Unlocking nature's CH bonds
Keywords: فرآورده های طبیعی; CH activation; Amino acid ligand; Pd catalyst; Natural products;
مقالات ISI فرآورده های طبیعی (ترجمه نشده)
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Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand
Keywords: فرآورده های طبیعی; ABC-transporter; ATP-binding cassette transporter; BBB; blood-brain barrier; Calcein-AM; calcein acetoxymethylester; EC50; 50% effective concentration; ECmax; maximal effective concentration; HPLC; high pressure liquid chromatography; IC50; 50% inhibito
Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs
Keywords: فرآورده های طبیعی; Asthma; Coumarins; Natural products; Pharmacophoric group; SAR; Tracheal rings(CH3CO)2O, acetic anhydride; μL, microliters; μM, micromolar; C4H7BrO2, ethyl bromoacetate; CaCl2, calcium chloride; cAMP, cyclic adenosine monophosphate; CDCl3, Deuterated chlo
Polyphenols in Barringtonia racemosa and their protection against oxidation of LDL, serum and haemoglobin
Keywords: فرآورده های طبیعی; Natural products; Extraction; Barringtonia racemosa; Polyphenols; Lipid peroxidation; Haemoglobin oxidation; UHPLC;
A high-resolution peak fractionation approach for streamlined screening of nuclear-factor-E2-related factor-2 activators in Salvia miltiorrhiza
Keywords: فرآورده های طبیعی; Natural products; High-resolution peak fractionation; Cell-based screening; Nrf2 activators; Salvia miltiorrhiza
Sesquiterpenoid glycosides from glandular trichomes of the wild tomato relative Solanum habrochaites
Keywords: فرآورده های طبیعی; NUHBBNIHNIYJFM-ARYWSNPOSA-N; ONZKIHDQZHGVBA-DSMBRBAFSA-N; CJPUZYHTTDRUHK-SIEUFYATSA-N; ZGRDRXDPBUJPBW-NWRPPJOHSA-N; Wild tomato; Solanum habrochaites; Solanaceae; Campherenane-2,12-diol; Glandular trichomes; Malonate esters; Metabolomics; Natural products
Anthelmintic activity in vitro and in vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni
Keywords: فرآورده های طبیعی; Baccharis trimera; Natural products; Schistosomiasis; Schistosomula; Juvenile worms; Schistosomicidial activity; Treatment;
Modulatory effects of morin on hyperglycemia by attenuating the hepatic key enzymes of carbohydrate metabolism and β-cell function in streptozotocin-induced diabetic rats
Keywords: فرآورده های طبیعی; Morin; Antidiabetic activity; STZ; Carbohydrate enzymes; Natural products
pH-Sensitive Nanoparticles of Curcumin-Celecoxib Combination: Evaluating Drug Synergy in Ulcerative Colitis Model
Keywords: فرآورده های طبیعی; colonic drug delivery; drug delivery systems; drug targeting; nanoparticles; natural products; oral drug delivery; polymeric drug carrier; site-specific delivery; targeted drug delivery;
Molecular diversity and body distribution of saponins in the sea star Asterias rubens by mass spectrometry
Keywords: فرآورده های طبیعی; Echinoderms; Saponins; Mass spectrometry; Structure elucidation; Natural products; LC-MS
Canadian boreal pulp and paper feedstocks contain neuroactive substances that interact in vitro with GABA and dopaminergic systems in the brain
Keywords: فرآورده های طبیعی; DA; dopamine; GABA; gamma-aminobutyric acid; MAO; monoamine oxidase; GAD; glutamic acid decarboxylase; GABA-T; GABA-transaminase; GABA(A)-BZD; GABA(A) receptor benzodiazepine-binding site; GnRH; gonadotropin-releasing hormone; LH; luteinizing hormone; Pul
Retention time prediction for dereplication of natural products (CxHyOz) in LC-MS metabolite profiling
Keywords: فرآورده های طبیعی; UHPLC; Retention time prediction; Natural products; Metabolite profiling; Dereplication;
Total synthesis and structural validation of cyclodepsipeptides solonamide A and B
Keywords: فرآورده های طبیعی; Natural products; Depsipeptides; Macrocycles; Quorum sensing; Virulence;
Total synthesis of burkholdacs A and B and 5,6,20-tri-epi-burkholdac A: HDAC inhibition and antiproliferative activity
Keywords: فرآورده های طبیعی; Burkholdacs; Histone deacetylase inhibitors; Natural products; Bicyclic depsipeptide; Total synthesis
A review of non-nucleoside anti-hepatitis B virus agents
Keywords: فرآورده های طبیعی; Hepatitis B virus; Inhibitor; Non-nucleoside; Small-molecule inhibitors; Natural products; Synthetic compounds
Marine actinobacteria: An important source of bioactive natural products
Keywords: فرآورده های طبیعی; Marine actinobacteria; Bioactive compounds; Chemical structures; Antibiotics; Natural products
Targeting death receptors for TRAIL by agents designed by Mother Nature
Keywords: فرآورده های طبیعی; cancer; death receptor; natural products; nutraceuticals; ROS; TRAIL; apoptosis
Caught between triterpene- and steroid-metabolism: 4α-Carboxylic pregnane-derivative from the marine alga-derived fungus Phaeosphaeria spartinae
Keywords: فرآورده های طبیعی; Phaeosphaeria spartinae; Pregnenolone; Natural products; Spartopregnenolone;
An asymmetric synthesis of the pentacyclic core of stemofoline
Keywords: فرآورده های طبیعی; Mannich reactions; Stereoselectivity; Natural products; Alkaloids;
TiCl4 mediated preparation of (E)-non-conjugated homoallylic alcohols with α-substituted allylsilanes
Keywords: فرآورده های طبیعی; Allylation; Allylsilane; Olefination; Natural products; Diastereoselective synthesis;
Enantioselective synthesis of a potential 1,5-syn-polyol C1-C24 subunit of (â)-caylobolide A
Keywords: فرآورده های طبیعی; Allylation; Conjugate addition; Natural products; Cross-metathesis; Caylobolide;
Synthesis of the non-peptidic snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT)2, its lower and higher thio homologs and their ability to modulate potassium ion channels
Keywords: فرآورده های طبیعی; Natural products; Ion channel inhibitors; Indoles; Thiolation; Electrophysiology;
Total synthesis of (±)-cis-trikentrin B via intermolecular 6,7-indole aryne cycloaddition and Stille cross-coupling
Keywords: فرآورده های طبیعی; Indole; Aryne; Benzofuran; Trikentrin; Herbindole; Natural products; Cycloaddition; Total synthesis; Stille; Cross-coupling;
A new synthesis of dehydroluciferin [2-(6â²-hydroxy-2â²-benzothiazolyl)-thiazole-4-carboxylic acid] from 1,4-benzoquinone
Keywords: فرآورده های طبیعی; Dehydroluciferin; Firefly luciferase; Natural products; Heterocycles; Total synthesis;
Synthesis of the acylphloroglucinols rhodomyrtone and rhodomyrtosone B
Keywords: فرآورده های طبیعی; Acylphloroglucinols; Natural products; Antibiotics; Knoevenagel condensation; Retro Friedel-Crafts acylation;
Synthesis of bis-tetrahydrofuran subunit of (â)-neopallavicinin
Keywords: فرآورده های طبیعی; Palladium(II)-catalysis; Iron pentacarbonyl; Oxycarbonylation; Natural products; Neopallavicinin;
Psammaplysin F: A unique inhibitor of bacterial chromosomal partitioning
Keywords: فرآورده های طبیعی; Natural products; Antibiotics; DNA; Amine; Cell division;
Natural products inspired synthesis of neuroprotective agents against H2O2-induced cell death
Keywords: فرآورده های طبیعی; IV; intravenous; FDA; food and drug administration; AIS; acute ischemic stroke; rt-PA; recombinant tissue plasminogen activator; NMR; nuclear magnetic resonance; NOE; nuclear overhauser effect; m-CPBA; meta-chloroperoxybenzoic acid; ORTEP; oak ridge therm
Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells
Keywords: فرآورده های طبیعی; Natural products; Liposomes; Bergamot essential oil (BEO); Citrus extracts; Cancer; SH-SY5Y human neuroblastoma cells;
Protective effects of sweroside on human MG-63 cells and rat osteoblasts
Keywords: فرآورده های طبیعی; Sweroside; Osteoporosis; MG-63 cells; Rat osteoblasts; Natural products;
Studies on α-glucosidase inhibition and anti-glycation potential of Iris loczyi and Iris unguicularis
Keywords: فرآورده های طبیعی; Diabetes; Hyperglycemia; α-glucosidase inhibition activity; Anti-glycation activity; Natural products;
Synthesis of the C1-C15 fragment of palmerolide A via protecting group dependent RCM reaction
Keywords: فرآورده های طبیعی; Natural products; Palmerolide A; Cytotoxic; Sharpless dihydroxylation; Heck coupling; Ring-closing metathesis reaction;
Bioactive metabolites from an endophytic Cryptosporiopsis sp. inhabiting Clidemia hirta
Keywords: فرآورده های طبیعی; Clidemia hirta; Endophytes; Natural products; Cytotoxicity; Antimicrobial activity; Cryptosporiopsis;
New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: Virtual screening and activity assays
Keywords: فرآورده های طبیعی; HIV-1 Integrase; LEDGF/p75; Protein-protein interaction inhibitors; LEDGINs; Natural products; Virtual screening; AIDS; acquired immunodeficiency syndrome; CCD; catalytic core domain; HIV-1; human immunodeficiency virus type 1; IBD; integrase binding do
The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations
Keywords: فرآورده های طبیعی; Bauhinia forficata; Diabetes mellitus; Natural products; Oxidative stress; Red blood cells; In vitro;
Cohaerins G-K, azaphilone pigments from Annulohypoxylon cohaerens and absolute stereochemistry of cohaerins C-K
Keywords: فرآورده های طبیعی; Annulohypoxylon cohaerens; Xylariaceae; Structure elucidation; Secondary metabolites; Natural products; Azaphilone; Cohaerin; Chemotaxonomy;
A general, flexible, ring closing metathesis (RCM) based strategy for accessing the fused furo[3,2-b]furanone moiety present in diverse bioactive natural products
Keywords: فرآورده های طبیعی; Ring closing metathesis; Furo[3,2-b]furanone; Natural products; Baylis-Hillman adducts; Sterically encumbered;
Development of a 13C-optimized 1.5-mm high temperature superconducting NMR probe
Keywords: فرآورده های طبیعی; HTS probe; Metabolomics; Natural products; 13C detection; High sensitivity;
A facile asymmetric synthesis of Î3-2-Hydroxybakuchiol, Bakuchiol and ent-Bakuchiol
Keywords: فرآورده های طبیعی; Natural products; Stereoselective synthesis; Cross-coupling; Unconjugated alkylation; Chiral quaternary carbon;
Phenylphenalenones and oxabenzochrysenones from the Australian plant Haemodorum simulans
Keywords: فرآورده های طبیعی; gHSQCAD; gradient heteronuclear single bond coherence adiabatic; Haemodorum simulans; Haemodoraceae; Phenylphenalenones; Oxabenzochrysenones; Natural products;
Intrinsic isotopic 13C labelling of polyphenols
Keywords: فرآورده های طبیعی; Isotope labelling; Stable isotope; Natural products; Phytochemistry; Polyphenols;
Organometallic Sn(II) catalyzing adducts of substituted benzaldehydes
Keywords: فرآورده های طبیعی; 23DBA; 2,3-dihydroxybenzoic acid; B3LYP; Becke, three-parameter, Lee-Yang-Parr functional (quantum chemical method); B3PW91; hybrid functional (quantum chemical method); COSY; (Homonuclear) correlation spectroscopy (Processing in NMR); CT; charge tran
Synthesis of (4S, 5S, 11R) and (4S, 5S, 11S)-iso-cladospolide B
Keywords: فرآورده های طبیعی; Butenolide; Singlet oxygen; Natural products; Total synthesis; γ-Lactone;
A putative terpene cyclase, vir4, is responsible for the biosynthesis of volatile terpene compounds in the biocontrol fungus Trichoderma virens
Keywords: فرآورده های طبیعی; Trichoderma; Natural products; Terpenes; Vir4; GC/MS;
Gram scale synthesis of the C(1)-C(9) fragment of amphidinolide C
Keywords: فرآورده های طبیعی; Amphidinolide; Aerobic oxidation; Asymmetric dihydroxylation; Hydrostannylation; Natural products;
Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria
Keywords: فرآورده های طبیعی; Bacterial cytoskeleton; Antibiotics; Natural products; Drug resistant bacteria;
Platelet-activating factor (PAF)-antagonists of natural origin
Keywords: فرآورده های طبیعی; In-vitro tests; Natural products; Platelet activating factor (PAF); Platelet activating factor receptor (PAFR); Signaling pathway;
In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model
Keywords: فرآورده های طبیعی; Aplysinopsin; Serotonin; Monoamine oxidase; Natural products; Depression;
Advances in serinals for asymmetric synthesis
Keywords: فرآورده های طبیعی; Serinals; Chiral pool synthesis; Unnatural amino acids; Ceramides; Natural products; Building blocks;
Keywords: فرآورده های طبیعی; Natural products; Sepsis target; Computational biology; Thrombin inhibition