The Coxib case: Are EP receptors really guilty?
Keywords: پروستاگلاندینها; Coxib; NSAIDs; Prostaglandin; EP receptor; Platelet;
مقالات ISI پروستاگلاندینها (ترجمه نشده)
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Sex differences in angiotensin II responses contribute to a differential regulation of cox-mediated vascular dysfunction during aging
Keywords: پروستاگلاندینها; Vascular aging; Sex-differences; Renin-angiotensin system; Prostaglandin; Endothelial dysfunction;
Alterations in eicosanoid composition during embryonic development in the chorioallantoic membrane of the American alligator (Alligator mississippiensis) and domestic chicken (Gallus gallus)
Keywords: پروستاگلاندینها; American alligator; Eicosanoid; Prostaglandin; Chorioallantoic membrane; Oviparous; Amniotes; Cyclooxygenase;
Phylogenetic characterization of Clonorchis sinensis proteins homologous to the sigma-class glutathione transferase and their differential expression profiles
Keywords: پروستاگلاندینها; C-H2O2; cumene hydroperoxide; CDS; coding DNA sequence; ESP; excretory-secretory products; GSH; reduced glutathione; GST; glutathione transferase; I-3-C; indole-3-carbinol; MAPEG; membrane-associated proteins in eicosanoid and glutathione metabolism; PB;
Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3
Keywords: پروستاگلاندینها; Mast cells; prostaglandin E2; leukotriene D4; CysLT1R; E-prostanoid receptor 3; prostaglandin D2; c-fos; protein kinase G; extracellular signal-regulated kinase; macrophage inflammatory protein 1β; cys-LT; Cysteinyl leukotriene; CysLT1R; Cysteinyl leukot
In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition
Keywords: پروستاگلاندینها; AA; arachidonic acid; CV; cardiovascular; COX; cyclooxygenase coxibs; COX-2; selective inhibitors; DMEM; Dulbecco's modified eagle's medium; EIA; enzyme immunoassay; IP; inositol phosphate; HEK293; human embryonic kidney 293; NSAID; nonsteroidal anti-
Rat aorta as a pharmacological tool for in vitro and in vivo studies
Keywords: پروستاگلاندینها; BH4; tetrahydrobiopterin; cGMP; cyclic guanine monophosphate; COX; cyclooxygenase; cNOS; constitutive NOS; DAG; diacylglycerol; DMEM; Dulbecco's modified eagle's medium; eNOS; endothelial NOS; EDHF; endothelium dependent hyperpolarization factor; EGTA; et
Gastroprotective activity of the rhizome ethanol extract of Zingiber simaoense Y. Y. Qian in rats
Keywords: پروستاگلاندینها; ZSE; Zingibersimaoense rhizome ethanol extract; PG; prostaglandin; GC-MS; gas chromatography-mass spectrometry; EtOH/HCl; acidified ethanol; MDA; malondialdehyde; NSAIDs; non-steroidal anti-inflammatory drugs; Indomethacin (PubChem CID: 3715); Cimetidin
A perspective review on role of novel NSAID prodrugs in the management of acute inflammation
Keywords: پروستاگلاندینها; Prostaglandin; Cyclooxygenase; Ulcerogenicity; Conjugation; Solubility; Lipophilicity; Nitroaspirin; Nanoprodrugs;
Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2
Keywords: پروستاگلاندینها; BMP; bone morphogenetic protein; BMPR1B; bone morphogenetic protein receptor-1B; CYP; cytochrome P450; DAVID; database for annotation visualization and integrated discovery; EET; epoxyeicosatrienoic acid; ERK; extracellular signal-regulated kinase; GAPDH;
Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions
Keywords: پروستاگلاندینها; DHET; dihydroxy-eicosatrienoic acid; HETE; hydroxy-eicosatetraenoic acid; LTB4; leukotriene B4; EpOME; epoxy-octadecenoic acid; EET; epoxy-eicosatrienoic acid; TXB2; thromboxane B2; PGD2; prostaglandin D2; HODE; hydroxy-octadecadienoic acid; DiHOME; dihyd
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy
Keywords: پروستاگلاندینها; CCI; Chronic constriction injury; cDNA; Complementary DNA; COX; Cyclooxygenase enzyme; DN; Diabetic neuropathy; ELISA; Enzyme-linked immunosorbent assay; eNOS; Endothelial nitric oxide synthase; H&E; Hematoxylin and eosin; IL-1β; Interleukin-1β; IL-6; I
