دانلود مقالات ISI درباره فسفاتیدیل اینوزیتول -3 + ترجمه فارسی

The molecular mechanism of gypenosides-induced G1 growth arrest of rat hepatic stellate cells

Keywords: فسفاتیدیل اینوزیتول -3; HSCs, hepatic stellate cells; PI3K, phosphatidylinositol 3-kinase; p70S6K, 70-kDa ribosomal S6 kinase; PDGF, platelet-derived growth factor; MEK, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase; MAPK, mitogen-activated protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

TGF-β1 increases motility and αvβ3 integrin up-regulation via PI3K, Akt and NF-κB-dependent pathway in human chondrosarcoma cells

Keywords: فسفاتیدیل اینوزیتول -3; TGF-β1, transforming growth factor-β1; PI3K, phosphatidylinositol 3-kinase; IKKα/β, IκB kinase α/β; ECM, extracellular matrix; SDF-1, stromal cells-derived factor-1; NF-κB, nuclear factor-κBTGF-β1; Chondrosarcoma; Integrin; Migration; NF-κB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Oxidative and Nitrosative Stress and Fibrogenic Response

Keywords: فسفاتیدیل اینوزیتول -3; CYP2E1, Cytochrome P450 2E1; ECM, Extracellular matrix; ERK 1/2, Extracellular signal-regulated kinase 1/2; GSH, Glutathione; HSC, Hepatic stellate cells; H2O2, Hydrogen peroxide; IFNγ, Interferon γ; IL, Interleukin; MMPs, Matrix metalloproteinases; MAP

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2008 سفارش ترجمه

Akt up- and down-regulation in response to endoplasmic reticulum stress

Keywords: فسفاتیدیل اینوزیتول -3; ER stress, endoplasmic reticulum stress; PI3K, phosphatidylinositol 3-kinase; UPR, unfolded protein responseEndoplasmic reticulum stress; Phosphatidylinositol 3-kinase; Akt; Glial cell

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Immediate prostaglandin E2 synthesis in rat 3Y1 fibroblasts following vasopressin V1a receptor stimulation

Keywords: فسفاتیدیل اینوزیتول -3; PG, prostaglandin; AVP, arginine vasopressin; COX, cyclooxygenase; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; PLA2, phospholipase A2; PGES, PGE synthase; PKC, protein kinase C; IL-1, interleukin-1; TNF, tumor necrosis fac

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

XIAP is upregulated in HL-60 cells cocultured with stromal cells by direct cell contact

Keywords: فسفاتیدیل اینوزیتول -3; AML, acute myelogenous leukemia; PI3K, phosphatidylinositol 3-kinase; XIAP, X-linked inhibitor of apoptosis protein; IAPs, inhibitor of apoptosis proteins; ECM, extracelluar matrix; BMSCs, bone marrow stromal cells; DNR, daunorubicinStromal cell; Apoptosi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of SH2-domain containing inositol phosphatase 2 (SHIP2) in insulin producing INS1E cells improves insulin signal transduction and induces proliferation

Keywords: فسفاتیدیل اینوزیتول -3; βGal, beta-galactosidase; ERK1/2, extracellular signal-regulated kinases 1 and 2; GLP-1, glucagon-like peptide 1; GSK3, glycogen synthase kinase 3; PI3K, phosphatidylinositol 3-kinase; PKB (Akt), protein kinase B; PtdIns(3,4,5)P3, phosphatidylinositol 3,4

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of aging on triggering receptor expressed on myeloid cells (TREM)-1-induced PMN functions

Keywords: فسفاتیدیل اینوزیتول -3; PI3K, phosphatidylinositol 3-kinase; PMN, polymorphonuclear neutrophil; ERK, extracellular signal-regulated kinase; GM-CSF, granulocyte macrophage colony-stimulating factor; GM1, ganglioside M1; MFI, mean fluorescence intensity; MIP, macrophage inflammato

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

The depletion of cellular mitochondrial DNA causes insulin resistance through the alteration of insulin receptor substrate-1 in rat myocytes

Keywords: فسفاتیدیل اینوزیتول -3; IRS, insulin receptor substrate; GLUT4, facilitative glucose transporter isoform 4; PI3K, phosphatidylinositol 3-kinase; PDK-1, 3-phosphoinositide-dependent protein kinase-1; Akt2/PKB, protein kinase BmtDNA; GLUT4; Insulin resistance; IRS-1; Akt2/PKB

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Comparison of doxycycline and minocycline in the inhibition of VEGF-induced smooth muscle cell migration

Keywords: فسفاتیدیل اینوزیتول -3; ECM, extracellular matrix; HASMCs, human aortic smooth muscle cells; MMP, matrix metalloproteinase; PI3K, phosphatidylinositol 3-kinase; TIMP, tissue inhibitors of metalloproteinase; VEGF, vascular endothelial growth factorDoxycycline; Matrix metalloprote

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line

Keywords: فسفاتیدیل اینوزیتول -3; SCFAs, short-chain fatty acids; PTX, pertussis toxin; MAPK, mitogen-activated protein kinase; HSP27, heat shock protein 27; PMNC, polymorphonuclear cells; GPCR, G protein coupled receptors; PI3K, phosphatidylinositol 3-kinase; JNK, c-jun N-terminal kinase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Increased Incidence of Well-Differentiated Thyroid Cancer Associated with Hashimoto Thyroiditis and the Role of the PI3k/Akt Pathway

Keywords: فسفاتیدیل اینوزیتول -3; HT, Hashimoto thyroiditis; p-Akt, phosphorylated Akt; PTC, papillary thyroid cancer; FTC, follicular thyroid cancer; PI3K, phosphatidylinositol 3-kinase; SEER, Surveillance, Epidemiology and End Results; UTMB, The University of Texas Medical Branch

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species

Keywords: فسفاتیدیل اینوزیتول -3; VSMCs, vascular smooth muscle cells; IGF-I, insulin-like growth factor-I; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; EGFR, epidermal growth factor receptor; GPCR, G protein-coupled receptor; ROS, reactive oxygen species;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage

Keywords: فسفاتیدیل اینوزیتول -3; AR, aldose reductase; ORE, osmotic response element; Nrf2, nuclear factor-erythroid 2-related factor 2; DN-Nrf2, dominant negative Nrf2; MAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; ERK, extracellular signal-regulated kinas

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D2

Keywords: فسفاتیدیل اینوزیتول -3; PGD2, prostaglandin D2; CRTH2, chemoattractant receptor-homologous molecule expressed on Th2 cells (also named DP2); DP1, D prostanoid receptor 1; PI3K, phosphatidylinositol 3-kinase; NFAT, nuclear factor of activated T cells; GSK3β, glycogen synthase kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Role for Btg1 and Btg2 in growth arrest of WEHI-231 cells through arginine methylation following membrane immunoglobulin engagement

Keywords: فسفاتیدیل اینوزیتول -3; mIg, membrane Ig; PI3K, phosphatidylinositol 3-kinase; Btg, B cell translocation gene; PRMT, protein arginine methyltransferase; IFN, interferon; AdOx, adenosine-2′,3′-dialdehyde; PCR, polymerase chain reaction; EGFP, enhanced green fluorescent protein; P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury

Keywords: فسفاتیدیل اینوزیتول -3; PTEN; Akt; JNK; Hippocampus; Cerebral ischemia; Neuronal deathMAPK, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; PTPases, protein tyrosine phosphatases; PTEN, tumor suppressor phosphatase and tensin homolog deleted on chromosome

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Role of the α1 integrin cytoplasmic tail in the formation of focal complexes, actin organization, and in the control of cell migration

Keywords: فسفاتیدیل اینوزیتول -3; CHO, Chinese hamster ovary; FAK, focal adhesion kinase; GDI, guanine nucleotide dissociation inhibitor; GEF, guanine nucleotide exchange factor; PH, pleckstrin homology; PI3K, phosphatidylinositol 3-kinase; PIP2, phosphatidylinositol-4,5-bisphosphate; PIP

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

The Forkhead Transcription Factor FoxO1 Regulates Proliferation and Transdifferentiation of Hepatic Stellate Cells

Keywords: فسفاتیدیل اینوزیتول -3; HSC, hepatic stellate cell; FoxO, Forkhead box gene, group O; MnSOD, manganese superoxide dismutase; PI3K, phosphatidylinositol 3-kinase; α-SMA, α-smooth muscle actin; ECM, extracellular matrix; PDGF, platelet-derived growth factor; PPAR-γ, peroxisome pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Phosphorylation of the survival kinase Akt by superoxide is dependent on an ascorbate-reversible oxidation of PTEN

Keywords: فسفاتیدیل اینوزیتول -3; ROS, reactive oxygen species; O2−, superoxide; LY, LY294002; PI3K, phosphatidylinositol 3-kinase; PIP3, phosphatidylinositide 3,4,5-trisphosphate; MEFs, wild-type mouse embryonic fibroblasts; MEFPTEN −/−, PTEN knockout MEFs; FBS, fetal bovine serum; DDC,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Bioinformatics-based discovery and characterization of an AKT-selective inhibitor 9-chloro-2-methylellipticinium acetate (CMEP) in breast cancer cells

Keywords: فسفاتیدیل اینوزیتول -3; CMEP, 9-chloro-2-methylellipticinium acetate; GSK-3, glycogen synthase kinase-3; DAB, 3,3′ diaminobenzidine; HRG, heregulin; MTT, 3-[4,5-dimethythiazol-2-yl]2,5-diphenyltetrozolium bromide; PI3K, phosphatidylinositol 3-kinase; PKB, protein kinase B; mTOR,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

β-Catenin/Tcf-4 Inhibition After Progastrin Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors

Keywords: فسفاتیدیل اینوزیتول -3; APC, adenomatous polyposis coli; CRC, colorectal cancer; GAST, human gastrin gene; Gast, murine gastrin gene; ICAT, inhibitor of β-catenin and Tcf-4; ILK, integrin-linked kinase; PI3k, phosphatidylinositol 3-kinase; RIA, radioimmuno-assay; shRNA, short ha

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAIL-sensitive and TRAIL-resistant colon cancer cells

Keywords: فسفاتیدیل اینوزیتول -3; CK18, cytokeratin 18; DR, death receptor; ERK, extracellular signal-regulated kinase; FLIP, FLICE inhibitory protein; GSK, glycogen synthase kinase; MMP, mitochondrial membrane potential; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; PARP, p

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size

Keywords: فسفاتیدیل اینوزیتول -3; TOR, target of rapamycin; PI3K, phosphatidylinositol 3-kinase; MEF, mouse embryonic fibroblast; GFP, green fluorescent protein; Dox, doxycycline; PFA, paraformaldehyde; PI, propidium iodide; FSC-H, forward scatter heightAutophagy; Cell size; Starvation; A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCζ or mTOR in TPO-dependent cell lines and primary megakaryocytes

Keywords: فسفاتیدیل اینوزیتول -3; TPO, thrombopoietin; HSC, hematopoietic stem cell; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; mTOR, mammalian target of rapamycin; MAPK, mitogen activated protein kinase; EPO, erythropoietin; PDGF, platelet-derived growth factor; JNK, c-j

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Potent antiproliferative effects of resveratrol on human osteosarcoma SJSA1 cells: novel cellular mechanisms involving the ERKs/p53 cascade

Keywords: فسفاتیدیل اینوزیتول -3; resveratrol, RSVL; FBS, fetal bovine serum; DAPI, 4,6-diamidino-2-phenylindole; MAPK, mitogen-activated protein kinase; ERK1/2, extracellular signal-regulated kinase 1/2; PBS, phosphate-buffered saline; PI3K, phosphatidylinositol 3-kinase; PARP, poly(ADP-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Activation of muscarinic M4 receptor augments NGF-induced pro-survival Akt signaling in PC12 cells

Keywords: فسفاتیدیل اینوزیتول -3; mAChR, muscarinic acetylcholine receptor; GPCR, G protein-coupled receptor; NGF, nerve growth factor; RTK, receptor tyrosine kinase; CCh, carbachol; PTX, pertussis toxin; PI3K, phosphatidylinositol 3-kinase; PDGF, platelet-derived growth factor; EGF, epid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

The phosphatidylinositol 3-kinase/Akt pathway regulates the HCCR-1 oncogene expression

Keywords: فسفاتیدیل اینوزیتول -3; PI3K, phosphatidylinositol 3-kinase; PtdIns(4,5)P2, phosphatidylinositol-4,5-bisphosphate; PtdIns(3,4,5)P3, phosphatidylinositol-3,4,5-trisphosphate; PDK1, phosphoinositide-dependent kinase 1; SHIP, src-homology 2-containing phosphatase; PTEN, phosphatase

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Inhibition of sphingosine-1-phosphate- and vascular endothelial growth factor-induced endothelial cell chemotaxis by red grape skin polyphenols correlates with a decrease in early platelet-activating factor synthesis

Keywords: فسفاتیدیل اینوزیتول -3; pI3K, phosphatidylinositol 3-kinase; BAEC, bovine aortic endothelial cells; BCS, bovine calf serum; EC, endothelial cell; ECM, extracellular matrix; EDG, endothelial gene; S1P/EDG, endothelial gene signaling cascade activated by S1P; EBM-2, endothelial ce

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

A Novel Molecular Targeting Compound as K-samII/FGF-R2 Phosphorylation Inhibitor, Ki23057, for Scirrhous Gastric Cancer

Keywords: فسفاتیدیل اینوزیتول -3; ERK1, extracellular signal-regulated kinase 1; FGF-R, fibroblast growth factor receptor; IGF-IR, insulin-like growth factor-I receptor; MAP, mitogen-activated-protein; PDGF-R, platelet-derived growth factor receptor; PI3K, phosphatidylinositol 3-kinase; V

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1α expression through activation of AKT and P70S6K1 in human ovarian cancer cells

Keywords: فسفاتیدیل اینوزیتول -3; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; ROS, reactive oxygen species; VEGF, vascular endothelial growth factor; HIF-1, hypoxia-inducible factor-1; H2O2, hydrogen peroxide; PI3K, phosphatidylinositol 3-kinase; luc, luciferase;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Signalling and autophagy regulation in health, aging and disease

Keywords: فسفاتیدیل اینوزیتول -3; Insulin; Amino acids; ATP; AMPK; Phosphatidylinositol phospholipids; Neurodegenerative diseases; mTOR; Diabetes; CancerAtg, autophagy gene; IR, insulin receptor; IRS1,2, insulin receptor substrate 1 and 2; PI3K, phosphatidylinositol 3-kinase; PI(3)P, phos

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Probiotics and Commensals Reverse TNF-α– and IFN-γ–Induced Dysfunction in Human Intestinal Epithelial Cells

Keywords: فسفاتیدیل اینوزیتول -3; Ap, apical; Bl, basolateral; BT, Bacteroides thetaiotaomicron; FS, fluorescein sulfonic acid; IFN-γ, interferon gamma; JAK, Janus kinase; PI3K, phosphatidylinositol 3-kinase; SOCS, suppressor of cytokine signaling; ST/LA, Streptococcus thermophilus and La

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Src Homology 3 Domain of Hepatitis C Virus NS5A Protein Interacts With Bin1 and Is Important for Apoptosis and Infectivity

Keywords: فسفاتیدیل اینوزیتول -3; AD, activation domain; 3AT, 3-aminotriazole; DBD, DNA binding domain; 5FOA, 5-fluoroorotic acid; HCC, hepatocellular carcinoma; MBD, myc-binding domain; NLS, nuclear localization signal; NS5A, nonstructural protein 5A; PI3K, phosphatidylinositol 3-kinase;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes

Keywords: فسفاتیدیل اینوزیتول -3; 2-AG, 2-arachidonoylglycerol; DMSO, dimethyl sulfoxide; FBS, fetal bovine serum; HBSS, Hanks’ balanced salt solution; mAb, monoclonal antibody; MAP kinase, mitogen-activated protein kinase; PI3K, phosphatidylinositol 3-kinase; PTX, pertussis toxin; TPA, 1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Phosphorylation of cold shock domain/Y-box proteins by ERK2 and GSK3β and repression of the human VEGF promoter

Keywords: فسفاتیدیل اینوزیتول -3; CSD, cold shock domain; HRR, hypoxia responsive region; PI3K, phosphatidylinositol 3-kinase; MAPK, mitogen-activated protein kinaseVascular endothelial growth factor; Cold shock domain protein; Y-box protein; Gene repression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Platelet-activating factor induces matrix metalloproteinase-9 expression through Ca2+- or PI3K-dependent signaling pathway in a human vascular endothelial cell line

Keywords: فسفاتیدیل اینوزیتول -3; MMP, matrix metalloproteinase; PAF, platelet-activating factor; PI3K, phosphatidylinositol 3-kinase; ERK, extracellular signal-regulated kinase; MAPK, mitogen-activating protein kinaseMatrix metalloproteinase-9; Platelet-activating factor; Calcium; Phosph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه