutamate decarboxylase (GAD)65; Cholecystokinin; Hippocampus; Dentate gyrus; Basolateral amygd
Research PaperAltered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia
Keywords: گابا; BDNF; brain-derived neurotrophic factor; CAVII; cytosolic carboanhydrase isotyp 7; GABAAR; GABAA receptor; IN; interneurons; PV; parvalbumin; KCC2; potassium chloride transporter 2; Basal ganglia; Fast spiking interneurons; Parvalbumin; GABA; Striatum; BD
Research PaperVentral medullary control of rapid eye movement sleep and atonia
Keywords: گابا; REM arousal; GABA; VGAT; DREADD; AAV;
Allosteric modulation of nicotinic and GABAA receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model
Keywords: گابا; Autism; BTBR; GABA; Nicotinic; Allosteric modulator;
Investigating TMS-EEG Indices of Long-Interval Intracortical Inhibition at Different Interstimulus Intervals
Keywords: گابا; Transcranial magnetic stimulation; Electroencephalography; Long-interval intracortical inhibition; Interstimulus interval; TMS-evoked potential; GABA; EEG; electroencephalography; EMG; electromyography; FDI; first dorsal interosseous; GABA; gamma-aminobut
Disruption of brain MEK-ERK sequential phosphorylation and activation during midazolam-induced hypnosis in mice: Roles of GABAA receptor, MEK1 inactivation, and phosphatase MKP-3
Keywords: گابا; Cdk5; cyclin-dependent kinase-5; ERK; extracellular signal-regulated kinase; GABA; γ-aminobutyric acid; MAPK; mitogen-activated protein kinase; MEK; MAPK kinase; MKP; MAPK phosphatase; LORR; loss of the righting reflex; RORR; recovery of the righting ref
Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATPα
Keywords: گابا; Dup15q; Duplication 15q syndrome; GABA; Gamma-aminobutyric acid; Ube3a; Ubiquitin-protein ligase E3A (also known as E6AP); Dube3a; Drosophila homolog of Ube3a; AS; Angelman syndrome; ATPα; Na+, K+-ATPase α-subunit; MB; mushroom body; ERGs; Electroretino
ACC GABA levels are associated with functional activation and connectivity in the fronto-striatal network during interference inhibition in patients with borderline personality disorder
Keywords: گابا; Borderline personality disorder; Interference inhibition; Anterior cingulate cortex; GABA; Fronto-striatal networks; impulsivity;
Research PaperIntranasal cotinine improves memory, and reduces depressive-like behavior, and GFAPÂ + cells loss induced by restraint stress in mice
Keywords: گابا; ANOVA; Analysis of variance; BDNF; Brain derived neurotrophic factor; CS; Conditioned Stimulus; EPM; Elevated plus maze; GDNF; glial derived neurotrophic factor; GABA; Gamma-Amino Butyric acid; ÎΣÎ3β; Glycogen synthase kinase 3 beta; HPA; Hypothalamus
Research PaperSurvival of iPSC-derived grafts within the striatum of immunodeficient mice: Importance of developmental stage of both transplant and host recipient
Keywords: گابا; BDNF; brain derived neurotrophic factor; DAPI; 4â²,6-diamidino-2-phenylindole; Dkk1; Dikkopf 1; ESC; embryonic stem cell; GABA; gamma-aminobutyric acid; HD; Huntington's disease; IBSN; infantile bilateral striatal necrosis; iNSC; iPSC-derived neural stem
Archival Report7T Proton Magnetic Resonance Spectroscopy of Gamma-Aminobutyric Acid, Glutamate, and Glutamine Reveals Altered Concentrations in Patients With Schizophrenia and Healthy Siblings
Keywords: گابا; First-degree relatives; GABA; Glutamate; Glutamine; Magnetic resonance spectroscopy; Schizophrenia;
Increasing spinal 5-HT2A receptor responsiveness mediates anti-allodynic effect and potentiates fluoxetine efficacy in neuropathic rats. Evidence for GABA release
Keywords: گابا; ANOVA; analysis of variance; α-methyl-5-HT; alpha-methyl-5-hydroxy-tryptamine maleate; AUC; area under the curve; CCI; chronic constriction injury; DMSO; dimethylsulfoxyde; GABA; gamma amino butyric acid; HPLC; high performance liquid chromatography; i.m
Neuropharmacological and neuroprotective activities of some metabolites produced by cell suspension culture of Waltheria americana Linn.