The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects
Keywords: پروستاگلاندینها; NO; nitric oxide; NO2; dioxide radical; O2; superoxide; ONO2â; Â peroxynitrite; 15-dPGJ2; 15-deoxy-Î12,14-prostaglandin J2; AA; arachidonic acid; ADH; alcohol dehydrogenase; AF-1; ligand-independent activation function; AF-2; ligand-dependent activatio
In vitro COX-1 and COX-2 enzyme inhibitory activities of iridoids from Penstemon barbatus, Castilleja tenuiflora, Cresentia alata and Vitex mollis
Keywords: پروستاگلاندینها; Iridoids; Cyclooxygenase-2; Cyclooxygenase-1; Non-steroidal anti-inflammatory drugs; Prostaglandin;
Promising alternative clinical uses of prostaglandin F2α analogs: Beyond the eyelashes
Keywords: پروستاگلاندینها; alopecia areata; androgenic alopecia; bimatoprost; glaucoma; latanoprost; prostaglandin; prostaglandin F2α analog; travoprost; vitiligo
Evidence for prostaglandin E2 receptor expression in the intramural ganglia of the guinea pig urinary bladder
Keywords: پروستاگلاندینها; Bladder; Ganglion; Prostaglandin; EP1; EP2; Neuromodulation
Regulation of longitudinal esophageal motility in the house musk shrew (Suncus murinus)
Keywords: پروستاگلاندینها; Esophagus; Histamine; Mast cell; Prostaglandin; Serotonin;
Low-dose aspirin (acetylsalicylate) prevents increases in brain PGE2, 15-epi-lipoxin A4 and 8-isoprostane concentrations in 9 month-old HIV-1 transgenic rats, a model for HIV-1 associated neurocognitive disorders
Keywords: پروستاگلاندینها; AA; arachidonic acid; ART; antiretroviral therapy; ASA; acetylsalicylic acid; CNS; central nervous system; COX; cyclooxygenase; CSF; cerebrospinal fluid; DHA; docosahexaenoic acid; HAND; HIV-1 associated neurocognitive disorders; HETE; hydroxyeicosatetrae
n-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats
Keywords: پروستاگلاندینها; ARA; arachidonic acid; BHT; 2,6-di-t-butyl-4-methyl-phenol; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; 5-HETE; 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 12-HETE; 12-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid; 15-HETE; 15-hydroxy-5Z,8Z,1
Roles of mPGES-1, an inducible prostaglandin E synthase, in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis model
Keywords: پروستاگلاندینها; Lymphangiogenesis; Inflammation; Prostaglandin; Synthase; Cyclooxygenase-2; mPGES-1; Peritonitis
Les médicaments de la dysfonction érectile
Keywords: پروستاگلاندینها; alprostadil; complément alimentaire; dysfonction érectile; inhibiteur de la phosphodiestérase de type 5; prostaglandine; yohimbinealprostadil; erectile dysfunction; food supplement; phosphodiesterase type 5 inhibitor; prostaglandin; yohimbine
Reproductive performance of lactating dairy cattle after intrauterine administration of a prostaglandin F2α receptor antagonist 4 days after insemination
Keywords: پروستاگلاندینها; Cow; Prostaglandin; Pregnancy rate; Embryo;
Immunomodulation of mast cells by nutrients
Keywords: پروستاگلاندینها; AA; arachidonic acid; BMMC; bone marrow-derived mast cells; CBMC; cord blood-derived mast cells; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; EGCG; epigallocatechin-3-gallate; hiMC; human intestinal mast cells; IONO/PMA; calcium ionophore/phorbo
Translating Basic Research Into Clinical PracticeProstanoids in Asthma and COPD: Actions, Dysregulation, and Therapeutic Opportunities
Keywords: پروستاگلاندینها; cAMP; cyclic adenosine monophosphate; COX; cyclooxygenase; EP; E prostanoid receptor; Epac; exchange protein activated by cyclic adenosine monophosphate; GPCR; G protein-coupled receptor; IP; I prostanoid receptor; PG; prostaglandin; PKA; protein kinase A
Central mediators involved in the febrile response induced by polyinosinic-polycytidylic acid: Lack of involvement of endothelins and substance P
Keywords: پروستاگلاندینها; ANOVA; analysis of variance; dsRNA; double-stranded RNA; HLI; heat loss index; i.c.v; intracerebroventricular; IFN; interferon; IRF; interferon-regulatory factor; IL-1RA; interleukin-1 receptor antagonist; IL-1β; interleukin-1β; IL-6; interleukin-6; IL-
Immunopharmacology and inflammationThiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo
Keywords: پروستاگلاندینها; Prostaglandin; NSAIDs; Cyclooxygenase; Thiazole derivatives; Air pouch model of inflammation; Platelet aggregation;
New UHPLC-QqQ-MS/MS method for quantitative and qualitative determination of free phytoprostanes in foodstuffs of commercial olive and sunflower oils
Keywords: پروستاگلاندینها; ALA; α-linolenic acid; AA; Arachidonic Acid; GC-MS; gas chromatography coupled to mass spectrometry; HPLC; high performance liquid chromatography; ICH; International Conference on Harmonization; LOD; limit of detection; LOQ; limit of quantification; MR
In vivo mechanical loading rapidly activates β-catenin signaling in osteocytes through a prostaglandin mediated mechanism
Keywords: پروستاگلاندینها; Osteocyte; Mechanical loading; Wnt/β-catenin signaling; Prostaglandin;
Determining cyclooxygenase-2 activity in three different test systems utilizing online-solid phase extraction-liquid chromatography-mass spectrometry for parallel quantification of prostaglandin E2, D2 and thromboxane B2
Keywords: پروستاگلاندینها; Online-SPE; Mass spectrometry; Prostaglandin; Cyclooxygenase
The misleading nature of in vitro and ex vivo findings in studying the impact of stress hormones on NK cell cytotoxicity
Keywords: پروستاگلاندینها; NK cytotoxicity; Cortisol; Prostaglandin; Epinephrine; In vitro; Ex vivo; In vivo; Stress; Human; Whole blood;
Formation of the early canine CL and the role of prostaglandin E2 (PGE2) in regulation of its function: An in vivo approach
Keywords: پروستاگلاندینها; Dog (Canis familiaris); Prostaglandin; CL;
Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells
Keywords: پروستاگلاندینها; HSC; hepatic stellate cell; LD; lipid droplet; TAG; triacylglycerol; ACSL; long-chain acyl-CoA synthetase; PC; phosphatidylcholine; AA; Arachidonic acid; AA-d8; deuterated arachidonic acid; PL; phospholipid; Prostaglandin; Eicosanoid; Phosphatidylcholine;
Dichotomous role of protein kinase A type I (PKAI) in the tumor microenvironment: A potential target for 'two-in-one' cancer chemoimmunotherapeutics
Keywords: پروستاگلاندینها; Anti-tumor immunity; AS-PKAI; Chemoimmunotherapeutics; Immunosurveillance; 'Two-in-one'; Tumor reversion; 3LL; Lewis lung carcinoma; AC; adenylyl cyclase; AS-PKAI; antisense oligonucleotide targeted against RI/PKAI; ATP; adenosine-5'-triphosphate; bFG
Modulation by gamithromycin and ketoprofen of in vitro and in vivo porcine lipopolysaccharide-induced inflammation
Keywords: پروستاگلاندینها; Gamithromycin; Ketoprofen; Lipopolysaccharide; Tumour necrosis factor-α; Interleukin-6; Interleukin-1β; Prostaglandin; PBMC; Pig;
Fatal and Near-fatal Anaphylaxis
Keywords: پروستاگلاندینها; Anaphylaxis; Allergy; Fatalities; Cardiovascular; Histamine; Prostaglandin; Leukotriene;
Pathophysiology of the hepoxilins
Keywords: پروستاگلاندینها; AA; arachidonic acid; AMG9810; (2E)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide; Apaf-1; Apoptotic protease activating factor 1; BAPTA; 1,2-Bis(o-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid; CCCP; carbonyl cya
Oxytocin activates NF-κB-mediated inflammatory pathways in human gestational tissues
Keywords: پروستاگلاندینها; OT; oxytocin; OTR; oxytocin receptor; MAPK; mitogen activated protein kinase; PG; prostaglandin; PKC; protein kinase C; PLC; phospholipase C; PIP2; phosphatidylinositol 4,5-bisphosphate; IP3; inositol trisphosphate; DAG; diacyl-glycerol; OVT; ornithine va
Gingerols and shogaols: Important nutraceutical principles from ginger
Keywords: پروستاگلاندینها; BSA; bovine serum albumin; COX; cyclooxygenase; GN; gingerol; HepG2; human hepatoma G2; iNOS; inducible NO synthase; LPS; lipopolysaccharide; MBC; minimum bactericidal concentration; MIC; minimal inhibitory concentration; NF-κB; nuclear factor-kappa B; N
Network pharmacology for antiepileptogenesis: Tolerability of multitargeted drug combinations in nonepileptic vs. post-status epilepticus mice
Keywords: پروستاگلاندینها; AED; antiepileptic drug; AT1; angiotensin II type 1; COX; cyclooxygenase; i.h.; intrahippocampal; IL; interleukin; NMDA; N-methyl-d-aspartate; PG; prostaglandin; SE; status epilepticus; SRS; spontaneous recurrent seizures; TGF-β; transforming growth fact
Stromal Indian Hedgehog Signaling Is Required for Intestinal Adenoma Formation in Mice
Keywords: پروستاگلاندینها; COX2; Prostaglandin; Mouse Model; Colon Cancer; α-Sma Sma; α-Sma smooth muscle actin; Bmp; bone morphogenetic protein; BrdU; bromodeoxyuridine; Cyp1a1Cre; cytochrome p450-1a1Cre; Gli1; glioma-associated oncogene; Hhip; Hedgehog-interacting protein; Ihh;
Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma
Keywords: پروستاگلاندینها; AHR; airway hyper-responsiveness; AUC; area under the curve; BALF; bronchoalveolar lavage fluid; cAMP; cyclic adenosine monophosphate; CRTH2; chemoattractant receptor homologous molecule expressed on Th2 cells; Cmax; maximum concentration achieved after d
Protein supplementation during a short-interval prostaglandin-based protocol for timed AI in sheep
Keywords: پروستاگلاندینها; Oestrus synchronisation; Prostaglandin; Focus feeding; Ovulation rate; Timed artificial insemination; Ewes;
Detection of estrous behavior in buffalo heifers by radiotelemetry following PGF2α administration during the early or late luteal phase
Keywords: پروستاگلاندینها; Radiotelemetry; Buffalo heifers; Prostaglandin; Synchronization; Estrus
Production of prostaglandins in transgenic Arabidopsis thaliana
Keywords: پروستاگلاندینها; AA; arachidonic acid; DGLA; di-homo-γ-linolenic acid; EPA; eicosapentaenoic acid; PG; prostaglandin; PGFS; prostaglandin F synthase; PGHS or COX; prostaglandin H synthase; Prostaglandins; Arabidopsis thaliana; Very long chain polyunsaturated fatty acids;
Microwave Ablation of Osteoid Osteomas Using Dynamic MR Imaging for Early Treatment Assessment: Preliminary Experience
Keywords: پروستاگلاندینها; NSAID; nonsteroidal antiinflammatory drug; PG; prostaglandin; RF; radiofrequency; SI; signal intensity; 3D; three-dimensional; TWIST; time-resolved imaging with stochastic trajectories;
Mast Cell Activation Disorders
Keywords: پروستاگلاندینها; Mast cells; Mastocytosis; Mast cell activation syndromes; Diagnosis; Treatment; Tryptase c-kit; AHNMD; Associated hematologic clonal non-mast cell disease; MCAS; Mast cell activation syndrome; MMAS; Monoclonal mast cell activation syndrome; PG; Prostagl
Structure-activity relationship studies and biological characterization of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
Keywords: پروستاگلاندینها; HPGD; 15-PGDH; Prostaglandin; PGE2; Inhibitor;
Prostaglandin modulates TLR3-induced cytokine expression in human astroglioma cells
Keywords: پروستاگلاندینها; Prostaglandin; Astrocyte; Toll-like receptor; Cytokine; G-protein coupled receptor;
Lack of complete regression of the Day 5 corpus luteum after one or two doses of PGF2α in nonlactating Holstein cows
Keywords: پروستاگلاندینها; Prostaglandin; Luteolysis; Dairy cow; Corpus luteum
The effect of numbers of frozen-thawed boar sperm and addition of prostaglandin F2α at insemination on fertility in pigs
Keywords: پروستاگلاندینها; Artificial insemination; Frozen boar sperm; Fertility; Prostaglandin; Swine; Litter size