دانلود مقالات ISI درباره ژن PTEN + ترجمه فارسی

N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy

Keywords: ژن PTEN; Prostate cancer; Androgen signaling; Taxanes; Therapeutic resistance; Epithelial-mesenchymal transition; ADT; androgen deprivation therapy; AR; androgen receptor; AR-V; androgen receptor splice variant; CRPC; castration-resistant prostate cancer; DHT; dih

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Actin cytoskeleton organization, cell surface modification and invasion rate of 5 glioblastoma cell lines differing in PTEN and p53 status

Keywords: ژن PTEN; CGM; complete growth medium; ECM; extracellular matrix; Erk; extracellular signal regulated kinase; FAK; focal adhesion kinase; FBS; fetal bovine serum; GBM; Glioblastoma multiforme; MEK; MAPK/Erk kinase; MMP; matrix metalloproteinase; PTEN; phosphatase a

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells

Keywords: ژن PTEN; AR; Androgen receptor; AZ; Antizyme; AZI; Antizyme inhibitor; AP-1; Activator protein 1; BR; Brassinosteroid; Bcl-2; B-cell lymphoma 2; DiOC6; 3,3′-dihexyloxacarbocyanineiodide; CHENSpm; N1-ethyl-N11-((cycloheptyl)methy)-4,8-diazaundecane; DAPI; 4′,6-

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation

Keywords: ژن PTEN; AVSDs; atrioventricular septal defects; ASDs; atrial septal defects; SV; spina vestibuli; DMP; dorsal mesenchymal protrusion; PAS; primary atrial septum; SHF; second heart field; HOS; Holt-Oram syndrome; Osr1; Odd-skipped 1; Tbx5; Osr1; Atrioventricular

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate

Keywords: ژن PTEN; PTEN; C-terminal tail; Phosphorylation; Phosphatase; Phosphatidylinositol-4,5-bisphosphate; Kinetics

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

Keywords: ژن PTEN; 6-OHDA; 6-hydroxy-dopamine; Akt, PKB; protein kinase B, serine/threonine-specific protein kinase; BDNF; brain derived neurotrophic factor; CaMKIIβ; calcium-calmodulin-dependent protein kinase II β isoform; cAMP; 3′,5′-cyclic adenosine monophosphate;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo

Keywords: ژن PTEN; 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated viral vector; Bcl-2; B-cell lymphoma 2; CNS; central nervous system; ctl; contralateral; DAPI; 4′,6-diamidino-2-phenylindole; DIV; day in vitro; DOPAC; 3,4-dihydroxyphenylacetic acid; EGFP; enhanced green

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy

Keywords: ژن PTEN; α-SMA; α-smooth muscle actin; COL1A1; collagen type I alpha 1; COL3A1; collagen type III alpha 1; COL6A1; collagen type VI alpha 1; DMD; Duchenne muscle dystrophy; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FBN1; fibrillin 1;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Genistein increases estrogen receptor beta expression in prostate cancer via reducing its promoter methylation

Keywords: ژن PTEN; 5-Aza-dC; 5-Aza-2′-deoxycytidine; AR; androgen receptor; DMSO; dimethyl sulfoxide; DNMT; DNA methyltransferase; ER-β; estrogen receptor beta; FOXO-1; forkhead box O-1; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; MBD; methyl binding domain; MSP; me

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Physiology and pathophysiology of IGFBP-1 and IGFBP-2 – Consensus and dissent on metabolic control and malignant potential

Keywords: ژن PTEN; IGFBP-1; IGFBP-2; metabolism; diabetes; obesity; cancer; AKT; PTEN; steroids

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer

Keywords: ژن PTEN; Triple-negative breast cancer; Epidermal growth factor receptor; PTEN; shRNA screen;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Associate editor: B. TeicherTargeting the genetic alterations of the PI3K-AKT-mTOR pathway: Its potential use in the treatment of bladder cancers