Keywords: گابا; Waltheria americana; Cell culture; Neuroprotective; GABA;
Knockout of sodium pump α3 subunit gene (Atp1a3â/â) results in perinatal seizure and defective respiratory rhythm generation
Keywords: گابا; 3-MT; 3-methocytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; 5-hydroxytryptamine; AHC; alternating hemiplegia of childhood; ATP1A3 or Atp1a3; gene for sodium pump α3 subunit of human or mouse, respectively; Atp1a3; homozygous knockout mice of Atp
Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells
Keywords: گابا; Cerebellum; Axon collateral; GABA; Synaptic modulation; Serotonin; Noradrenaline; ACSF; artificial cerebrospinal fluid; GABA; γ-aminobutyric acid; 5-HT; serotonin; mIPSC; miniature inhibitory postsynaptic current; NA; noradrenaline; PC; Purkinje cell; sI
Inhibition of Nkcc1 promotes axonal growth and motor recovery in ischemic rats
Keywords: گابا; BBB; blood-brain-barrier; BDA; biotinylated dextran amine; CST; corticospinal tract; DAPI; 4,6-diamino-2-phenyl indole; ET-1; endothelin-1; GABA; Gamma-aminobutyric acid; KCC2; K+-Clâ-co-transporter 2; LSD; least significant difference; MAG; myelin-as
The major neurotransmitter systems in the basolateral amygdala and the ventral tegmental area mediate morphine-induced memory consolidation impairment
Keywords: گابا; ANOVA; analysis of variance; ACPA; arachidonylcyclopropylamide; GABA; gamma-Aminobutyric acid; NMDA; N-methyl-d-aspartate; S.E.M; standard error of mean; morphine amnesia; neurotransmitter systems; basolateral amygdala; ventral tegmental area; rat(s);
Purinergic P2 receptors in the paraventricular nucleus of the hypothalamus are involved in hyperosmotic-induced sympathoexcitation
Keywords: گابا; aCSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; ATP; adenosine 5â²-triphosphate; AVP; arginine vasopressin; GABA; glutamate, γ-aminobutyric acid; LSNA; lumbar sympathetic nerve activity; MnPO; median preoptic nucleus; NO; nitric oxide
Disruption of 5-HT2A-PDZ protein interaction differently affects the analgesic efficacy of SSRI, SNRI and TCA in the treatment of traumatic neuropathic pain in rats
Keywords: گابا; Neuropathic pain; Mechanical hyperalgesia; 5-HT2A receptors; PDZ proteins; Fluoxetine; Duloxetine; Clomipramine; GABA; Alpha-methyl-5-hydroxy-tryptamine maleate (PubChem CID: 2107); M100907 (PubChem CID: 60858); Bicuculline (PubChem CID: 10237); Fluoxetin
Cellular circadian oscillators in the suprachiasmatic nucleus remain coupled in the absence of connexin-36
Keywords: گابا; Cx36; connexin-36; DD; constant darkness; EM; Explant Medium; GABA; γ-Aminobutyric acid; LD; LD12:12 light/dark cycle (12-h light, 12-h dark); LL; constant light; mPer2Luc; PERIOD2::LUCIFERASE; Per2; Period 2; SCN; Suprachiasmatic nucleus; TTL; transcrip
Enkephalin and neuropeptide-Y interaction in the intergeniculate leaflet network, a part of the mammalian biological clock
Keywords: گابا; ACSF; artificial cerebro-spinal fluid; AP-5; 2-amino-5-phosphonopentanoic acid; Bic; bicuculline methiodide; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; EGTA; ethylene glycol tetraacetic acid; ENK; enkephalin; GABA; γ-aminobutyric acid; GGT; geniculo-gen
Auditory thalamic circuits and GABAA receptor function: Putative mechanisms in tinnitus pathology
Keywords: گابا; Tinnitus; Auditory thalamus; Medial geniculate body; GABAA receptor; Thalamocortical dysrhythmia; AAC; auditory association cortex; AI; primary auditory cortex; Ca2+; calcium; GABA; g-amino butyric acid; GBX; gaboxadol; IC; inferior colliculus; MGB; media
Opioid-induced rewards, locomotion, and dopamine activation: A proposed model for control by mesopontine and rostromedial tegmental neurons
Keywords: گابا; μOR; mu opioid receptor; ACh; acetylcholine; AChR; acetylcholine receptor; ChAT; choline acetyltransferase; CPP; conditioned place preference; DA; dopamine; DREADD; designer receptors exclusively activated by designer drugs; GABA; gamma-aminobutyric acid
The impact of GABAergic drugs on TMS-induced brain oscillations in human motor cortex
Keywords: گابا; Electroencephalography; Pharmaco-TMS-EEG; GABA; Transcranial magnetic stimulation; Oscillations;
Review articleZolpidem's use for insomnia
