دانلود مقالات ISI درباره ژن PTEN + ترجمه فارسی

Protective effect of dioscin against intestinal ischemia/reperfusion injury via adjusting miR-351-5p-mediated oxidative stress

Keywords: ژن PTEN; II/R; intestinal ischemia-reperfusion; H/R; hypoxia-reoxygenation; IPC; ischemia-reperfusion precondition; IPO; ischemia-reperfusion post-conditioning; DIC; diffuse intravascular coagulation; SIRS; systemic inflammatory response syndrome; MODS; multiple o

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K pathway in prostate cancer: All resistant roads lead to PI3K

Keywords: ژن PTEN; CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Silver nanoparticles induce SH-SY5Y cell apoptosis via endoplasmic reticulum- and mitochondrial pathways that lengthen endoplasmic reticulum-mitochondria contact sites and alter inositol-3-phosphate receptor function

Keywords: ژن PTEN; Silver nanoparticles; SH-SY5Y cells; Endoplasmic reticulum stress; PTEN; Mitochondria-associated membranes; Inositol-3-phosphate receptor;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

HRD1-mediated PTEN degradation promotes cell proliferation and hepatocellular carcinoma progression

Keywords: ژن PTEN; PTEN; HRD1; HCC; Ubiquitination;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Metabolic reprogramming in colon cancer reversed by DHTS through regulating PTEN/AKT/HIF1α mediated signal pathway

Keywords: ژن PTEN; DHTS; dihydrotanshinone I; LCFAs; long-chain fatty acids; PTEN; phosphatase and tensin homolog gene; HIF1α; hypoxia inducible factor 1 alpha; HKII; hexokinase II; p-AKT; phosphorylated protein kinase B; RHEB; Ras homolog enriched in brain; SIRT3; Silent

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of heterochromatin stability on intestinal stem cell aging in Drosophila

Keywords: ژن PTEN; H3K9me3; tri-methyl histone H3 lysine9; H3K9me2; di-methyl histone H3 lysine9; HP1; heterochromatin protein 1; Su(var)3-9; suppressor of variegation 3-9; γH2AvD; phosphorylated Drosophila histone variant of H2A (Ser137); PH3; phosphorylated histone H3; J

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer

Keywords: ژن PTEN; Gold nanoparticle; Trastuzumab resistance; HER2; Gastric cancer; Autophagy; Tmab; trastuzumab; HER2; human epidermal growth factor receptor 2; AuNP; gold nanoparticle; ECD; extracellular domain; ADCC; antibody-dependent cellular cytotoxicity; PTEN; phosph

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

miR-19 targeting of PTEN mediates butyl benzyl phthalate-induced proliferation in both ER(+) and ER(−) breast cancer cells

Keywords: ژن PTEN; miR-19; Butyl benzyl phthalate; Breast cancer; PTEN; Proliferation;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Intraperitoneal nanotherapy for metastatic ovarian cancer based on siRNA-mediated suppression of DJ-1 protein combined with a low dose of cisplatin

Keywords: ژن PTEN; ovarian cancer; DJ-1; cisplatin; combinatorial therapy; siRNA; IV chemotherapy; intravenous chemotherapy; IP chemotherapy; intraperitoneal chemotherapy; PTEN; phosphatase and tensin homolog; p53; tumor suppressor protein 53; NRF2; nuclear factor (erythroi

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype

Keywords: ژن PTEN; TPP1; protein encoded by adrenocortical dysplasia gene; Acd; adrenocortical dysplasia gene; acd; adrenocortical dysplasia mutation; p53; transformation related protein 53; DNA; Deoxyribonucleic acid; DC; Dyskeratosis congenita; HHS; Hoyeraal-Hreidarsson s

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Novel nuclear translocation of inositol polyphosphate 4-phosphatase is associated with cell cycle, proliferation and survival

Keywords: ژن PTEN; INPP4A; inositol polyphosphate 4 phosphatase type I enzyme; LMB; leptomycin B; PtdIns(P); phosphatidyl inositol phosphate; Ins(1,4,5)P3; Inositol 1,4,5 tris-phosphate; PDK-1; phosphoinositide-dependent kinase-1; mTORC2; mammalian target of rapamycin compl

