Effect of PDGF-Rb antagonist imatinib on endometrial injury repairing in mouse model
Keywords: بروموداکسی اوریدین; PDGF-Rb; Endometrium; Imatinib mesylate; BrdU; MVD
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Long-term tracing of the BrdU label-retaining cells in adult rat brain
Keywords: بروموداکسی اوریدین; BrdU; 5-bromo-2â²-deoxyuridine; BSA; bovine serum albumin; DAB; 3,3â²-diaminobenzidine; DAPI; 4â²,6-diamidino-2-phenylindole; DG; dentate gyrus; GFAP; glial fibrillary acidic protein; HRP; horseradish peroxidase; LRCs; Label-retaining cells; LV; latera
Peroral administration of 5-bromo-2-deoxyuridine in drinking water is not a reliable method for labeling proliferating S-phase cells in rats
Keywords: بروموداکسی اوریدین; 5-bromo-2′-deoxyuridine; BrdU; Peroral administration; Pharmacokinetic; Rat
Design and characterization of a composite material based on Sr(II)-loaded clay nanotubes included within a biopolymer matrix
Keywords: بروموداکسی اوریدین; HNT; Halloysite nanotubes; PHBV; 3-polyhydroxybutyrate-co-3-hydroxyvalerate; HNT-Sr; Halloysite nanotubes loaded with Sr2+; HNT-PHBV; nanocomposite material made of Halloysite nanotubes and 3-polyhydroxybutyrate-co-3-hydroxyvalerate; HNT-Sr-PHBV; nanoco
Chronic P7C3 treatment restores hippocampal neurogenesis
Keywords: بروموداکسی اوریدین; Dentate gyrus; Doublecortin; BrdU; Neuronal survival; Ki67; AC3;
Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 mice
Keywords: بروموداکسی اوریدین; AD; Alzheimer's disease; Aβ; amyloid-β peptide; ANOVA; one-way analysis of variance; APP; amyloid-β precursor protein; BCA; bicinchoninic acid; BrdU; 5-bromo-2-deoxyuridine; DG; dentate gyrus; ELISA; enzyme-linked immunosorbent assay; NeuN; neuron-sp
Interleukin 18 augments growth ability via NF-κB and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyuridine; IL-18; interleukin 18; IL-18R; interleukin 18 receptor; rrIL-18; recombinant rat interleukin 18; RT-PCR; real-time polymerase chain reaction; siRNA; short interference RNA; NC; negative control; MTT; methyl thiazolyl tetrazolium;
Mucosal vaccination by the intranasal route. Nose-associated lymphoid tissue (NALT)-Structure, function and species differences
Keywords: بروموداکسی اوریدین; BrdU; Bromodesoxy Uridine; CV; conventional; DC; dendritic cell; GF; germ free; HEV; high endothelial venule; MAdCAM-I; mucosal adhesion molecule; MALT; mucosa-associated lymphoid tissue; M cell; microfold cell; NALT; nose-associated lymphoid tissue; PNAd
Downregulation of PEA-15 reverses G1 arrest, and nuclear and chromatin changes of senescence phenotype via pErk1/2 translocation to nuclei
Keywords: بروموداکسی اوریدین; HDF; human diploid fibroblasts; TPA; 12-O-tetradecanoylphorbol-13-acetate; SA-pErk1/2; senescence associated phospho-extracellular signal-regulated protein kinase 1/2; BrdU; 5-bromo-2â²-deoxyuridine; PML; promyelocytic leukemia; 53BP1; p53-binding protei
FGL-functionalized self-assembling nanofiber hydrogel as a scaffold for spinal cord-derived neural stem cells
Keywords: بروموداکسی اوریدین; RADA16; AcN-RADARADARADARADA-CONH2; FGL; AcN-EVYVVAENQQGKSKA-CONH2; RADA16-FGL; AcN-RADARADARADARADAGGEVYVVAENQQGKSKA-CONH2; FGLmx; the mixed solution of RADA16 and RADA16-FGL solution; AFM; atomic force microscopy; CD; circular dichroism; SC-NSCs; spinal
Oxygen regulates proliferation of neural stem cells through Wnt/β-catenin signalling
Keywords: بروموداکسی اوریدین; ARNT; aryl hydrocarbon receptor nuclear translocator; BrdU; 5-bromo-2â²-deoxyuridine; GFAP; glial fibrillary acidic protein; Hif; hypoxia-inducible factor; IWP; inhibitor of Wnt production; IWR; inhibitor of Wnt response; Map2; microtubule-associated pro
Growth arrest in the ribosomopathy, Bowen-Conradi syndrome, is due to dramatically reduced cell proliferation and a defect in mitotic progression
Keywords: بروموداکسی اوریدین; BCS; Bowen-Conradi syndrome; EMG1; Essential for Mitotic Growth 1; ES; embryonic stem; MEFs; mouse embryonic fibroblasts; BrdU; bromodeoxyuridine; E; embryonic day; Ribosomopathy; Bowen-Conradi syndrome; Intrauterine growth retardation; Proliferation;
Robust increase of microglia proliferation in the fornix of hippocampal axonal pathway after a single LPS stimulation
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyuridine; IFN-γ; interferon-γ; IL-1β; interleukin-1β; LPS; lipopolysaccharide; LSD; dorsal part of lateral septal nucleus; NPCs; neural progenitor cells; PBS; phosphate-buffered saline; PBST; PBS containing 0.3% Triton X-100; PFA; paraf
Fingolimod treatment promotes proliferation and differentiation of oligodendrocyte progenitor cells in mice with experimental autoimmune encephalomyelitis
Keywords: بروموداکسی اوریدین; MS; multiple sclerosis; CNS; central nervous system; S1P; sphingosine 1-phosphate; BBB; blood-brain barrier; OPC; oligodendrocyte progenitor cell; Shh; sonic hedgehog; Smo; smoothened; EAE; experimental autoimmune encephalomyelitis; PLP; myelin proteoli
Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade
Keywords: بروموداکسی اوریدین; IR; insulin receptor; IGFR; insulin-like growth factor receptor; IRS-1; insulin receptor substrate-1; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of rapamycin; Grb2; growth factor receptor-bound protein 2; FGF2; fibroblast growth factor 2; DTP
Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis
Keywords: بروموداکسی اوریدین; PHD; prolyl-4 hydroxylase domain; LAD; left anterior descending; I/R; ischemia-reperfusion; HIF; hypoxia inducible factor; DDR; DNA damage response; MI; myocardial infarction; AAR; area at risk; TTC; triphenyl tetrazolium chloride; ATM; ataxia telangiec
BMSCs transplantation improves cognitive impairment via up-regulation of hippocampal GABAergic system in a rat model of chronic cerebral hypoperfusion
Keywords: بروموداکسی اوریدین; AD; Alzheimer's diseases; ANOVA; analysis of variance; BMSCs; bone marrow mesenchymal stem cells; BrdU; bromo-2-deoxy uridine; EDTA; ethylenediaminetetraacetic acid; GABA; gamma amino butyric acid; GABABR1; GABAB receptor 1; GAD; glutamic acid decarboxy
Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases
Keywords: بروموداکسی اوریدین; aNPC; adult neural precursor cells; SGZ; subgranular zone; DG; dentate gyrus; JNK; c-Jun NH2-terminal kinase; MAP; mitogen activated protein; DMSO; dimethyl sulfoxide; BrdU; 5-bromo-2â²-deoxyuridine; EGF; epidermal growth factor; bFGF; basic fibroblast g
Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyurinine; DCX; doublecortin; DG; dentate gyrus; GFAP; glial fibrillary acidic protein; IL-1β; interleukin-1β; LPS; lipopolysaccharide; LTP; long-term potentiation; TLR4; toll-like receptor-4; TNFα; tumor necrosis factor-alpha; Pb; plumbu
Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyuridine; CADASIL; cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; E; embryonic day; DG; dentate gyrus; DCX; doublecortin; GFAP; glial fibrillaric acid protein; GOM; granular osmiophilic material;
Severe instead of mild hyperglycemia inhibits neurogenesis in the subventricular zone of adult rats after transient focal cerebral ischemia
Keywords: بروموداکسی اوریدین; ATP; adenosine triphosphate; BDNF; brain-derived neurotrophic factor; BrdU; 5â²-bromo-2â²-deoxyuridine; CREB; cyclic-AMP response element-binding protein; DCX; doublecortin; DG; dentate gyrus; ECA; external carotid artery; EDTA; ethylenediaminetetraacet