Keywords: گابا; CAP; cyclic alternating pattern; Cmax; maximum plasma concentration; CNS; central nervous system; ER; extended-release; GABA; γ-aminobutyric acid; GAD; generalized anxiety disorder; IR; immediate-release; LPS; latency to persistent sleep; MDD; major depr
Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy
Keywords: گابا; AEDs; antiepileptic drugs; ANOVA; analysis of variance; AP-1; activator protein 1; BBB; blood brain barrier; CA; Cornu Ammonis; COX-2; cyclooxygenase-2; CBZ; carbamazepine; EEG; electroencephalography; GABA; gamma-aminobutyric acid; HMGB1; High Mobility G
Assessment of intra- and inter-regional interrelations between GABA+, Glx and BOLD during pain perception in the human brain - A combined 1H fMRS and fMRI study
Keywords: گابا; 1H; proton; BOLD; blood oxygenation level dependent; CSF; cerebral spinal fluid; EPI; echo planar imaging; fMRI; functional magnetic resonance imaging; fMRS; functional magnetic resonance spectroscopy; FWE; family wise error; FWHM; full width at half maxi
Evaluation of the rotenone-induced activation of the Nrf2 pathway in a neuronal model derived from human induced pluripotent stem cells
Keywords: گابا; Human induced pluripotent stem cells; Neuronal/glial cultures; Nrf2 pathway; Rotenone; AOPs; Adverse Outcome Pathways; ARE; Antioxidant-Responsive-Element; GABA; Gamma-Aminobutyric Acid; GABRA1; Gamma-Aminobutyric Acid Type A Receptor Alpha1 Subunit; GABR
Oxytocin in the medial prefrontal cortex attenuates anxiety: Anatomical and receptor specificity and mechanism of action
Keywords: گابا; Medial prefrontal cortex; Amygdala; Anxiety; GABA; Prelimbic; Oxytocin;
Prefrontal cortical GABAergic signaling and impaired behavioral flexibility in aged F344 rats
Keywords: گابا; ANOVA; analysis of variance; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol-bis(2-aminoethylether)-N,N,Nâ²,Nâ²-tetraacetic acid; GABA; gamma-aminobutyric acid; GABA(B)R; GABA(B) receptor; HEPES; 4-(2-hydroxyethyl)piperazine-1-ethanesulfoni
Neural inhibition can explain negative BOLD responses: A mechanistic modelling and fMRI study
Keywords: گابا; fMRI; Neurovascular coupling; GABA; glutamate; Cerebral blood flow; Blood oxygen level dependent response; Hemodynamic response; Systems biology;
Research PaperComplete spinal cord injury (SCI) transforms how brain derived neurotrophic factor (BDNF) affects nociceptive sensitization
Keywords: گابا; aCSF; artificial cerebrospinal fluid; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; Cap; capsaicin; CNS; central nervous system; EMR; enhanced mechanical reactivity; ERK; extracellular signal-regulated kinases; GABA; Gamma-aminobutyr
Synergistic antipruritic effects of gamma aminobutyric acid AÂ and B agonists in a mouse model of atopic dermatitis
Keywords: گابا; Atopic dermatitis; baclofen; chronic itch; GABA; GABAergic progenitor cell transplants; muscimol; pruritogens; AD; Atopic dermatitis; CQ; Chloroquine; ED50; Median effective dose; GABA; Gamma aminobutyric acid; GAD; Glutamic acid decarboxylase; GFP; Green
Protective effect of naringin on pentylenetetrazole (PTZ)-induced kindling; possible mechanisms of antikindling, memory improvement, and neuroprotection
Keywords: گابا; Naringin; Pentylenetetrazole (PTZ); Kindling; Oxidative stress; Glutamate; GABA; Hippocampus and Y maze;
Role of low-voltage-activated calcium current and extracellular calcium in controlling the firing pattern of developing CA1 pyramidal neurons
Keywords: گابا; ACSF; artificial cerebrospinal fluid; ADP; spike after-depolarization; AP; action potential; BAPTA; 1,2-bis (2-aminophenoxy) ethane N,N,Nâ²,Nâ²-tetraacetic acid; BS; burst-spiking; EGTA; ethylene glycol tetraacetic acid; GABA; γ-aminobutyric acid; HVA;
Review articleTheiler's murine encephalomyelitis virus infection of SJL/J and C57BL/6J mice: Models for multiple sclerosis and epilepsy
Keywords: گابا; AMPA; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate; APCs; Antigen presenting cells; BBB; Blood-brain barrier; CNS; Central nervous system; CSF; Cerebrospinal fluid; DA; Daniels; EAE; Experimental autoimmune encephalomyelitis; GABA; γ-Aminobutyric ac
The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABAB receptor with a potential for treatment of anxiety, pain and spasticity