Keywords: ژن PTEN; Urothelial bladder cancer; PI3K; AKT; PTEN; mTOR; TSC1; AMPK; AMP-activated protein kinase; Bad; B cell leukemia/lymphoma-2 associated death agonist; Bcl-2; B cell leukemia-2; Bim; B cell leukemia/lymphoma-2 interacting mediator of cell death; CREB; cycli

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of hippocampal synaptic plasticity by BDNF

Keywords: ژن PTEN; 4E-BPs; eIF4E-binding proteins; 5-HT; 5-hydroxytryptamine; ADF; actin-depolymerising factor; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPAR; AMPA receptors; Arc; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived n

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice

Keywords: ژن PTEN; GSH; Glutathione; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; IR; Insulin receptor; MR; Methionine restriction; mTORC1; Mechanistic target of rapamycin complex 1; NAFLD; Non-alcoholic fatty liver disease; p70S6K; p70 ribosomal S6 kinase; PIP3; P

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

The role of Myc and let-7a in glioblastoma, glucose metabolism and response to therapy

Keywords: ژن PTEN; GBM; glioblastoma multiforme; let-7a; lethal-7a; miRNA; microRNA; TCGA; The Cancer Genome Atlas; GLUT; glucose transporter; PKM2; pyruvate kinase M2; PDK; pyruvate dehydrogenase kinase; MGMT; O6-methylguanine-DNA methyltransferase; GSK3β; glycogen syntha

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting strategies on miRNA-21 and PDCD4 for glioblastoma

Keywords: ژن PTEN; GBM; glioblastoma multiforme; miRNAs; microRNAs; PDCD4; programmed cell death 4; EMT; epithelial-mesenchymal transition; JNK; Jun N-terminal protein kinase; PTEN; phosphatase and tensin homolog; PI3K/AKT; phosphatidylinositol-3 kinase/Akt; MAPK/ERK; mit

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells

Keywords: ژن PTEN; AMPK; AMP-activated protein kinase; ACC; Acyl COA Carboxylase; BSA; Bovine Serum Albumin; DHE; Dihydroethidium; DPI; Diphenylene iodonium; ERK; Extracellular signal-regulated kinase; FAS; Fatty Acid Synthase; FBS; Fetal bovine serum; FOXO1; Forkhead box p

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Exome Sequencing Reveals Germline SMAD9 Mutation That Reduces Phosphatase and Tensin Homolog Expression and Is Associated With Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas

Keywords: ژن PTEN; Hamartomatous Polyps; Ganglioneuromas; Colorectal Cancer; SMAD Signaling; BMP; bone morphogenetic protein; CS; Cowden syndrome; HPS; hamartomatous polyposis syndromes; JPS; juvenile polyposis syndrome; miR21; microRNA 21; mRNA; messenger RNA; PTEN; phosph

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations

Keywords: ژن PTEN; 5-LOX; 5-lipoxygenase; AP-1; activating protein 1; cGMP; cyclic guanosine monophosphate; ERK; extracellular signal-regulated kinase; GSH; glutathione (reduced); GSSG; glutathione (oxidized); H2O2; hydrogen peroxide; HIF-α; hypoxia inducible factor alpha;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

mTORC1 Up-Regulates GP73 to Promote Proliferation and Migration of Hepatocellular Carcinoma Cells and Growth of Xenograft Tumors in Mice

Keywords: ژن PTEN; Liver Cancer; Mouse Model; Drug; Signal Transduction; DEN; diethylnitrosamine; GP73; Golgi protein 73; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; MEF; mouse embryonic fibroblast; MMP; matrix metalloproteinase; mTOR; mec

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2015 سفارش ترجمه

Postoperative Dural Arteriovenous Fistula in a Patient with Cowden Disease: A Case Report

Keywords: ژن PTEN; Cowden disease; dural arteriovenous fistula; vascular endothelial growth factor; cavernous hemangioma; PTEN

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

TMPRSS2-ERG Fusions Are Strongly Linked to Young Patient Age in Low-grade Prostate Cancer

Keywords: ژن PTEN; Prostate cancer; Age; Early onset; Gene fusion; TMPRSS-ERG; ERG; Deletion; PTEN; 6q; 5q; Prognosis; Molecular; Subtype;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Peroxisome proliferator activated receptor gamma (PPARγ) as a therapeutic target for improvement of cognitive performance in Fragile-X

