دانلود مقالات ISI درباره فسفاتیدیل اینوزیتول -3 + ترجمه فارسی

Akt isoforms regulate intermediate filament protein levels in epithelial carcinoma cells

Keywords: فسفاتیدیل اینوزیتول -3; IF, intermediate filaments; K8/18, keratins 8 and 18; vim, vimentin; PI3K, phosphatidylinositol 3-kinase; CA-Akt1, constitutively activated Akt1; TGF-β1, transforming growth factor β1; shRNA, short hairpin RNA; GAPDH, glyceraldehyde-3-phosphate dehydrogen

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Transcriptional activation of peroxisome proliferator-activated receptor-γ requires activation of both protein kinase A and Akt during adipocyte differentiation

Keywords: فسفاتیدیل اینوزیتول -3; PPAR-γ, peroxisome proliferator-activated receptor-γ; PKA, protein kinase A; PI3K, phosphatidylinositol 3-kinase; IBMX, 3-isobutyl-1-methylxantine; C/EBP-β, CCAAT/enhancer-binding protein-β; MAPK, mitogen-activated protein kinase; JNK, c-Jun N-terminal ki

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Knockdown of Akt isoforms by RNA silencing suppresses the growth of human prostate cancer cells in vitro and in vivo

Keywords: فسفاتیدیل اینوزیتول -3; AR, androgen receptor; BLAST, Basic Local Alignment Search Tool; EDTA, ethylenediaminetetraacetic acid; FBS, fetal bovine serum; PI3K, phosphatidylinositol 3-kinase; PTEN, phosphatase and tensin homolog deleted from chromosome 10; RNAi, RNA interference;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway

Keywords: فسفاتیدیل اینوزیتول -3; DIV, day in vitro; E, embryonic day; ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2; LPA, lysophosphatidic acid; MAPK, mitogen activated protein kinase; PI3K, phosphatidylinositol 3-kinase; PLC, phospholipase C; ROCK, Rho-associated coiled-coil

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Tensin2 reduces intracellular phosphatidylinositol 3,4,5-trisphosphate levels at the plasma membrane

Keywords: فسفاتیدیل اینوزیتول -3; PTPase, phosphatase; PTEN, phosphatase and tensin homologue deleted on chromosome 10; PI3K, phosphatidylinositol 3-kinase; PtdIns(3,4,5)P3, phosphatidylinositol 3,4,5-trisphosphate; PtdIns(4,5)P2, phosphatidylinositol 4,5-bisphosphate; RTK, receptor tyros

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

NMR characterization of hydrophobic collapses in amyloidogenic unfolded states and their implications for amyloid formation

Keywords: فسفاتیدیل اینوزیتول -3; NMR, nuclear magnetic resonance; R1ρ, transverse relaxation rate in the rotating frame; NOE, nuclear overhauser effect; HSQC, heteronuclear single-quantum coherence; RDC, residual dipolar coupling; PI3K, phosphatidylinositol 3-kinase; SH3, Src homology 3;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Blockade of the ERK or PI3K–Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib

Keywords: فسفاتیدیل اینوزیتول -3; EGFR, epidermal growth factor receptor; CML, chronic myeloid leukemia; NSCLC, non-small cell lung cancer; TKI, tyrosine kinase inhibitor; ERK, extracellular signal-regulated kinase; PI3K, phosphatidylinositol 3-kinase; HDAC, histone deacetylase; ROS, reac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

The death effector domain-containing DEDD forms a complex with Akt and Hsp90, and supports their stability

Keywords: فسفاتیدیل اینوزیتول -3; DEDD; Akt; Glucose uptake; Cdk1DEDD, death effector domain-containing DNA binding protein; Cdk1, cyclin-dependent kinase-1; S6K1, S6 kinase-1; PI3K, phosphatidylinositol 3-kinase; rRNA, ribosomal RNA; TOR, target of rapamycin; mTOR, mammalian TOR; 5′-TOP,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Mutation of tyrosine residue 857 in the PDGF β-receptor affects cell proliferation but not migration

Keywords: فسفاتیدیل اینوزیتول -3; PDGF, platelet-derived growth factor; PDGFR, PDGF receptor; Erk, extracellular regulated kinase; PAE, porcine aortic endothelial cell; PI3K, phosphatidylinositol 3-kinase; FBS, fetal bovine serum; SH2, Src homology 2; SHP-2, SH2-domain containing phosphat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

B-type natriuretic peptide protect cardiomyocytes at reperfusion via mitochondrial calcium uniporter