Keywords: گابا; Allosteric modulator; GABA; Anxiety; Pain; Body temperature; Baclofen; Spasticity; Clinical candidate; GABA (PubChem CID: 119); (R)-Baclofen (PubChem CID: 44602); Diazepam (PubChem CID: 3016); Chlordiazepoxide (PubChem CID: 2712);
Cysteine-rich whey protein isolate (Immunocal®) ameliorates deficits in the GFAP.HMOX1 mouse model of schizophrenia
Keywords: گابا; ADHD; attention deficit-hyperactivity disorder; ANOVA; analysis of variance; BDD; boron-doped diamond; BSA; bovine serum albumin; BV; biological value; cDNA; complementary deoxyribonucleic acid; CNS; central nervous system; DA; dopamine; DAPI; 4â², 6-dia
The medullary dorsal reticular nucleus as a relay for descending pronociception induced by the mGluR5 in the rat infralimbic cortex
Keywords: گابا; AMG; AMG 9810 (TRPV1 antagonist); ANOVA; analysis of variance; ARTH; kaolin/carrageenan induced monoarthritis; CHPG; (RS)-2-Chloro-5-hydroxyglycine (mGluR5 agonist); CNS; central nervous system; DRt; dorsal reticular nucleus; GABA; γ-aminobutyric acid; i
The binding orientations of structurally-related ligands can differ; AÂ cautionary note
Keywords: گابا; Cys-loop; Ion channel; Receptor; Radioligand; 5-HT3; Agonist; Antagonist; Crystal; Binding; Granisetron; Tropisetron; Ligand; Structure; Synthesis; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryon
Electrophysiological characterization of the M-current in rat hypoglossal motoneurons
Keywords: گابا; ACh; acetylcholine; AP; action potential; APV; (2R)-amino-5-phosphonovaleric acid; DHβE; dihydro-β-erythroidine; DNQX; 6,7-dinitroquinoxaline-2,3-dione; EK; potassium equilibrium potential; GABA; γ-aminobutyric acid; HM; hypoglossal motoneuron; Ih; hyp
Kynurenine pathway metabolism and the microbiota-gut-brain axis
Keywords: گابا; Tryptophan; Kynurenine; Stress; Immune system; Microbiota-gut-brain-axis; Behaviour; BBB; blood brain barrier; CNS; central nervous system; DSM; diagnostic and statistical manual; ENS; enteric nervous system; GABA; gamma-aminobutyric acid; GF; germfree; G
Big GABA: Edited MR spectroscopy at 24 research sites
Keywords: گابا; Editing; GABA; MEGA-PRESS; MRS; Multi-site study;
Research PaperA rapid chemical-genetic screen utilizing impaired movement phenotypes in C. elegans: Input into genetics of neurodevelopmental disorders
Keywords: گابا; ASD; autism spectrum disorder; NDD; neurodevelopmental disorders; ADHD; attention deficit hyperactivity disorders; WT; wildtype; SNPs; single nucleotide polymorphism; SFARI; Simons Foundation Autism Research Initiative; GABA; γ-aminobutyric acid; RNAi; R
Disinhibition of the intergeniculate leaflet network in the WAG/Rij rat model of absence epilepsy
Keywords: گابا; AP-5; 2-amino-5-phosphonopentanoic acid; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; DLG; dorsal part of the lateral geniculate complex; ENK; enkephalin; GABA; γ-amino butyric acid; GFAP; glial fibrillary acidic protein; IA; A-type potassium current; IGL
Synaptic targets: Chronic alcohol actions
Keywords: گابا; Alcohol/ethanol; GABA; Glutamate; Synaptic transmission; Presynaptic; Postsynaptic; Protein phosphorylation; Intoxication; Tolerance; Dependence;
Research reportImplications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function
Keywords: گابا; GABA; γ-aminobutyric acid; SPAK; Ste20-related proline-alanine-rich kinase; HA-SPAK; hemagglutinin-tagged SPAK protein; OSR1; oxidative stress responsive kinase; DNSPAK; dominant negative form of SPAK; Intracellular chloride; KCC2; GABA; Inhibition; SPAK
Nitric oxide-coupled signaling in odor elicited molecular events in the olfactory center of the terrestrial snail, Helix pomatia
Keywords: گابا; 5-HT; 5-hydroxytryptamine or serotonin; ACh; acetylcholine; AGC-S-P; phosphorylated substrate of the AGC-family protein kinase; Akt; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APV; (2R)-amino-5-phosphonovaleric acid; B
Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits
Keywords: گابا; AN40; auditory N40; CFC; cross-frequency coupling; ROI; region of interest; Gamma; 30-100Â Hz electrophysiological activity; ASSR; auditory steady-state response; SNR; signal to noise ratio; PWC; pairwise comparison; GABA; Gamma-band; Baclofen; ASD; Pcd