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

PTEN PDZ-binding domain suppresses mammary carcinogenesis in the MMTV-PyMT breast cancer model

Keywords: ژن PTEN; PTEN; PDZ-binding domain; Mammary tumor; Myoepithelial marker genes;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

ROS signalling in the biology of cancer

Keywords: ژن PTEN; AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells

Keywords: ژن PTEN; STX3; Breast cancer; PTEN; PI3K; Akt; mTOR;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells

Keywords: ژن PTEN; Adenosine receptors; Neuroregeneration; Glaucoma; Akt; 2-Cl-IB-MECA; IOP; intraocular pressure; RGC; retinal ganglion cell; NTG; normal tension glaucoma; AC; adenylyl cyclase; cAMP; cyclic adenosine monophosphate; PI3K; phosphoinositide 3-kinase; AdoR; ad

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Differential regulation of the pro-inflammatory biomarker, YKL-40/CHI3L1, by PTEN/Phosphoinositide 3-kinase and JAK2/STAT3 pathways in glioblastoma

Keywords: ژن PTEN; YKL-40; PTEN; PI3K; JAK2/STAT3; Transcriptomes;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Transcriptome analysis reveals novel insights into the response of low-dose benzo(a)pyrene exposure in male tilapia

Keywords: ژن PTEN; TGFi; TGF induced factor homeobox; TGF; transforming growth factor; IL1; interleukin 1; IL1i; IL1 inhibitors; IL1RL1; interleukin 1 receptor like 1; TNF; tumor necrosis factor; Nogo; reticulon 4 (RTN4/Nogo); NGF; nerve growth factor; STC; stanniocalcin 1;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR-γ and subsequent expression of HGF in colons

Keywords: ژن PTEN; Berberine; Pulmonary fibrosis; Gut; HGF; PPAR-γ; aP2; adipocyte fatty acid-binding protein 2; BMP-7; bone morphogenetic protein-7; BPV; a PTEN inhibitor; CD36; cluster of differentiation 36; ECM; extracellular matrix; EMSA; electrophoretic mobility shift

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Emerging paradigms in the treatment of liver metastases in colorectal cancer

Keywords: ژن PTEN; CRC; colorectal cancer; mCRC; metastatic colorectal cancer; CLM; colorectal liver metastases; SR; surgical resection; PVE; portal vein embolism; RFA; radiofrequency ablation; APC; adenomatous polyposis coli; LOH; loss of heterozygosity; EGFR; epidermal gr

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Deubiquitylating enzymes as cancer stem cell therapeutics

Keywords: ژن PTEN; Protein-IPSC; protein-induced pluripotent stem cells; CSCs; cancer stem cells; DUBs; deubiquitylating enzymes; ESCs; embryonic stem cells; PTMs; post-translational modifications; AML; acute myelogenous leukemia; USP/UBP; ubiquitin-specific processing prot

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136

Keywords: ژن PTEN; Akt; Cyclopentenone prostaglandins; 15-Deoxy-Δ12,14-prostaglandin J2; PTEN; Thiol modification;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Ampullary carcinoma-A genetic perspective

Keywords: ژن PTEN; AVC; ampulla of vater carcinoma; KRAS; Kirsten rat sarcoma viral oncogene homolog; OS; overall survival; RFS; recurrence free survival; HER2; human epidermal growth factor receptor 2; BRAF; B rapidly activated fibrosarcoma; BRCA2; breast cancer 2; TP53; t

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

The connexin 43 C-terminus: A tail of many tales

Keywords: ژن PTEN; Akt; protein kinase B; CCN; CYR61/connective tissue growth factor/nephroblastoma overexpressed; CDK1; cyclin-dependent kinase 1; CIP75; Cx43-interacting protein of 75 kDa; CIP85; Cx43-interacting protein of 85-kDa; CK1; casein kinase 1; Csk; C-terminal c

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes

Keywords: ژن PTEN; Cytomegalovirus; Monocytes; Small-molecule inhibitor; HCMV; human cytomegalovirus; h; hour; EGF; epidermal growth factor; EGFR; EGF receptor; αvβ3; alpha v beta 3 integrin; gB; glycoprotein B; gH; glycoprotein H; PI3K; phosphoinositide 3-kinase; PTEN; p