Keywords: ژن PTEN; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CNS; central nervous system; ECM; extra cellular matrix; FMR1 gene; Fragile X mental retardation 1 gene; FMRP; Fragile-X mental retardation protein; FXS; Fragile X syndrome; GLUT-3; gl

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Reciprocal positive regulation between TRPV6 and NUMB in PTEN-deficient prostate cancer cells

Keywords: ژن PTEN; TRPV6; Numb; PTEN; Prostate cancer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Preparation and optimization of new 4-(2-(indolin-1-yl)-2-oxoethyl)-2-morpholinothiazole-5-carboxylic acid and amide derivatives as potent and selective PI3Kβ inhibitors

Keywords: ژن PTEN; PI3Kβ; pAKT; PTEN; Thiazole;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Human relevance of NRAS/BRAF mouse melanoma models

Keywords: ژن PTEN; PTEN; β-Catenin; p16INK4A; Melanomagenesis; Initiation; Progression

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Plenary ArticlePTEN inhibitor bisperoxovanadium protects oligodendrocytes and myelin and prevents neuronal atrophy in adult rats following cervical hemicontusive spinal cord injury

Keywords: ژن PTEN; bpV; PTEN; Spinal cord injury; Oligodendrocyte survival; Neuron atrophy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

miR-17 inhibitor suppressed osteosarcoma tumor growth and metastasis via increasing PTEN expression

Keywords: ژن PTEN; Osteosarcoma; miR-17; PTEN; Proliferation; Migration; Invasion

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Vinculin negatively regulates transcription of MT1-MMP through MEK/ERK pathway

Keywords: ژن PTEN; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FAK; focal adhesion kinase; MT1-MMP; membrane-type 1 matrix metalloproteinase; PBS; phosphate-buffered saline; PTEN; phosphatase and tensi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondria: A kinase anchoring protein 1, a signaling platform for mitochondrial form and function

Keywords: ژن PTEN; AKAP; A kinase anchoring protein; BAD; Bcl-2-associated death promoter; cAMP; cyclic AMP; CaN; calcineurin; Casp; caspase; Drp1; dynamin-related protein 1; Fo-f; ATP synthase Fo complex; HIF-1a; hypoxia induced factor 1a; KH; K homology; LPL; lipoprotein

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Reversible oxidation of PRL family protein-tyrosine phosphatases

Keywords: ژن PTEN; Cys; cysteine; DTNB; 5,5′-dithiobis-2-nitrobenzoic acid; DTT; dithiothreitol; GSH; glutathione; IPTG; isopropyl-β-d-thiogalactopyranoside; MKP; MAP kinase phosphatase; NADPH; nicotinamide adenine dinucleotide phosphate; NEM; N-ethlymaleimide; PIP3; pho

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

PTEN overexpression improves cisplatin-resistance of human ovarian cancer cells through upregulating KRT10 expression

Keywords: ژن PTEN; MDR, multi-drug resistance; FBS, fetal bovine serum; PBS, phosphate-buffered saline; PCR, polymerase chain reaction; PVDF, Polyvinylidene fluorideCisplatin; KRT10; Multi-drug resistance; Ovarian cancer; PTEN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting miR-21 sensitizes Ph+ ALL Sup-b15 cells to imatinib-induced apoptosis through upregulation of PTEN

Keywords: ژن PTEN; ALL; acute lymphoblastic leukaemia; CML; chronic myelogenous leukemia; miRNA; microRNA; qRT-PCR; quantitative real-time PCR; MiR-21; Imatinib; Sup-b15 cells; Apoptosis; PTEN;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

MicroRNA-429 induces tumorigenesis of human non-small cell lung cancer cells and targets multiple tumor suppressor genes

Keywords: ژن PTEN; Non-small cell lung cancer; MiR-429; Metastasis; PTEN; RASSF8; TIMP2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

CXCR4 and PTEN are involved in the anti-metastatic regulation of anethole in DU145 prostate cancer cells