N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy
Keywords: بروموداکسی اوریدین; Prostate cancer; Androgen signaling; Taxanes; Therapeutic resistance; Epithelial-mesenchymal transition; ADT; androgen deprivation therapy; AR; androgen receptor; AR-V; androgen receptor splice variant; CRPC; castration-resistant prostate cancer; DHT; dih
PEDF counteracts DL-α-aminoadipate toxicity and rescues gliotoxic damages in RPE-free chicken retinal explants
Keywords: بروموداکسی اوریدین; Gliosis; Inner plexiform layer; IPL subband; Müller glial cell; Photoreceptor; Radial glia; AAA; DL-α-aminoadipate; AC; amacrine cell; ACh; acetylcholine; AChE; acetylcholinesterase; BDNF; brain-derived neurotrophic factor; BrdU; bromo-deoxyuridine; CER
Research ReportInvolvement of caspase-3/PTEN signaling pathway in isoflurane-induced decrease of self-renewal capacity of hippocampal neural precursor cells
Keywords: بروموداکسی اوریدین; BrdU; 5׳-Bromo-2-deoxyuridine; C-C3; cleaved (active); DAPI, 4׳; ,6-diamidino-2-phenylindole; DG; dentate gyrus; GFAP; glial fibrillary acidic protein; ISO; isoflurane; LDH; lactate dehydrogenase; NPC; neural precursor cells; P1; postnatal day 1; PTEN;
Peptide fragment of thymosin β4 increases hippocampal neurogenesis and facilitates spatial memory
Keywords: بروموداکسی اوریدین; Ac-SDKP; N-acetyl-serylaspartyl-lysyl-proline; ANOVA; one-way analysis of variance; BrdU; 5-bromo-2â²-deoxyuridine; DCX; doublecortin; DG; dentate gyrus; GFAP; glial fibrillary acidic protein; GSK-3β; glycogen synthase kinase-3β; NeuN; neuronal nuclei;
In vivo effects of bumetanide at brain concentrations incompatible with NKCC1 inhibition on newborn DGC structure and spontaneous EEG seizures following hypoxia-induced neonatal seizures
Keywords: بروموداکسی اوریدین; ANOVA; analysis of variance; BBB; blood-brain barrier; BrdU; bromodeoxyuridine; CB; control + bumetanide; CNS; central nerve system; CRH; corticotrophin releasing hormone; DCX; doublecortin; DG; dentate gyrus; DGCs; dentate gyrus cells; EEG; electroen
A natural diarylheptanoid promotes neuronal differentiation via activating ERK and PI3K-Akt dependent pathways
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyuridine; DG; dentate gyrus; DIV; day in vitro; ERK; extracellular signal-regulated kinase; JNK; c-Jun NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinase; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetr
Prenatal exposure to ethanol stimulates hypothalamic CCR2 chemokine receptor system: Possible relation to increased density of orexigenic peptide neurons and ethanol drinking in adolescent offspring
Keywords: بروموداکسی اوریدین; BEC; blood ethanol concentration; BrdU; 5-bromo-2-deoxyuridine; E10; embryonic day 10; IF; immunofluorescence histochemistry; LH; lateral hypothalamus; MCH; melanin-concentrating hormone; OX; orexin; prenatal ethanol; lateral hypothalamus; melanin-concent
Treatment with UDP-glucose, GDNF, and memantine promotes SVZ and white matter self-repair by endogenous glial progenitor cells in neonatal rats with ischemic PVL
Keywords: بروموداکسی اوریدین; BrdU; 5-bromodeoxyuridine; CNPase; 2â²,3â²-cyclic-nucleotide 3â²-phosphodiesterase; GDNF; glial cell line-derived neurotrophic factor; GPR17; G protein-coupled receptor 17; MBP; myelin basic protein; Mem; memantine; NG2; neuron glial antigen 2; NMDA; N
Stem cell factor and granulocyte colony-stimulating factor exhibit therapeutic effects in a mouse model of CADASIL
Keywords: بروموداکسی اوریدین; CADASIL; cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalophy; SCF; stem cell factor; G-CSF; granulocyte colony-stimulating factor; CAA; cerebral amyloid angiopathy; SVZ; the subventricular zone; BrdU; bromodeoxyuridine
Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyuridine; AdNox4; adenoviral Nox4; AdβGal; adenoviral β-galactosidase; PEG; polyethylene glycol; Wt; wild type; Tg; transgenic; NRC; neonatal rat cardiomyocyte; Cardiomyocyte proliferation; ERK1/2; Nox4; Cyclin D2; Redox signalling; c-Myc
Research reportThe effects of chronic fluoxetine treatment following injury of medial frontal cortex in mice
Keywords: بروموداکسی اوریدین; BrdU; 5-bromo-2â²-deoxyuridine; dH2O; distilled water; EPM; elevated plus maze; GCL; granule cell layer; MFC; medial frontal cortex; MWT; Morris water task; NeuN; neuronal nuclei; PBS; phosphate buffered saline; PFA; paraformaldehyde; SSRI; selective ser
Growth Factor Independence-1 (Gfi1) Is Required for Pancreatic Acinar Unit Formation and Centroacinar Cell Differentiation
Keywords: بروموداکسی اوریدین; Centroacinar Cells; Claudin 10; Growth Factor Independence-1 (Gfi1); BPL; Bauhinia purpurea lectin; BrdU; bromodeoxyuridine; CACs; centroacinar cells; DIG; digoxigenin; EM; electron micrographs; Gfi1; growth factor independence-1; PBS; phosphate-buffered
Stromal Indian Hedgehog Signaling Is Required for Intestinal Adenoma Formation in Mice
Keywords: بروموداکسی اوریدین; COX2; Prostaglandin; Mouse Model; Colon Cancer; α-Sma Sma; α-Sma smooth muscle actin; Bmp; bone morphogenetic protein; BrdU; bromodeoxyuridine; Cyp1a1Cre; cytochrome p450-1a1Cre; Gli1; glioma-associated oncogene; Hhip; Hedgehog-interacting protein; Ihh;
ReviewSleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function
Keywords: بروموداکسی اوریدین; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived neurotrophic factor; BrdU; 5-bromo-2â²-deoxyuridine; cAMP; cyclic adenosine monophosphate; CPT; 8-cyclopentyl-1,3-di
TIPIN depletion leads to apoptosis in breast cancer cells
Keywords: بروموداکسی اوریدین; Apoptosis; Basal-like; Replicative stress; Therapeutic target; TIPIN; Triple-negative breast cancer; 2D; 2-dimensional; 3D; 3-dimensional; BC; breast cancer; BrdU; 5-bromo-2â²-deoxyuridine; CldU; 5-chloro-2â²-deoxyuridine; CN; copy number; DSBs; DNA dou
Immunomodulatory and cytotoxic effects of Nigella sativa and thymoquinone on rat splenocytes
Keywords: بروموداکسی اوریدین; Nigella sativa; Th1/Th2 balance; Thymoquinone; Splenocytes; N. sativa; Nigella sativa; TQ; thymoquinone; IL-4; interleukin 4; IFN-γ; interferon-γ; PHA; phytohemagglutinin; Con A; concavaline A; MNCs; mononuclear cells; OVA; ovalbumin; CC-5; ethyl acetat
Downregulation of survivin regulates adult hippocampal neurogenesis and apoptosis, and inhibits spatial learning and memory following traumatic brain injury
Keywords: بروموداکسی اوریدین; ANOVA; analysis of variance; BrdU; 5â²-bromo-2â²-deoxyuridine; DAPI; 4â²,6-diamidino-2-phenylindole; DCX; doublecortin; DG; dentate gyrus; EL; escape latency; IAP; inhibitor of apoptosis protein; LFP; lateral fluid percussion; MWM; Morris water maze; N
Gestational marginal zinc deficiency impaired fetal neural progenitor cell proliferation by disrupting the ERK1/2 signaling pathway
Keywords: بروموداکسی اوریدین; ERK1/2; extracellular signal-regulated kinases 1/2; NPC; neural progenitor cell; E; embryonic day; MEK1/2; mitogen-activated ERK1/2 kinases 1/2; PP2A; protein phosphatase 2A; NGF; nerve growth factor; BDNF; brain-derived neurotrophic factor; BrdU; bromode
Central acylated ghrelin improves memory function and hippocampal AMPK activation and partly reverses the impairment of energy and glucose metabolism in rats infused with β-amyloid