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons

Keywords: ژن PTEN; Aging; Motor cortex; Cortical pyramidal neurons; PTEN; mTOR; Animal;

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity and overweight on DNA stability: Few facts and many hypotheses

Keywords: ژن PTEN; AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib

Keywords: ژن PTEN; PTEN; Phosphatase and tensin homologue; PARP; poly(ADP-ribose) polymerase; PI3K; PI3 kinase; RPA1; replication protein A1; DSB; double-strand breaks; HR; homologous recombination; SSB; single strand breaks; γH2AX; Phospho-histone H2AX; PMSF; phenylmethyl

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Prevalence and Prognostic Significance of PTEN Loss in African-American and European-American Men Undergoing Radical Prostatectomy

Keywords: ژن PTEN; Prostatic carcinoma; PTEN; ERG; Race; African-American; European-American; Immunohistochemistry; Radical prostatectomy; Biomarker;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: Correlation with clinical outcomes

Keywords: ژن PTEN; Mutation; Lung cancer; Adenocarcinoma; EGFR; TP53; PIK3CA; PTEN; Kinase inhibitor; Erlotinib;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Original articleEvaluation of ERG and PTEN protein expression in cribriform architecture prostate carcinomas

Keywords: ژن PTEN; Intraductal carcinoma; Cribriform; ERG; PTEN; Kappa;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

miR-21 targets and inhibits tumor suppressor gene PTEN to promote prostate cancer cell proliferation and invasion: An experimental study

Keywords: ژن PTEN; Prostate cancer; miR-21; PTEN; Proliferation; Invasion;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Association of autoimmune thyroiditis and celiac disease with Juvenile Polyposis due to 10q23.1q23.31 deletion: Potential role of PI3K/Akt pathway dysregulation

Keywords: ژن PTEN; Autoimmune thyroiditis; Celiac disease; BMPR1A; PTEN; Juvenile Polyposis syndrome;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Comprehensive genomic profiling (CGP) of ovarian clear cell carcinomas (OCCC) identifies clinically relevant genomic alterations (CRGA) and targeted therapy options

Keywords: ژن PTEN; Ovarian clear cell carcinoma; PIK3CA; PTEN; Everolimus; Comprehensive genomic profiling;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

ESR1 single nucleotide polymorphism rs1062577 (c.*3804T > A) alters the susceptibility of breast cancer risk in Iranian population

Keywords: ژن PTEN; ATM; ataxia-telangiectasia mutated; BRCA1; BReast CAncer gene 1; BRCA2; BReast CAncer gene 2; CHECK2; checkpoint kinase 2; ER; estrogen receptor; ESR1; estrogen receptor 1; HER2; human epidermal growth factor 2; PR; progesterone receptor; PTEN; phosphatas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Lhermitte-Duclos disease: Clinical study with long-term follow-up in a single institution

Keywords: ژن PTEN; LDD; Lhermitte-Duclos disease; CS; Cowden Syndrome; PHTS; PTEN hamartoma tumor syndrome; PTEN; Phosphatase and tensin homolog; MRI; Magnetic resonance imaging; MRS; Magnetic resonance spectrophy; KPS; Karnofsky performance score; PTHC; Pseudotumoral hemic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Role for loss of nuclear PTEN in a harbinger of brain metastases

Keywords: ژن PTEN; Brain metastasis; PTEN; Subcellular localization; PDK1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Systemic PTEN-Akt1-mTOR pathway activity in patients with normal tension glaucoma and ocular hypertension: A case series

Keywords: ژن PTEN; Normal tension glaucoma; Ocular hypertension; PTEN; Akt1; 4EBP1; S6K; mTOR; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

NMR uncovers direct interaction between human NEDD4-1 and p34SEI−1

Keywords: ژن PTEN; PTEN; p34SEI−1; NEDD4-1; NMR (nuclear magnetic resonance);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The tumor suppressor phosphatase and tensin homolog protein (PTEN) is negatively regulated by NF-κb p50 homodimers and involves histone 3 methylation/deacetylation in UROtsa cells chronically exposed to monomethylarsonous acid