Keywords: ژن PTEN; Anethole; Prostate cancer; Metastasis; CXCR4; PTEN;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The role of PTEN tumor suppressor pathway staining in carcinoma in situ of the bladder1

Keywords: ژن PTEN; Bladder cancer; PTEN; Carcinoma in situ;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Bariatric surgery-induced weight loss changes immune markers in the endometrium of morbidly obese women

Keywords: ژن PTEN; Endometrial cancer prevention; Obesity; Immunity; Inflammation; CD20; CD3; PTEN; Endometrial hyperplasia;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Correlation of over-expressions of miR-21 and Notch-1 in human colorectal cancer with clinical stages

Keywords: ژن PTEN; Colorectal cancer; Notch-1; miR-21; PTEN; Clinic stages

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Comparative analyses of individual and multiple alterations of p53, PTEN and p16 in non-small cell lung carcinoma, glioma and breast carcinoma samples

Keywords: ژن PTEN; p53; PTEN; p16; Non-small cell lung carcinoma; Glioma; Breast carcinoma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Loss of PP2A and PTEN immunoexpression coexists with survivin overexpression in adenomyosis

Keywords: ژن PTEN; Adenomyosis; PP2A; PTEN; Survivin; PI3K/AKT signaling

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

PTEN in smooth muscle cells is essential for colonic immune homeostasis

Keywords: ژن PTEN; PTEN; Smooth muscle cell; Lymphoid follicle; Immune activation; Akt1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of INPP4B gene transfection combined with PARP inhibitor on castration therapy-Resistant prostate cancer cell line, PC3

Keywords: ژن PTEN; INPP4B; Combined; PARP inhibitor; Castration therapy-resistant prostate cancer; PC3; PTEN;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Phenotypes associated with inherited and developmental somatic mutations in genes encoding mTOR pathway components

Keywords: ژن PTEN; mTOR; Mamalian target of rapamycin; PI3K; phosphoinositide 3-kinase related kinase; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; AMP; Adenosine monophosphate; ATP; Adenosine triphosphate; S6K; ribosomal S6 Kinase; 4E-BP1; eukaryotic initiation factor 4

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Upregulated microRNA-301a in breast cancer promotes tumor metastasis by targeting PTEN and activating Wnt/β-catenin signaling

Keywords: ژن PTEN; PTEN; phosphatase and tensin homolog; UTR; untranslated region; ORF; open reading frame; TCF; T cell factor; LEF; lymphoid enhancer factor; mir-301a; Breast cancer; Wnt/β-catenin; PTEN;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Best practice for PTEN gene and protein assessment in anatomic pathology

Keywords: ژن PTEN; PTEN; Immunohistochemistry; Fluorescent in situ hybridization; Human; Prostatic neoplasm; Renal cell carcinoma;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

PTEN methylation involved in benzene-induced hematotoxicity

Keywords: ژن PTEN; Benzene; PTEN; Epigenetic modifications; Hematotoxicity; Methylation-specific PCR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Glucose modulates Pax6 expression through the JNK/p38 MAP kinase pathway in pancreatic beta-cells

Keywords: ژن PTEN; Pax6; Glucose; JNK; p38 MAP kinase; PTEN; Beta-cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

miR-181a mediates metabolic shift in colon cancer cells via the PTEN/AKT pathway

Keywords: ژن PTEN; miR-181a; PTEN; Glycolysis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Acquired isochromosome 12p, somatic TP53 and PTEN mutations, and a germline ATM variant in an adolescent male with concurrent acute megakaryoblastic leukemia and mediastinal germ cell tumor

Keywords: ژن PTEN; Germ cell tumor; acute megakaryoblastic leukemia; isochromosome 12p; TP53; PTEN; ATM

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Chromosome 20q13.2 ZNF217 locus amplification correlates with decreased E-cadherin expression in ovarian clear cell carcinoma with PI3K-Akt pathway alterations

Keywords: ژن PTEN; Ovarian clear cell carcinoma; ZNF217; E-cadherin; PIK3CA; PTEN; Prognosis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه