Keywords: جوجه‌تیغی، خارپشت; PNBPPSKEUWGJOT-UHFFFAOYSA-N; AEBVEQJVBUJBDW-UHFFFAOYSA-NAmide derivatives; Hedgehog; Smoothened antagonist
مقالات ISI جوجه‌تیغی، خارپشت (ترجمه نشده)
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Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Smoothened; Patched; Metabolites; Sterols; Oxysterols;
Keywords: جوجه‌تیغی، خارپشت; BMP; Wnt; FGF; IGF; Hedgehog; Retinoic acid; Smad; Suppressor-of-fused; HtrA1; CNS; Xenopus;
Keywords: جوجه‌تیغی، خارپشت; CAFs; cancer-associated fibroblasts; CCA; cholangiocarcinoma; DAPI; 4â²-6-diamidino-2-phenylindole; FBS; fetal bovine serum; Hh; Hedgehog; Gli; glioma-associated transcriptional factor; Ptch1; Patched-1; PTX; pertussis toxin; qRT-PCR; quantitative revers
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Wnt; Primary mouth; Xenopus; Mouse; Buccopharyngeal membrane; Stomodeum; Fibronectin;
Keywords: جوجه‌تیغی، خارپشت; Gli; Hedgehog; Morphogen; Development;
Keywords: جوجه‌تیغی، خارپشت; LPC; liver progenitor cell; Hh; Hedgehog; SHH; Sonic Hedgehog; IHH; Indian Hedgehog; DHH; Desert Hedgehog; PTCH1; Patched 1; SMO; Smoothened; GLI; GLI-Kruppel family of transcription factors; GLI-A; GLI full-length activator; Pc; primary cilia; TAA; thioa
Keywords: جوجه‌تیغی، خارپشت; Neural crest; Development; BMP; Wnt; Hedgehog; Craniofacial anomaly
Keywords: جوجه‌تیغی، خارپشت; Cell signaling; Combination chemotherapy; Novel antitumor agents; Hedgehog; Smoothened; Targeted therapy;
Keywords: جوجه‌تیغی، خارپشت; aSMA; alpha smooth muscle actin; BMP-7; bone morphogenic protein-7; EMT; epithelial-to-mesenchymal transition; GFAP; glial fibrillary acidic protein; Gli; glioblastoma; Hh; hedgehog; HSC; hepatic stellate cell; MF; myofibroblast; Ptc; patched; Smo; smooth
Keywords: جوجه‌تیغی، خارپشت; Development; Hedgehog; Signaling; Processing; Secretion
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Cyclopamine; Smoothened agonist (SAG); Purmorphamine (PMA); Gli1; Gli3; Dorsal aorta;
Keywords: جوجه‌تیغی، خارپشت; Cyclic hypoxia; Metastasis; Cervix; CXCR4; Hedgehog;
Keywords: جوجه‌تیغی، خارپشت; BrdU; bromodeoxyuridine; Cdk; cyclin-dependent kinase; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle medium; Myo7a; myosin VIIA; P2; postnatal day 2; Pax2; paired box 2; pRb; retinoblastoma protein; Ptc; patched; Rb1; retinoblas
Keywords: جوجه‌تیغی، خارپشت; GATA; Friend of GATA; JAK/STAT; Bone morphogenic protein; Hedgehog; Hematopoiesis;
Keywords: جوجه‌تیغی، خارپشت; Cancer stem cells; Notch; Hedgehog; Wnt;
Keywords: جوجه‌تیغی، خارپشت; QT interval; ECG; hedgehog; heart; cardiac evaluation
Keywords: جوجه‌تیغی، خارپشت; Atelerix albiventris; hedgehog; thyroid tumor; neoplasia; radiation therapy
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Sulfation; Enzymatic efficiency; Interspecies difference
Enhanced radiosensitization of human glioblastoma multiforme cells with phosphorylated peptides derived from Gli2
Keywords: جوجه‌تیغی، خارپشت; Gli2; Hedgehog; Peptides; Radiosensitization; GBM;
Sinomenine reduces growth and metastasis of breast cancer cells and improves the survival of tumor-bearing mice through suppressing the SHh pathway
Keywords: جوجه‌تیغی، خارپشت; Hh; Hedgehog; SMO; smoothened; Ptch1; Patched 1 receptor 1; SHh; sonic hedgehog; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; EMT; epithelial-mesenchymal transition; qPCR; quantitative polymerase chain reaction; IHC; hematoxylin
Feeding the Hedgehog: A new meaning for JNK signalling in liver regeneration
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; JNK; IHH; ALPPS; Liver regeneration;
ESCRT genes and regulation of developmental signaling
Keywords: جوجه‌تیغی، خارپشت; ABA; abscisic acid; AUX1; AUXIN-RESISTANT1; CHMP; charged multivesicular body protein; Crb; crumbs; DSL; delta/serrate/lag-2; Dx; Deltex; Dome; domeless; Dpp; decapentaplegic; EGFR; epidermal growth factor receptor; ESCRT; endosomal sorting complex requir
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: جوجه‌تیغی، خارپشت; 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions
Keywords: جوجه‌تیغی، خارپشت; 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-
Epigenetic regulation of the Hedgehog and Wnt pathways in cancer
Keywords: جوجه‌تیغی، خارپشت; Cancer; Epigenetics; Hedgehog; Wnt; Methylation; Histone modifications; Micro RNA;
Clotting protein - An extracellular matrix (ECM) protein involved in crustacean hematopoiesis
Keywords: جوجه‌تیغی، خارپشت; Clotting protein; ECM; Hematopoiesis; Crustacean; Ast1; Astakine 1; CP; clotting protein; ECM; extracellular matrix; Hg; Hedgehog; HPT; hematopoietic tissue; TGase; transglutaminase; Trol; heparin sulfate proteoglycan Terribly Reduced Optic Lobes;
MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis
Keywords: جوجه‌تیغی، خارپشت; ApoB; apolipoprotein B; CBDL; common bile duct ligation; CCl4; carbon tetrachloride; CPT1; peroxisome carnitine palmitoyl transferase 1; CREBH; cAMP responsive element binding protein H; DNL; de novo lipogenesis; ECM; extracellular matrix; ER; endoplasmic
JNK1 induces hedgehog signaling from stellate cells to accelerate liver regeneration in mice
Keywords: جوجه‌تیغی، خارپشت; Compensatory hypertrophy; Small-for-size syndrome; Future liver remnant; Hedgehog; JNK1;
Endocrine and physiological regulation of neutral fat storage in Drosophila
Keywords: جوجه‌تیغی، خارپشت; Lipid metabolism; Drosophila; Obesity; Insulin; TOR; Ecdysone; AGPAT; acylglycerol-3-phosphate acyltransferase; AKH; adipokinetic hormone; BMM; Brummer; CC; corpora cardiac; DAG; diacylglycerol; Dilp; Drosophila insulin-like peptide; DGAT; diacylglycerol
Biogenesis and function of ESCRT-dependent extracellular vesicles
Keywords: جوجه‌تیغی، خارپشت; Aβ; amyloid-β protein; Acb1; acyl CoA binding protein1; ALIX; ALG-2 interacting protein X; APP; amyloid precursor protein; ARRDC1; ARRestin domain-containing protein 1; COPI/II; coat protein complex I/II; CUPS; compartment for unconventional protein sec
Carcinogenicity assessment of the Hedgehog pathway inhibitor, vismodegib in Tg.rasH2 mice and Sprague-Dawley rats
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Vismodegib; Carcinogenicity; Pilomatricoma; Keratoacanthoma;
Antitumor Efficacy of Dual Blockade of EGFR Signaling by Osimertinib in Combination With Selumetinib or Cetuximab in Activated EGFR Human NCLC Tumor Models
Keywords: جوجه‌تیغی، خارپشت; Osimertinib; MEK; Hedgehog; Lung cancer; Animal models of cancer;
Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo
Keywords: جوجه‌تیغی، خارپشت; Hedgehog inhibitor; In vivo pharmacokinetics; Gram-scale synthesis; ADME-Tox; LS180 xenograft; Acylguanidine; Hh; Hedgehog; Shh; Sonic Hedgehog; Ptch; Patched; Smo; Smoothened; BCC; basal cell carcinoma; PE; petroleum ether; SRB; sulforhodamine B; Shh-CM
HHIPL-1 (rs2895811) gene polymorphism is associated with cardiovascular risk factors and cardiometabolic parameters in Mexicans patients with myocardial infarction
Keywords: جوجه‌تیغی، خارپشت; BMI; body mass index; CAC; coronary artery calcium; CAD; coronary artery disease; COPD; chronic obstructive pulmonary disease; Dhh; desert hedgehog; HDL-C; high-density lipoprotein cholesterol; Hh; hedgehog; HHIPL-1; hedgehog interacting protein-like 1; H
Discovery and characterization of a potent Wnt and hedgehog signaling pathways dual inhibitor
Keywords: جوجه‌تیغی، خارپشت; Wnt signaling pathway; Hedgehog signaling pathway; Porcupine; Smoothened; Antagonist; Stem cell; Cancer therapy; AUC; area under the plasma time-concentration curve; BCC; basal cell carcinoma; BPO; benzoyl peroxide; CL; clearance; CSC; cancer stem cells;
Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells
Keywords: جوجه‌تیغی، خارپشت; Apoptosis; Cell death; Noxa; TAp73; EGR1; GANT61; Hedgehog signaling; Rhabdomyosarcoma; Medulloblastoma; ARMS; alveolar RMS; CNS; central nervous system; DSMZ; Deutsche Sammlung von Mikroorganismen und Zellkulturen; EGR1; early growth response protein 1;
The ubiquitin ligase ITCH coordinates small intestinal epithelial homeostasis by modulating cell proliferation, differentiation, and migration
Keywords: جوجه‌تیغی، خارپشت; AP; alkaline phosphatase; BrdU; bromodeoxyuridine; CBC; crypt base columnar; EDTA; ethylenediaminetetraacetic acid; EMT; epithelial mesenchymal transition; H&E; hematoxylin and eosin; Hh; hedgehog; IBD; inflammatory bowel disease; IHC; immunohistochemistr
The ciliary protein Rpgrip1l in development and disease
Keywords: جوجه‌تیغی، خارپشت; BB; Basal body; Bbs; Bardet-Biedl syndrome; C. elegans; Caenorhabditis elegans; CC; Coiled-Coil; Cep290; Centrosomal Protein 290; COACH; Cerebellar Vermis Aplasia Oligophrenia Congenital Ataxia Coloboma Hepatic Fibrosis; CRD; Cone Rod Dystrophy; Cux1; Cut
Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors
Keywords: جوجه‌تیغی، خارپشت; Wnt; Beta-catenin; Colorectal cancers; Gamma secretase; Hedgehog; Targeted therapy;
Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease
Keywords: جوجه‌تیغی، خارپشت; ENS; Neural Development; Genetic Causes of HSCR; Family Study; bp; base pair; ENS; enteric nervous system; GDNF; glial cell-derived neurotrophic factor; GFP; green fluorescent protein; GLI1; GLI family zinc finger 1; GLI3; GLI family zinc finger 3; HEK;
Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium
Keywords: جوجه‌تیغی، خارپشت; BBS8; Bardet-Biedl syndrome 8; bFGF; basic fibroblast growth factor; BMP; bone morphogenetic protein; BMSCs; bone marrow-derived hematopoietic stem cells; ECM; extracellular matrix; EGF; epidermal growth factor; EMT; epithelial-to-mesenchymal transition;
High occurrence of mecC-MRSA in wild hedgehogs (Erinaceus europaeus) in Sweden
Keywords: جوجه‌تیغی، خارپشت; Methicillin resistance; MRSA; mecC; hedgehog; animal; Staphylococcus aureus;
Dorsal fin development in flounder, Paralichthys olivaceus: Bud formation and its cellular origin
Keywords: جوجه‌تیغی، خارپشت; Bud formation; Dorsal fin development; Flounder; Cell origin; Median fin; AEF; apical ectodermal fold; AER; apical ectodermal ridge; Col10a1; collagen type l0 alpha 1; DIG; digoxigenin; FGF8; Fibroblast growth factor 8; Hh; hedgehog; Hox; homeobox gene; M
Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Cilia; Neural retina; Retinal pigment epithelium; IFT172; IFT122;
Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis
Keywords: جوجه‌تیغی، خارپشت; AD; activation domain; CGNP; cerebellar granular neuron progenitor cells; CIP; calf intestinal alkaline phosphatase; DB; DNA-binding domain; EGCG; epigallocatechin gallate; FFPE; formalin-fixed, paraffin-embedded; H&E; hematoxylin/eosin staining; Hh; Hedg
Original research articleThree Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse
Keywords: جوجه‌تیغی، خارپشت; Tctn1; Tctn2; Tctn3; Hedgehog; Gli2; Gli3; Cilia;
Original research articlePKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant
Keywords: جوجه‌تیغی، خارپشت; Hedgehog; Gli2; Gli3; Talpid3; PKA; Cilia;
Mechanical stimulation promote the osteogenic differentiation of bone marrow stromal cells through epigenetic regulation of Sonic Hedgehog
Keywords: جوجه‌تیغی، خارپشت; Mechanical loading; BMSCs; Osteoblast differentiation; Hedgehog; DNA methylation;
Postzygotic Mutations in Beta-Actin Are Associated with Becker's Nevus and Becker's Nevus Syndrome
Keywords: جوجه‌تیغی، خارپشت; Hh; Hedgehog;