Acquisition of chemoresistance following discontinuous exposures to cisplatin is associated in ovarian carcinoma cells with progressive alteration of FAK, ERK and p38 activation in response to treatment
Keywords: پروتئین کیناز فعال شده با میتوژن; CDDP, cisplatin (cis-diamino-dichloro-platinum(II)); DAPI, 4′,6-diamidino-2-phenylindole; ERK, extracellular signal-regulated kinase; FAK, focal adhesion kinase; Jak, Janus kinase; MAPK, mitogen-activated protein kinase; PARP, poly(ADP-ribose) polymerase;