Keywords: بروموداکسی اوریدین; GOAT; ghrelin O-acyltransferase; GHSR; growth hormone secretagogue receptor; LV; lateral ventricle; ICV; intracerebroventricular; AD-G; Acyl-ghrelin ICV infusion; AD-DES-G; Des-acyl-ghrelin ICV infusion; AD-C; phosphate buffered saline ICV infusion; Non-A
Disruption of the mevalonate pathway induces dNTP depletion and DNA damage
Keywords: بروموداکسی اوریدین; ACN; acetonitrile; BrdU; 5-bromo-2â²-deoxyuridine; DMAPP; dimethylallyl diphosphate; dNs; deoxyribonucleosides; dNTP; deoxyribonucleoside triphosphate; E2F; E2 transcription factor; Fmev; 6-fluoromevalonate; IPP; isopentenyl diphosphate; HU; hydroxyurea;
Litchi chinensis: medicinal uses, phytochemistry, and pharmacology
Keywords: بروموداکسی اوریدین; Aq; aqueous; A549; human lung cancer; ABTS; 2,2â²-Azinobis(3-ethylbenzothiazoline-6-sulfonate); ADP; adenosine diphosphate; AGS; human gastric epithelial; ADPRTL1; ADP-ribosyltransferase (NAD+poly (ADP-ribose) polymerase)-like 1); ADAM9; metalloproteinas
Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo
Keywords: بروموداکسی اوریدین; IGF- 1; Black pigmentation; Cell proliferation; BrdU; TGF-β1; Wild-type mouse
Bromodeoxyuridine (BrdU) treatment to measure hepatocellular proliferation does not mask furan-induced gene expression changes in mouse liver
Keywords: بروموداکسی اوریدین; BrdU; bromodeoxyuridine; IHC; immunohistochemistry; IPA; ingenuity pathway analysis; MOA; mode of action; PUR; predicted upstream regulator; Bromodeoxyuridine (BrdU); Gene expression; Toxicogenomics; Furan;
The Notch γ-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-β/Smad2/3 signaling pathway activation
Keywords: بروموداکسی اوریدین; Kidney fibrosis; Epithelial-to-mesenchymal transition; Fibroblast; Notch; TGF-β; DBZ; dibenzazepine; UUO; unilateral ureteral obstruction; NICD; Notch intracellular domain; ICN; intracellular domain of Notch; TECs; tubular epithelial cells; ECM; extracel
Rosmarinic acid ameliorates PTSD-like symptoms in a rat model and promotes cell proliferation in the hippocampus
Keywords: بروموداکسی اوریدین; PTSD; post-traumatic stress disorder; ESPS; enhanced single prolonged stress; RA; rosmarinic acid; p-ERK1/2; phosphorylation extracellular regulated protein kinases; BrdU; bromodeoxyuridine; Allo; allopregnanolone; Hippocampus; Post-traumatic stress disor
Automatic counting and positioning of 5-bromo-2-deoxyuridine (BrdU) positive cells in cortical layers of rat brain slices
Keywords: بروموداکسی اوریدین; Histopathology; Image analysis; Immunohistochemistry; Cortical development; BrdU; Automated evaluation
Tissue-type plasminogen activator is not necessary for platelet-derived growth factor-c activation
Keywords: بروموداکسی اوریدین; PDGF; platelet-derived growth factor; tPA; tissue-type plasminogen activator; Tg; transgenic; KO; knock-out; uPA; urokinase plasminogen activator; ECM; extracellular matrix; PAI-1; plasminogen activator inhibitor-1; IP; intraperitoneally; CUB; complement
Research ArticleAMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression
Keywords: بروموداکسی اوریدین; AMPK; AMP-activated protein kinase; BrdU; Bromodeoxyuridine; CaMKK; Calmodulin dependent protein Kinase Kinase; CRE; cAMP Response Element; EGF; Epidermal Growth Factor; HGF; Hepatocyte Growth Factor; HuR; Human-antigen R; IL-6; Interleukin-6; KO; Knock-O
NANOS2 promotes male germ cell development independent of meiosis suppression
Keywords: بروموداکسی اوریدین; 5-bromo-2â²-deoxyuridine; BrdU; double knockout; dKO; embryonic day; E; immunoprecipitation; IP; retinoic acid; RA; reverse transcription; RT; phosphate-buffered saline; PBS; polymerase chain reaction; PCR; primordial germ cell; PGC; RNA immunoprecipitat