Keywords: ژن PTEN; Bladder cancer; Arsenic; NF-KB; PTEN; Inflammation; H3ac; H3K9me3; H3k27me3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical PaperClinicopathological parameters and prognostic relevance of miR-21 and PTEN expression in Wilms' tumor

Keywords: ژن PTEN; Wilms' tumor; miR-21; PTEN;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionPTEN loss and p27 loss differ among morphologic patterns of prostate cancer, including cribriform

Keywords: ژن PTEN; Gleason grading; Prostate cancer; PTEN; CDKN1B; p27; CD44;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Deregulated expression of miR-107 inhibits metastasis of PDAC through inhibition PI3K/Akt signaling via caveolin-1 and PTEN

Keywords: ژن PTEN; PDAC; miR-107; Caveolin-1; PTEN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

LncRNA GAS5 controls cardiac fibroblast activation and fibrosis by targeting miR-21 via PTEN/MMP-2 signaling pathway

Keywords: ژن PTEN; LncRNAs; long noncoding RNAs; GAS5; growth arrest-specific 5; miR-21; microRNA-21; AF; atrial fibrillation; MI; myocardial infarction; CFs; cardiac fibroblasts; ECM; extracellular matrix; Col1A1; type I collagen; α-SMA; smooth muscle alpha-action; PTEN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The impact of the IGF-1 system of cancer cells on radiation response - An in vitro study

Keywords: ژن PTEN; IGF-1R; insulin-like growth factor 1 receptor; SF; surviving fractions; IGF-1R/KR; kinase-deficient IGF-1R; Caco-2-KR4; IGF-1R/KR clone number 4; IRS-1; insulin receptor substrate 1; HRR; homologous recombination repair; NHEJ; non-homologous end joining;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original research articleImmunohistochemical analysis of PTEN, HER2/neu, and ki67 expression in patients with gastric cancer and their association with survival

Keywords: ژن PTEN; PTEN; phosphatase and tensin homolog; HER2; human epidermal growth factor receptor 2; OS; overall survival; DFS; disease free survival; TNM; tumor-node-metastasis; PIP3; phosphatidylinositol-(3,4,5)-triphosphate; TK; tyrosine kinase; EGFRs; epidermal grow

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers

Keywords: ژن PTEN; ADAM; a disintegrin and metalloproteinase; CHD1; chromodomain-helicase-DNA-binding protein 1; ERG; erythroblast transformation-specific (ETS) related gene; ETS; erythroblast transformation-specific; FISH; fluorescence in situ hybridization; FOXP1; forkhea

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Up-regulation of Biglycan is Associated with Poor Prognosis and PTEN Deletion in Patients with Prostate Cancer

Keywords: ژن PTEN; BGN; Biglycan; CHD1; Chromodomain-helicase-DNA-binding protein 1; ERCC1; Excision repair cross-complementation; ERG; Erythroblast transformation-specific (ETS) related gene; FISH; Fluorescence in situ hybridization; FOXP1; Fork head box protein P1; Ki67LI

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

miR-367 regulation of DOC-2/DAB2 interactive protein promotes proliferation, migration and invasion of osteosarcoma cells

Keywords: ژن PTEN; miRNAs; microRNAs; OS; osteosarcoma; EMT; epithelial-to-mesenchymal transition; ESCC; esophageal squamous carcinoma; FBXW7; F-box and WD repeat domain-containing 7; NSCLC; non-small cell lung cancer; HCC; hepatocellular carcinoma; PTEN; phosphatase and te

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway

Keywords: ژن PTEN; ADR; adriamycin; miRNA; microRNA; UTR; untranslated region; PTEN; phosphatase a tensin homolog deleted on chromosome 10; PIP3; phosphatidylinositol-3,4,5-triphosphate; PIP2; diphosphate product; IC50; the inhibitory concentration to produce 50% cell death

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ResearchSafety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study

Keywords: ژن PTEN; LY2780301; Gemcitabine; PI3K/AKT/mTOR pathway; Dual p70S6K/AKT inhibition; PTEN; Molecular alterations; Phase I; Molecular screening; Drug development;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه