The expression of fgfr3 in the zebrafish head
Keywords: استخوان‌کاه ; fgfr3; Zebrafish; Chondrocyte; Osteoblast; Bone cranium; Cartilage; Chondroclasts; Osteoclasts;
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Analysis of two transcript isoforms of vacuolar ATPase subunit H in mouse and zebrafish
Keywords: استخوان‌کاه ; V-ATPase; vacuolar ATPase; ATP6V1H; subunit H of vacuolar ATPase; SFD; sub fifty-eight-kDa dimer, or doublet; V-ATPase; Osteoclasts; ATP6V1H; Isoform; Alternative splicing; Zebrafish;
Engineered exosomes: A new promise for the management of musculoskeletal diseases
Keywords: استخوان‌کاه ; Engineered exosomes; Drug delivery; Musculoskeletal diseases; Regenerative medicine; Oncology; Immune system regulation; 3â²UTR; 3â²untranslated regions; 6-OHDA; 6-hydroxydopamine; APC; adenomatous polyposis coli; BRD7; bromo-domain-containing protein 7
Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis
Keywords: استخوان‌کاه ; Prostate cancer bone metastasis; Osteoblasts; Osteoclasts; TGF-β signaling; TGF-β type II receptor (TGFBR2); bFGF;
BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway
Keywords: استخوان‌کاه ; BCAP; B-cell adaptor for PI3K; PI3K; phosphatidylinositol 3-Kinase; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear
Siglec-15-targeting therapy increases bone mass in rats without impairing skeletal growth
Keywords: استخوان‌کاه ; Siglec-15; Anti-Siglec-15 Ab; Juvenile osteoporosis; Osteoclasts; Growth plate;
Ferulic acid, a dietary polyphenol suppresses osteoclast differentiation and bone erosion via the inhibition of RANKL dependent NF-κB signalling pathway
Keywords: استخوان‌کاه ; Ferulic acid; Osteoclasts; RANKL; NF-κB; Bone erosion;
Selective inhibition of Src family kinases by SU6656 increases bone mass by uncoupling bone formation from resorption in mice
Keywords: استخوان‌کاه ; Src family kinases; SU6656; Osteoclasts; Osteoblasts; Bone formation; BMP signaling;
RANKL, Ephrin-Eph and Wnt10b are key intercellular communication molecules regulating bone remodeling in autologous transplanted goldfish scales
Keywords: استخوان‌کاه ; RANKL; receptor activator of NF-κB ligand; RANK; receptor activator of nuclear factor κB; TRAP; tartrate-resistant acid phosphatase; NFATC1; Nuclear factor of activated T cells C1; CTSK; cathepsin K; OC-Stamp; osteoclast stimulatory transmembrane protei
Original articleEffects of fenoterol on the skeletal system depend on the androgen level
Keywords: استخوان‌کاه ; Fenoterol; Androgens; Bone; Osteoblasts; Osteoclasts;
Full Length ArticleIn vitro osteoclastogenesis from Gaucher patients' cells correlates with bone mineral density but not with Chitotriosidase
Keywords: استخوان‌کاه ; Gaucher disease; Bone pathology; Osteoclasts; Chitotriosidase; Bone mineral density;
Pilose antler peptide potentiates osteoblast differentiation and inhibits osteoclastogenesis via manipulating the NF-κB pathway
Keywords: استخوان‌کاه ; Pilose antler peptide; Inflammation; Osteoblasts; Osteoclasts; NF-κB;
General reviewBasic research and clinical application of beta-tricalcium phosphate (β-TCP)Recherche fondamentale et application clinique du bêta-tricalcium phosphate (β-TCP)
Keywords: استخوان‌کاه ; Bone substitute; β-TCP; Bone formation; Osteoclasts; Coupling; Substituts osseux; β-TCP; Formation osseuse; Ostéoclastes; Couplage;
Sciadopitysin suppresses RANKL-mediated osteoclastogenesis and prevents bone loss in LPS-treated mice
Keywords: استخوان‌کاه ; Osteoclasts; Bone resorption; NFATc1; Bone loss; NF-κB; RANKL;
Water extract of Uncaria sinensis suppresses RANKL-induced bone loss by attenuating osteoclast differentiation and bone resorption
Keywords: استخوان‌کاه ; Uncaria sinensis; Osteoclasts; Receptor activator for nuclear factor-κB ligand; Nuclear factor of activated T-cells; Cytoplasmic 1;
Neohesperidin suppresses osteoclast differentiation, bone resorption and ovariectomised-induced osteoporosis in mice
Keywords: استخوان‌کاه ; Neohesperidin; Osteoclasts; Osteoporosis; Inhibition;
Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance bone formation of osteoblasts and decrease bone resorption of osteoclasts
Keywords: استخوان‌کاه ; Psoralidin; Coumestrol; Isopentenyl group; Osteoblasts; Osteoclasts;
Pathogenic conversion of regulatory B10 cells into osteoclast-priming cells in rheumatoid arthritis
Keywords: استخوان‌کاه ; Rheumatoid arthritis; Regulatory B10 cells; Osteoclasts; RANKL; RA; rheumatoid arthritis; RANKL; receptor activator of NF-κB ligand; OPG; osteoprotegerin; TNF; tumor necrosis factor; AIDs; autoimmune diseases; PB; peripheral blood; SF; synovial fluid; CI
Swertiamarin, a natural steroid, prevent bone erosion by modulating RANKL/RANK/OPG signaling
Keywords: استخوان‌کاه ; Bone erosion; Osteoclastogenesis; Swertiamarin; Adjuvant induced animals; Osteoblasts; Osteoclasts;
Full length articleOsteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates
Keywords: استخوان‌کاه ; Osteoclasts; Hydroxyapatite; Differentiation; Topography; Ionic exchange; Bone resorption;
Microfluidic co-culture platform for investigating osteocyte-osteoclast signalling during fluid shear stress mechanostimulation
Keywords: استخوان‌کاه ; Mechanobiology; Fluid flow shear stress; Microfluidic; Osteocytes; Osteoclasts; Co-culture;
Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro
Keywords: استخوان‌کاه ; Gastrodin; Osteoclasts; Differentiation; NFATc1; Osseointegration;
Osteoclastogenic capacity of peripheral blood mononuclear cells is not different between women with and without osteoporosis
Keywords: استخوان‌کاه ; Osteoclasts; Peripheral blood mononuclear cells; Deoxypyridinoline; Osteoporosis; Fractures;
Characterization and osteogenic activity of SrTiO3/TiO2 nanotube heterostructures on microporous titanium
Keywords: استخوان‌کاه ; Micro-/nano structuralization; SrTiO3/TiO2 heterostructures; Protein adsorption; Osteoblasts; Osteoclasts;
Sphingosine 1-phosphate (S1P) signalling: Role in bone biology and potential therapeutic target for bone repair
Keywords: استخوان‌کاه ; Bone regeneration; Bone defect; Osteoblasts; Osteoclasts; Sphingosine 1-phosphate;
Hif1α is required for osteoclast activation and bone loss in male osteoporosis
Keywords: استخوان‌کاه ; Testosterone; Osteoporosis; Hif1α; Male; Osteoclasts; Bone;
Semaphorin-3a, neuropilin-1 and plexin-A1 in prosthetic-particle induced bone loss
Keywords: استخوان‌کاه ; Osteoclasts; Peri-prosthetic osteolysis; Semaphorin-3a; Neuropilin-1; Plexin-A1
P62: An emerging oncotarget for osteolytic metastasis
Keywords: استخوان‌کاه ; P62/SQSTM1; Bone metastasis; Cancer; Osteoclasts; Autophagy
Sex-related differences in the skeletal phenotype of aged vitamin D receptor global knockout mice
Keywords: استخوان‌کاه ; Vitamin D receptor; 1,25-Dihydroxyvitamin D3; Osteoblasts; Osteoclasts; Bone remodelling;
Salubrinal improves mechanical properties of the femur in osteogenesis imperfecta mice
Keywords: استخوان‌کاه ; Salubrinal; Osteogenesis imperfecta; Osteoclasts; Bone marrow derived cells; Mechanical test;
Melatonin, bone regulation and the ubiquitin-proteasome connection: A review
Keywords: استخوان‌کاه ; Melatonin (PubChem CID: 896); Bortezomib (PubChem CID: 387447); Lactacystin (PubChem CID: 6610292); Osteoblasts; Osteoclasts; Parathyroid hormone; Rankl; SCFB-TrCP; Bortezomib;
Rictor/mTORC2 loss in osteoblasts impairs bone mass and strength
Keywords: استخوان‌کاه ; Rictor; mTORC2; Osteoblasts; Osteoclasts; Bone remodeling;
Identifying Patient-Specific Pathology in Osteoarthritis Development Based on MicroCT Analysis of Subchondral Trabecular Bone
Keywords: استخوان‌کاه ; osteoarthritis; subchondral bone; microCT; osteoclasts; VEGF;
Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development
Keywords: استخوان‌کاه ; Efn, ephrin; Osx, osterix; fl, floxed; MSC, mesenchymal stem cells; HSC, hematopoietic stem cellsEph/ephrin; Osterix; Endochondral ossification; Osteoprogenitors; Osteoclasts; Chondrocytes
Combination therapy with BMP-2 and a systemic RANKL inhibitor enhances bone healing in a mouse critical-sized femoral defect
Keywords: استخوان‌کاه ; Bone healing; BMP; Antiresorptives; Osteoclasts; Bone histomorphometry;
Establishment of a 3D-dynamic osteoblasts–osteoclasts co-culture model to simulate the jawbone microenvironment in vitro
Keywords: استخوان‌کاه ; 3D cell co-culture; MRONJ; Osteoblasts; Osteoclasts
Dietary compound gossypetin inhibits bone resorption through down-regulating lysosomal cathepsin K activity and autophagy-related protein induction in actin ring-bearing osteoclasts
Keywords: استخوان‌کاه ; Autophagy-related protein; Bone resorption; Gossypetin; Lacunar acidification; Osteoclasts; Ruffled borderAe2, anion exchange protein 2; Atg, autophagy-related protein; CAII, carbonic anhydrase II; ClC-7, chloride ion channel 7; LC3, microtubule-associate
The effect of bisphosphonate treatment on osteoclast precursor cells in postmenopausal osteoporosis: The TRIO study
Keywords: استخوان‌کاه ; Bisphosphonates; Osteoporosis; Osteoclasts; Osteoclast precursor cells;
Arthritogenic T cells in autoimmune arthritis
Keywords: استخوان‌کاه ; Rheumatoid arthritis; Regulatory T cells; Th17 cells; Synovial fibroblasts; Osteoclasts;
Inferences from genetically modified mouse models on the skeletal actions of vitamin D
Keywords: استخوان‌کاه ; Vitamin D; Bone; Osteoblast; Osteocytes; Osteoclasts; 1,25-Dihydroxyvitamin D; 1α-Hydroxylase; Cyp27b1; Vitamin D receptor; Targeted deletion; Genetic mouse models; Extra-skeletal effects;
Cathepsin K Inhibitor Regulates Inflammation and Bone Destruction in Experimentally Induced Rat Periapical Lesions
Keywords: استخوان‌کاه ; Cathepsin K inhibitor; major histocompatibility complex class II molecules; osteoclasts; periapical bone destruction; periapical lesions; proinflammatory cytokines
Bropirimine inhibits osteoclast differentiation through production of interferon-β
Keywords: استخوان‌کاه ; Osteoclasts; Differentiation; Toll-like receptor-7; Interferon-β
Involvement of PU.1 in NFATc1 promoter function in osteoclast development
Keywords: استخوان‌کاه ; NFATc1; Osteoclasts; Promoter; PU.1; Transcription factorBM, bone marrow; ChIP, chromatin immunoprecipitation; DC, dendritic cells; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; TRAP, tartrate resistant acid phosphatase
External Cervical Resorption Associated with the Use of Bisphosphonates: A Case Series
Keywords: استخوان‌کاه ; Bisphosphonates; cone-beam computed tomographic imaging; etiology; external cervical resorption; osteoclasts; osteonecrosis of the jaw; proinflammatory cytokines
ST2 Deletion Increases Inflammatory Bone Destruction in Experimentally Induced Periapical Lesions in Mice
Keywords: استخوان‌کاه ; Bone loss; inflammation; osteoclasts; periapical lesions; RANKL; ST2; Th1/Th17 cells
Bioaggregate Inhibits Osteoclast Differentiation, Fusion, and Bone Resorption In Vitro
Keywords: استخوان‌کاه ; Bioaggregate; bone resorption; calcium silicate bioceramic; osteoclastogenesis; osteoclasts; RAW264.7
Tenuigenin inhibits RANKL-induced osteoclastogenesis by down-regulating NF-κB activation and suppresses bone loss in vivo
Keywords: استخوان‌کاه ; Tenuigenin; Osteoclasts; Osteolysis; RANKL; NF-κB;
Ewing's sarcoma of bone tumor cells produces MCSF that stimulates monocyte proliferation in a novel mouse model of Ewing's sarcoma of bone
Keywords: استخوان‌کاه ; Ewing's sarcoma; Osteoblasts; Monocytes; Osteoclasts; Bone growth; MCSF;
Synthesis and biological evaluation of aminomethylidenebisphosphonic derivatives of β-arylethylamines
Keywords: استخوان‌کاه ; Bisphosphonates; Bisphosphonic acids; Arylethylamines; Isocyanides; Isonitriles; Osteoclasts;
An adult osteopetrosis model in medaka reveals the importance of osteoclast function for bone remodeling in teleost fish
Keywords: استخوان‌کاه ; Osteoclasts; Osteoblasts; Vertebra; Vertebral centra; Vertebral arch; Cathepsin K; Osteoporosis; Osteopetrosis