دانلود مقالات ISI درباره پاسخ پروتئین آشکار + ترجمه فارسی

Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth

Keywords: پاسخ پروتئین آشکار; Selective cancer therapy; Unfolded protein response; 2DG; UPR disrupter; UPR; unfolded protein response; 2DG; 2-deoxy-D-glucose; IRE1; inositol-requiring enzyme 1; XBP1; X-box binding protein 1; GRP78; glucose-regulated protein 78 kDa; TM; tunicamycin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Candida albicans autophagy, no longer a bystander: Its role in tolerance to ER stress-related antifungal drugs

Keywords: پاسخ پروتئین آشکار; ER; endoplasmic reticulum; UPR; unfolded protein response; ATG; auophagy-related; MM-N; nitrogen source-depleted minimum medium; Cvt; cytosol-to-vacuole; TEM; transmission electron microscopy; PM; plasma membrane; cER; cytoplasmic ER; AP; autophagosome; E

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Towards defining the substrate of orphan P5A-ATPases

Keywords: پاسخ پروتئین آشکار; P5A-ATPase; Membrane transport; Primary active pump; Endoplasmic reticulum; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

On the role of 4-hydroxynonenal in health and disease

Keywords: پاسخ پروتئین آشکار; AD; Alzheimer's disease; ALDH; aldehyde dehydrogenase; AMI; acute myocardial infarction; ARE; antioxidant response element; CDK; cyclin-dependent kinase; CHF; chronic heart failure; DHLA; dihydrolipoic acid; ER; endoplasmic reticulum; GSH; glutathione; HL

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals

Keywords: پاسخ پروتئین آشکار; Armet; arginine-rich, mutated in early stage tumors; ATF4; activating transcription factor 4, a PERK downstream target; ATF6α; activating transcription factor 6α; CHOP; C/EBP homologous protein; DAPI; diamidino-2-phenylindole; EDEM1; ER degradation-enha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Demyelinating CMT–what’s known, what’s new and what’s in store?

Keywords: پاسخ پروتئین آشکار; Charcot–Marie–Tooth disease; Inherited neuropathies; Demyelinating neuropathies; PMP22; MPZ; Cx32; Unfolded protein response

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease

Keywords: پاسخ پروتئین آشکار; α-Synuclein; Unfolded protein response; ATF6; XBP1; Endoplasmic reticulum-associated degradation; COPII; Parkinson's disease; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis

Keywords: پاسخ پروتئین آشکار; AI; auto-inhibitory; CCT; CTP:phosphocholine cytidylyltransferase; CCTsol; soluble form of CCT; CCTmem; membrane-bound form of CCT; CT; cytidylyltransferase; ECT; ethanolamine-phosphate cytidylyltransferase; ERK; extracellular signal-regulated kinase; GCT

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Endoplasmic reticulum stress-mediated autophagy contributes to bluetongue virus infection via the PERK-eIF2α pathway

Keywords: پاسخ پروتئین آشکار; Bluetongue virus (BTV); Autophagy; Endoplasmic reticulum (ER) stress; PERK-eIF2α pathway; Replication; ER; endoplasmic reticulum; UPR; unfolded protein response; PERK; RNA-dependent protein kinase (PKR)-like endoplasmic reticulum (ER) kinase; eIF2α; the

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

Zebrafish: An Important Tool for Liver Disease Research

Keywords: پاسخ پروتئین آشکار; Development; Technology; Liver Cancer; Toxicology; Regeneration; ALD; alcoholic liver disease; CYP; cytochrome P450; DILI; drug-induced liver injury; DMBA; dimethylbenzanthracene; dpf; days postfertilization; ER; endoplasmic reticulum; FLD; fatty liver di

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: پاسخ پروتئین آشکار; AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Cis-element of the rice PDIL2-3 promoter is responsible for inducing the endoplasmic reticulum stress response

Keywords: پاسخ پروتئین آشکار; Protein disulfide isomerase; Endoplasmic reticulum stress; Unfolded protein response; Basic leucine zipper transcription factor; Oryza sativa

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Synthetic embryonic lethality upon deletion of the ER cochaperone p58IPK and the ER stress sensor ATF6α

Keywords: پاسخ پروتئین آشکار; ER stress; Unfolded protein response; Chaperones; Protein folding;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Deregulated unfolded protein response in chronic wounds of diabetic ob/ob mice: A potential connection to inflammatory and angiogenic disorders in diabetes-impaired wound healing

Keywords: پاسخ پروتئین آشکار; Wound healing; Diabetes mellitus; Chronic wounds; Unfolded protein response; ER stress;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation

Keywords: پاسخ پروتئین آشکار; ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; eIF2α; the eukaryotic initiation factor 2α; ER; endoplasmic reticulum; IRE1; inositol-requiring enzyme 1; PERK; double-stranded RNA-activated protein kinase (PKR)-like ER kinase; s

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

The p53/HSP70 inhibitor, 2-phenylethynesulfonamide, causes oxidative stress, unfolded protein response and apoptosis in rainbow trout cells

Keywords: پاسخ پروتئین آشکار; HSP70; heat shock protein70; BiP; binding immunoglobulin protein; ER; endoplasmic reticulum; 2-Phenylethynesulfonamide; Pifithrin-μ; Apoptosis; ROS; Unfolded protein response; ER stress;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy, a new determinant of plasma cell differentiation and antibody responses

Keywords: پاسخ پروتئین آشکار; Antibody; Atg5; Autophagy; B cell; Blimp-1; Endoplasmic reticulum; ER-phagy; Immunological memory; Multiple myeloma; Plasma cell; Proteostasis; Reticulophagy; Ubiquitin; Unfolded protein response; XBP-1; Ab; antibody; Ig; immunoglobulin; DC; dendritic cel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dipeptidyl petidase-IV inhibitor (gemigliptin) inhibits tunicamycin-induced endoplasmic reticulum stress, apoptosis and inflammation in H9c2 cardiomyocytes

Keywords: پاسخ پروتئین آشکار; ROS; reactive oxygen species; GLP-1; glucagon-like peptide-1; DPP-IV; dipeptidyl peptidase-IV; Erk; extracellular signal-regulated kinases; ER; endoplasmic reticulum; IL-6; interlukin-6; TNF-α; tumor necrosis factor-α; BNP; brain natriuretic peptide; SD

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation

Keywords: پاسخ پروتئین آشکار; GA; gambogic acid; Ver; verapamil; Ab; antibody; ER; endoplasmic reticulum; ROS; reactive oxygen species; z-VAD-FMK; carbobenzoxy-valyl-alanyl-aspartyl-(O-methyl)-fluoromethylketone; CT-like; chymotrypsin-like; DCFH-DA; 2′,7′-dichlorfluorescein-diacet

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Hypomyelinating leukodystrophy-associated missense mutant of FAM126A/hyccin/DRCTNNB1A aggregates in the endoplasmic reticulum

Keywords: پاسخ پروتئین آشکار; Endoplasmic reticulum; FAM126A; Hypomyelinating leukodystrophy; Unfolded protein response

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Progesterone production is affected by unfolded protein response (UPR) signaling during the luteal phase in mice

Keywords: پاسخ پروتئین آشکار; Corpus luteum; ER stress; Progesterone production; Unfolded protein response; Luteal phase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

HLA-B27 misfolding and ankylosing spondylitis

Keywords: پاسخ پروتئین آشکار; MHC class I; Protein misfolding; Endoplasmic reticulum stress; Unfolded protein response; Autophagy; Ankylosing spondylitis; Spondyloarthritis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Unfolded protein response prevents blastocyst formation during preimplantation embryo development in vitro

Keywords: پاسخ پروتئین آشکار; Preimplantation embryo development; endoplasmic reticulum stress; unfolded protein response; apoptosis; developmental arrest;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Estrogen reduces endoplasmic reticulum stress to protect against glucotoxicity induced-pancreatic β-cell death

Keywords: پاسخ پروتئین آشکار; ER; endoplasmic reticulum; UPR; unfolded protein response; GRP-78; glucose-regulated protein 78; CHOP; CCAAT/enhancer-binding protein homologous protein; PI; propidium iodide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide thiazolyl bl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib

Keywords: پاسخ پروتئین آشکار; ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Deficiency of IRE1 and PERK Signal Pathways in Systemic Lupus Erythematosus

Keywords: پاسخ پروتئین آشکار; Endoplasmic reticulum stress; Systemic lupus erythematosus; Unfolded protein response; Correlation analysis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Keywords: پاسخ پروتئین آشکار; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells

Keywords: پاسخ پروتئین آشکار; cataracts; valproic acid; ER stress; DNA methylation; unfolded protein response; Nrf2; Keap1 promoter demethylation; ARCs; age-related cataracts; ATF4; activating transcription factor 4; BiP; immunoglobulin heavy-chain binding protein; CHOP; C/EBP-homolog

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Triggering unfolded protein response by 2-Deoxy-d-glucose inhibits porcine epidemic diarrhea virus propagation

Keywords: پاسخ پروتئین آشکار; Porcine epidemic diarrhea virus; Endoplasmic reticulum stress; Unfolded protein response; 2-Deoxy-d-glucose; Antiviral;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health Study

Keywords: پاسخ پروتئین آشکار; Endoplasmic reticulum stress; Unfolded protein response; Epidemiology; Matched-pair analysis; Case-control studies; Gene expression pattern analysis; Cardiovascular diseases; Metabolic diseases;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Acrolein activates cell survival and apoptotic death responses involving the endoplasmic reticulum in A549 lung cells

Keywords: پاسخ پروتئین آشکار; AFC; amino trifluorocoumarin; AKT; protein kinase B; AMC; amino methylcoumarin; ARE; antioxidant response element; ATF6; activating transcription factor-6; BAPTA-AM; 1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid tetrakis (acetoxymethyl ester); Ba

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis

Keywords: پاسخ پروتئین آشکار; Apoptosis; Cerebral ischemia; Endoplasmic reticulum stress; Mesencephalic astrocyte-derived neurotrophic factor; Middle cerebral artery occlusion; Unfolded protein response

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning

Keywords: پاسخ پروتئین آشکار; ATF3; Unfolded protein response; Ischemic preconditioning; Infarct size; inflammatory response;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress – An experimental and modeling study

Keywords: پاسخ پروتئین آشکار; ER, endoplasmic reticulum; mTOR, mammalian target of rapamycin; UPR, unfolded protein responseAutophagy; Apoptosis; Endoplasmic reticulum stress; Metyrapone; Unfolded protein response; mTOR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of the Proapoptotic Unfolded Protein Response in Plaques of the Human Carotid Artery

Keywords: پاسخ پروتئین آشکار; Apoptosis; Immunohistochemistry; Carotid stenosis; Atherosclerotic plaque; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Mono-allelic and bi-allelic ENPP1 deficiency promote post-injury neointimal hyperplasia associated with increased C/EBP homologous protein expression

Keywords: پاسخ پروتئین آشکار; Artery media calcification; Generalized arterial calcification of infancy; ER stress; Unfolded protein response; CHOP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Cigarette smoke-induced lung endothelial apoptosis and emphysema are associated with impairment of FAK and eIF2α

Keywords: پاسخ پروتئین آشکار; Cigarette smoke; Lung; Endothelial cell; Apoptosis; Emphysema; Focal adhesion kinase; eIF2alpha; Unfolded protein response; Autophagy; AKR mice

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Getting RIDD of RNA: IRE1 in cell fate regulation

Keywords: پاسخ پروتئین آشکار; endoplasmic reticulum stress; unfolded protein response; RNase; IRE1; RIDD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease

Keywords: پاسخ پروتئین آشکار; Pharmacological chaperone; Chaperoning; Nicotine; nAChR; Tobacco; Neuroprotection; Parkinson's disease; Neurodegeneration; Unfolded protein response; Dopaminergic; Endoplasmic reticulum stress; FRET; TIRF; Confocal; ER exit sites; Golgi; Ligand; COPII; CO

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The effect of pioglitazone on aldosterone and cortisol production in HAC15 human adrenocortical carcinoma cells

Keywords: پاسخ پروتئین آشکار; DDIT3; eIF2α; Endoplasmic reticulum stress; PPAR; Unfolded protein response; Zona glomerulosa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: پاسخ پروتئین آشکار; Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of androgen receptor and glucose-regulated protein 78 kDa in human hepatocarcinogenesis

Keywords: پاسخ پروتئین آشکار; AR; ER-stress; GRP78; HCC; Sorafenib; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Restoration of lung surfactant protein D by IL-6 protects against secondary pneumonia following hemorrhagic shock

Keywords: پاسخ پروتئین آشکار; Unfolded protein response; Hemorrhagic shock; Pneumonia; Alveolar epithelial cell

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Calcium regulation in aortic smooth muscle cells during the initial phase of tunicamycin-induced endo/sarcoplasmic reticulum stress

Keywords: پاسخ پروتئین آشکار; Vascular smooth muscle cell; Endoplasmic reticulum stress; Unfolded protein response; Tunicamycin; Calcium;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Mitogen-activated protein kinases and protein phosphatase 5 mediate glucocorticoid-induced cytotoxicity in pancreatic islets and β-cells

Keywords: پاسخ پروتئین آشکار; ASK-1; apoptosis signal-regulating kinase 1; dexa; dexamethasone; eIF2α; eukaryotic translation initiation factor 2α; GC; glucocorticoid; GR; glucocorticoid receptor; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PP5; serine/thre

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Metabolic and transcriptional responses of gilthead sea bream (Sparus aurata L.) to environmental stress: New insights in fish mitochondrial phenotyping

Keywords: پاسخ پروتئین آشکار; ACAA2; 3-ketoacyl-CoA thiolase, mitochondrial; AIFM1; apoptosis-related protein 1; AIFM3; apoptosis-related protein 3; ANOVA; analysis of variance; BAX; apoptosis regulator BAX; BCL2; apoptosis regulator Bcl-2; BCLX; Bcl-2-like protein 1; CAT; catalase; C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Isolation and characterization of MdATG18a, a WD40-repeat AuTophaGy-related gene responsive to leaf senescence and abiotic stress in Malus

Keywords: پاسخ پروتئین آشکار; ATG18; AuTophaGy-related gene 18; CRL4; cullin4-RING ubiquitin ligase complex; Cvt; cytoplasm-to-vacuole targeting; DWD; DNA-binding WD40 proteins; EF-1α; elongation factor 1 alpha gene; ER; endoplasmic reticulum; MV; methyl viologen; ORF; open reading f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity

Keywords: پاسخ پروتئین آشکار; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ALS; amyotrophic lateral sclerosis; Ara C; (β-d-Arabinofuranosyl)cytosin; Bip; binding immunoglobulin protein/78 kDa glucose-regulated protein; CCM; cell conditioned medium; CHOP; C/EBP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Polyribosome and ribonucleoprotein complex redistribution of mRNA induced by GnRH involves both EIF2AK3 and MAPK signaling

Keywords: پاسخ پروتئین آشکار; Gonadotropins; Luteinizing hormone; Dusp1; Pituitary; Translation; Unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Association of nonsense mutation in GABRG2 with abnormal trafficking of GABAA receptors in severe epilepsy

Keywords: پاسخ پروتئین آشکار; GEFS+, genetic epilepsy with febrile seizures plus; PTCs, premature termination codons; NMD, nonsense-mediated decayChannelopathy; ER stress; Trafficking; Sorting; Unfolded protein response

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه