
Uncoupling of cytochrome P450 1A and stimulation of reactive oxygen species production by co-planar polychlorinated biphenyl congeners
Keywords: سیتوکروم P450; CYP1A; Reactive oxygen species; Planar halogenated aromatic hydrocarbons; Oxidative inactivationAHR, aryl hydrocarbon receptor; ANF, alpha-naphthoflavone; B[a]P, benzo[a]pyrene; CYP, cytochrome P450; DCF, 2′,7′-dichlorofluorescein; DCFHDA, 2′,7′-dichlorod