Keywords: P-گلیکوپروتئین; Controlled release/delivery; efflux pumps; multidrug resistance; cancer; P-glycoprotein;
مقالات ISI P-گلیکوپروتئین (ترجمه نشده)
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Keywords: P-گلیکوپروتئین; Anticancer drugs; Lipid model membranes; Drug transport; Drug resistance; P-glycoprotein;
Keywords: P-گلیکوپروتئین; P-gp; P-glycoprotein; CYP-3A4; cytochrome P450 3A4; AUC; area under plasma concentration curve; CVS; cardiac vascular system; CNS; central nervous system; BaP; benzo(a)pyrene; PIP; piperine; CUR; curcumin; MCF-7; Michigan Cancer Foundation-7; Bioenhancer;
Keywords: P-گلیکوپروتئین; 5FU; 5-fluorouracile; ABC; ATP-binding cassette; AUC; area under the curve; BCRP; breast cancer resistance protein; Cmax; maximum (peak) plasma concentration; CYP; cytochrome p450 enzymes; DDI; drug-drug interactions; EIAEDS; enzyme-inducing antiepilept
Keywords: P-گلیکوپروتئین; In vitro assay; Anthelmintic resistance; Cattle nematodes; Cytochrome P450; P-glycoprotein; β-Tubulin; Pyrosequencing;
Keywords: P-گلیکوپروتئین; SiNPs; silica nanoparticles; MSNs; mesoporous silica nanoparticles; C/S SiNPS; core/shell silica nanoparticle; QDs; quantum dots; MRI; magnetic resonance imaging; PET; positron emission tomography; X-ray CT; X-ray computed tomography; TEOS; tetraethyl ort
Keywords: P-گلیکوپروتئین; AAN; aristolochic acid nephropathy; ADME; absorption, distribution, metabolism and excretion; CYT P450; cytochrome P450; DPP-IV; dipeptidyl peptidase IV; GLP1; glucagon like peptide 1; GLUT4; glucose transporter 4; GSH; glutathione; GST; glutathione-S-tra
Keywords: P-گلیکوپروتئین; P-glycoprotein; Verapamil; Moxidectin; Pharmacokinetics; Foetal sheep;
Keywords: P-گلیکوپروتئین; Cancer; Drug sequestration; Microparticle; Multidrug resistance; P-glycoprotein;
Keywords: P-گلیکوپروتئین; Buprenorphine; P-glycoprotein; Respiratory depression; Gender differences; Strain differences; Blood-brain barrier;
Keywords: P-گلیکوپروتئین; Supersaturated polymeric micelle; Cyclosporine A; Soluplus®; Supersaturation degree; Oral bioavailability; Cellular uptake and transport; CsA; cyclosporine A; CsD; cyclosporine D; P-gp; P-glycoprotein; PMs; polymeric micelles; HPMC-AS; hydroxypropyl meth
Keywords: P-گلیکوپروتئین; APC; apparent partition coefficient; BCRP; breast cancer resistance protein; CH; cholate; cLPM; canalicular liver plasma membrane; DC; deoxycholate; GC; glycocholate; GDC; glycodeoxycholate; HNAP; hydroxy-2-naphthoic acid; Mw; molecular weight; MATE; mult
Keywords: P-گلیکوپروتئین; biliary excretion; hepatocytes; clearance; drug transport; hepatobiliary disposition; in vitro/in vivo correlations (IVIVC); organic aniontransporting polypeptide transporters; P-glycoprotein;
Keywords: P-گلیکوپروتئین; siRNA; small interfering RNA; AON; antisense oligonucleotides; shRNA; small hairpin RNA; pDNA; plasmid DNA; CYP3A; cytochrome P450 3A; MDR; multidrug resistance; MDR1; multidrug resistance protein 1; Pgp; P-glycoprotein; TRAIL; tumor necrosis factor-relat
Keywords: P-گلیکوپروتئین; Dirofilaria immitis; Heartworm; ABC transporter; Single nucleotide polymorphism; P-glycoprotein;
Keywords: P-گلیکوپروتئین; Pregabalin; Fibromyalgia; P-glycoprotein
Keywords: P-گلیکوپروتئین; Conferone; P-glycoprotein; Angiopoietin-1; Reactive oxygen species; Colorectal adenocarcinomaP-gp, P-glycoprotein; VEGF, vascular endothelial growth factor; Ang-1, angiopoietin-1; Ang-2, angiopoietin- 2; EC, endothelial cell; VEGFR-1, - 2, vascular endoth