Keywords: فسفاتیدیل اینوزیتول -3; B-type natriuretic peptide; Mitochondrial calcium uniporter; CardiomyocytesBNP, B-type natriuretic peptide; I/R, ischemia/reperfusion; MCU, mitochondrial calcium uniporter; PI3K, phosphatidylinositol 3-kinase; ROS, reactive oxygen species

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

Keywords: فسفاتیدیل اینوزیتول -3; PAK1, p21-activated kinase 1; CRC, colorectal carcinoma or cancer; MAPK, mitogen-activated protein kinase; MEK, mitogen activated kinase/ERK kinase; ERK, extracellular signal-regulated kinase; PI3K, phosphatidylinositol 3-kinase; VEGF, vascular endothelia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

New insights into the function of Atg9

Keywords: فسفاتیدیل اینوزیتول -3; Atg, autophagy related; Cvt, cytoplasm-to-vacuole targeting; MAPK, mitogen activated protein kinase; p38IP, p38 MAPK interacting protein; MEF, mouse embryonic fibroblast; PI3K, phosphatidylinositol 3-kinase; PI3P, phosphatidylinositol-3-phosphate; S6K, S6

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The molecular therapy of colorectal cancer

Keywords: فسفاتیدیل اینوزیتول -3; CRC, colorectal cancer; Avastin, bevacizumab; VEGF, vascular endothelial growth factor; Erbitux, cetuximab; EGFR, epithelial growth factor receptor; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; HIF-1, hypoxia inducible fact

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene

Keywords: فسفاتیدیل اینوزیتول -3; SHP2, Src homology 2 (SH2)-containing protein tyrosine phosphatase 2; Gab1, Grb2-associated binder 1; WT, wild-type; RTK, receptor tyrosine kinase; PI3K, phosphatidylinositol 3-kinase; MAPK, mitogen activated protein kinase; ERK1/2, extracellular signal-r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

MiRNA-451 plays a role as tumor suppressor in human glioma cells

Keywords: فسفاتیدیل اینوزیتول -3; miRNA, microRNA; PI3K, phosphatidylinositol 3-kinase; AKT, AKT protein family, which members are also called protein kinases B; MMP, matrix metalloproteinases; EGFR, epidermal growth factor receptor; CDK, cyclin-dependent kinase; DMEM, Dulbecco's Modified

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Gα16 interacts with Class IA phosphatidylinositol 3-kinases and inhibits Akt signaling

Keywords: فسفاتیدیل اینوزیتول -3; Akt, protein kinase B; GPCR, G protein-coupled receptors; GTPase, GTP hydrolyase; HEK, human embryonic kidney; PI3K, phosphatidylinositol 3-kinase; PIP3, Phosphatidylinositol 3,4,5-trisphosphate; PLCβ, phospholipase CβG protein; Gα16; Phosphatidylinositol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

KMUP-1 attenuates serum deprivation-induced neurotoxicity in SH-SY5Y cells: Roles of PKG, PI3K/Akt and Bcl-2/Bax pathways

Keywords: فسفاتیدیل اینوزیتول -3; BDNF, brain-derived neurotrophic factor; cGMP, cyclic guanosine monophosphate; CREB, cAMP response element-binding protein; nNOS, neuronal nitric oxide synthase; PDE, phosphodiesterase; PI3K, phosphatidylinositol 3-kinase; PKG, cGMP-dependent protein kina

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Meloxicam protects cell damage from 1-methyl-4-phenyl pyridinium toxicity via the phosphatidylinositol 3-kinase/Akt pathway in human dopaminergic neuroblastoma SH-SY5Y cells

Keywords: فسفاتیدیل اینوزیتول -3; PD, Parkinson's disease; MPP+, 1-methyl-4-phenyl pyridinium; PI3K, phosphatidylinositol 3-kinase; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; COX, cyclooxygenase; NSAIDs, nonsteroidal antiinflammatory drugs; MEK, MAP-ERK kinase; MAP, mitogen activ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking

Keywords: فسفاتیدیل اینوزیتول -3; CTS, cardiotonic steroids; EE fractions, Rab5- and EEA-1-positive early endosome fractions; EGFR, epidermal growth factor receptor; IP3R, IP3 receptor; MBG, marinobufagenin; NHE3, Na+/H+ exchanger isoform 3; PI3K, phosphatidylinositol 3-kinase; PKC, prote

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Novel Expression Patterns of PI3K/Akt/mTOR Signaling Pathway Components in Colorectal Cancer

