
Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity
Keywords: فاکتور رشد اپیدرمی; ADAMs, a disintegrin and metalloproteases; AP, alkaline phosphatase; CA, constitutively active; CT-B, cholera toxin subunit B; DAPI, 4′,6-diamidino-2-phenylindole; ECM, extracellular matrix; EGF, epidermal growth factor; EGFR, EGF receptor; FACS, fluoresc