Keywords: P-گلیکوپروتئین; P-glycoprotein; ABCB1; MDR1; Antidepressant treatment; Side effects; Major depressive disorder
Keywords: P-گلیکوپروتئین; Herb-drug interaction; Metabolism; Cytochrome P-450 enzyme system; P-glycoprotein; Review
Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations
Keywords: P-گلیکوپروتئین; Chitosan; Brij-S20; Solubility; P-Glycoprotein; Drug efflux;
Effects of carbamazepine on the P-gp and CYP3A expression correlated with PXR or NF-κB activity in the bEnd.3 cells
Keywords: P-گلیکوپروتئین; Drug-resistant epilepsy; Carbamazepine; Pregnane X receptor; Nuclear factor kappa B; P-glycoprotein; Cytochrome P450; Brain microvascular endothelial cells;
Astragali radix and its main bioactive compounds activate the Nrf2-mediated signaling pathway to induce P-glycoprotein and breast cancer resistance protein
Keywords: P-گلیکوپروتئین; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; HQ; Astragali radix; AS-IV; astragaloside IV; CS; calycosin; FMNT; formononetin; Nrf2; nuclear factor E2-related factor-2; HDIs; herb-drug interactions; AREs; antioxidant response elements; K
The influence of compatibility of Si-Ni decoction with metabolism in intestinal bacteria on transports of toxic diterpenoid alkaloids from processed aconite root across Caco-2 monolayers
Keywords: P-گلیکوپروتئین; AD; Decoction of processed aconite root; ALD; Decoction of processed aconite root and honey-processed liquorice; AP; Apical; BCRP; Breast cancer resistance protein; BL; Basolateral; DDAs; Diester-diterpenoid alkaloids; EIC; Extracted ion chromatogram; ER;
P-glycoprotein polymorphism and levothyroxine bioavailability in hypothyroid patients
Keywords: P-گلیکوپروتئین; P-glycoprotein; MDR1 polymorphisms; Levothyroxine; Hypothyroidism;
In vitro assessment of the interactions of dopamine β-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein
Keywords: P-گلیکوپروتئین; BBB; blood-brain barrier; BCRP; Breast Cancer Resistance Protein; BSA; bovine serum albumin; DAD; diode-array detection; DBH; dopamine β-hydroxylase; DDIs; drug-drug interactions; DMSO; dimethyl sulfoxide; EMA; European Medicines Agency; HBSS; Hanks bala
Blood-brain barrier permeability and neuroprotective effects of three main alkaloids from the fruits of Euodia rutaecarpa with MDCK-pHaMDR cell monolayer and PC12 cell line
Keywords: P-گلیکوپروتئین; EF; Euodiae Fructus; EDM; evodiamine; RCP; rutaecarpine; DEDM; dehydroevodiamine; Papp; apparent permeability coefficients; P-gp; P-glycoprotein; MPP+; 1-methyl-4-phenylpyridinium ion; H2O2; hydrogen peroxide; TCM; traditional Chinese medicine; BBB; blood
Toxic effects of prolonged exposure to [C14mim]Br on Caenorhabditis elegans
Keywords: P-گلیکوپروتئین; Chronic toxicity; Imidazolium-based ILs; Caenorhabditis elegans; Detoxification; P-glycoprotein;
Retina Compatible Interactions and Effective Modulation of Blood Ocular Barrier P-gp Activity by Third-Generation Inhibitors Improve the Ocular Penetration of Loperamide
Keywords: P-گلیکوپروتئین; P-gp inhibitors; electroretinography; elacridar; tariquidar; blood aqueous barrier (BAB); blood retinal barrier (BRB); ABC; adenosine tri-phosphate-binding cassette; AH; aqueous humor; BAB; blood aqueous barrier; BM; Bruch's membrane; BOB; blood ocular
TIPE2 sensitizes osteosarcoma cells to cis-platin by down-regulating MDR1 via the TAK1- NF-κB and - AP-1 pathways
Keywords: P-گلیکوپروتئین; OS; Osteosarcoma; MDR1; Multidrug resistance protein 1; P-gp; p-glycoprotein; TIPE2; Tumor necrosis factor TNF- alpha induced protein 8-like 2; EAE; Autoimmune encephalomyelitis; MDR; Multidrug resistance; PI; Propidium iodide; HCC; Hepatocellular carcino
Activation of P-glycoprotein and CYP 3A by Coptidis Rhizoma in vivo: Using cyclosporine as a probe substrate in rats
Keywords: P-گلیکوپروتئین; Cyclosporine; P-glycoprotein; Cytochrome P450 3A; Herb-drug interactions; Pharmacokinetics;
Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
Keywords: P-گلیکوپروتئین; AhR; aryl hydrocarbon receptor; AP1; activating protein 1; ARE; antioxidant-response element; CAR; constitutive androstane receptor; CYP; cytochrome P450; DREs; dioxin-responsive elements; EMSA; electromobility gel shift assay; FBS; fetal bovine serum; GS
Regulation of human brain vascular pericytes and human astrocytes in a blood-brain barrier model using human brain microvascular endothelial cells: Expression of TGF-β1, VEGF, MMP-9 and P-gp
Keywords: P-گلیکوپروتئین; Transforming growth factor-β1; Vascular endothelial growth factor; Matrix metalloproteinase; P-glycoprotein; Calcein-AM; Inhibitor;
Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis
Keywords: P-گلیکوپروتئین; Euphorbia nicaeensis; Euphorbiaceae; Diterpenoids; Jatrophanes; Isolation; Structutre determination; P-glycoprotein; Multi-drug resistance;
Design, synthesis and preclinical evaluation of 5-methyl-N4-aryl-furo[2,3-d]pyrimidines as single agents with combination chemotherapy potential
Keywords: P-گلیکوپروتئین; RTKs; Receptor tyrosine kinases; VEGF; vascular endothelial growth factor; VEGFR-2; vascular endothelial growth factor receptor-2; PDGFR-β; platelet-derived growth factor receptor-β; EGFR; epidermal growth factor receptor; ATP; adenosine triphosphate; N
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics
Keywords: P-گلیکوپروتئین; ABC; ATP-binding cassette transporter; ADAR; adenosine deaminase acting on RNA; ADH; alcohol dehydrogenase; AhR; aryl hydrocarbon receptor; AKR; aldo-keto reductase; ALS; amyotrophic lateral sclerosis; AZIN1; antizyme inhibitor 1; AMPA; α-amino-3-hydroxy
MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer
Keywords: P-گلیکوپروتئین; MDR; multi-drug resistance; qRT-PCR; quantitative real-time PCR; BCRP; breast cancer resistance protein; PTEN; phosphatase and tensin homolog deleted on chromosome ten; DMEM; Dulbecco's Modified Eagle medium; RPMI 1640; Roswell Park Memorial Institute m
The effects of DMARDs on the expression and function of P-gp, MRPs, BCRP in the treatment of autoimmune diseases
Keywords: P-گلیکوپروتئین; DMARDs; Autoimmune diseases; Multidrug resistance; ABC transporters; P-glycoprotein;
Reversal effect of quercetin on multidrug resistance via FZD7/β-catenin pathway in hepatocellular carcinoma cells
Keywords: P-گلیکوپروتئین; Quercetin; Hepatocellular carcinoma; Multiple drug resistance; ATP-binding cassette transporters, FZD7/β-catenin pathway; 5-FU; 5-fluorouracil; ABC; ATP-binding cassette; ATP; adenosine triphosphate; ADR; doxorubicin; FZD7; Frizzled homolog protein 7; GV
Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates
Keywords: P-گلیکوپروتئین; P-glycoprotein; Efflux ratio; ABCB1; MDR1-P-gp inhibitor; Digoxin; Rhodamine 123; Zosuquidar; Monolayer;
Interspecies comparison of putative ligand binding sites of human, rat and mouse P-glycoprotein
Keywords: P-گلیکوپروتئین; Species differences; P-glycoprotein; Binding site comparison; Transmembrane domain; Protein-ligand interaction fingerprint;
Microdialysis combined with RRLC-MS/MS for the pharmacokinetics of two major alkaloids of Bi qi capsule and the potential roles of P-gp and BCRP on their penetration
Keywords: P-گلیکوپروتئین; BQC; Bi qi capsule; BBB; blood-brain barrier; RRLC-MS/MS; rapid resolution liquid chromatography -tandem mass spectrometry; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; CNS; central nervous system; CSF; cerebrospinal fluid; LLOQ; lower li
Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2
Keywords: P-گلیکوپروتئین; ABC; ATP-binding cassette; AUC; area under the curve; BBB; blood-brain barrier; BCRP; breast cancer resistance protein; GBM; glioblastoma; MGMT; O6-methylguanine-DNA methyltransferase; MRI; magnetic resonance imaging; P-gp; P-glycoprotein; WT; wild-type;
The combination of Puerariae Lobatae Radix and Chuanxiong Rhizoma enhanced the absorption and pharmacokinetics of puerarin by modulating the intestinal barrier and influenced gut microbiota
Keywords: P-گلیکوپروتئین; Puerarin; Ligustrazine; Absorption; Pharmacokinetics; Intestinal barrier; Gut microbiota; Puerarin (PubChem CID: 5281807); Daidzein (PubChem CID: 5281708); Daidzin (PubChem CID: 107971); Ligustrazine (PubChem CID: 14296); PLR; Puerariae Lobatae Radix; CXR
Leukemia biomarker detection by using photoconductive response of CNT electrode: Analysis of sensing mechanism based on charge transfer induced Fermi level fluctuation
Keywords: P-گلیکوپروتئین; Optical biosensor; Carbon nanotubes; Fermi level; Chronic myeloid leukemia; P-glycoprotein;
P-glycoprotein-9 and macrocyclic lactone resistance status in selected strains of the ovine gastrointestinal nematode, Teladorsagia circumcincta
Keywords: P-گلیکوپروتئین; Teladorsagia circumcincta; Anthelmintic resistance; P-glycoprotein; Ivermectin;
Cytotoxicity and cellular mechanisms of toxicity of CuO NPs in mussel cells in vitro and comparative sensitivity with human cells
Keywords: P-گلیکوپروتئین; AcP; Acid phosphatase; CAT; catalase; DLS; dynamic light scattering; DMSO; dimethyl sulphoxide; EDTA; ethylenediaminetetraacetic acid; MTT; thiazolyl blue tetrazolium bromide; MXR; multixenobiotic resistance; NP; nanoparticle; NR; neutral red; PBS; phosph
Mesoporous silica nanoparticles for drug and gene delivery
Keywords: P-گلیکوپروتئین; AO; acridine orange; APTES; 3-aminopropyltriethoxysilane; APTMS; amino propyl trimethoxysilane; BCL-2; B-cell lymphoma-2; BCS; Biopharmaceutical Classification System; Bio-TEM; biological transmission electron microscopy; C dots; Cornell dots; CMC; critic
TPGS-functionalized and ortho ester-crosslinked dextran nanogels for enhanced cytotoxicity on multidrug resistant tumor cells
Keywords: P-گلیکوپروتئین; Dextran; Ortho ester; Nanogel; P-glycoprotein; Multidrug resistance;
Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13
Keywords: P-گلیکوپروتئین; Nematode; Haemonchus contortus; ABC transporters; P-glycoprotein; Ivermectin; Homology modeling; ABC; ATP-binding cassette; ACD; actinomycin D; AH; anthelmintic; BlastP; protein Basic Local Alignment Search Tool; bp; base pairs; Cel; Caenorhabditis elegan
Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents
Keywords: P-گلیکوپروتئین; MDR reversers; P-gp modulators; Piperazine derivatives; Chemosensitizers; Doxorubicin-resistant human erythroleukemia K562â¯cells (K562/DOX); Pirarubicin uptake; P-gp; P-glycoprotein; MRP1; Multidrug Resistance associated Protein 1; BCRP; Breast Cancer R