Keywords: فسفاتیدیل اینوزیتول -3; CRC, colorectal cancer; IHC, immunohistochemistry; mTOR, mammalian target of rapamycin; PI3K, phosphatidylinositol 3-kinase; S6K, p70 S6 kinase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death

Keywords: فسفاتیدیل اینوزیتول -3; SOD, superoxide dismutase; ROS, reactive oxygen species; PI, propidium iodide; MAPK, mitogen-activated protein kinase; JNK, c-jun N-terminal kinase; ERK, extracellular signaling-regulated protein kinase; PI3K, phosphatidylinositol 3-kinase; GSK-3β, glycog

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Role of α2/δ subunit in the development of morphine-induced rewarding effect and behavioral sensitization

Keywords: فسفاتیدیل اینوزیتول -3; gabapentin; morphine; α2/δ subunit of voltage-gated calcium channels; rewarding effect; behavioral sensitization; neuronal plasticityGBP, gabapentin; mGluR5, metabotropic glutamate receptor 5; MRP, morphine; PI3K, phosphatidylinositol 3-kinase; PKC, prote

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Leptin exerts an anti-apoptotic effect on human dendritic cells via the PI3K-Akt signaling pathway

Keywords: فسفاتیدیل اینوزیتول -3; JAK, Janus kinase; MAPK, mitogen-activated protein kinase; NF-kB, nuclear factor-kappa B; PI3K, phosphatidylinositol 3-kinase; STAT, signal trasducers and activator of transcriptionLeptin; Apoptosis; Dendritic cell

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

p62 protects SH-SY5Y neuroblastoma cells against H2O2-induced injury through the PDK1/Akt pathway

Keywords: فسفاتیدیل اینوزیتول -3; Ad, adenovirus; MOI, multiplicity of infection; MTT, 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide; PDK, 3-phosphoinositide-dependent kinase; PI3K, phosphatidylinositol 3-kinase; PKB, protein kinase B; PKC, protein kinase CAkt; H2O2; p62; PD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Differential regulation of Akt/protein kinase B isoforms during cell cycle progression

Keywords: فسفاتیدیل اینوزیتول -3; MEF, mouse embryo fibroblast; PI3K, phosphatidylinositol 3-kinase; PtdIns-(3,4,5)P3, phosphatidylinositol 3,4,5-trisphosphate; PTEN, phosphatase and tensin homolog; PKB, protein kinase B; PH, pleckstrin homology; mTOR, mammalian target of rapamycinAkt/pro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Mechanisms of estrogen signaling and gene expression via GPR30

Keywords: فسفاتیدیل اینوزیتول -3; cAMP, cyclic adenosine monophosphate; EGF(R), epidermal growth factor (receptor); ER(s), estrogen receptor(s); ERE, estrogen response element; GPCR, G protein-coupled receptor; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of estrogen on AF64A-induced apoptosis in NG108-15 cells

Keywords: فسفاتیدیل اینوزیتول -3; AF64A, ethylcholine aziridinium; PI3K, phosphatidylinositol 3-kinase; MEK, mitogen-activated protein kinase kinase; ERK, extracellular signal-regulated kinase; CTL-1, choline transporter-like protein-1; CHT, high-affinity choline transporter; OCT, organic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Osteopontin increases lung cancer cells migration via activation of the αvβ3 integrin/FAK/Akt and NF-κB-dependent pathway

Keywords: فسفاتیدیل اینوزیتول -3; NSCLCs, non-small cell lung cancers; ECM, extracellular matrix; OPN, osteopontin; FAK, focal adhesion kinase; PI3K, phosphatidylinositol 3-kinase; IKK α/β, IκB kinase α/β; NF-κB, nuclear factor-κBOPN; Lung cancer; Integrin; Migration; FAK

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER

Keywords: فسفاتیدیل اینوزیتول -3; cAMP, cyclic adenosine monophosphate; EGF(R), epidermal growth factor (receptor); ER(s), estrogen receptor(s); ERE, estrogen response element; GPCR, G protein-coupled receptor; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; P

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation

Keywords: فسفاتیدیل اینوزیتول -3; Reactive oxygen species (ROS); PI3K/Akt; Bax; Mitochondria; ApoptosisDMEM, Dulbecco's modified Eagle's medium; DTT, dithiothreitol; EDTA, ethylene diamine tetra acetic acid; H2O2, hydrogen peroxide; PI3K, phosphatidylinositol 3-kinase; ROS, reactive oxyge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Transforming growth factor-β1 increases cell migration and β1 integrin up-regulation in human lung cancer cells

Keywords: فسفاتیدیل اینوزیتول -3; TGF, transforming growth factor; ECM, extracellular matrix; PI3K, phosphatidylinositol 3-kinase; IKKα/β, IκB kinase α/β; NF-κB, nuclear factor-κBTGF-β1; Lung cancer; Integrin; Migration; NF-κB; Akt

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-α-induced upregulation of matrix metalloproteinase-9: Its direct inhibition by quercetin

Keywords: فسفاتیدیل اینوزیتول -3; MMP, matrix metalloproteinase; ECM, extracellular matrix; TNF-α, tumor necrosis factor-α; TNFR, TNF receptor; NF-κB, nuclear factor-κB; AP-1, activator protein-1; PI3K, phosphatidylinositol 3-kinase; PKB, protein kinase B; TPA, 12-O-tetradecanoylphorbol-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Nav1.7 sodium channel-induced Ca2+ influx decreases tau phosphorylation via glycogen synthase kinase-3β in adrenal chromaffin cells

Keywords: فسفاتیدیل اینوزیتول -3; cPKC-α, conventional protein kinase C-α; DAG, diacylglycerol; DMSO, dimethyl sulfoxide; GSK-3, glycogen synthase kinase-3; IP3, inositol 1,4,5-trisphosphate; PI3K, phosphatidylinositol 3-kinase; PIP2, phosphatidylinositol 4,5-bisphosphate; PIP3, phosphati

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

2,3′,4,4′,5′-Pentamethoxy-trans-stilbene, a resveratrol derivative, is a potent inducer of apoptosis in colon cancer cells via targeting microtubules

Keywords: فسفاتیدیل اینوزیتول -3; PI3K, phosphatidylinositol 3-kinase; Akt, protein kinase B; MAPK, mitogen-activated protein kinase; Erk, extracellular signal-regulated kinase; p38, p38 mitogen-activated protein kinases; JNK, c-Jun amino-terminal kinase; U0126, 1,4-diamino-2,3-dicyano-1,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

EGF-recruited JunD/c-fos complexes activate CD2AP gene promoter and suppress apoptosis in renal tubular epithelial cells

Keywords: فسفاتیدیل اینوزیتول -3; EGF, epidermal growth factor; CD2AP, CD2-associated protein; AP-1, activator protein-1; PI3K, phosphatidylinositol 3-kinase; tsp, transcription start point; siRNA, small interfering RNA; EMSA, electromobility shift assay; PCR, polymerase chain reaction; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Hepatocyte growth factor induces delayed STAT3 phosphorylation through interleukin-6 expression

Keywords: فسفاتیدیل اینوزیتول -3; HGF/SF, Hepatocyte growth factor/Scatter factor; NGF, Nerve growth factor; TNF-α, Tumor necrosis factor-α; STATs, Signal transducers and activators of transcription; PI3K, phosphatidylinositol 3-kinase; MAPK, Mitogen-activated protein kinase; Erk, Extrace

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells

Keywords: فسفاتیدیل اینوزیتول -3; ROS, reactive oxygen species; UDCA, ursodeoxycholic acid; CHC, chronic hepatitis C; ALT, alanine aminotransferase; PI3K, phosphatidylinositol 3-kinase; Nrf2, nuclear factor-E2-related factor-2; GCL, glutamine-cysteine ligase; GSHS, GSH synthetase; CDCFH,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Anti-HLA I antibodies induce VEGF production by endothelial cells, which increases proliferation and paracellular permeability

Keywords: فسفاتیدیل اینوزیتول -3; AMR, antibody-mediated rejection; EC, endothelial cell; Fab, antigen binding fragment; Fc, crystallisable fragment; HLA I, human leukocyte antigen class 1; mTOR, mammalian target of rapamycin; SRL, sirolimus/rapamycin; PI3K, phosphatidylinositol 3-kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

CCL5 increases lung cancer migration via PI3K, Akt and NF-κB pathways

Keywords: فسفاتیدیل اینوزیتول -3; ECM, extracellular matrix; PI3K, phosphatidylinositol 3-kinase; IKK α/β, IκB kinase α/β; NF-κB, nuclear factor-κBCCL5; Lung cancer; Migration; Akt; PI3K

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling

Keywords: فسفاتیدیل اینوزیتول -3; eNOS, endothelial nitric oxide synthase; NO, nitric oxide; PI3K, phosphatidylinositol 3-kinase; VEGF, vascular endothelial growth factor; Epac, exchange protein directly activated by cAMP; HUVECs, human umbilical endothelial cells; PKA, cAMP-dependent pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-κB

Keywords: فسفاتیدیل اینوزیتول -3; cAMP, cyclic adenosine monophosphate; db-cAMP, dibutyryl-cAMP; i.pl., intrapleural; PDE4, phosphodiesterase 4; PI3K, phosphatidylinositol 3-kinase; NF-κB, nuclear factor kappa B; Akt/PKB, protein kinase B; EMSA, electrophoretic mobility shift assaycAMP; E

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Simultaneous loss of the DLC1 and PTEN tumor suppressors enhances breast cancer cell migration

Keywords: فسفاتیدیل اینوزیتول -3; DLC1, deleted in liver cancer 1; GAP, GTPase activating protein; GEF, guanine nucleotide exchange factor; LOH, loss of heterozygosity; PI3K, phosphatidylinositol 3-kinase; PIP3, phosphatidylinositol 3,4,5-trisphosphate; PTEN, phosphatase and tensin homolo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells

Keywords: فسفاتیدیل اینوزیتول -3; 5-Fluorouracil (5-Fu), 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors; PI3K, phosphatidylinositol 3-kinase; GSK3β, glycogen synthase kinase 3 beta; siRNA, small interference RNA; pAkt Ser473, phosphorylation of Akt on residue Ser473; pAkt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

α3β1 integrin promotes cell survival via multiple interactions between 14-3-3 isoforms and proapoptotic proteins

Keywords: فسفاتیدیل اینوزیتول -3; YAP, Yes-associated protein; PI3K, phosphatidylinositol 3-kinase; JNK, c-Jun NH2-terminal kinase; Ln5-P4, PPFLMLLKGSTR motif; FAK, focal adhesion kinase; NHEKs, normal human epidermal keratinocytes; KGM, keratinocyte growth medium; MTT, 3-(4,5-dimethylthi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of lamellipodia formation and cell invasion by CLIP-170 in invasive human breast cancer cells

Keywords: فسفاتیدیل اینوزیتول -3; HGF, hepatocyte growth factor; PI3K, phosphatidylinositol 3-kinase; siRNA, small interfering RNA; PIP3, phosphatidylinositol 3,4,5-triphosphate; RacGEF, Rac guanine nucleotide exchange factor; RNAi, RNA interference; FBS, fetal bovine serum; SDS, sodium d

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-κB signaling pathways

Keywords: فسفاتیدیل اینوزیتول -3; MMP, matrix metalloproteinase; HNE, 4-hydroxynonenal; ROS, reactive oxygen species; PI3K, phosphatidylinositol 3-kinase; NF-κB, nuclear factor-κB; VSMC, vascular smooth muscle cells; SOD, superoxide dismutase.4-Hydroxynonenal; MMP-2; Mitochondrial ROS; Ak

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

In vitro effect of gliclazide on DNA damage and repair in patients with type 2 diabetes mellitus (T2DM)

Keywords: فسفاتیدیل اینوزیتول -3; Endo III, endonuclease III; Fpg, formamidopyrimidine-DNA glycosylase; GPx, glutathione peroxidase; IRS, insulin receptor substrate; PI3K, phosphatidylinositol 3-kinase; ROS, reactive oxygen species; SODs, uperoxide dismutase; T2DM, type 2 diabetes mellitu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1α in the developing rat brain after hypoxia–ischemia

Keywords: فسفاتیدیل اینوزیتول -3; HIF-1α, hypoxia-inducible factor-1α; HI, hypoxia–ischemia; HIBD, hypoxia–ischemia brain damage; P10, postnatal day 10; PI3K, phosphatidylinositol 3-kinase; VEGF, vascular endothelial growth factorPhosphoinositid 3-kinase; HIF-1α; Development; Brain; Hypox

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Inflammation and insulin resistance

Keywords: فسفاتیدیل اینوزیتول -3; T2DM, type 2 diabetes mellitus; MetS, metabolic syndrome; TNF, tumor necrosis factor; CRP, C-reactive protein; PKC, protein kinase C; PI3K, phosphatidylinositol 3-kinase; PKB, protein kinase B; MAPK, mitogen activated protein kinase; IRS, insulin receptor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

PI3K/PTEN signaling in tumorigenesis and angiogenesis

Keywords: فسفاتیدیل اینوزیتول -3; PI3K, phosphatidylinositol 3-kinase; RTK, receptor tyrosine kinase; mTOR, mammalian target of rapamycin; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; FGFR, fibroblast growth factor receptor; IGF, insulin-like growth factor; IGF-1R

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه